The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
ER phospholipid composition modulates lipogenesis during feeding and in obesity
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Loss of hepatic LPCAT3 reduces ER membrane desaturation and has the opposite outcome on SREBP1c signaling.
“Reciprocally, loss of hepatic LPCAT3, which reduces ER membrane desaturation, has the opposite outcome on SREBP1c signaling.”
From Loss of the E3 ubiquitin ligase MARCHF6 alters hepatic lipid metabolism and drives spontaneous hepatosteatosis (2026) · cites this paper as [57]
Specific lipid species in the ER membrane or the degree of ER membrane desaturation are strong determinants of hepatic SREBP1c activation.
“Alternatively, specific lipid species in the ER membrane or the degree of ER membrane desaturation are strong determinants of hepatic SREBP1c activation.”
From Loss of the E3 ubiquitin ligase MARCHF6 alters hepatic lipid metabolism and drives spontaneous hepatosteatosis (2026) · cites this paper as [57]
Hepatic LPCAT3-mediated incorporation of polyunsaturated FA into phospholipids increases ER membrane desaturation and promotes SREBP1c activation.
“Additionally, studies have demonstrated that hepatic LPCAT3-mediated incorporation of polyunsaturated FA into phospholipids increases the ER membrane desaturation and concomitantly promotes SREBP1c activation [57].”
From Loss of the E3 ubiquitin ligase MARCHF6 alters hepatic lipid metabolism and drives spontaneous hepatosteatosis (2026) · cites this paper as [57]
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A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION
Bligh, E. G., & Dyer, W. J. (1959) · Canadian Journal of Biochemistry and Physiology · doi:10.1139/o59-099 · Cited by 54,751
Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy
Shimomura, I., Hammer, R. E., Ikemoto, S., Brown, M. S., & Goldstein, J. L. (1999) · Nature · doi:10.1038/43448 · Cited by 1,038
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Cited by
Sorted by citations
Liver X receptors in lipid signalling and membrane homeostasis
Wang, B., & Tontonoz, P. (2018) · Nature Reviews Endocrinology · doi:10.1038/s41574-018-0037-x · Cited by 722
Self-citationInhibition of cholesterol biosynthesis through RNF145-dependent ubiquitination of SCAP
Zhang, L., Rajbhandari, P., Priest, C., Sandhu, J., Wu, X., Temel, R., Castrillo, A., de Aguiar Vallim, T. Q., Sallam, T., & Tontonoz, P. (2017) · eLife · doi:10.7554/elife.28766 · Cited by 69
Self-citationHepatic deletion of Mboat7 (LPIAT1) causes activation of SREBP-1c and fatty liver
Xia, M., Chandrasekaran, P., Rong, S., Fu, X., & Mitsche, M. A. (2021) · Journal of Lipid Research · doi:10.1194/jlr.ra120000856 · Cited by 60
Nuclear receptors and liver disease: summary of the 2017 basic research symposium
Tran, M., Liu, Y., Huang, W., & Wang, L. (2018) · Hepatology Communications · doi:10.1002/hep4.1203 · Cited by 20
Sachdev, V., van Loon, N. M., Kingma, J., Ottenhoff, R., Tan, J. M. E., van den Berg, M., Duijst, S., Jongejan, A., Levels, J. H. M., Rensen, P. C. N., et al. (2026) · Molecular Metabolism · doi:10.1016/j.molmet.2026.102379 · Cited by 1
Metadata
- Authors
- Rong, X., Wang, B., Palladino, E. N. D., de Aguiar Vallim, T. Q., Ford, D. A., & Tontonoz, P.
- ORCID
- Tontonoz, Peter
- Venue
- Journal of Clinical Investigation
- Published
- 2017-08-28
- Volume
- 127
- Issue
- 10
- Pages
- 3640-3651
- ISSN
- 0021-9738
- 1558-8238
- Cited by
- 90
- References
- 2
- Language
- en
- Funders
- NHLBI (HL030568)
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