Muscle function and fat content in relation to sarcopenia, obesity and frailty of old age — An overview

Frailty in Older Adults: Evidence for a Phenotype

Fried, L. P., Tangen, C. M., Walston, J., Newman, A. B., Hirsch, C., Gottdiener, J., Seeman, T., Tracy, R., Kop, W. J., Burke, G., et al. (2001) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/56.3.m146 · Cited by 24,907 · see citing works

Sarcopenia: European consensus on definition and diagnosis

Cruz-Jentoft, A. J., Baeyens, J. P., Bauer, J. M., Boirie, Y., Cederholm, T., Landi, F., Martin, F. C., Michel, J.-P., Rolland, Y., Schneider, S. M., et al. (2010) · Age and Ageing · doi:10.1093/ageing/afq034 · Cited by 11,601 · see citing works

National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants

Finucane, M. M., Stevens, G. A., Cowan, M. J., Danaei, G., Lin, J. K., Paciorek, C. J., Singh, G. M., Gutierrez, H. R., Lu, Y., Bahalim, A. N., et al. (2011) · The Lancet · doi:10.1016/s0140-6736(10)62037-5 · Cited by 4,050 · see citing works

Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability

Janssen, I., Heymsfield, S. B., & Ross, R. (2002) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2002.50216.x · Cited by 3,139 · see citing works

The Loss of Skeletal Muscle Strength, Mass, and Quality in Older Adults: The Health, Aging and Body Composition Study

Goodpaster, B. H., Park, S. W., Harris, T. B., Kritchevsky, S. B., Nevitt, M., Schwartz, A. V., Simonsick, E. M., Tylavsky, F. A., Visser, M., Newman, A. B., et al. (2006) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/61.10.1059 · Cited by 3,083 · see citing works

Impaired Mitochondrial Activity in the Insulin-Resistant Offspring of Patients with Type 2 Diabetes

Petersen, K. F., Dufour, S., Befroy, D., Garcia, R., & Shulman, G. I. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa031314 · Cited by 2,193 · see citing works

Mitochondrial dysfunction in the elderly: possible role in insulin resistance

Petersen, K. F., Befroy, D., Dufour, S., Dziura, J., Ariyan, C., Rothman, D. L., DiPietro, L., Cline, G. W., & Shulman, G. I. (2003) · Science · doi:10.1126/science.1082889 · Cited by 2,107 · see citing works

Strength, But Not Muscle Mass, Is Associated With Mortality in the Health, Aging and Body Composition Study Cohort

Newman, A. B., Kupelian, V., Visser, M., Simonsick, E. M., Goodpaster, B. H., Kritchevsky, S. B., Tylavsky, F. A., Rubin, S. M., Harris, T. B., & on Behalf of the Health, A. A. B. C. S. I. (2006) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/61.1.72 · Cited by 1,692 · see citing works

Research Agenda for Frailty in Older Adults: Toward a Better Understanding of Physiology and Etiology: Summary from the American Geriatrics Society/National Institute on Aging Research Conference on Frailty in Older Adults

Walston, J., Hadley, E. C., Ferrucci, L., Guralnik, J. M., Newman, A. B., Studenski, S. A., Ershler, W. B., Harris, T., & Fried, L. P. (2006) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2006.00745.x · Cited by 1,605 · see citing works

Muscle Mass, Muscle Strength, and Muscle Fat Infiltration as Predictors of Incident Mobility Limitations in Well-Functioning Older Persons

Visser, M., Goodpaster, B. H., Kritchevsky, S. B., Newman, A. B., Nevitt, M., Rubin, S. M., Simonsick, E. M., Harris, T. B., & Study, F. T. H. A. (2005) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/60.3.324 · Cited by 1,403 · see citing works

Midlife cardiovascular risk factors and risk of dementia in late life

Whitmer, R. A., Sidney, S., Selby, J., Johnston, S. C., & Yaffe, K. (2005) · Neurology · doi:10.1212/01.wnl.0000149519.47454.f2 · Cited by 1,238 · see citing works

Ectopic Fat in Insulin Resistance, Dyslipidemia, and Cardiometabolic Disease

Shulman, G. I. (2014) · New England Journal of Medicine · doi:10.1056/nejmra1011035 · Cited by 1,126 · see citing works

Healthy life expectancy for 187 countries, 1990–2010: a systematic analysis for the Global Burden Disease Study 2010

Salomon, J. A., Wang, H., Freeman, M. K., Vos, T., Flaxman, A. D., Lopez, A. D., & Murray, C. J. (2012) · The Lancet · doi:10.1016/s0140-6736(12)61690-0 · Cited by 1,116 · see citing works

Obesity in middle age and future risk of dementia: a 27 year longitudinal population based study

Whitmer, R. A., Gunderson, E. P., Barrett-Connor, E., Quesenberry, C. P., & Yaffe, K. (2005) · BMJ · doi:10.1136/bmj.38446.466238.e0 · Cited by 1,090 · see citing works

Biodemography of human ageing

Vaupel, J. W. (2010) · Nature · doi:10.1038/nature08984 · Cited by 1,079 · see citing works

Designing Randomized, Controlled Trials Aimed at Preventing or Delaying Functional Decline and Disability in Frail, Older Persons: A Consensus Report

Ferrucci, L., Guralnik, J. M., Studenski, S., Fried, L. P., Cutler, G. B., Walston, J. D., & The Interventions on Frailty Working Group (2004) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2004.52174.x · Cited by 1,027 · see citing works

Prevalence of Frailty in Middle-Aged and Older Community-Dwelling Europeans Living in 10 Countries

Santos-Eggimann, B., Cuenoud, P., Spagnoli, J., & Junod, J. (2009) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/glp012 · Cited by 963 · see citing works

Longitudinal Muscle Strength Changes in Older Adults: Influence of Muscle Mass, Physical Activity, and Health

HUGHES, V. A., Frontera, W. R., Wood, M., Evans, W. J., Dallal, G. E., Roubenoff, R., & Singh, M. A. F. (2001) · The Journals of Gerontology Series A · doi:10.1093/gerona/56.5.b209 · Cited by 924 · see citing works

Sarcopenia != Dynapenia

Clark, B. C., & Manini, T. M. (2008) · The Journals of Gerontology Series A · doi:10.1093/gerona/63.8.829 · Cited by 876 · see citing works

Sarcopenia: origins and clinical relevance

Rosenberg, I. H. (2011) · Clinics in Geriatric Medicine · doi:10.1016/j.cger.2011.03.003 · Cited by 786 · see citing works

Sarcopenia: etiology, clinical consequences, intervention, and assessment

Lang, T., Streeper, T., Cawthon, P. M., Baldwin, K., Taaffe, D. R., & Harris, T. B. (2009) · Osteoporosis International · doi:10.1007/s00198-009-1059-y · Cited by 780 · see citing works

Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance

Kim, J. K., Fillmore, J. J., Chen, Y., Yu, C., Moore, I. K., Pypaert, M., Lutz, E. P., Kako, Y., Velez-Carrasco, W., Goldberg, I. J., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.121164498 · Cited by 753 · see citing works

Brain structure and obesity

Raji, C. A., Ho, A. J., Parikshak, N., Becker, J. T., López, O. L., Kuller, L. H., Hua, X., Leow, A., Toga, A. W., & Thompson, P. M. (2009) · Human Brain Mapping · doi:10.1002/hbm.20870 · Cited by 692 · see citing works

Frailty Syndrome: A Transitional State in a Dynamic Process

Lang, P. O., Michel, J., & Zekry, D. (2009) · Gerontology · doi:10.1159/000211949 · Cited by 672 · see citing works

Effects of Aging on Muscle Fibre Type and Size

Deschenes, M. R. (2004) · Sports Medicine · doi:10.2165/00007256-200434120-00002 · Cited by 671 · see citing works

Intermuscular fat: a review of the consequences and causes

Addison, O., Marcus, R. L., LaStayo, P. C., & Ryan, A. S. (2014) · International Journal of Endocrinology · doi:10.1155/2014/309570 · Cited by 656 · see citing works

The Role of Muscle Loss in the Age-Related Decline of Grip Strength: Cross-Sectional and Longitudinal Perspectives

Kallman, D. A., Plato, C. C., & Tobin, J. D. (1990) · Journal of Gerontology · doi:10.1093/geronj/45.3.m82 · Cited by 629 · see citing works

Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy

Petersen (2002) · Journal of Clinical Investigation · doi:10.1172/jci0215001 · Cited by 622 · see citing works

Association Between Regional Adipose Tissue Distribution and Both Type 2 Diabetes and Impaired Glucose Tolerance in Elderly Men and Women

Goodpaster, B. H., Krishnaswami, S., Resnick, H., Kelley, D. E., Haggerty, C., Harris, T. B., Schwartz, A. V., Kritchevsky, S., & Newman, A. B. (2003) · Diabetes Care · doi:10.2337/diacare.26.2.372 · Cited by 619 · see citing works

Sarcopenic obesity: prevalence and association with metabolic syndrome in the Korean longitudinal study on health and aging (KLoSHA)

Lim, S., Kim, J. H., Yoon, J. W., Kang, S. M., Choi, S. H., Park, Y. J., Kim, K. W., Lim, J. Y., Park, K. S., & Jang, H. C. (2010) · Diabetes Care · doi:10.2337/dc10-0107 · Cited by 588 · see citing works

Prevalence and Determinant Factors of Sarcopenia in Patients With Type 2 Diabetes

Kim, T. N., Park, M. S., Yang, S. J., Yoo, H. J., Kang, H. J., Song, W., Seo, J. A., Kim, S. G., Kim, N. H., Baik, S. H., et al. (2010) · Diabetes Care · doi:10.2337/dc09-2310 · Cited by 585 · see citing works

Difficulties with physical function associated with obesity, sarcopenia, and sarcopenic-obesity in community-dwelling elderly women: the EPIDOS (EPIDemiologie de l’OSteoporose) Study

Rolland, Y., Lauwers-Cances, V., Cristini, C., van Kan, G. A., Janssen, I., Morley, J. E., & Vellas, B. (2009) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26950 · Cited by 465 · see citing works

Influence of Sarcopenia on the Development of Physical Disability: The Cardiovascular Health Study

Janssen, I. (2006) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2005.00540.x · Cited by 459 · see citing works

Physical frailty and body composition in obese elderly men and women

Villareal, D. T., Banks, M., Siener, C., Sinacore, D. R., & Klein, S. (2004) · Obesity Research · doi:10.1038/oby.2004.111 · Cited by 459 · see citing works

Frailty, Body Mass Index, and Abdominal Obesity in Older People

Hubbard, R. E., Lang, I., Llewellyn, D. J., & Rockwood, K. J. (2009) · The Journals of Gerontology Series A · doi:10.1093/gerona/glp186 · Cited by 459 · see citing works

Sarcopenic Obesity: The Confluence of Two Epidemics

Roubenoff, R. (2004) · Obesity Research · doi:10.1038/oby.2004.107 · Cited by 453 · see citing works

Impaired Mitochondrial Substrate Oxidation in Muscle of Insulin-Resistant Offspring of Type 2 Diabetic Patients

Befroy, D. E., Petersen, K. F., Dufour, S., Mason, G. F., de Graaf, R. A., Rothman, D. L., & Shulman, G. I. (2007) · Diabetes · doi:10.2337/db06-0783 · Cited by 453 · see citing works

Effects of physical activity on strength and skeletal muscle fat infiltration in older adults: a randomized controlled trial

Goodpaster, B. H., Chomentowski, P., Ward, B. K., Rossi, A., Glynn, N. W., Delmonico, M. J., Kritchevsky, S. B., Pahor, M., & Newman, A. B. (2008) · Journal of Applied Physiology · doi:10.1152/japplphysiol.90425.2008 · Cited by 446 · see citing works

The Association Between Obesity and the Frailty Syndrome in Older Women: The Women's Health and Aging Studies

Blaum, C. S., Xue, Q., Michelon, E., Semba, R. D., & Fried, L. P. (2005) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2005.53300.x · Cited by 433 · see citing works

What is dynapenia?

Clark, B., & Manini, T. (2012) · Nutrition (Burbank, Los Angeles County, Calif.) · doi:10.1016/j.nut.2011.12.002 · Cited by 415 · see citing works

J apan as the front‐runner of super‐aged societies: Perspectives from medicine and medical care in J apan

Arai, H., Ouchi, Y., Toba, K., Endo, T., Shimokado, K., Tsubota, K., Matsuo, S., Mori, H., Yumura, W., Yokode, M., et al. (2015) · Geriatrics and gerontology international/Geriatrics & gerontology international · doi:10.1111/ggi.12450 · Cited by 409 · see citing works

Prevalence of sarcopenia and sarcopenic obesity in Korean adults: the Korean sarcopenic obesity study

Kim, T. N., Yang, S. J., Yoo, H. J., Lim, K. I., Kang, H. J., Song, W., Seo, J. A., Kim, S. G., Kim, N. H., Baik, S. H., et al. (2009) · International Journal of Obesity · doi:10.1038/ijo.2009.130 · Cited by 401 · see citing works

A 24-year follow-up of body mass index and cerebral atrophy

Gustafson, D., Lissner, L., Bengtsson, C., Björkelund, C., & Skoog, I. G. (2004) · Neurology · doi:10.1212/01.wnl.0000141850.47773.5f · Cited by 339 · see citing works

Reduced physical activity increases intermuscular adipose tissue in healthy young adults

Manini, T. M., Clark, B. C., Nalls, M. A., Goodpaster, B. H., Ploutz-Snyder, L. L., & Harris, T. B. (2007) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/85.2.377 · Cited by 332 · see citing works

Aging in adipocytes: Potential impact of inherent, depot-specific mechanisms

CARTWRIGHT, M., TCHKONIA, T., & KIRKLAND, J. (2007) · Experimental Gerontology · doi:10.1016/j.exger.2007.03.003 · Cited by 318 · see citing works

Sarcopenic/Obesity and Physical Capacity in Older Men and Women: Data From the Nutrition as a Determinant of Successful Aging (NuAge)—the Quebec Longitudinal Study

Bouchard, D. R., Dionne, I. J., & Brochu, M. (2009) · Obesity · doi:10.1038/oby.2009.109 · Cited by 314 · see citing works

Sarcopenic-obesity and cardiovascular disease risk in the elderly

Stephen, W. C., & Janssen, I. (2009) · The Journal of nutrition, health and aging · doi:10.1007/s12603-009-0084-z · Cited by 301 · see citing works

Life Course Social and Health Conditions Linked to Frailty in Latin American Older Men and Women

Alvarado, B., Zunzunegui, M. V., Béland, F., & Bamvita, J. (2008) · The Journals of Gerontology Series A · doi:10.1093/gerona/63.12.1399 · Cited by 298 · see citing works

Intramuscular adipose tissue, sarcopenia, and mobility function in older individuals

Marcus, R. L., Addison, O., Dibble, L. E., Foreman, K. B., Morrell, G., & LaStayo, P. (2012) · Journal of Aging Research · doi:10.1155/2012/629637 · Cited by 296 · see citing works

Structural brain differences and cognitive functioning related to body mass index in older females

Walther, K., Birdsill, A. C., Glisky, E. L., & Ryan, L. (2010) · Human Brain Mapping · doi:10.1002/hbm.20916 · Cited by 290 · see citing works

Body composition and its association with cardiometabolic risk factors in the elderly: A focus on sarcopenic obesity

Chung, J.-Y., Kang, H.-T., Lee, D.-C., Lee, H.-R., & Lee, Y.-J. (2013) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2012.09.007 · Cited by 283 · see citing works

Cytokines Promote Wnt Signaling and Inflammation and Impair the Normal Differentiation and Lipid Accumulation in 3T3-L1 Preadipocytes

Gustafson, B., & Smith, U. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m512077200 · Cited by 261 · see citing works

Exercise as a remedy for sarcopenia

Landi, F., Marzetti, E., Martone, A. M., Bernabei, R., & Onder, G. (2013) · Current Opinion in Clinical Nutrition and Metabolic Care · doi:10.1097/mco.0000000000000018 · Cited by 255 · see citing works

Relation of Obesity to Cognitive Function: Importance of Central Obesity and Synergistic Influence of Concomitant Hypertension. The Framingham Heart Study

Wolf, P., Beiser, A., Elias, M., Au, R., Vasan, R., & Seshadri, S. (2007) · Current Alzheimer Research · doi:10.2174/156720507780362263 · Cited by 254 · see citing works

Relationship between muscle mass and muscle strength, and the impact of comorbidities: a population-based, cross-sectional study of older adults in the United States

Chen, L., Nelson, D. R., Zhao, Y., Cui, Z. L., & Johnston, J. A. (2013) · BMC Geriatrics · doi:10.1186/1471-2318-13-74 · Cited by 238 · see citing works

The Epidemiology of Sarcopenia

Janssen, I. (2011) · Clinics in Geriatric Medicine · doi:10.1016/j.cger.2011.03.004 · Cited by 191 · see citing works

Understanding frailty

Lally, F., & Crome, P. (2007) · Postgraduate Medical Journal · doi:10.1136/pgmj.2006.048587 · Cited by 189 · see citing works

Sarcopenia – The search for emerging biomarkers

Kalinkovich, A., & Livshits, G. (2015) · Ageing Research Reviews · doi:10.1016/j.arr.2015.05.001 · Cited by 187 · see citing works

Body Mass Index, Muscle Strength and Physical Performance in Older Adults from Eight Cohort Studies: The HALCyon Programme

Hardy, R., Cooper, R., Sayer, A. A., Ben‐Shlomo, Y., Cooper, C. C., Deary, I. J., Demakakos, P., Gallacher, J., Martin, R. M., McNeill, G., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0056483 · Cited by 183 · see citing works

Metabolic syndrome and dementia risk in a multiethnic elderly cohort

Muller, M., Tang, M.-X., Schupf, N., Manly, J. J., Mayeux, R., & Luchsinger, J. A. (2007) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000105927 · Cited by 175 · see citing works

Sarcopenic obesity and dynapenic obesity: 5-year associations with falls risk in middle-aged and older adults: Falls Risk in Sarcopenic and Dynapenic Obesity

Scott, D., Sanders, K. M., Aitken, D., Hayes, A., Ebeling, P. R., & Jones, G. (2014) · Obesity · doi:10.1002/oby.20734 · Cited by 141 · see citing works

Impact of visceral fat on skeletal muscle mass and vice versa in a prospective cohort study: the Korean sarcopenic obesity study (KSOS)

Kim, T. N., Park, M. S., Ryu, J. Y., Choi, H. Y., Hong, H. C., Yoo, H. J., Kang, H. J., Song, W., Park, S. W., Baik, S. H., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0115407 · Cited by 133 · see citing works

Predictors of Ectopic Fat Accumulation in Liver and Pancreas in Obese Men and Women

Rossi, A. P., Fantin, F., Zamboni, G. A., Mazzali, G., Rinaldi, C. A., Giglio, M. D., Francesco, V. D., Barillari, M., Mucelli, R. P., & Zamboni, M. M. (2011) · Obesity · doi:10.1038/oby.2011.114 · Cited by 126 · see citing works

Overexpressing Human Lipoprotein Lipase in Mouse Skeletal Muscle Is Associated With Insulin Resistance

Ferreira, L. D., Pulawa, L. K., Jensen, D. R., & Eckel, R. H. (2001) · Diabetes · doi:10.2337/diabetes.50.5.1064 · Cited by 121 · see citing works

Body mass index and cognitive decline in a biracial community population

Sturman, M. T., de Leon, C. F. M., Bienias, J. L., Morris, M. C., Wilson, R. S., & Evans, D. A. (2007) · Neurology · doi:10.1212/01.wnl.0000285081.04409.bb · Cited by 119 · see citing works

Endocrine Crosstalk Between Muscle and Bone

Brotto, M. A. P., & Johnson, M. L. (2014) · Current Osteoporosis Reports · doi:10.1007/s11914-014-0209-0 · Cited by 118 · see citing works

Body mass index and white matter lesions in elderly women. An 18-year longitudinal study

Gustafson, D., Steen, B., & Skoog, I. G. (2004) · International Psychogeriatrics · doi:10.1017/s1041610204000353 · Cited by 117 · see citing works

Irisin and myonectin regulation in the insulin resistant muscle: implications to adipose tissue: muscle crosstalk

Gamas, L., Matafome, P., & Seiça, R. (2015) · Journal of Diabetes Research · doi:10.1155/2015/359159 · Cited by 114 · see citing works

Insulin Resistance and Executive Dysfunction in Older Persons

Abbatecola, A. M., Paolisso, G., Lamponi, M., Bandinelli, S., Lauretani, F., Launer, L. J., & Ferrucci, L. (2004) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2004.52466.x · Cited by 113 · see citing works

Sarcopenic Obesity and Cognitive Functioning: The Mediating Roles of Insulin Resistance and Inflammation?

Levine, M. E., & Crimmins, E. M. (2012) · Current Gerontology and Geriatrics Research · doi:10.1155/2012/826398 · Cited by 75 · see citing works

Roles of Chronic Low-Grade Inflammation in the Development of Ectopic Fat Deposition

Liu, L., Mei, M., Yang, S., & Li, Q. (2014) · Mediators of Inflammation · doi:10.1155/2014/418185 · Cited by 71 · see citing works

Research with children of prisoners: Methodological considerations for bringing youth in from the margins

Flynn, C. A., & Saunders, V. (2015) · Research Bank (Australian Catholic University) · Cited by 59 · see citing works

TNFα gene knockout differentially affects lipid deposition in liver and skeletal muscle of high-fat-diet mice

Salles, J., Tardif, N., Landrier, J., Mothe‐Satney, I., Guillet, C., Vaysse, C., Combaret, L., Giraudet, C., Patrac, V., Bertrand‐Michel, J., et al. (2012) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2011.12.001 · Cited by 50 · see citing works

Interleukin-6 and obesity

El-Kadre, L. J., & TINOCO, A. C. D. A. (2013) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0b013e32836410e6 · Cited by 41 · see citing works

Sarcopenic obesity or obese sarcopenia: A cross talk between age-associated adipose tissue and skeletal muscle inflammation as a main mechanism of the pathogenesis

Kalinkovich, A., & Livshits, G. (2017) · Ageing Research Reviews · doi:10.1016/j.arr.2016.09.008 · Cited by 882 · see citing works

Association Between Sarcopenia and Cognitive Impairment: A Systematic Review and Meta-Analysis

Chang, K. C., Hsu, T.-H., Wu, W., Huang, K., & Han, D. (2016) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2016.09.013 · Cited by 448 · see citing works

Gut Microbiota, Muscle Mass and Function in Aging: A Focus on Physical Frailty and Sarcopenia

Ticinesi, A., Nouvenne, A., Cerundolo, N., Catania, P., Prati, B., Tana, C., & Meschi, T. (2019) · Nutrients · doi:10.3390/nu11071633 · Cited by 418 · see citing works

Associations of Muscle Mass and Strength with All-Cause Mortality among US Older Adults

LI, R., XIA, J., ZHANG, X., GATHIRUA-MWANGI, W. G., GUO, J., LI, Y., MCKENZIE, S., & SONG, Y. (2018) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000001448 · Cited by 398 · see citing works

Sarcopenia during COVID-19 lockdown restrictions: long-term health effects of short-term muscle loss

Kirwan, R., McCullough, D., Butler, T., de Heredia, F. P., Davies, I. G., & Stewart, C. E. (2020) · GeroScience · doi:10.1007/s11357-020-00272-3 · Cited by 331 · see citing works

Effect of a Prebiotic Formulation on Frailty Syndrome: A Randomized, Double-Blind Clinical Trial

Buigues, C., Fernández-Garrido, J., Pruimboom, L., Hoogland, A., Navarro-Martínez, R., Martínez-Martínez, M., Verdejo, Y., Mascarós, M., Peris, C., & Cauli, O. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17060932 · Cited by 222 · see citing works

Physical activity, aging, and physiological function

Harridge, S. D. R., & Lazarus, N. R. (2017) · Physiology · doi:10.1152/physiol.00029.2016 · Cited by 214 · see citing works

The Role of Muscle Mass Gain Following Protein Supplementation Plus Exercise Therapy in Older Adults with Sarcopenia and Frailty Risks: A Systematic Review and Meta-Regression Analysis of Randomized Trials

Liao, C.-D., Chen, H.-C., Huang, S.-W., & Liou, T.-H. (2019) · Nutrients · doi:10.3390/nu11081713 · Cited by 189 · see citing works

The Association Between Sarcopenia and Diabetes: From Pathophysiology Mechanism to Therapeutic Strategy

Chen, H., Huang, X., Dong, M., Wen, S., Zhou, L., & Yuan, X. (2023) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s410834 · Cited by 180 · see citing works

Double burden of malnutrition in persons with obesity

Barazzoni, R., & Cappellari, G. G. (2020) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-020-09578-1 · Cited by 125 · see citing works

Obesity and Bone Health: A Complex Relationship

Piñar-Gutiérrez, A., García‐Fontana, C., García-Fontana, B., & Muñoz‐Torres, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23158303 · Cited by 119 · see citing works

Sarcopenia Is a Cause and Consequence of Metabolic Dysregulation in Aging Humans: Effects of Gut Dysbiosis, Glucose Dysregulation, Diet and Lifestyle

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Sarcopenia is attenuated by TRB3 knockout in aging mice via the alleviation of atrophy and fibrosis of skeletal muscles

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Chua, K. Y., Lin, X., Lim, W. S., & Koh, W. (2022) · Aging Clinical and Experimental Research · doi:10.1007/s40520-022-02167-z · Cited by 13 · see citing works

Eicosapentaenoic acid changes muscle transcriptome and intervenes in aging-related fiber type transition in male mice

Yamazaki, H., Nishimura, M., Uehara, M., Souta-Kuribara, A., Yamamoto, M., Yoshikawa, N., Morohashi, K.-I., & Tanaka, H. (2020) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00184.2020 · Cited by 13 · see citing works

The Metabolic Syndrome and the Phenotype of Frailty: A Causal Link?

Viscogliosi, G., Andreozzi, P., Ettorre, E., & Chiriac, I. M. (2016) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2016.06.018 · Cited by 13 · see citing works

Calorie Intake and Cognitive Function in the Elderly: Data from the Korean Frailty and Aging Cohort Study (KFACS)

Park, J., Lee, J.-H., Kim, Y., Won, C. W., & Kim, Y. (2019) · The journal of nutrition health & aging · doi:10.1007/s12603-019-1249-z · Cited by 13 · see citing works

Effects of short-term strength training on body composition, muscle strength and functional capacity of elderly: a systematic review and meta-analysis.

Moreira, O. C., Oliveira, C. E. P. D., Maroto-Izquierdo, S., Cuevas, M. J., & De Paz, J. A. (2019) · Bioscience Journal · doi:10.14393/bj-v35n6a2019-42775 · Cited by 11 · see citing works

An Examination of a Novel Weight Loss Supplement on Anthropometry and Indices of Cardiovascular Disease Risk

Sowinski, R. J., Grubic, T., Dalton, R., Schlaffer, J., Reyes, A., Jenkins, V. M., Williamson, S. L., Rasmussen, C. J., Murano, P. S., Earnest, C. P., et al. (2020) · Journal of Dietary Supplements · doi:10.1080/19390211.2020.1786207 · Cited by 12 · see citing works

Age-Dependent Differences of Paraspinal Muscle Endurance and Morphology in Chinese Community Population Without Chronic Low Back Pain

Han, G., Wang, W., Yue, L., Fan, Z., Li, Z., Li, J., Sun, Z., & Li, W. (2022) · Global Spine Journal · doi:10.1177/21925682221103507 · Cited by 12 · see citing works

Besonderheiten beim elektiven Hüftgelenkersatz des älteren Menschen

Claßen, T., Scheid, C., Landgraeber, S., & Jäger, M. (2016) · Der Orthopäde · doi:10.1007/s00132-016-3364-4 · Cited by 12 · see citing works

Sesamol Alleviates Sarcopenia via Activating AKT/mTOR/FoxO1 Signal Pathway in Aged Obese Mice

Yang, J., Wang, Z., Xie, Y., Tang, Y., Fu, Y., Xu, Z., Chen, J., & Qin, H. (2024) · Plant Foods for Human Nutrition · doi:10.1007/s11130-024-01199-2 · Cited by 11 · see citing works

Sensor-Based Upper-Extremity Frailty Assessment for the Vascular Surgery Risk Stratification

Yanquez, F. J., Peterson, A., Weinkauf, C. C., Goshima, K. R., Zhou, W., Mohler, J. M., Ehsani, H., & Toosizadeh, N. (2019) · Journal of Surgical Research · doi:10.1016/j.jss.2019.09.029 · Cited by 11 · see citing works

Net protein balance correlates with expression of autophagy, mitochondrial biogenesis, and fat metabolism‐related genes in skeletal muscle from older adults

Wu, H., Jang, J., Dridi, S., Ferrando, A. A., Wolfe, R. R., Kim, I., & Baum, J. (2020) · Physiological Reports · doi:10.14814/phy2.14575 · Cited by 10 · see citing works

Parution de livres

(2011) · L Encéphale · doi:10.1016/j.encep.2011.07.005

Association between sarcopenic obesity and risk of frailty in older adults: a systematic review and meta-analysis

Gengxin, Y., Xuehan, M., Xinyu, W., Yali, Y., Yiran, X., Zheng, L., Qiu, Y., Li, G., & Chen, L. (2024) · Age and Ageing · doi:10.1093/ageing/afae286 · Cited by 52 · see citing works

Sarcopenia, Sarcopenic Obesity and Frailty in Older Adults

Nagaratnam, N., & Nagaratnam, S. A. (2018) · Springer eBooks · doi:10.1007/978-3-319-96998-5_30 · Cited by 1 · see citing works

Crosstalk between Fat, Bone Mineral Density, Muscle, and Frailty

Copete, A. M. A., Rivas, D., & Duque, G. (2025) · CRC Press eBooks · doi:10.1201/9781003398295-5

Metabolism and Antiaging Medicine: Sarcopenic Obesity and Antiaging

Hamaguchi, M. (2024) · Springer eBooks · doi:10.1007/978-981-97-8514-8_41