Obesity is associated with macrophage accumulation in adipose tissue

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1. Release of Inflammatory Mediators by Human Adipose Tissue Is Enhanced in Obesity and Primarily by the Nonfat Cells: A Review
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2. Identification of an Adipogenic Niche for Adipose Tissue Remodeling and Restoration
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3. MECHANISMS IN ENDOCRINOLOGY: White, brown and pink adipocytes: the extraordinary plasticity of the adipose organ
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4. Macrophage-Secreted Factors Promote a Profibrotic Phenotype in Human Preadipocytes
   Mayoura Kéophiphath, Vincent Achard, Corneliu Hénégar, Christine Rouault, Karine Clément, Danièle Lacasa · 2008 · Molecular Endocrinology
5. In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue
   Nishimura, Satoshi, Manabe, Ichiro, Nagasaki, Mika, Seo, Kinya, Yamashita, Hiroshi, Hosoya, Yumiko, Ohsugi, Mitsuru, Tobe, Kazuyuki, Kadowaki, Takashi, Nagai, Ryozo et al. · 2008 · Journal of Clinical Investigation
6. Activins and Inhibins: Roles in Development, Physiology, and Disease
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7. The kynurenine pathway is activated in human obesity and shifted toward kynurenine monooxygenase activation
   M. Favennec, B. Hennart, R. Caiazzo, A. Leloire, L. Yengo, M. Verbanck, A. Arredouani, M. Marre, M. Pigeyre, A. Bessède et al. · 2015 · Obesity
8. Macrophage Polarization in Obesity and Type 2 Diabetes: Weighing Down Our Understanding of Macrophage Function?
   Michael James Kraakman, Andrew James Murphy, Karin Agnes Maria Jandeleit-Dahm, Hélène L. Kammoun · 2014 · Frontiers in Immunology
9. TNF Counterbalances the Emergence of M2 Tumor Macrophages
   Franz Kratochvill, Geoffrey A. M. Neale, Jessica M. Haverkamp, Lee-Ann Van de Velde, Amber M. Smith, Daisuke Kawauchi, Justina D. McEvoy, Martine F. Roussel, Michael A. Dyer, Joseph E. Qualls et al. · 2015 · Cell Reports
10. IBD immunopathogenesis: A comprehensive review of inflammatory molecules
    Jae Hyon Park, Laurent Peyrin‐Biroulet, Michael Eisenhut, Jae Il Shin · 2017 · Autoimmunity Reviews
11. Resident and Monocyte-Derived Macrophages in Cardiovascular Disease
    Lisa Honold, Matthias Nahrendorf · 2018 · Circulation Research
12. Deciphering the cellular interplays underlying obesity-induced adipose tissue fibrosis
    Geneviève Marcelin, Ana Letícia Malheiros Silveira, Laís Bhering Martins, Adaliene Versiani Matos Ferreira, Karine Clément · 2019 · Journal of Clinical Investigation
13. Adipokines in obesity
    Viviane de Oliveira Leal, Denise Mafra · 2013 · Clinica Chimica Acta
14. Fatty acid—induced inflammation and insulin resistance in skeletal muscle and liver
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15. Current Concept and Update of the Macrophage Plasticity Concept: Intracellular Mechanisms of Reprogramming and M3 Macrophage “Switch” Phenotype
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16. Insulin signalling mechanisms for triacylglycerol storage
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17. The inflammatory consequences of psychologic stress: Relationship to insulin resistance, obesity, atherosclerosis and diabetes mellitus, type II
    Paul H. Black · 2006 · Medical Hypotheses
18. Adipocyte Lipid Chaperone aP2 Is a Secreted Adipokine Regulating Hepatic Glucose Production
    Haiming Cao, Motohiro Sekiya, Meric Erikci Ertunc, Mehmet Furkan Burak, Jared R. Mayers, Ariel White, Karen Inouye, Lisa Rickey, Barış Erçal, Masato Furuhashi et al. · 2013 · Cell Metabolism
19. Retinol-Binding Protein 4 Inhibits Insulin Signaling in Adipocytes by Inducing Proinflammatory Cytokines in Macrophages through a c-Jun N-Terminal Kinase- and Toll-Like Receptor 4-Dependent and Retinol-Independent Mechanism
    Julie Norseen, Tetsuya Hosooka, Ann Hammarstedt, Mark M. Yore, Shashi Kant, Pratik Aryal, Urban A. Kiernan, David Alan Phillips, Hiroshi Maruyama, Bettina Johanna Kraus et al. · 2012 · Molecular and Cellular Biology
20. Role of immune cells in obesity induced low grade inflammation and insulin resistance
    Ambreen Asghar, Nadeem Sheikh · 2017 · Cellular Immunology
21. Mechanistic Links Between Obesity, Diabetes, and Blood Pressure: Role of Perivascular Adipose Tissue
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22. Leptin as a key regulator of the adipose organ
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23. Obesity and asthma
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24. The Role of Gut Microbiota on Insulin Resistance
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25. Meta-Inflammation and Metabolic Reprogramming of Macrophages in Diabetes and Obesity: The Importance of Metabolites
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26. Interleukin-6 depletion selectively improves hepatic insulin action in obesity.
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27. The adipocyte as an endocrine organ in the regulation of metabolic homeostasis
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28. Obesity and cancer: existing and new hypotheses for a causal connection
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29. Regulation of obesity and insulin resistance by nitric oxide
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30. Heme Oxygenase-1 Drives Metaflammation and Insulin Resistance in Mouse and Man
    Alexander Jaïs, Elisa Einwallner, Omar Sharif, Klaus Gossens, Tess Tsai-Hsiu Lu, Selma M. Soyal, Dávid Medgyesi, Daniel Neureiter, Jamile Paier-Pourani, Kevin Dalgaard et al. · 2014 · Cell
31. Macrophage polarization: the link between inflammation and related diseases
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32. Lactobacillus acidophilus ameliorates obesity in mice through modulation of gut microbiota dysbiosis and intestinal permeability
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33. Maternal High-Fat Diet Disturbs Uteroplacental Hemodynamics and Increases the Frequency of Stillbirth in a Nonhuman Primate Model of Excess Nutrition
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34. Targeting the gut microbiome to treat the osteoarthritis of obesity
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35. Macrophages, Chronic Inflammation, and Insulin Resistance
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36. Magnesium, inflammation, and obesity in chronic disease
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37. Inhibition of Notch signaling promotes browning of white adipose tissue and ameliorates obesity
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38. Microarray profiling of isolated abdominal subcutaneous adipocytes from obese vs non-obese Pima Indians: increased expression of inflammation-related genes
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39. Rosiglitazone promotes development of a novel adipocyte population from bone marrow–derived circulating progenitor cells
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40. Mechanical Stimulation of Mesenchymal Stem Cell Proliferation and Differentiation Promotes Osteogenesis While Preventing Dietary-Induced Obesity
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41. Adipocyte-Macrophage Cross-Talk in Obesity
    Ayşe Başak Engin · 2017 · Advances in experimental medicine and biology
42. Fat in the liver and insulin resistance
    Hannele Yki‐Järvinen · 2005 · Annals of Medicine
43. Oversecretion of interleukin-15 from skeletal muscle reduces adiposity
    Quinn, LeBris S., Anderson, Barbara G., Strait-Bodey, Lena, Stroud, Ashley M., Argilés, Josép M. · 2009 · American Journal of Physiology-Endocrinology and Metabolism
44. Probiotics modulate gut microbiota and improve insulin sensitivity in DIO mice
    Bagarolli, Renata A., Tobar, Natália, Oliveira, Alexandre G., Araújo, Tiago G., Carvalho, Bruno M., Rocha, Guilherme Z., Vecina, Juliana F., Calisto, Kelly, Guadagnini, Dioze, Prada, Patrícia O. et al. · 2017 · The Journal of Nutritional Biochemistry
45. Visceral fat and metabolic inflammation: the portal theory revisited
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46. Adipose Tissue Remodeling under Ischemia: Death of Adipocytes and Activation of Stem/Progenitor Cells
    Hirotaka Suga, Hitomi Eto, Noriyuki Aoi, Harunosuke Kato M. D, Jun Araki, Kentaro Doi, Takuya Higashino, Kotaro Yoshimura · 2010 · Plastic & Reconstructive Surgery
47. Adipocyte NCoR Knockout Decreases PPARγ Phosphorylation and Enhances PPARγ Activity and Insulin Sensitivity
    Pingping Li, WuQiang Fan, Jianfeng Xu, Min M. Lu, Hiroyasu Yamamoto, Johan H. Auwerx, Dorothy D. Sears, Saswata Talukdar, Dayoung Oh, Ai Chen et al. · 2011 · Cell
48. Perivascular adipose tissue: More than just structural support
    Szasz, Theodora, Webb, R. Clinton · 2012 · Clinical Science
49. Obesity Promotes Breast Cancer by CCL2-Mediated Macrophage Recruitment and Angiogenesis
    Lisa M. Arendt, Jessica McCready, Patricia J. Keller, Dana D. Baker, Stephen P. Naber, Victoria L. Seewaldt, Charlotte Kuperwasser · 2013 · Cancer Research
50. Resolvin D1 and Resolvin D2 Govern Local Inflammatory Tone in Obese Fat
    Joan Clària, Jesmond Dalli, Stephanie Yacoubian, Fei Gao, Charles Nicholas Serhan · 2012 · The Journal of Immunology
51. Pathogenesis and management issues for non-alcoholic fatty liver disease
    Marko Duvnjak · 2007 · World Journal of Gastroenterology
52. Vitamin D deficiency and diabetes
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53. Nutrition, inflammation and liver-spleen axis
    Luigi Barrea, Carolina Di Somma, Giovanna Muscogiuri, Giovanni Tarantino, Gian Carlo Tenore, Francesco Orio, Annamaria Colao, Silvia Savastano · 2017 · Critical Reviews in Food Science and Nutrition
54. Glutamine Links Obesity to Inflammation in Human White Adipose Tissue
    Petrus, Paul, Lecoutre, Simon, Dollet, Lucile, Wiel, Clotilde, Sulen, André, Gao, Hui, Tavira, Beatriz, Laurencikiene, Jurga, Rooyackers, Olav, Checa, Antonio et al. · 2020 · Cell Metabolism
55. From cytokine to myokine: The emerging role of interleukin-6 in metabolic regulation
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56. Complex Actions of Sex Steroids in Adipose Tissue, the Cardiovascular System, and Brain: Insights from Basic Science and Clinical Studies
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57. Adipokine inflammation and insulin resistance: the role of glucose, lipids and endotoxin
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58. Invited review: The influence of immune activation on transition cow health and performance—A critical evaluation of traditional dogmas
    E.A. Horst, S.K. Kvidera, Lance H. Baumgard · 2021 · Journal of Dairy Science
59. Neutrophil Activation in Morbid Obesity, Chronic Activation of Acute Inflammation
    Jeroen Nijhuis, Sander S. Rensen, Yanti Slaats, François M. H. van Dielen, Wim A. Buurman, J.W.M. Greve · 2009 · Obesity
60. Chronic Inflammation Links Cardiovascular, Metabolic and Renal Diseases
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61. The Obesity Pandemic: Where Have We Been and Where Are We Going?
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62. Role of gut microflora in the development of obesity and insulin resistance following high-fat diet feeding
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63. Associations of Adiponectin, Resistin, and Tumor Necrosis Factor-α with Insulin Resistance
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64. Role of macrophage tissue infiltration in metabolic diseases
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65. Adipose tissue inflammation: a cause or consequence of obesity-related insulin resistance?
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66. Blocking IL-6 trans-signaling prevents high-fat diet-induced adipose tissue macrophage recruitment but does not improve insulin resistance
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67. Cytokines Promote Wnt Signaling and Inflammation and Impair the Normal Differentiation and Lipid Accumulation in 3T3-L1 Preadipocytes
    Birgit Gustafson, Ulf Smith · 2006 · Journal of Biological Chemistry
68. Fat as an Endocrine Organ: Relationship to the Metabolic Syndrome
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69. The correlation between adiposity and adiponectin, tumor necrosis factor α, interleukin-6 and high sensitivity C-reactive protein levels. Is adipocyte size associated with inflammation in adults?
    Mithat Bahçeci, Deniz Gökalp, Selen Bahçeci, Alparslan Kemal Tuzcu, Selahattin Atmaca, S. Arikan · 2007 · Journal of Endocrinological Investigation
70. Curcumin and resveratrol inhibit nuclear factor-kappaB-mediated cytokine expression in adipocytes
    Amanda M. Gonzales, Robert A. Orlando · 2008 · Nutrition & Metabolism
71. Inflammation as a Therapeutic Target for Diabetic Neuropathies
    Rodica Pop‐Busui, Lynn P. Ang, Crystal Holmes, Katherine Ann Gallagher, Eva L. Feldman · 2016 · Current Diabetes Reports
72. Adipose tissue macrophages: phenotypic plasticity and diversity in lean and obese states
    David Lee Morris, Kanakadurga Singer, Carey Nien-Kai Lumeng · 2011 · Current Opinion in Clinical Nutrition & Metabolic Care
73. The role of cadmium in obesity and diabetes
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74. Behavioural treatments for chronic systemic inflammation: effects of dietary weight loss and exercise training
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75. A systematic review of natural products for skin applications: Targeting inflammation, wound healing, and photo-aging
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76. Chronic intermittent hypoxia is a major trigger for non-alcoholic fatty liver disease in morbid obese
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77. Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity
    Bhama Ramkhelawon, Elizabeth J. Hennessy, Mickaël Mathieu Ménager, Tathagat Dutta Ray, Frederick J. Sheedy, Susan B. Hutchison, Amarylis Claudine Bonito Azeredo Wanschel, Scott R. Oldebeken, Michèle Geoffrion, Westley Spiro et al. · 2014 · Nature Medicine
78. Macrophage/cancer cell interactions mediate hormone resistance by a nuclear receptor derepression pathway.
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79. Metabolic disturbances in non-alcoholic fatty liver disease
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80. The adipocyte as an active participant in energy balance and metabolism
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81. FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages
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82. Role of Adipose Tissue as an Inflammatory Organ in Human Diseases
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83. Lipid-Overloaded Enlarged Adipocytes Provoke Insulin Resistance Independent of Inflammation
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84. Reactive oxygen species and insulin resistance: the good, the bad and the ugly
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85. The Inflammation and Liver Cancer
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86. Gut microbiota and diabetes: from pathogenesis to therapeutic perspective
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87. Kupffer cell activation is a causal factor for hepatic insulin resistance
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88. Association Between Elevated Liver Enzymes and C-Reactive Protein
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89. The clinical potential of circulating microRNAs in obesity
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90. Macrophage function in adipose tissue homeostasis and metabolic inflammation
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91. Mechanisms of macrophage activation in obesity-induced insulin resistance
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92. Obesity-Initiated Metabolic Syndrome and the Kidney
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93. Obesity-induced DNA released from adipocytes stimulates chronic adipose tissue inflammation and insulin resistance
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94. Adipocyte biology in breast cancer: From silent bystander to active facilitator
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95. Exercise training versus diet-induced weight-loss on metabolic risk factors and inflammatory markers in obese subjects: a 12-week randomized intervention study
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96. Apoptosis in nonalcoholic fatty liver disease: diagnostic and therapeutic implications
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97. Omentin: A Novel Link Between Inflammation, Diabesity, and Cardiovascular Disease
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98. Different effects of adiponectin isoforms in human monocytic cells
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99. Relation of C-Reactive Protein to Abdominal Adiposity
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100. The Relationship Between Gut Microbiota and Inflammatory Diseases: The Role of Macrophages
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