Inhaled NO accelerates restoration of liver function in adults following orthotopic liver transplantation

Enzyme-independent formation of nitric oxide in biological tissues

Zweier, J. L., Wang, P., Samouilov, A., & Kuppusamy, P. (1995) · Nature Medicine · doi:10.1038/nm0895-804 · Cited by 788

The role of oxidants and free radicals in reperfusion injury

Zweier, J. L., & Talukder, M. F. (2006) · Cardiovascular Research · doi:10.1016/j.cardiores.2006.02.025 · Cited by 743

Nitrate, bacteria and human health

Lundberg, J. O., Weitzberg, E., Cole, J. A., & Benjamin, N. (2004) · Nature Reviews Microbiology · doi:10.1038/nrmicro929 · Cited by 739

Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver

Duranski, M. R., Greer, J. J. M., Dejam, A., Jaganmohan, S., Hogg, N., Langston, W., Patel, R. P., Yet, S.-F., Wang, X., Kevil, C. G., et al. (2005) · Journal of Clinical Investigation · doi:10.1172/jci22493 · Cited by 674

The emerging biology of the nitrite anion

Gladwin, M. T., Schechter, A. N., Kim-Shapiro, D. B., Patel, R. P., Hogg, N., Shiva, S., Cannon, R. O., Kelm, M., Wink, D. A., Espey, M. G., et al. (2005) · Nature Chemical Biology · doi:10.1038/nchembio1105-308 · Cited by 609

Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia–reperfusion damage

Webb, A., Bond, R., McLean, P., Uppal, R., Benjamin, N., & Ahluwalia, A. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402927101 · Cited by 608

Nitrite is a signaling molecule and regulator of gene expression in mammalian tissues

Bryan, N. S., Fernandez, B. O., Bauer, S. M., Garcia-Saura, M. F., Milsom, A. B., Rassaf, T., Maloney, R. E., Bharti, A., Rodriguez, J., & Feelisch, M. (2005) · Nature Chemical Biology · doi:10.1038/nchembio734 · Cited by 518

Nitric oxide in the human respiratory cycle

McMahon, T., Moon, R. E., Luschinger, B. P., Carraway, M. S., Stone, A. E., Stolp, B. W., Gow, A. J., Pawloski, J. R., Watke, P., Singel, D. J., et al. (2002) · Nature Medicine · doi:10.1038/nm718 · Cited by 462

Hepatic ischemia/reperfusion injury—a fresh look

Fondevila, C., Busuttil, R. W., & Kupiec‐Weglinski, J. W. (2003) · Experimental and Molecular Pathology · doi:10.1016/s0014-4800(03)00008-x · Cited by 407

Cellular targets and mechanisms of nitros(yl)ation: An insight into their nature and kinetics in vivo

Bryan, N. S., Rassaf, T., Maloney, R. E., Rodriguez, C. M., Saijo, F., Rodriguez, J. R., & Feelisch, M. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0306706101 · Cited by 400

Ischemia and reperfusion—from mechanism to translation

Eltzschig, H. K., & Eckle, T. D. L. G. (2011) · Nature Medicine · doi:10.1038/nm.2507 · Cited by 3,468

The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics

Lundberg, J. O., Weitzberg, E., & Gladwin, M. T. (2008) · Nature Reviews Drug Discovery · doi:10.1038/nrd2466 · Cited by 2,739

Ischaemia–reperfusion injury in liver transplantation—from bench to bedside

Zhai, Y., Petrowsky, H., Hong, J. C., Busuttil, R. W., & Kupiec‐Weglinski, J. W. (2012) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2012.225 · Cited by 848

Strategies to increase nitric oxide signalling in cardiovascular disease

Lundberg, J. O., Gladwin, M. T., & Weitzberg, E. (2015) · Nature Reviews Drug Discovery · doi:10.1038/nrd4623 · Cited by 576

Nitrite as Regulator of Hypoxic Signaling in Mammalian Physiology

van Faassen, E. E., Bahrami, S., Feelisch, M., Hogg, N., Kelm, M., Kim‐Shapiro, D. B., Kozlov, A. V., Li, H., Lundberg, J. O., Mason, R., et al. (2009) · Medicinal Research Reviews · doi:10.1002/med.20151 · Cited by 435

Mitochondrial dysfunction and oxidative stress in the pathogenesis of alcohol- and obesity-induced fatty liver diseases

Mantena, S. K., King, A. L., Andringa, K. K., Eccleston, H. B., & Bailey, S. M. (2008) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.12.029 · Cited by 429

Update on ischemia-reperfusion injury in kidney transplantation: Pathogenesis and treatment

Salvadori, M., Rosso, G., & Bertoni, E. (2015) · World Journal of Transplantation · doi:10.5500/wjt.v5.i2.52 · Cited by 392

Hepatic ischemia reperfusion injury: A systematic review of literature and the role of current drugs and biomarkers

Cannistrà, M., Ruggiero, M., Zullo, A., Gallelli, G., Serafini, S., Mazzitelli, M., Naso, A., Grande, R., Serra, R., & Nardo, B. (2016) · International Journal of Surgery · doi:10.1016/j.ijsu.2016.05.050 · Cited by 390

Practical Recommendations for Long-term Management of Modifiable Risks in Kidney and Liver Transplant Recipients

Neuberger, J., Bechstein, W. O., Kuypers, D. R. J., Burra, P., Citterio, F., Geest, S. D., Duvoux, C., Jardine, A. G., Kamar, N., Krämer, B. K., et al. (2017) · Transplantation · doi:10.1097/tp.0000000000001651 · Cited by 327

Nitric oxide in liver diseases

Iwakiri, Y., & Kim, M. Y. (2015) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2015.05.001 · Cited by 312

Liver transplantation: past, present and future

Zarrinpar, A., & Busuttil, R. W. (2013) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2013.88 · Cited by 299

The functional nitrite reductase activity of the heme-globins

Gladwin, M. T., & Kim-Shapiro, D. B. (2008) · Blood · doi:10.1182/blood-2008-01-115261 · Cited by 293

Postreperfusion syndrome during liver transplantation for cirrhosis: Outcome and predictors

Paugam‐Burtz, C., Kavafyan, J., Merckx, P., Dahmani, S., Sommacale, D., Ramsay, M. A. E., Belghiti, J., & Mantz, J. (2009) · Liver Transplantation · doi:10.1002/lt.21730 · Cited by 249

The Noncanonical Pathway for In Vivo Nitric Oxide Generation: The Nitrate-Nitrite-Nitric Oxide Pathway

Kapil, V., Khambata, R. S., Jones, D. A., Rathod, K., Primus, C., Massimo, G., Fukuto, J. M., & Ahluwalia, A. (2020) · Pharmacological Reviews · doi:10.1124/pr.120.019240 · Cited by 248

Nitric Oxide for Inhalation in the Acute Treatment of Sickle Cell Pain Crisis

Gladwin, M. T. (2011) · JAMA · doi:10.1001/jama.2011.235 · Cited by 223

Major Challenges Limiting Liver Transplantation in the United States

Wertheim, J. A., Petrowsky, H., Saab, S., Kupiec‐Weglinski, J. W., & Busuttil, R. W. (2011) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2011.03587.x · Cited by 188

Nitric Oxide Mechanism of Protection in Ischemia and Reperfusion Injury

Phillips, L., Toledo, A. H., López-Neblina, F., Anaya‐Prado, R., & Toledo-Pereyra, L. H. (2009) · Journal of Investigative Surgery · doi:10.1080/08941930802709470 · Cited by 193

Chronic sodium nitrite therapy augments ischemia-induced angiogenesis and arteriogenesis

Kumar, D., Branch, B. G., Pattillo, C. B., Hood, J., Thoma, S., Simpson, S., Illum, S., Arora, N., Chidlow, J. H., Langston, W., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0711480105 · Cited by 187

NO-synthase independent NO generation in mammals

Lundberg, J. O., & Weitzberg, E. (2010) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2010.02.136 · Cited by 175

Molecular Mediators of Liver Ischemia and Reperfusion Injury: A Brief Review

Vardanian, A. J., Busuttil, R. W., & Kupiec‐Weglinski, J. W. (2008) · Molecular Medicine · doi:10.2119/2007-00134.vardanian · Cited by 159

Report of the first international liver transplantation society expert panel consensus conference on renal insufficiency in liver transplantation

Charlton, M., Wall, W. J., OJO, A. O., Ginès, P., Textor, S. C., Shihab, F. S., Marotta, P., Cantarovich, M., Eason, J. D., Wiesner, R. H., et al. (2009) · Liver Transplantation · doi:10.1002/lt.21877 · Cited by 159

SNO-hemoglobin is not essential for red blood cell–dependent hypoxic vasodilation

Isbell, T. S., Sun, C.-W., Wu, L.-C., Teng, X., Vitturi, D. A., Branch, B. G., Kevil, C. G., Peng, N., Wyss, J. M., Ambalavanan, N., et al. (2008) · Nature Medicine · doi:10.1038/nm1771 · Cited by 157

NO generation from inorganic nitrate and nitrite: Role in physiology, nutrition and therapeutics

Lundberg, J. O., & Weitzberg, E. (2009) · Archives of Pharmacal Research · doi:10.1007/s12272-009-1803-z · Cited by 153

Nitrate-Nitrite-Nitric Oxide Pathway: Implications for Anesthesiology and Intensive Care

Weitzberg, E., Hezel, M., Lundberg, J. O., & Warner, D. S. (2010) · Anesthesiology · doi:10.1097/aln.0b013e3181fcf3cc · Cited by 145

Hepatic ischemia-reperfusion injury in liver transplant setting: mechanisms and protective strategies

Rampes, S., & Ma, D. (2019) · Journal of Biomedical Research · doi:10.7555/jbr.32.20180087 · Cited by 148

Protective effect of platinum nano-antioxidant and nitric oxide against hepatic ischemia-reperfusion injury

Mu, J., Li, C., Shi, Y., Liu, G., Zou, J., Zhang, D., Jiang, C., Wang, X., He, L., Huang, P., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-29772-w · Cited by 145

Gaseotransmitters: New Frontiers for Translational Science

Szabó, C. (2010) · Science Translational Medicine · doi:10.1126/scitranslmed.3000721 · Cited by 139

Impact of hypoxic hepatitis on mortality in the intensive care unit

Fuhrmann, V., Kneidinger, N., Herkner, H., Heinz, G., Nikfardjam, M., Bojic, A., Schellongowski, P., Angermayr, B., Schöniger–Hekele, M., Madl, C., et al. (2011) · Intensive Care Medicine · doi:10.1007/s00134-011-2248-7 · Cited by 137

Primary graft dysfunction after liver transplantation

Chen, X.-B., & Xu, M. (2014) · Hepatobiliary & pancreatic diseases international · doi:10.1016/s1499-3872(14)60023-0 · Cited by 135

Preconditioning, organ preservation, and postconditioning to prevent ischemia-reperfusion injury to the liver

de Rougemont, O., Lehmann, K., & Clavien, P. (2009) · Liver Transplantation · doi:10.1002/lt.21876 · Cited by 134

Cross-talk Between Nitrate-Nitrite-NO and NO Synthase Pathways in Control of Vascular NO Homeostasis

Carlström, M., Liu, M., Yang, T., Zollbrecht, C., Huang, L., Peleli, M., Borniquel, S., Kishikawa, H., Hezel, M., Persson, A. E. G., et al. (2015) · Antioxidants & Redox Signaling · doi:10.1089/ars.2013.5481 · Cited by 130

Therapeutic Antioxidant Medical Gas

Nakao, A., Sugimoto, R., Billiar, T. R., & McCurry, K. R. (2009) · Journal of Clinical Biochemistry and Nutrition · doi:10.3164/jcbn.08-193r · Cited by 123

Mitochondrial Dysfunction and Autophagy in Hepatic Ischemia/Reperfusion Injury

Go, K. L., Lee, S., Zendejas, I. R., Behrns, K. E., & Js, K. (2015) · BioMed Research International · doi:10.1155/2015/183469 · Cited by 124

Hypoxic hepatitis – epidemiology, pathophysiology and clinical management

Fuhrmann, V., Jäger, B., Зубкова, А. О., & Drolz, A. (2010) · Wiener klinische Wochenschrift · doi:10.1007/s00508-010-1357-6 · Cited by 124

What is critical for liver surgery and partial liver transplantation

Clavien, P., Oberkofler, C. E., Raptis, D. A., Lehmann, K., Rickenbacher, A., & El‐Badry, A. M. (2010) · Hepatology · doi:10.1002/hep.23713 · Cited by 121

Inorganic nitrite therapy: historical perspective and future directions

Kevil, C. G., Kolluru, G. K., Pattillo, C. B., & Giordano, T. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.04.042 · Cited by 113

The use of high‐dose melatonin in liver resection is safe: first clinical experience

Nickkholgh, A., Schneider, H., Sobirey, M., Venetz, W. P., Hinz, U., Pelzl, L. H., Gotthardt, D. N., Čekauskas, A., Manikas, M., Mikalauskas, S., et al. (2011) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2011.00854.x · Cited by 110

Inhaled Nitric Oxide Improves Outcomes After Successful Cardiopulmonary Resuscitation in Mice

Minamishima, S., Kida, K., Tokuda, K., Wang, H., Sips, P. Y., Kosugi, S., Mandeville, J. B., Buys, E. S., Brouckaert, P., Liu, P. K., et al. (2011) · Circulation · doi:10.1161/circulationaha.111.025395 · Cited by 105

Brief Periods of Nitric Oxide Inhalation Protect against Myocardial Ischemia–Reperfusion Injury

Nagasaka, Y., Fernandez, B. O., Garcia-Saura, M. F., Petersen, B., Ichinose, F., Bloch, K. D., Feelisch, M., & Zapol, W. M. (2008) · Anesthesiology · doi:10.1097/aln.0b013e318186316e · Cited by 101

Ischemic postconditioning attenuates liver warm ischemia-reperfusion injury through Akt-eNOS-NO-HIF pathway

Guo, J., Yang, T., Sun, X. G., Zhou, N. Y., Li, F. S., Long, D., Lin, T., Li, P. Y., & Feng, L. (2011) · Journal of Biomedical Science · doi:10.1186/1423-0127-18-79 · Cited by 95

The nitric oxide pathway – evidence and mechanisms for protection against liver ischaemia reperfusion injury

Abu‐Amara, M., Yang, S. Y., Seifalian, A. M., Davidson, B. R., & Fuller, B. J. (2012) · Liver International · doi:10.1111/j.1478-3231.2012.02755.x · Cited by 91

Mitochondria as metabolizers and targets of nitrite

Shiva, S. (2010) · Nitric Oxide · doi:10.1016/j.niox.2009.09.002 · Cited by 87

Regulation of mitochondrial function and energetics by reactive nitrogen oxides

Larsen, F. J., Schiffer, T. A., Weitzberg, E., & Lundberg, J. O. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2012.08.580 · Cited by 87

Nitric Oxide and Redox Regulation in the Liver: Part II. Redox Biology in Pathologic Hepatocytes and Implications for Intervention

Diesen, D. L., & Kuo, P. C. (2009) · Journal of Surgical Research · doi:10.1016/j.jss.2009.10.006 · Cited by 85

Regulation of mitochondrial oxidative phosphorylation through tight control of cytochrome c oxidase in health and disease – Implications for ischemia/reperfusion injury, inflammatory diseases, diabetes, and cancer

Pham, L., Arroum, T., Wan, J., Pavelich, L., Bell, J., Morse, P. T., Lee, I., Grossman, L. I., Sanderson, T. H., Malek, M. H., et al. (2024) · Redox Biology · doi:10.1016/j.redox.2024.103426 · Cited by 92

Biological modulation of liver ischemia–reperfusion injury

de Rougemont, O., Dutkowski, P., & Clavien, P. (2010) · Current Opinion in Organ Transplantation · doi:10.1097/mot.0b013e3283373ced · Cited by 80

Nitrite and Nitrite Reductases: From Molecular Mechanisms to Significance in Human Health and Disease

Castiglione, N., Rinaldo, S., Giardina, G., Stelitano, V., & Cutruzzolà, F. (2012) · Antioxidants and Redox Signaling · doi:10.1089/ars.2011.4196 · Cited by 81

Role of nitric oxide in hepatic ischemia-reperfusion injury

Siriussawakul, A. (2010) · World Journal of Gastroenterology · doi:10.3748/wjg.v16.i48.6079 · Cited by 77

Working with nitric oxide and hydrogen sulfide in biological systems

Yuan, S. S., Patel, R. P., & Kevil, C. G. (2014) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00327.2014 · Cited by 74

Clinical translation of nitrite therapy for cardiovascular diseases

Calvert, J. W., & Lefer, D. J. (2010) · Nitric Oxide · doi:10.1016/j.niox.2009.11.001 · Cited by 72

rPSGL-Ig for Improvement of Early Liver Allograft Function: A Double-Blind, Placebo-Controlled, Single-Center Phase II Study†

Busuttil, R. W., Lipshutz, G. S., Kupiec‐Weglinski, J. W., Ponthieux, S., Gjertson, D. W., Cheadle, C., Watkins, T., Ehrlich, E., Katz, E., Squiers, E. C., et al. (2011) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2011.03441.x · Cited by 72

Nitrate/Nitrite as Critical Mediators to Limit Oxidative Injury and Inflammation

Waltz, P., Escobar, D., Botero, A. M., & Zuckerbraun, B. S. (2015) · Antioxidants & Redox Signaling · doi:10.1089/ars.2015.6256 · Cited by 70

Activation of Parenchymal CD47 Promotes Renal Ischemia-Reperfusion Injury

Rogers, N. M., Thomson, A. W., & Isenberg, J. S. (2012) · Journal of the American Society of Nephrology · doi:10.1681/asn.2012020137 · Cited by 70

Erythrocyte storage increases rates of NO and nitrite scavenging: implications for transfusion-related toxicity

Stapley, R. D., Owusu, B. Y., Brandon, A. P., Cusick, M. V., Rodriguez, C. A., Marques, M. B., Kerby, J. D., Barnum, S. R., Weinberg, J. A., Lancaster, J. R., et al. (2012) · Biochemical Journal · doi:10.1042/bj20120675 · Cited by 68

Convergence of biological nitration and nitrosation via symmetrical nitrous anhydride

Vitturi, D. A., Minarrieta, L., Salvatore, S. R., Postlethwait, E. M., Fazzari, M., Ferrer-Sueta, G., Lancaster, J. R., Freeman, B. A., & Schopfer, F. J. (2015) · Nature Chemical Biology · doi:10.1038/nchembio.1814 · Cited by 65

Regulation of nitrite transport in red blood cells by hemoglobin oxygen fractional saturation

Vitturi, D. A., Teng, X., Toledo, J. C., Matalon, S., Lancaster, J. R., & Patel, R. P. (2009) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01303.2008 · Cited by 62

Nitrite in organ protection

Rassaf, T., Ferdinandy, P., & Schulz, R. (2014) · British Journal of Pharmacology · doi:10.1111/bph.12291 · Cited by 62

Randomized Controlled Trial of Inhaled Nitric Oxide for the Treatment of Microcirculatory Dysfunction in Patients With Sepsis*

Trzeciak, S., Glaspey, L. J., Dellinger, R. P., Durflinger, P., Anderson, K., Dezfulian, C., Roberts, B. W., Chansky, M. E., Parrillo, J. E., & Hollenberg, S. M. (2014) · Critical Care Medicine · doi:10.1097/ccm.0000000000000549 · Cited by 62

Biological modulation of renal ischemia–reperfusion injury

Snoeijs, M. G., van Heurn, E. L. W., & Buurman, W. A. (2010) · Current Opinion in Organ Transplantation · doi:10.1097/mot.0b013e32833593eb · Cited by 59

Inhaled nitric oxide: Current clinical concepts

Bhatraju, P. K., Crawford, J. H., Hall, M. K., & Lang, J. D. (2015) · Nitric Oxide · doi:10.1016/j.niox.2015.08.007 · Cited by 58

Resveratrol and exercise combined to treat functional limitations in late life: A pilot randomized controlled trial

Harper, S. A., Bassler, J. R., Peramsetty, S., Yang, Y., Roberts, L. M., Drummer, D. J., Mankowski, R. T., Leeuwenburgh, C., Ricart, K. C., Patel, R. P., et al. (2020) · Experimental Gerontology · doi:10.1016/j.exger.2020.111111 · Cited by 56

Review of Inhaled Nitric Oxide in the Pediatric Cardiac Surgery Setting

Checchia, P. A., Bronicki, R. A., & Goldstein, B. (2012) · Pediatric Cardiology · doi:10.1007/s00246-012-0172-4 · Cited by 55

Molecular mechanisms of liver preconditioning

Alchera, E. (2010) · World Journal of Gastroenterology · doi:10.3748/wjg.v16.i48.6058 · Cited by 54

Beneficial Effects of Nitric Oxide on Outcomes after Cardiac Arrest and Cardiopulmonary Resuscitation in Hypothermia-treated Mice

Kida, K., Shirozu, K., Yu, B., Mandeville, J. B., Bloch, K. D., & Ichinose, F. (2014) · Anesthesiology · doi:10.1097/aln.0000000000000149 · Cited by 52

Inhaled Nitric Oxide Therapy Increases Blood Nitrite, Nitrate, and S-Nitrosohemoglobin Concentrations in Infants with Pulmonary Hypertension

Ibrahim, Y., Ninnis, J. R., Hopper, A. O., Deming, D. D., Zhang, A. X., Herring, J. L., Sowers, L. C., McMahon, T., Power, G. G., & Blood, A. B. (2011) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2011.07.040 · Cited by 52

Inhaled nitric oxide: role in the pathophysiology of cardio-cerebrovascular and respiratory diseases

Signori, D., Magliocca, A., Hayashida, K., Graw, J. A., Malhotra, R. K., Bellani, G., Berra, L. M., & Rezoagli, E. (2022) · Intensive Care Medicine Experimental · doi:10.1186/s40635-022-00455-6 · Cited by 54

The Influence of Pharmacological Preconditioning with Sevoflurane on Incidence of Early Allograft Dysfunction in Liver Transplant Recipients

Minou, A. F., Михайлович, Д. А., Shcherba, A. E., & Руммо, О. О. (2012) · Anesthesiology Research and Practice · doi:10.1155/2012/930487 · Cited by 50

Mitigation of chlorine gas lung injury in rats by postexposure administration of sodium nitrite

Yadav, A. K., Doran, S. F., Samal, A. A., Sharma, R., Vedagiri, K., Postlethwait, E. M., Squadrito, G. L., Fanucchi, M. V., Roberts, L. J., Patel, R. P., et al. (2010) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00278.2010 · Cited by 50

Innate and adaptive immune responses subsequent to ischemia-reperfusion injury in the kidney

Denecke, C., & Tullius, S. G. (2014) · The French Journal of Urology · doi:10.1016/s1166-7087(14)70058-2 · Cited by 48

Dietary intake and bio-activation of nitrite and nitrate in newborn infants

Jones, J. A., Hopper, A. O., Power, G. G., & Blood, A. B. (2014) · Pediatric Research · doi:10.1038/pr.2014.168 · Cited by 50

Impact of brain death on ischemia/reperfusion injury in liver transplantation

Dziodzio, T., Biebl, M., & Pratschke, J. (2014) · Current Opinion in Organ Transplantation · doi:10.1097/mot.0000000000000061 · Cited by 47

Nitric Oxide Donor Agents for the Treatment of Ischemia/Reperfusion Injury in Human Subjects

Roberts, B. W., Mitchell, J., Kilgannon, J. H., Chansky, M. E., & Trzeciak, S. (2013) · Shock · doi:10.1097/shk.0b013e31827f565b · Cited by 47

Erythrocyte-dependent regulation of human skeletal muscle blood flow: role of varied oxyhemoglobin and exercise on nitrite, S-nitrosohemoglobin, and ATP

Dufour, S. P., Patel, R. P., Brandon, A., Teng, X., Pearson, J., Barker, H., Ali, L., Yuen, A. H. Y., Smolenski, R. T., & González-Alonso, J. (2010) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00389.2010 · Cited by 45

Current protective strategies in liver surgery

Gurusamy, K. S. (2010) · World Journal of Gastroenterology · doi:10.3748/wjg.v16.i48.6098 · Cited by 44

Remote Ischemic Conditioning Prevents Lung and Liver Injury After Hemorrhagic Shock/Resuscitation

Leung, C. H., Caldarone, C. A., Wang, F., Venkateswaran, S., Ailenberg, M., Vadasz, B., Wen, X., & Rotstein, O. D. (2014) · Annals of Surgery · doi:10.1097/sla.0000000000000877 · Cited by 44

Inhaled nitric oxide improves transpulmonary blood flow and clinical outcomes after prolonged cardiac arrest: a large animal study

Derwall, M., Ebeling, A., Nolte, K. W., Weis, J., Rossaint, R., Ichinose, F., Nix, C., Fries, M., & Brücken, A. (2015) · Critical Care · doi:10.1186/s13054-015-1050-2 · Cited by 43

Inorganic nitrite and chronic tissue ischaemia: a novel therapeutic modality for peripheral vascular diseases

Pattillo, C. B., Bir, S. C., Rajaram, V., & Kevil, C. G. (2010) · Cardiovascular Research · doi:10.1093/cvr/cvq297 · Cited by 44

H2S Regulation of Nitric Oxide Metabolism

Kolluru, G. K., Yuan, S. S., Shen, X., & Kevil, C. G. (2015) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/bs.mie.2014.11.040 · Cited by 43

Ischemic preconditioning of the liver: A few perspectives from the bench to bedside translation

Desai, K. K., Dikdan, G. S., Shareef, A., & Koneru, B. (2008) · Liver Transplantation · doi:10.1002/lt.21630 · Cited by 43

Nitric oxide signalling and neuronal nitric oxide synthase in the heart under stress

Zhang, Y. H. (2017) · F1000Research · doi:10.12688/f1000research.10128.1 · Cited by 42

Dexmedetomidine exerts a protective effect on ischemia-reperfusion injury after hepatectomy: A prospective, randomized, controlled study

Zhang, Y., Liu, M., Yu, Y., Cao, J., & Mi, W. (2019) · Journal of Clinical Anesthesia · doi:10.1016/j.jclinane.2019.109631 · Cited by 42

Clamping techniques and protecting strategies in liver surgery

Lesurtel, M., Lehmann, K., de Rougemont, O., & Clavien, P. (2009) · HPB · doi:10.1111/j.1477-2574.2009.00066.x · Cited by 42

Ischemic Postconditioning of the Liver Graft in Adult Liver Transplantation

Ricca, L., Lemoine, A., Cauchy, F., Hamelin, J., Sebagh, M., Esposti, D. D., Salloum, C., Vibert, É., Balducci, G., & Azoulay, D. (2015) · Transplantation · doi:10.1097/tp.0000000000000685 · Cited by 42

Graft Dysfunction and Management in Liver Transplantation

Kok, B., Dong, V. M., & Karvellas, C. J. (2018) · Critical Care Clinics · doi:10.1016/j.ccc.2018.08.002 · Cited by 41

A Randomized Clinical Trial Testing the Anti-Inflammatory Effects of Preemptive Inhaled Nitric Oxide in Human Liver Transplantation

Lang, J. D., Smith, A. B., Brandon, A. P., Bradley, K. M., Liu, Y., Li, W., Crowe, D. R., Jhala, N. C., Cross, R. C., Frenette, L., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0086053 · Cited by 40

Intravenous Infusion of Dexmedetomidine Combined Isoflurane Inhalation Reduces Oxidative Stress and Potentiates Hypoxia Pulmonary Vasoconstriction during One‐Lung Ventilation in Patients

Xia, R., Xu, J., Yin, H. X., Wu, H., Xia, Z., Zhou, D., Xia, Z.-Y., Zhang, L., Li, H., & Xiao, X. (2015) · Mediators of Inflammation · doi:10.1155/2015/238041 · Cited by 39

Potential biomarkers of tissue hypoxia during acute hemodilutional anemia in cardiac surgery: A prospective study to assess tissue hypoxia as a mechanism of organ injury

Hare, G. M. T., Han, K., Leshchyshyn, Y., Mistry, N., Kei, T., Dai, S. Y., Tsui, A. K. Y., Pirani, R. A., Honavar, J., Patel, R. P., et al. (2018) · Canadian Journal of Anesthesia/Journal canadien d anesthésie · doi:10.1007/s12630-018-1140-0 · Cited by 39

Myocardial Protection by Nitrite: Evidence That This Reperfusion Therapeutic Will Not Be Lost in Translation

Sinha, S. S., Shiva, S., & Gladwin, M. T. (2008) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2008.05.001 · Cited by 37

Evidence Mounts That Nitrite Contributes to Hypoxic Vasodilation in the Human Circulation

Gladwin, M. T. (2008) · Circulation · doi:10.1161/circulationaha.107.753897 · Cited by 36

Skeletal Muscle Nitrate as a Regulator of Systemic Nitric Oxide Homeostasis

Piknova, B., Schechter, A. N., Park, J. W., Vanhatalo, A., & Jones, A. M. (2021) · Exercise and Sport Sciences Reviews · doi:10.1249/jes.0000000000000272 · Cited by 38

Rb1 postconditioning attenuates liver warm ischemia–reperfusion injury through ROS-NO-HIF pathway

Guo, Y., Yang, T., Lu, J. L., Li, S., Wan, L., Long, D., Li, Q., Li, F., & Li, Y. (2011) · Life Sciences · doi:10.1016/j.lfs.2011.01.022 · Cited by 35

The Reperfusion Syndrome: Have We Made Any Progress?

Ramsay, M. A. E. (2008) · Liver Transplantation · doi:10.1002/lt.21418 · Cited by 35

How to protect liver graft with nitric oxide

Abdennebi, H. B. (2011) · World Journal of Gastroenterology · doi:10.3748/wjg.v17.i24.2879 · Cited by 39

Gaseous Signaling Molecules in Cardiovascular Function: From Mechanisms to Clinical Translation

Lee, S. R., Nilius, B., & Han, J. (2018) · Reviews of physiology, biochemistry and pharmacology · doi:10.1007/112_2017_7 · Cited by 35

Pharmacological preconditioning with inhaled nitric oxide (NO): Organ-specific differences in the lifetime of blood and tissue NO metabolites

Nagasaka, Y., Fernandez, B. O., Steinbicker, A. U., Spagnolli, E., Malhotra, R. K., Bloch, D. B., Bloch, K. D., Zapol, W. M., & Feelisch, M. (2018) · Nitric Oxide · doi:10.1016/j.niox.2018.08.006 · Cited by 35

DETANO and Nitrated Lipids Increase Chloride Secretion across Lung Airway Cells

Chen, L., Bosworth, C. A., Pico, T., Collawn, J. F., Varga, K., Gao, Z., Clancy, J. P., Fortenberry, J. A., Lancaster, J. R., & Matalon, S. (2008) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2008-0005oc · Cited by 35

The Hepatoprotective Effect of Sodium Nitrite on Cold Ischemia-Reperfusion Injury

Li, W., Meng, Z., Liu, Y., Patel, R. P., & Lang, J. D. (2012) · Journal of Transplantation · doi:10.1155/2012/635179 · Cited by 34

Mechanisms of liver involvement in systemic disease

Edwards, L., & Wanless, I. R. (2013) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/j.bpg.2013.08.002 · Cited by 34

Minimizing Ischemia Reperfusion Injury in Xenotransplantation

Patel, P. M., Connolly, M. R., Coe, T. M., Calhoun, A., Pollok, F., Markmann, J. F., Burdorf, L., Azimzadeh, A. M., Madsen, J. C., & Pierson, R. N. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.681504 · Cited by 33

Changing Perspectives from Oxidative Stress to Redox Signaling—Extracellular Redox Control in Translational Medicine

Palacio, P. L., Godoy, J. R., Aktaş, O., & Hanschmann, E.-M. (2022) · Antioxidants · doi:10.3390/antiox11061181 · Cited by 32

The inhaled route to improved liver function

Sharland, A. F., Kowdley, K. V., McCaughan, G. W., & Trautwein, C. (2008) · Hepatology · doi:10.1002/hep.22190

Inhaled nitrogen oxide prevents inflammatory liver damage after transplantation

(2007) · Nature Clinical Practice Gastroenterology & Hepatology · doi:10.1038/ncpgasthep0968

A Randomized Clinical Trial Testing the Anti-Inflammatory Effects of Preemptive Inhaled Nitric Oxide in Human Liver Transplantation

Lang, J. D., Smith, A. B., Brandon, A. P., Bradley, K. M., Liu, Y., Li, W., Crowe, D. R., Jhala, N. C., Cross, R. C., Frenette, L., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0086053 · Cited by 40

A Randomized Trial of Inhaled Nitric Oxide to Prevent Ischemia–Reperfusion Injury after Lung Transplantation

Meade, M. O., Granton, J. T., Matte-Martyn, A., McRae, K. M., Weaver, B., Cripps, P., & Keshavjee, S. H. (2003) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.2203034 · Cited by 186

Nitric oxide and hepatic ischemic injury in human orthotopic liver transplantation.

Esteban, F., Gomez-Jimenez, J., Mc, M., Ruíz, J. C., Nuvials, X., Garcia-Allut, J. L., Saurí, R., Murio, J. E., Mourelle, M., & Segura, R. (1995) · PubMed · Cited by 11