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Cited by 1,494

The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.

Shared Risk Factors in Cardiovascular Disease and Cancer

Open access
Koene, Ryan J., Prizment, Anna E., Blaes, Anne, Konety, Suma H.·2016·Circulation

Abstract

Cardiovascular disease (CVD) and cancer are the 2 leading causes of death worldwide. Although commonly thought of as 2 separate disease entities, CVD and cancer possess various similarities and possible interactions, including a number of similar risk factors (eg, obesity, diabetes mellitus), suggesting a shared biology for which there is emerging evidence. Although chronic inflammation is an indispensable feature of the pathogenesis and progression of both CVD and cancer, additional mechanisms can be found at their intersection. Therapeutic advances, despite improving longevity, have increased the overlap between these diseases, with millions of cancer survivors now at risk of developing CVD. Cardiac risk factors have a major impact on subsequent treatment-related cardiotoxicity. In this review, we explore the risk factors common to both CVD and cancer, highlighting the major epidemiological studies and potential biological mechanisms that account for them.

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Crossref · 10.1161/circulationaha.115.020406

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Metadata

Authors
Koene, R. J., Prizment, A. E., Blaes, A., & Konety, S. H.
Venue
Circulation
Published
2016-03-15
Volume
133
Issue
11
Pages
1104-1114
ISSN
  • 0009-7322 (ISSN-L)
  • 1524-4539
OpenAlex
W2298991506
Cited by
1,494
References
16
FWCI
64.74
Type
journal article
Language
en
Open access
bronze

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.