Cited by 1,137SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesCOVID-19 epidemiological studies

The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.

SARS-CoV-2: a storm is raging

Open access

Pedersen, Savannah F., Ho, Ya-Chi·2020·Journal of Clinical Investigation

DOI 10.1172/jci137647PMC PMC7190904

Open this paper in CoChat — free account Open PDF

Abstract

A rapidly expanding pandemicIn early December 2019, several local health facilities first reported pneumonia cases of unknown origin in Wuhan, China.This new coronavirus infectious disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was first reported on December 1, 2020 and identified as a previously unknown betacoronavirus (1, 2).Since then, studies have increasingly demonstrated that SARS-CoV-2 can be transmitted effectively among humans through aerosol or fomites (3-5).With transmission capabilities even before symptom onset (6, 7), this pandemic is rapidly evolving and expanding.As of April 2, 2020, a total of 962,977 confirmed cases of COVID-19 and 49,180 deaths have been reported across 180 countries and regions.Recent models indicated that as much as 86% of all infections early in the spread were undocumented, suggesting the real number of infections is likely much greater (8).As a public health emergency of international concern, COVID-19 was declared a pandemic by the World Health Organization.Public health authorities around the globe are now racing to contain the spread.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1172/jci137647

Cites

25 of 25 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Huang, C., Wang, Y., Li, X., Ren, L., Zhao, J., Hu, Y., Zhang, L., Fan, G., Xu, J., Gu, X., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30183-5 · Cited by 48,884
Clinical characteristics of coronavirus disease 2019 in China
Guan, W.-J., Ni, Z.-Y., Hu, Y., Liang, W.-H., Ou, C.-Q., He, J.-X., Liu, L., Shan, H., Lei, C.-L., Hui, D. S. C., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2002032 · Cited by 30,246
A novel coronavirus from patients with pneumonia in China, 2019
Zhu, N., Zhang, D., Wang, W., Li, X., Yang, B., Song, J., Zhao, X., Huang, B., Shi, W., Lu, R., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2001017 · Cited by 28,244
Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia
Li, Q., Guan, X., Wu, P., Wang, X., Zhou, L., Tong, Y., Ren, R., Leung, K. S. M., Lau, E. H. Y., Wong, J. Y., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2001316 · Cited by 16,575
Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding
Lu, R., Zhao, X., Li, J., Niu, P., Yang, B., Wu, H., Wang, W., Song, H., Huang, B., Zhu, N., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30251-8 · Cited by 11,907
Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV-1
van Doremalen, N., Bushmaker, T., Morris, D. H., Holbrook, M. G., Gamble, A., Williamson, B. N., Tamin, A., Harcourt, J. L., Thornburg, N. J., Gerber, S. I., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmc2004973 · Cited by 9,951
A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster
Chan, J., Yuan, S.-F., Kok, K.-H., To, K., Chu, H., Yang, J., Xing, F., Liu, J.-L., Yip, C., Poon, R., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30154-9 · Cited by 8,450
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
Yan, R., Zhang, Y., Li, Y., Xia, L., Guo, Y., & Zhou, Q. (2020) · Science · doi:10.1126/science.abb2762 · Cited by 5,036
Clinical and immunological features of severe and moderate coronavirus disease 2019
Chen, G., Wu, D., Guo, W., Cao, Y., Huang, D., Wang, H., Wang, T., Zhang, X., Chen, H., Yu, H., et al. (2020) · Journal of Clinical Investigation · doi:10.1172/jci137244 · Cited by 4,750
Presumed Asymptomatic Carrier Transmission of COVID-19
Bai, Y., Yao, L., Wei, T., Tian, F., Jin, D., Chen, L., & Wang, M. (2020) · JAMA · doi:10.1001/jama.2020.2565 · Cited by 4,496

Show all 23 references

Sorted by citations

Items 701–800 of 1,000

The Impact of COVID-19 Quarantine on Tuberculosis and Diabetes Mellitus Cases: A Modelling Study
Nuraini, N., Fauzi, I. S., Lestari, B. W., & Rizqina, S. (2022) · Tropical Medicine and Infectious Disease · doi:10.3390/tropicalmed7120407 · Cited by 8
Liver manifestations in COVID-19 patients: A review article
Helou, M. C., Nasr, J., Osta, N. E., Jabbour, E., & Husni, R. (2023) · World Journal of Clinical Cases · doi:10.12998/wjcc.v11.i10.2189 · Cited by 9
Human Endogenous Retrovirus, SARS-CoV-2, and HIV Promote PAH via Inflammation and Growth Stimulation
Wang, D., Gomes, M. T., Mo, Y., Prohaska, C. C., Zhang, L., Chelvanambi, S., Clauss, M. A., Zhang, D., Machado, R. F., Gao, M., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24087472 · Cited by 9
“The reduction in CD4+ T cell counts in HIV patients correlates with the severity of SARS-CoV-2 infection [80].”
Background
The single-cell landscape of immunological responses of CD4+ T cells in HIV versus severe acute respiratory syndrome coronavirus 2
Collora, J. A., Liu, R., Albrecht, K., & Ho, Y. (2020) · Current Opinion in HIV and AIDS · doi:10.1097/coh.0000000000000655 · Cited by 8
“Unlike HIV-1 infection, cytokine dysregulation in SARS-CoV-2 infection induces cytokine release syndrome (or cytokine storm), an acute systemic inflammatory syndrome that involves multiorgan dysfunction [16,17].”
BackgroundSelf-citation
COVID-19 and the Kidneys: Risk, Damage and Sequelae
Herrera-Valdés, R., Almaguer-López, M., López-Marín, L., Bacallao-Méndez, R., Jorge, F., & Guerra-Bustillo, G. (2020) · MEDICC Review · doi:10.37757/mr2020.v22.n4.10 · Cited by 8
“All these are conducive to kidney injury and imply a poor prognosis.[10]”
Background
Secondary metabolites of Alternaria alternate appraisal of their SARS-CoV-2 inhibitory and anti-inflammatory potentials
Moharram, F. A.-E., Ibrahim, R. R., Mahgoub, S., Abdel-aziz, M. S., Said, A. M., Huang, H., Chen, L.-Y., Lai, K.-H., Hashad, N., & Mady, M. S. (2025) · PLoS ONE · doi:10.1371/journal.pone.0313616 · Cited by 7
“…extreme increase in the circulating levels of pro-inflammatory cytokines including IL-1, IL-2, IL-6, IFN-γ , and TNF-α (a key role player in the cytokine storm), [22, 23], leading to ARDS (acute respiratory distress syndrome), intravascular coagulation, multiorgan failure and eventually death [24].”
COVID-19 and physical activity: What is the relation between exercise immunology and the current pandemic situation?
Azizi, G. G., Orsini, M. A., Dortas, S. D., Vieira, P. A. D. S., Carvalho, R. S. D., Pires, C. S. D. R., Silva, S. C. F. D., Pinto, B. M. D. S., Cardoso, C. E., Moreno, A. M., et al. (2020) · Revista Brasileira de Fisiologia do Exercício · doi:10.33233/rbfe.v19i2.4115 · Cited by 9
“Another report demonstrated increased cytokine levels (IL-6, IL-10, and TNF-α), lymphopenia (in CD4+ and CD8+ T cells), and decreased IFN-γ expression in CD4+ T cells are associated with severe COVID-19 [20].”
Background
Structural-based design of HD-TAC7 PROteolysis TArgeting chimeras (PROTACs) candidate transformations to abrogate SARS-CoV-2 infection
Zahid, S., Ali, Y., & Rashid, S. (2023) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2023.2183037 · Cited by 7
“…Biological Network, 2020; Jose & Manuel, 2020; Karki et al., 2021; Leoni et al., 2002; Mehta et al., 2020; Netea et al., 2016; Park & Iwasaki, 2020; Pedersen & Ho, 2020; Saeed et al., 2014; Takeuchi & Akira, 2010; Tisoncik et al., 2012; Villagra et al., 2010; Vincent, 2021; von Knethen & Br €…”
Background
COVID-19 Comes 40 Years After AIDS – Any Lesson?
de Mendoza, C., Bouza, J. M. E., Ramos, J. M., Barreiro, P., & Soriano, V. (2020) · Aids Reviews · doi:10.24875/aidsrev.m20000030 · Cited by 7
Blood Targets of Adjuvant Drugs Against COVID19
Micco, P. D., Micco, G. D., Russo, V., Poggiano, M. R., Salzano, C., Bosevski, M., Imparato, M., Fontanella, L., & Fontanella, A. (2020) · Journal of Blood Medicine · doi:10.2147/jbm.s256121 · Cited by 7
“Based on inflammatory origin, the cytokines’ storm involves mainly IL-1, IL-6, IFNγ, and IL-16.”
Background
Prolonged presence of SARS-CoV-2 in a COVID-19 case with rheumatoid arthritis taking iguratimod treated with ciclesonide
Baba, H., Kanamori, H., Oshima, K., Seike, I., Niitsuma-Sugaya, I., Takei, K., Sato, Y., Tokuda, K., & Aoyagi, T. (2020) · Journal of Infection and Chemotherapy · doi:10.1016/j.jiac.2020.06.022 · Cited by 7
“Overproduction of inflammatory cytokines such as interleukin (IL)-2, IL-6 and tumor necrosis factor (TNF)-a has been implicated in the deterioration of patients with COVID-19 [8,9].”
Tocilizumab for severe COVID-19 related illness – A community academic medical center experience
Meleveedu, K. S., Miskovsky, J., Meharg, J. V., Abdelrahman, A., Tandon, R., Moody, A. E., Dasilva, P., Masse, G., LaPorte, J. P., Calvino, A. S., et al. (2020) · Cytokine X · doi:10.1016/j.cytox.2020.100035 · Cited by 7
Pharmacotherapeutics of SARS-CoV-2 Infections
Kevadiya, B. D., Machhi, J., Herskovitz, J., Oleynikov, M. D., Blomberg, W. R., Bajwa, N., Soni, D., Das, S., Hasan, M., Patel, M., et al. (2021) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-020-09968-x · Cited by 6
Low levels of CIITA and high levels of SOCS1 predict COVID-19 disease severity in children and adults
Girona‐Alarcón, M., Argüello, G., Esteve‐Solé, A., Bobillo‐Pérez, S., Burgos-Artizzu, X. P., Bonet-Carné, E., Mensa‐Vilaró, A., Codina, A., Hernández, M., Jou, C., et al. (2021) · iScience · doi:10.1016/j.isci.2021.103595 · Cited by 7
“That is to say, the infection has been proven to cause an immune dysregulation with overproduction of pro-inflammatory cytokines (IL-1, IL-6, IL-2R, IL-10, and TNF-alpha) in severe cases (Chen et al., 2020; Ong et al., 2020; Pedersen and Ho, 2020).”
To protect or to kill: A persisting Darwinian immune dilemma
Besedovsky, H. O., & del Rey, A. (2022) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2022.04.019 · Cited by 8
Computing Basis and Dimension of Chloroquine and Hydroxychloroquine by Using Chemical Graph Theory
Singh, Y., Raza, H., Sharma, S. K., & Bhat, V. K. (2022) · Polycyclic aromatic compounds · doi:10.1080/10406638.2022.2086269 · Cited by 7
“Vertices rvðviÞ Vertices rvðviÞ v1 (0, 11) v12 (8, 3) v2 (1, 10) v13 (9, 4) v3 (2, 9) v14 (10, 5) v4 (3, 10) v15 (11, 4) v5 (4, 11) v16 (10, 3) v6 (3, 8) v17 (9, 2) v7 (4, 7) v18 (10, 1) v8 (5, 6) v19 (11, 0) v9 (6, 5) v20 (12, 1) v10 (7, 6) v21 (11, 2) v11 (7, 4) v22 (13, 2) 4136 Y.”
Long-Term Health Consequences of SARS-CoV-2: Assumptions Based on SARS-CoV-1 and MERS-CoV Infections
Khaswal, A., Kumar, V., & Kumar, S. (2022) · Diagnostics · doi:10.3390/diagnostics12081852 · Cited by 7
Evaluating immunohaematological profile among COVID-19 active infection and recovered patients in Ghana
Konlaan, Y., Sakyi, S. A., Asare, K. K., Barnie, P. A., Opoku, S., Nakotey, G. K., Nuvor, S. V., & Amoani, B. (2022) · PLoS ONE · doi:10.1371/journal.pone.0273969 · Cited by 7
Hematological ratios in coronavirus disease 2019 patients with and without invasive mechanical ventilation
Fernandes, N. F., Costa, I. F., Pereira, K. N., de Carvalho, J. A. M., & Paniz, C. (2023) · Journal of Investigative Medicine · doi:10.1177/10815589221149189 · Cited by 7
“In turn, SII is an inflammatory marker and has been used as a prognostic indicator in the follow-up of sepsis and in cancer patients.(14,15) Furthermore, SII has been studied as an aid in the diagnosis and prognosis of other diseases and currently also”
Method
Coronavirus disease 2019 information-seeking behavior globally: a systematic review
Anagaw, T. F., & Guadie, H. A. (2023) · SAGE Open Medicine · doi:10.1177/20503121231153510 · Cited by 10
“J Med Internet Res 2021; 23(1): e24097.”
Utility of laboratory and immune biomarkers in predicting disease progression and mortality among patients with moderate to severe COVID-19 disease at a Philippine tertiary hospital
Punzalan, F. E. R., Aherrera, J. A. M., de Paz‐Silava, S. L. M., Mondragon, A. V., Malundo, A. F. G., Tan, J. J. E., Tantengco, O. A. G., Quebral, E. P. B., Uy, M. N. A. R., Lintao, R. C. V., et al. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1123497 · Cited by 9
COVID-19: An Immunopathologic Assault
Munro, N., Scordo, K. A., & Richmond, M. M. (2020) · AACN Advanced Critical Care · doi:10.4037/aacnacc2020802 · Cited by 7
“Respiratory symptoms are common and usually begin 7 to 10 days after the onset of other general signs and symptoms (fever, cough, fatigue, myalgia), but presentation can vary.(12,13) Increasing IL-6 levels have been noted as well as lymphopenia, with low CD4+ and CD8+ T-cell counts.”
BackgroundInfluential
Gordian Knot: Gastrointestinal lesions caused by three highly pathogenic coronaviruses from SARS-CoV and MERS-CoV to SARS-CoV-2
Meng, X. L., Lou, Q., Yang, W.-Y., Chen, R., Xu, W.-H., Yang, Y., Zhang, L., Xu, T., & Xiang, H. (2020) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2020.173659 · Cited by 7
SARS-CoV-2 effects on male reproduction: should men be worried??
Farsimadan, M., & Motamedifar, M. (2021) · Human Fertility · doi:10.1080/14647273.2021.1962986 · Cited by 7
“Recent studies in patients with severe condition have shown higher levels of TNF-a, IL-6, and IL-1b to be playing significant roles in testicular function (McElvaney et al., 2020; Pedersen & Ho, 2020).”
Background
Hydroxychloroquine / azithromycin in COVID-19: The association between time to treatment and case fatality rate
Accinelli, R. A., Ynga-Meléndez, G. J., León-Abarca, J. A., López, L. M., Madrid-Cisneros, J. C., & Mendoza-Saldaña, J.-D. (2021) · Travel Medicine and Infectious Disease · doi:10.1016/j.tmaid.2021.102163 · Cited by 7
“Thus, in patients who present late after the onset of the infection, the use of antiviral agents alone will not suffice to stop the ensuing cytokine storm, lung destruction and respiratory distress [31].”
Periodically aperiodic pattern of SARS-CoV-2 mutations underpins the uncertainty of its origin and evolution
Hassan, S. S., Basu, P., Redwan, E. M. M. M., Lundstrom, K. H., Choudhury, P. P., Serrano‐Aroca, Á., Azad, G. K., Aljabali, A. A. A., Palù, G., El‐Aziz, T. M. A., et al. (2021) · Environmental Research · doi:10.1016/j.envres.2021.112092 · Cited by 7
“The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causative agent of the Coronavirus Disease (COVID-19) (Pedersen and Ho, 2020; Setti et al., 2020; Domingo et al., 2020).”
Yoga, immunity and COVID-19: A scoping review
Shah, K., Adhikari, C., Saha, S., & Saxena, D. (2022) · Journal of Family Medicine and Primary Care · doi:10.4103/jfmpc.jfmpc_2182_21 · Cited by 7
Handheld, Low-Cost, Aptamer-Based Sensing Device for Rapid SARS-CoV-2 RNA Detection Using Novelly Synthesized Gold Nanoparticles
Daniel, S. C. G. K., Pai, P. S., Sabbella, H., Singh, K., Rangaiah, A., Basawarajappa, S. G., & Thakur, C. S. (2022) · IEEE Sensors Journal · doi:10.1109/jsen.2022.3196598 · Cited by 7
“The prevalent symptoms that were observed in COVID-19 28 patients were fever, cough, sore throat, shortness of breath 29 or dyspnea, and severe cases leading to pneumonia [2], [3].”
Background
Inflammatory-Metal Profile as a Hallmark for COVID-19 Severity During Pregnancy
Vásquez-Procopio, J., Espejel-Núñez, A., Torres‐Torres, J., Martinez-Portilla, R. J., y Sosa, S. E., Mateu-Rogell, P., Ortega-Castillo, V., Tolentino‐Dolores, M., Perichart‐Perera, O., Franco-Gallardo, J. O., et al. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.935363 · Cited by 7
Alpha-1 adrenergic receptor antagonists to prevent hyperinflammation and death from lower respiratory tract infection.Preprint
Koenecke, A., Powell, M. A., Xiong, R., Shen, Z., Fischer, N. M., Huq, S., Khalafallah, A. M., Trevisan, M., Sparen, P., Carrero, J. J., et al. (2021) · PubMed · Cited by 9
Mesenchymal Stem Cells in the Treatment of New Coronavirus Pandemic: A Novel Promising Therapeutic Approach
Razi, S., Molavi, Z., Mirmotalebisohi, S. A., Niknam, Z., Sameni, M., Niazi, V., Adibi, A., Yazdani, M., Ranjbar, M. M., & Zali, H. (2021) · Advanced Pharmaceutical Bulletin · doi:10.34172/apb.2022.023 · Cited by 7
“49,50 Huang et al investigated the inflammatory factors and cytokine levels in patients with COVID-19.”
Background
Molecular characteristics and functional differentiation of two IL-10 genes in barbel chub Squaliobarbus curriculus
Yang, H., Qin, B., Fu, J., Zhang, M., Wang, H., Xiao, T., & Lv, Z. (2025) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2025.110514 · Cited by 6
Immunogenicity, efficacy, and safety of CoronaVac and Pfizer/BioNTech mRNA vaccines in patients with psoriasis receiving systemic therapies: A prospective cohort study
Ergun, T., Tekin, S. H., Sengün, O. A., Çakıcı, Ö. A., Seçkin, D., Adıay, C., Enül, H., Yilmaz, S., Ay, P., Haklar, G., et al. (2023) · Vaccine · doi:10.1016/j.vaccine.2023.05.052 · Cited by 7
“In patients with IMIDs, including psoriasis, there are concerns about the possibility of achieving attenuated vaccine-induced immune response due to either the underlying disease or the immune modifying medications being used by the patients [1,4].”
Birth of Catastrophe and Strange Attractors through Generalized Hopf Bifurcations in Covid-19 Transmission Mathematical Model
Wiraya, A., Adi, Y. A., Fitriana, L., Triyanto, T., Kusumadewi, Y. A., Safitri, A. N., & Nurmalitasari, A. (2024) · Chaos Theory and Applications · doi:10.51537/chaos.1448912 · Cited by 6
Deciphering the Complexities of Adult Human Steady State and Stress-Induced Hematopoiesis: Progress and Challenges
Watt, S. M., & Roubelakis, M. G. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26020671 · Cited by 7
Immunomodulatory Effects of Pentoxifylline: Profiling Data Based on RAW 264.7 Cellular Signaling
Seo, M. H., Eo, M. Y., Nguyen, T. T. H., Yang, H. J., & Kim, S. M. (2021) · Applied Sciences · doi:10.3390/app11178273 · Cited by 6
“[45] The severity of a cytokine storm and decreased T cells are associated with exacerbation of diseases such as pulmonary damage and respiratory distress [46,47].”
Background
Ramatroban for chemoprophylaxis and treatment of COVID-19: David takes on Goliath
Chiang, K. C., Rizk, J. G., Nelson, D. J., Krishnamurti, L., Subbian, S., Imig, J. D., Khan, I., Reddy, S. T., & Gupta, A. (2022) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2022.2031975 · Cited by 6
Aptamer-based Emerging Tools for Viral Biomarker Detection: A Focus on SARS-CoV-2
Kulabhusan, P. K., Pishva, P., Çapkın, E., Tambe, P., & Yüce, M. (2022) · Current Medicinal Chemistry · doi:10.2174/1568009622666220214101059 · Cited by 6
Detection of COVID-19 and Pneumonia Using Deep Convolutional Neural Network
Islam, M. S., Das, S. J., Khan, M. R. A., Momen, S., & Mohammed, N. (2022) · Computer Systems Science and Engineering · doi:10.32604/csse.2023.025282 · Cited by 6
Cannabidiol As a Treatment for COVID-19 Symptoms? A Critical Review
Holst, M., Nowak, D., & Hoch, E. (2022) · Cannabis and Cannabinoid Research · doi:10.1089/can.2021.0135 · Cited by 6
Fatal COVID-19 is Associated with Reduced HLA-DR, CD123 or CD11c Expression on Circulating Dendritic Cells
Hasan, A., Al‐Ozairi, E., Hassan, N. Y., Ali, S., Ahmad, R., Al-Shatti, N., Alshemmari, S., & Al‐Mulla, F. (2022) · Journal of Inflammation Research · doi:10.2147/jir.s360207 · Cited by 6
Pathological Changes in the Lungs of Patients with a Lethal COVID-19 Clinical Course
Viksne, V., Štrumfa, I., Sperga, M., Ziemelis, J., & Abolins, J. (2022) · Diagnostics · doi:10.3390/diagnostics12112808 · Cited by 6
“Furthermore, the mean CRP level was substantially increased, indicating a severe disease course in most patients, as this clinical parameter has been shown to correlate with disease severity in multiple studies [34,35].”
Result
Role of sphingosine 1-phosphate (S1P) in sepsis-associated intestinal injury
Sun, G., Wang, B., Zhu, H.-Q., Ye, J.-M., & Liu, X. (2023) · Frontiers in Medicine · doi:10.3389/fmed.2023.1265398 · Cited by 7
Role of micronutrients in the management of coronavirus disease 2019
AbdAllah, M., Ezelarab, H., Raslan, E., Saber, L. B., Daoud, E., & Saber, M. M. (2020) · New Microbes and New Infections · doi:10.1016/j.nmni.2020.100782 · Cited by 6
“Higher levels of interleukin-6, interleukin-10 and tumour necrosis factor-α are associated with poor outcome [3].”
Infusion of HLA-matched and static magnetic field-exposed allogenic lymphocytes treating lymphocytopenia and cytokine storm syndrome: A treatment proposal for COVID-19 patients
Vergallo, C. (2020) · Electromagnetic Biology and Medicine · doi:10.1080/15368378.2020.1830290 · Cited by 6
Update on treatment and preventive interventions against COVID-19: an overview of potential pharmacological agents and vaccines
Xiao, Y., Xu, H., Guo, W. Q., Zhao, Y., Luo, Y., Wang, M., He, Z., Ding, Z., Liu, J., Deng, L., et al. (2020) · Molecular Biomedicine · doi:10.1186/s43556-020-00017-w · Cited by 6
Coagulopathy in COVID-19
Lio, K. U., & Rali, P. M. (2020) · Lung India · doi:10.4103/lungindia.lungindia_226_20 · Cited by 6
“COVID‑19 Cytokine storm has been the most discussed theory explaining the varying disease severity in patients with COVID-19.”
BackgroundInfluential
Nanotechnology to the Rescue: Treatment Perspective for the Immune Dysregulation Observed in COVID-19
Peter, A. E., Sandeep, B. V., Rao, B. G., & Kalpana, V. L. (2021) · Frontiers in Nanotechnology · doi:10.3389/fnano.2021.644023 · Cited by 7
“1155/2014/939378 Svoboda, K. K., and Reenstra, W. R. (2002). Approaches to studying cellular signaling: a primer for morphologists.”
BackgroundInfluential
Immunogenicity and safety of SARS-CoV-2 vaccines in clinical trials
Lim, H. Y., Arip, M., Yahaya, A. A. A.-F. B., Jazayeri, S. D., Poppema, S., & Poh, C. L. (2021) · Frontiers in Bioscience-Landmark · doi:10.52586/5024 · Cited by 6
Evaluation of Neuropatic Pain Features in COVID-19 Patients
Ocak, Ö., & Şahi̇n, E. M. (2022) · Neurology India · doi:10.4103/0028-3886.344625 · Cited by 6
Putative Natural History of CoViD-19
Chiappelli, F. (2020) · Bioinformation · doi:10.6026/97320630016398 · Cited by 7
A 50-Year-Old Patient with Guillain–Barré Syndrome after COVID-19: A Case Report
Chmiela, T., Rzepka, M., Krzystanek, E., & Gorzkowska, A. (2021) · Medicina · doi:10.3390/medicina57080775 · Cited by 6
Markers of NETosis and DAMPs are altered in critically ill COVID-19 patientsPreprint
Huckriede, J., Anderberg, S. B., Morales, A., de Vries, F., Hultström, M., Bergqvist, A., Ortiz-Pérez, J. T., Sels, J.-W. E. M., Wichapong, K., Lipcsey, M., et al. (2020) · doi:10.21203/rs.3.rs-52432/v1 · Cited by 6
“List Of Abbreviations ACEi/ARB – angiotensin converting enzyme inhibitors/angiotensin-receptor blockers; ADAM – a disintegrin and metalloproteinase; ALI - acute lung injury; ALT – alanine transaminase; APTT - activated partial thromboplastin time; ARDS – acute respiratory distress syndrome; AST – aspartate aminotransf…”
Background
Perspectives on COVID-19 and cancer immunotherapy: a review series
Goldman, J. D., & Ascierto, P. A. (2021) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2021-002489 · Cited by 6
Clinical Relevance of Elevated Soluble ST2, HSP27 and 20S Proteasome in Patients with COVID-19Preprint
Wendt, R. T., Lingitz, M., Laggner, M., Mildner, M., Traxler, D., Graf, A. C., Krotka, P., Moser, B., Höetzenecker, K., Kalbitz, S., et al. (2021) · Preprints.org · doi:10.20944/preprints202108.0440.v1 · Cited by 6
“This finding supported the hypothesis that patients with severe COVID-19 exhibited strong inflammatory activation [5], [6], [8], and it confirmed previous findings that identified sST2 as a marker that clearly distinguished between patients with increased risk and patients with low risk of mortality [5], [6], [8], [38…”
Result
Spectrum of COVID-19 induced liver injury: A review report
Singh, L., Kumar, A., Rai, M., Basnet, B., Rai, N., Khanal, P., Lai, K., Cheng, W.-H., Asaad, A. M., & Ansari, S. (2024) · World Journal of Hepatology · doi:10.4254/wjh.v16.i4.517 · Cited by 5
Functional and structural investigation of a broadly neutralizing SARS-CoV-2 antibody
Chang, Y.-H., Hsu, M., Chen, W.-N., Wu, M., Kong, W., Lu, M. J., Huang, C.-H., Chang, F.-J., Chang, L., Tsai, H.-Y., et al. (2024) · JCI Insight · doi:10.1172/jci.insight.179726 · Cited by 5
Symmetrical peripheral gangrene: potential mechanisms and therapeutic approaches in severe COVID-19
Wang, M., Sun, T., Dong, L., Huang, S., & Liu, J. (2023) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2023.1280625 · Cited by 5
“Lymphopenia impairs the function of the immune system to produce antibodies against virus-speci ﬁ c antigens, as well as reducing the generation of interferon gamma (IFN-γ ) by the CD4+ T cells (43).”
Background
Zinc Deficiency And sTNF-RII Are Associated With Worse COVID-19 Outcomes
Mouchati, C., Durieux, J., Zisis, S. N., Tribout, H., Scott, S., Smith, B. A., Labbato, D. E., & McComsey, G. A. (2023) · Journal of Nutrition · doi:10.1016/j.tjnut.2023.11.026 · Cited by 6
Hydroxychloroquine attenuates double‐stranded RNA‐stimulated hyper‐phosphorylation of tristetraprolin/ZFP36 and AU‐rich mRNA stabilization
Hitti, E., Muazzen, Z., Moghrabi, W. N., Al‐Yahya, S., & Khabar, K. S. A. (2024) · Immunology · doi:10.1111/imm.13835 · Cited by 5
“Mortality in COVID-19 infections was often associated with excess inflammation and cytokine storm [6].”
Systemic immunobiological, immunosuppressant, and oncologic agents for the treatment of dermatologic diseases during the SARS‐CoV ‐2 ( COVID‐19 ) pandemic emergency: A quick review for a quick consultation
Paolino, G., Mercuri, S. R., Bearzi, P., & Mattozzi, C. (2020) · Dermatologic Therapy · doi:10.1111/dth.13537 · Cited by 4
“The immunologic response to SARS-CoV-2 infection, like many other viruses, is characterized by the robust production of proinflammatory cytokines.(3) Several cytokines are involved in the immune response against viral infections, such as interleukin (IL)-1β, IL-2, IL-7, IL-8, IL-9, IL-10, IL-17, G-CSF, granulocyte mac…”
Background
Diffuse interstitial pneumonia-like/macrophage activation syndrome-like changes in patients with COVID-19 correlate with length of illness
Felix, J. C., Sheinin, Y. M., Suster, D. I., Ronen, N., Ratiani, M., Heuvel, T. V., Winge, E., Patton, M. D., Rau, M. J., Ge, L., et al. (2021) · Annals of Diagnostic Pathology · doi:10.1016/j.anndiagpath.2021.151744 · Cited by 5
“It has been postulated that high levels of cytokines, such as IL6, IL10, and TNFα may be mediated by alveolar macrophages in these patients [11].”
Background
Cytokine-Induced Modulation of SARS-CoV2 Receptor Expression in Primary Human Nasal Epithelial Cells
Ramezanpour, M., Bolt, H., Hon, K., Bouras, G. S., Psaltis, A. J., Wormald, P., & Vreugde, S. (2021) · Pathogens · doi:10.3390/pathogens10070848 · Cited by 5
“However, a delayed and dysregulated response can evolve in some cases resulting in a cytokine storm which can be catastrophic to the patient [9].”
Background
COVID-19: well-known drugs, new opportunities
Uzbekistan’s Public Healthcare Ministry, 2. S. S., Хамидович, А. А., Мавлянов, И. Р., Искандарович, М. З., & Жарылкасынова, Г. Ж. (2020) · Health Risk Analysis · doi:10.21668/health.risk/2020.4.19 · Cited by 4
“Patients who are in critical state suffer from a drastic increase in contents of these factors, and IL-6 concentrations correlate with an increased in mortality [13, 14].”
Background
In silico approach for the development of novel antiviral compounds based on SARS-COV-2 protease inhibition
Ničkčović, V. P., Nikolić, G. R., Nedeljković, B. M., Mitić, N. R., Filipović-Danić, S., Mitić, J., Marčetić, Z., Sokolovic, D. T., & Veselinović, A. M. (2022) · Chemical Papers · doi:10.1007/s11696-022-02170-8 · Cited by 5
Psychiatric Manifestations of COVID-19: A Literature Review
Khatun, A., Tamilanban, T., & Chitra, V. (2022) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/1871527321666220701152821 · Cited by 5
Anti-inflammatory or anti-SARS-CoV-2 ingredients in Huashi Baidu Decoction and their corresponding targets: Target screening and molecular docking study
Wang, Z., & Gao, H. (2023) · Arabian Journal of Chemistry · doi:10.1016/j.arabjc.2023.104663 · Cited by 5
Intrauterine activation of the fetal immune system in response to maternal COVID-19
Gashimova, N. R., Pankratyeva, L. L., Bitsadze, V. O., Khizroeva, J. K., Makatsariya, N. А., Tretyakova, M. V., Shkoda, A. S., Grigoreva, K. N., Tsibizova, V. I., Gris, J., et al. (2023) · Obstetrics Gynecology and Reproduction · doi:10.17749/2313-7347/ob.gyn.rep.2023.404 · Cited by 5
Kinome and phosphoproteome reprogramming underlies the aberrant immune responses in critically ill COVID-19 patients
Kaneko, T., Ezra, S., Abdo, R., Voss, C., Zhong, S., liu, X., Hovey, O. F. J., Martin, C. M., Slessarev, M., Nynatten, L. R. V., et al. (2024) · Clinical Proteomics · doi:10.1186/s12014-024-09457-w · Cited by 5
“The cytokine release syndrome (CRS) or cytokine storm is a major cause of acute lung damage associated with log2 ratio between the patient group and HC patient mortality [47–52].”
Background
Enhancement of immune tolerance of COVID-19 patients might be achieved with alginate supplemented therapy
El-Sekaily, A., Helal, M., & Saad, A. A. (2020) · International Journal of Cancer and Biomedical Research · doi:10.21608/jcbr.2020.28938.1033 · Cited by 5
Seguridad y eficacia de ivermectina en tiempos de COVID-19
Universidad de San Martín de Porres, F. D. M., Cruz, A. P., Espino, J. C. L., & Universidad de San Martín de Porres, F. D. M. (2020) · Horizonte Médico (Lima) · doi:10.24265/horizmed.2021.v21n1.10 · Cited by 5
Laboratory tests for the detection of SARS-CoV-2 infection: basic principles and examples
Alkharsah, K. R. (2021) · PubMed Central · doi:10.3205/000293 · Cited by 5
“Lymphocytes may also be killed by apoptosis induced by several proinflammatory cytokines produced during the course of the disease such as tumor necrosis factor-alpha [18], [19].”
Background
Clinical, laboratory data and inflammatory biomarkers at baseline as early discharge predictors in hospitalized SARS-CoV-2 infected patients
Trujillo‐Rodríguez, M., Muñoz‐Muela, E., Serna‐Gallego, A., Praena‐Fernández, J. M., Pérez‐Gómez, A., Gasca‐Capote, C., Vitallé, J., Peraire, J., Palacios-Baena, Z. R., Cabrera, J. J., et al. (2022) · PLoS ONE · doi:10.1371/journal.pone.0269875 · Cited by 5
Host genetic variants associated with COVID-19 reconsidered in a Slovak cohort
Škereňová, M., Cibulka, M., Daňková, Z., Holubeková, V., Kolková, Z., Lučanský, V., Dvorská, D., Kapinová, A., Krivosova, M., Petráš, M., et al. (2024) · Advances in Medical Sciences · doi:10.1016/j.advms.2024.03.007 · Cited by 5
Mental illnesses among COVID-19 patients: Possible immunological underpinnings
Kar, S. K., Verma, P., Verma, S., & Saxena, S. K. (2020) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2020.102376 · Cited by 5
Local Anesthetics and Covid19 Associated Acute Respiratory Distress Syndrome: A New Therapeutic Indication?
Papathanasiou, G. S. (2020) · Clinical Research Open Access · doi:10.16966/2469-6714.156 · Cited by 5
Antivirals With Adjunctive Corticosteroids Prevent Clinical Progression of Early Coronavirus 2019 Pneumonia: A Retrospective Cohort Study
Ooi, S. T., Parthasarathy, P., Lin, Y., Nallakaruppan, V. D. O., Ng, S. J. H., Tan, T. C., Low, S. K., & Tang, T. (2020) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofaa486 · Cited by 5
“Severe COVID-19 is typically marked by rapid clinical deterioration with features of hyperinflammation [4, 5, 6].”
Background
Phenylmethimazole is a candidate drug for the treatment of severe forms of coronavirus disease 2019 (COVID-19) as well as other virus-induced “cytokines storm”
Giuliani, C., Bucci, I., & Napolitano, G. (2020) · Medical Hypotheses · doi:10.1016/j.mehy.2020.110473 · Cited by 5
Expression of SARS-CoV-2 Host Cell Entry Factors in Immune System Components of Healthy Individuals and Its Relevance for COVID-19 Immunopathology
Kumar, A., Kumar, S., Narayan, R. K., Kumari, C., Pareek, V., & Prasoon, P. (2021) · Viral Immunology · doi:10.1089/vim.2020.0277 · Cited by 5
“The COVID-19 severity is also characterized by differential response of immune cells: reﬂected by increased counts of neutrophils and macrophages, however, reduced counts of eosinophil and lymphocytes (speciﬁcally of CD4 + and CD8 + T cells) (12,13,19).”
Study correlating lymphocyte to monocyte ratio and platelet to lymphocyte ratio with the severity in COVID-19 patients: a cross sectional study
Prabhu, S., & Patil, N. (2021) · International Journal of Advances in Medicine · doi:10.18203/2349-3933.ijam20210264 · Cited by 5
Distinct Coagulopathy With Myocardial Injury and Pulmonary Embolism in COVID-19
Fath, A. R., Aglan, A. D., Varkoly, K., Eldaly, A. S., Beladi, R. N., Forlemu, A. N., Mihyawi, N., Solsi, A., Israr, S., & Lucas, A. R. (2021) · Journal of Investigative Medicine High Impact Case Reports · doi:10.1177/23247096211019559 · Cited by 5
The effectiveness of early colchicine administration in patients over 60 years old with high risk of developing severe pulmonary complications associated with coronavirus pneumonia SARS-CoV-2 (COVID-19): study protocol for an investigator-driven randomized controlled clinical trial in primary health care—COLCHICOVID study
Estebanez, E. B., Lavín-Alconero, L., Fernández, B. J., Marguello, M. G., Caro, J. C. L., Díez-Vallejo, J., Sampedro, M. F., Muñoz, P., Espiga, C. R., & García-Saiz, M. D. M. (2021) · Trials · doi:10.1186/s13063-021-05544-7 · Cited by 5
“Secondarily, the release of cytokines conditions the injury of the capillary alveolar membrane giving rise to respiratory distress [30] and favors a procoagulant state and hyperfibrinolysis characterized by an increase in D-dimer [32, 33].”
Quantitative measurement of activity of JAK-STAT signaling pathways in blood samples and immune cells to predict innate and adaptive cellular immune response to viral infection and accelerate vaccine developmentPreprint
Bouwman, W., Verhaegh, W., Holtzer, L., & van de Stolpe, A. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.05.13.092759 · Cited by 6
Fighting the storm: novel anti- TNFα and anti-IL-6 C. sativa lines to tame cytokine storm in COVID-19Preprint
Kovalchuk, A., Rodriguez‐Juarez, R., Ilnytskyy, S., Li, D., Wang, B., Kovalchuk, I., & Kovalchuk, O. (2020) · doi:10.21203/rs.3.rs-30927/v1 · Cited by 5
LOX-1 + immature neutrophils predict severe COVID-19 patients at risk of thrombotic complicationsPreprint
Combadière, B., Adam, L., Quentric, P., Rosenbaum, P., Dorgham, K., Bonduelle, O., Parizot, C., Sauce, D., Mayaux, J., Luyt, C. E., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.09.15.293100 · Cited by 5
Heart failure and COVID-19: synergism of two inflammatory conditions?
Khan, E. (2020) · British Journal of Community Nursing · doi:10.12968/bjcn.2021.26.1.18 · Cited by 4
Potencial Rol de la Periodontitis en la Severidad de COVID-19. Revisión
Hernández-Vigueras, S., & Aquino-Martinez, R. (2021) · International journal of odontostomatology · doi:10.4067/s0718-381x2021000200335 · Cited by 2
Association between Guillain-Barré syndrome and COVID-19 infection: Experience of a Turkish neurophysiology laboratory
Gümüşyayla, Ş., Durmaz, Ş. E., & Kaya, B. U. (2022) · Nöro Psikiyatri Arşivi · doi:10.29399/npa.27855 · Cited by 4
Molecular mechanisms implicated in SARS-CoV-2 liver tropism
Quarleri, J. F., & Delpino, M. V. (2022) · World Journal of Gastroenterology · doi:10.3748/wjg.v28.i48.6875 · Cited by 4
Penetration of Cell Surface Glycocalyx by Enveloped Viruses Is Aided by Weak Multivalent Adhesive Interaction
Cui, X., Zhang, X. F., & Jagota, A. (2023) · The Journal of Physical Chemistry B · doi:10.1021/acs.jpcb.2c06662 · Cited by 4
2-Deoxy-d-Glucose: A Repurposed Drug for COVID-19 Treatment
Chopra, S., Dahiya, A., Nair, A., Sharma, N., & Sharma, R. K. (2023) · Springer eBooks · doi:10.1007/978-981-19-5399-6_20 · Cited by 4
Severe COVID-19: Drugs and Clinical Trials
Ceja-Gálvez, H. R., Renteria-Flores, F. I., Nicoletti, F., Hernández‐Bello, J., Ojeda, G. M., & Muñóz-Valle, J. F. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12082893 · Cited by 5
“Dysregulation of T-cell functions precedes the cytokine storm (uncontrolled immune response) and neutrophil expansion in alveolar tissues, leading to tissue damage [162].”
Background
Association of Coagulopathy and Inflammatory Biomarkers with Severity in SARS-CoV-2-Infected Individuals of the Al-Qunfudhah Region of Saudi Arabia
Izhari, M. A., Hadadi, M. A. A., Alharbi, R., Gosady, A. R. A., Sindi, A. A. A., Dardari, D. M. M., Alotaibi, F. E., Klufah, F., Albanghali, M. A., & Alharbi, T. H. (2024) · Healthcare · doi:10.3390/healthcare12070729 · Cited by 4
“Cytokine response storm with elevated inflammatory serological biomarkers and coagulopathy worsen outcomes in COVID-19-infected individuals [6,7].”
Background
Elevated levels of pro-thrombotic eNOS-negative platelets in COVID-19 patients
Asgari, A., Franczak, A., Herchen, A., Jickling, G. C., & Jurasz, P. (2024) · Thrombosis Research · doi:10.1016/j.thromres.2024.109178 · Cited by 4
Neuropsychiatric disorders in the course to SARS-CoV-2 virus infection, including biological pathomechanisms, psychosocial factors and long COVID-19 associated with “brain fog”
Sadowski, J., Ostrowska, S. A., Klaudel, T., Zaborska, M., Chruszcz, M., Sztangreciak-Lehun, A., & Bułdak, R. J. (2025) · Journal of NeuroVirology · doi:10.1007/s13365-025-01242-1 · Cited by 4
“The main cells involved in the response to infection are T lymphocytes, B lymphocytes, neutrophils, and other antigen-presenting cells, of which macrophages play the main role (Kempuraj et al. 2020a; Pedersen and Ho 2020).”
Cytokine levels and pathological characteristics of a patient with severe coronavirus disease 2019: a case report
Kang, K., Gao, Y., Zhao, M., Fei, D., Ye, M., Gao, Y., Yang, W. Z., Wang, C., Liu, H., Chang, G.-P., et al. (2021) · Chinese Medical Journal · doi:10.1097/cm9.0000000000001540 · Cited by 4
Surveillance of hemorrhagic fever and/or neuroinvasive disease: challenges of diagnosis
de Araújo, L. J. T., Gonzalez, L. L., Buss, L., Guerra, J. M., Gomez, D. S., Ferreira, C. S. D. S., Cirqueira, C. D. S., Ghillardi, F., Witkin, S. S., & Sabino, É. C. (2021) · Revista de Saúde Pública · doi:10.11606/s1518-8787.2021055003068 · Cited by 4
“Dengue, (1034) 968 (94) 730 (71) 334 (32) 555 (54) 352 (34) 112 (11) 46 (4) 21 (2) Leptospirosis, (633) 572 (90) 606 (96) 258 (41) 415 (66) 262 (41) 79 (12) 32 (5) 9 (1) Yellow fever, (398) 250 (63) 249 (63) 374 (94) 228 (57) 154 (39) 37 (9) 37 (9) 16 (4) Rickettsia, (382) 348 (91) 342 (90) 194 (51) 349 (91) 193 (51)…”
COVID-19 & Sociocultural Determinants of Global Sanitation: An Aide-Mémoire and Call to Decolonize Global Sanitation Research & Practice
Irfan, A., & Jean, D. T. S. (2021) · Annals of Global Health · doi:10.5334/aogh.3358 · Cited by 7
Does COVID-19 Affect Adult Neurogenesis? A Neurochemical Perspective
Saikarthik, J., Saraswathi, I., & Al-Atram, A. A. (2021) · IntechOpen eBooks · doi:10.5772/intechopen.101179 · Cited by 4
“Increased levels of IL-6 correlate with mortality and the need for ventilator support [105, 106].”
Background
TNF-α Levels in Respiratory Samples Are Associated with SARS-CoV-2 Infection
Pereson, M. J., Badano, M. N., Aloisi, N., Chuit, R., de Bracco, M. M. E., & Baré, P. (2022) · Microbiology Spectrum · doi:10.1128/spectrum.01411-21 · Cited by 4

Authors: Pedersen, S. F., & Ho, Y.-C.
Affiliations: Yale University (US)
Corresponding author: Ho, Ya-Chi
ORCID: Ho, Ya-Chi
Venue: Journal of Clinical Investigation
Publisher: American Society for Clinical Investigation
Published: 2020-04-13
Volume: 130
Issue: 5
Pages: 2202-2205
ISSN: 0021-9738 (ISSN-L)
1558-8238
DOI: 10.1172/jci137647
PMC: PMC7190904
OpenAlex: W3014001472
Cited by: 1,137
References: 23
Citations by year: 2026: 11 · 2025: 34 · 2024: 60 · 2023: 113 · 2022: 183 · 2021: 341 · 2020: 395
FWCI: 33.90
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Journal of Clinical Investigation (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: amfAR, The Foundation for AIDS Research
Yale University
Gilead Sciences
National Institutes of Health (AI150464, DA047037, UL1TR001863)
National Institute on Drug Abuse (R61DA047037)
National Institute of Allergy and Infectious Diseases (UM1AI126620, P50AI150464, R01AI047868, R01AI141009, R37AI147868)
National Center for Advancing Translational Sciences
Topics: Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
Physical Sciences › Mathematics › Modeling and Simulation › COVID-19 epidemiological studies
Keywords: SARS-CoV-2, COVID-19 pandemic, pandemic, Betacoronavirus, airborne transmission, fomite transmission, pre-symptomatic transmission, undetected infections, WHO pandemic declaration
MeSH terms: Betacoronavirus, COVID-19, SARS-CoV-2, Age Factors, Humans, Lymphocytes, Pneumonia, Viral, Respiratory Distress Syndrome, Severity of Illness Index, Cytokines, Coronavirus Infections, Disease Progression, Pandemics

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

SARS-CoV-2: a storm is raging

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks