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Cited by 1,166

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Age and bone mass as predictors of fracture in a prospective study.

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Hui, S L, Slemenda, C W, Johnston, C C·1988·Journal of Clinical Investigation

Abstract

To study the effect of bone mass on the risk of fracture, we followed 521 Caucasian women over an average of 6.5 yr and took repeated bone mass measurements at the radius. We observed 138 nonspinal fractures in 3,388 person-yr. The person-years of follow-up and the incident fractures were cross-classified by age and bone mass. The incidence of fracture was then fitted to a log-linear model in age and bone mass. It was found that incidence of fracture increased with both increasing age and decreasing radius bone mass. When subsets of fractures were examined it was found that age was a stronger predictor of hip fractures, whereas midshaft radius bone mass was a stronger predictor of fractures at the distal forearm. We concluded that bone mass is a useful predictor of fractures but that other age-related factors associated with fractures need to be identified.

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Metadata

Authors
Hui, S. L., Slemenda, C. W., & Johnston, C. C.
Venue
Journal of Clinical Investigation
Published
1988-06-01
Volume
81
Issue
6
Pages
1804-1809
ISSN
0021-9738 (ISSN-L)
OpenAlex
W2052533937
Cited by
1,166
References
0
FWCI
29.16
Type
journal article
Language
en
Open access
green

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