Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy

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Items 101–200 of 797

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5. Insulin- and Leptin-Mediated Control of Aquaglyceroporins in Human Adipocytes and Hepatocytes Is Mediated via the PI3K/Akt/mTOR Signaling Cascade
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7. Osteoimmunology: Crosstalk Between the Immune and Bone Systems
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8. Serum adipocytokines are related to lipodystrophy and metabolic disorders in HIV-infected men under antiretroviral therapy
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9. Site and mechanism of leptin action in a rodent form of congenital lipodystrophy
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10. Site and mechanism of leptin action in a rodent form of congenital lipodystrophy
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11. Differential Accessibility of Circulating Leptin to Individual Hypothalamic Sites
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12. Brain insulin signalling in metabolic homeostasis and disease
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14. Hepatic glucose metabolism in humans—its role in health and disease
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15. Nutrition, insulin resistance and dysfunctional adipose tissue determine the different components of metabolic syndrome
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16. Excess body fat in obese and normal-weight subjects
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18. Reversal of muscle insulin resistance with exercise reduces postprandial hepatic de novo lipogenesis in insulin resistant individuals
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19. Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis
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20. FAT CELLS: Afferent and Efferent Messages Define New Approaches to Treat Obesity
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21. Leptin at the Intersection of Neuroendocrinology and Metabolism: Current Evidence and Therapeutic Perspectives
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22. Genetic variants in ABO blood group region, plasma soluble E-selectin levels and risk of type 2 diabetes
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23. Overexpression of uncoupling protein 3 in skeletal muscle protects against fat-induced insulin resistance
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24. Lipid droplet proteins and metabolic diseases
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25. Compensation by the muscle limits the metabolic consequences of lipodystrophy in PPARγ hypomorphic mice
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26. Role of SREBPs in Liver Diseases: A Mini-review
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27. PKCλ in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity
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29. Efficacy of leptin therapy in the different forms of human lipodystrophy
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30. Ectopic fat and cardiometabolic and vascular risk
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31. Roles for leptin receptor/STAT3-dependent and -independent signals in the regulation of glucose homeostasis
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32. Insulin and Leptin Resistance With Hyperleptinemia in Mice Lacking Androgen Receptor
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33. Adipose Tissue as an Endocrine Organ: An Update on Pro-inflammatory and Anti-inflammatory Microenvironment
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34. Leptin therapy, insulin sensitivity, and glucose homeostasis
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35. Adipose tissue expandability: the metabolic problems of obesity may arise from the inability to become more obese
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36. Whole body fat: Content and distribution
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37. Leptin as a predictive marker for metabolic syndrome
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38. Leptin and the Control of Metabolism: Role for Stearoyl-CoA Desaturase-1 (SCD-1)
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39. Recombinant methionyl human leptin therapy in replacement doses improves insulin resistance and metabolic profile in patients with lipoatrophy and metabolic syndrome induced by the highly active antiretroviral therapy.
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40. Hepatic Diacylglycerol-Associated Protein Kinase Cε Translocation Links Hepatic Steatosis to Hepatic Insulin Resistance in Humans
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41. Muscular diacylglycerol metabolism and insulin resistance
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42. The role of leptin in health and disease
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43. Antidiabetic effect of total saponins from Entada phaseoloides (L.) Merr. in type 2 diabetic rats
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44. Altered metabolic responses to intermittent hypoxia in mice with partial deficiency of hypoxia-inducible factor-1α
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45. Measuring body fat distribution and content in humans
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46. Lipid indices as simple and clinically useful surrogate markers for insulin resistance in the U.S. population
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47. Emerging Role of Adipocytokines in Type 2 Diabetes as Mediators of Insulin Resistance and Cardiovascular Disease
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48. Central nervous system regulation of organismal energy and glucose homeostasis
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49. Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function
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50. Dietary n-3 polyunsaturated fatty acids decrease hepatic triglycerides in Fischer 344 rats
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51. Determination of triglyceride in the human myocardium by magnetic resonance spectroscopy: reproducibility and sensitivity of the method
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52. Fatty acids and insulin resistance in muscle and liver
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53. Regulation of fat metabolism in the liver: link to non-alcoholic hepatic steatosis and impact of physical exercise
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54. Unraveling the Cellular Mechanism of Insulin Resistance in Humans: New Insights from Magnetic Resonance Spectroscopy
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55. Molecular mechanisms of human lipodystrophies: From adipocyte lipid droplet to oxidative stress and lipotoxicity
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56. Genetic Basis of Lipodystrophies and Management of Metabolic Complications
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57. Clinical Effects of Long-Term Metreleptin Treatment in Patients With Lipodystrophy
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58. ‘Endocrine NAFLD’ a hormonocentric perspective of nonalcoholic fatty liver disease pathogenesis
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59. Metabolic Actions of Adipocyte Hormones: Focus on Adiponectin
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60. Deletion of the α-Arrestin Protein Txnip in Mice Promotes Adiposity and Adipogenesis While Preserving Insulin Sensitivity
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61. The delicate balance between fat and muscle: adipokines in metabolic disease and musculoskeletal inflammation
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62. Deleterious action of FA metabolites on ATP synthesis: possible link between lipotoxicity, mitochondrial dysfunction, and insulin resistance
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63. ISPAD Clinical Practice Consensus Guidelines 2006?2007 The diagnosis and management of monogenic diabetes in children
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64. SREBP Regulation of Lipid Metabolism in Liver Disease, and Therapeutic Strategies
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65. Lipodystrophies: rare disorders causing metabolic syndrome
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66. There and Back Again: Leptin Actions in White Adipose Tissue
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67. Adipokines as regulators of muscle metabolism and insulin sensitivityThis paper is one of a selection of papers published in this Special Issue, entitled 14th International Biochemistry of Exercise Conference – Muscles as Molecular and Metabolic Machines, and has undergone the Journal’s usual peer review process.
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68. Type 2 Diabetes Remission Rates After Laparoscopic Gastric Bypass and Gastric Banding: Results of the Longitudinal Assessment of Bariatric Surgery Study
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69. Apolipoprotein CIII overexpressing mice are predisposed to diet-induced hepatic steatosis and hepatic insulin resistance
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70. Effects of HIV protease inhibitor therapy on lipid metabolism
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71. Mechanisms of intrahepatic triglyceride accumulation
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72. Changes in Insulin Resistance Following Bariatric Surgery and the Adipoinsular Axis: Role of the Adipocytokines, Leptin, Adiponectin and Resistin
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73. AMPK expression and phosphorylation are increased in rodent muscle after chronic leptin treatment
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74. Activation of the Leptin Receptor by a Ligand-induced Conformational Change of Constitutive Receptor Dimers
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75. Insulin resistance and steatosis in humans
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76. Effects of Exogenous Leptin on Satiety and Satiation in Patients with Lipodystrophy and Leptin Insufficiency
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77. Lipodystrophy Due to Adipose Tissue–Specific Insulin Receptor Knockout Results in Progressive NAFLD
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78. Molecular mechanisms of lipid‐induced insulin resistance in muscle, liver and vasculature
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79. Systematic review: adipose tissue, obesity and gastrointestinal diseases
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80. Leptin and the Proinflammatory State Associated with Human Obesity
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81. The effects of recombinant human leptin on visceral fat, dyslipidemia, and insulin resistance in patients with human immunodeficiency virus-associated lipoatrophy and hypoleptinemia
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82. The Role of Muscle Insulin Resistance in the Pathogenesis of Atherogenic Dyslipidemia and Nonalcoholic Fatty Liver Disease Associated with the Metabolic Syndrome
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83. Hepatic Steatosis, Insulin Resistance, and Adipose Tissue Disorders
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84. Leptin Dysfunction and Alzheimer’s Disease: Evidence from Cellular, Animal, and Human Studies
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85. Leptin Impairs Insulin Signaling in Rat Adipocytes
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86. Potential Nexus of Non-alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus: Insulin Resistance Between Hepatic and Peripheral Tissues
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87. Central insulin and leptin-mediated autonomic control of glucose homeostasis
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88. The role of leptin in diabetes: metabolic effects
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89. Brain leptin reduces liver lipids by increasing hepatic triglyceride secretion and lowering lipogenesis
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90. Fatty liver in lipodystrophy: A review with a focus on therapeutic perspectives of adiponectin and/or leptin replacement
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91. Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis
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92. Lipodystrophy: lessons in lipid and energy metabolism
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93. Improved β-cell function after standardized weight reduction in severely obese subjects
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94. Melanocortin-independent Effects of Leptin on Hepatic Glucose Fluxes
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95. Proteinuric Nephropathy in Acquired and Congenital Generalized Lipodystrophy: Baseline Characteristics and Course during Recombinant Leptin Therapy
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96. Liver Triglyceride Secretion and Lipid Oxidative Metabolism Are Rapidly Altered by Leptin in Vivo
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97. Recombinant Human Leptin Treatment Does Not Improve Insulin Action in Obese Subjects With Type 2 Diabetes
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98. Non-alcoholic fatty liver disease and insulin resistance: From bench to bedside
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99. Adipose tissue dysfunction and visceral fat are associated with hepatic insulin resistance and severity of NASH even in lean individuals
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