The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Nociceptors: the sensors of the pain pathway
Open accessAbstract
Specialized peripheral sensory neurons known as nociceptors alert us to potentially damaging stimuli at the skin by detecting extremes in temperature and pressure and injury-related chemicals, and transducing these stimuli into long-ranging electrical signals that are relayed to higher brain centers. The activation of functionally distinct cutaneous nociceptor populations and the processing of information they convey provide a rich diversity of pain qualities. Current work in this field is providing researchers with a more thorough understanding of nociceptor cell biology at molecular and systems levels and insight that will allow the targeted design of novel pain therapeutics.
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Citations
Cites
Cellular and Molecular Mechanisms of Pain
Basbaum, A. I., Bautista, D. M., Scherrer, G., & Julius, D. (2009) · Cell · doi:10.1016/j.cell.2009.09.028 · Cited by 4,344
Central sensitization: a generator of pain hypersensitivity by central neural plasticity
Latremoliere, A., & Woolf, C. J. (2009) · The Journal of Pain · doi:10.1016/j.jpain.2009.06.012 · Cited by 3,913
Le Bars, D., Gozariu, M., & Cadden, S. W. (2001) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01514-x · Cited by 1,459 · cited 4×
“Advances are hampered by the difficulties inherent in studying neuronal processes in humans, cellular changes in nociceptors induced by invasive methods, the inability to record directly from the tiny structures where transduction of noxious stimuli occurs, and the uncertainty in model systems that an animal’s behavio…”
BackgroundInfluentialNociceptors: a phylogenetic view
Smith, E. S. J., & Lewin, G. R. (2009) · Journal of Comparative Physiology A · doi:10.1007/s00359-009-0482-z · Cited by 271
Intracellular Signaling in Primary Sensory Neurons and Persistent Pain
Cheng, J.-K., & Ji, R.-R. (2008) · Neurochemical Research · doi:10.1007/s11064-008-9711-z · Cited by 266
Role of psychology in pain management
Eccleston, C. (2001) · British Journal of Anaesthesia · doi:10.1093/bja/87.1.144 · Cited by 235
Cited by
Feldman, E. L., Callaghan, B. C., Pop-Busui, R., Zochodne, D. W., Wright, D. E., Bennett, D. L., Bril, V., Russell, J. W., & Viswanathan, V. (2019) · Nature Reviews Disease Primers · doi:10.1038/s41572-019-0092-1 · Cited by 1,697
The Role of Voltage-Gated Sodium Channels in Pain Signaling
Bennett, D. L., Clark, A. J., Huang, J., Waxman, S. G., & Dib-Hajj, S. D. (2019) · Physiological Reviews · doi:10.1152/physrev.00052.2017 · Cited by 730
What is this thing called pain?
Woolf, C. J. (2010) · Journal of Clinical Investigation · doi:10.1172/jci45178 · Cited by 593
Molecular and functional neuroscience in immunity
Pavlov, V. A., Chavan, S. S., & Tracey, K. J. (2018) · Annual Review of Immunology · doi:10.1146/annurev-immunol-042617-053158 · Cited by 444
He, L., He, T., Xing, J., Zhou, Q., Fan, L., Liu, C., Chen, Y., Wu, D., Tian, Z., Liu, B., et al. (2020) · Stem Cell Research & Therapy · doi:10.1186/s13287-020-01781-w · Cited by 435
Metadata
- Authors
- Dubin, A. E., & Patapoutian, A.
- Venue
- Journal of Clinical Investigation
- Published
- 2010-11-01
- Volume
- 120
- Issue
- 11
- Pages
- 3760-3772
- ISSN
- 0021-9738 (ISSN-L)
- OpenAlex
- W2140115878
- Cited by
- 1,409
- References
- 6
- FWCI
- 9.51
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
