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Cited by 395

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice

Raabe, Martin, Véniant, Murielle M., Sullivan, Meghan A., Zlot, Constance H., Björkegren, Johan, Nielsen, Lars Bo, Wong, Jinny S., Hamilton, Robert L., Young, Stephen G.·1999·Journal of Clinical Investigation
DOI 10.1172/jci6576
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Crossref · 10.1172/jci6576

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  • MTTP is transcriptionally regulated by SREBPs, and lack of MTTP results in APOB cotranslational degradation.

    “MTTP is transcriptionally regulated by SREBPs, and the lack of MTTP results in APOB cotranslational degradation (29–31).”

    From Hypomorphic ASGR1 modulates lipid homeostasis via INSIG1-mediated SREBP signaling suppression (2021) · cites this paper as [29]

    The Introduction says that adding lipids to apo B as it is translated is thought to help it avoid degradation, and the results section reports substantially reduced apo B-100 secretion from Mttp-deficient hepatocytes. Neither passage establishes that the loss causes cotranslational degradation; the paper also reports little change in apo B-48 secretion. The passages do not support the claim that SREBPs transcriptionally regulate MTTP (section labels available; page numbers not provided). (LLM, conf=0.84)

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Metadata

Authors
Raabe, M., Véniant, M. M., Sullivan, M. A., Zlot, C. H., Björkegren, J., Nielsen, L. B., Wong, J. S., Hamilton, R. L., & Young, S. G.
Venue
Journal of Clinical Investigation
Publisher
American Society for Clinical Investigation
Published
1999-05-01
Volume
103
Issue
9
Pages
1287-1298
ISSN
0021-9738
DOI
10.1172/jci6576
Cited by
395
References
1
Language
en

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