A role for NF-κB–dependent gene transactivation in sunburn

Nuclear Factor-κB — A Pivotal Transcription Factor in Chronic Inflammatory Diseases

Barnes, P. J., & Karin, M. (1997) · New England Journal of Medicine · doi:10.1056/nejm199704103361506 · Cited by 4,622 · see citing works

CpG motifs in bacterial DNA trigger direct B-cell activation

Krieg, A. M., Yi, A.-K., Matson, S., Waldschmidt, T. J., Bishop, G. A., Teasdale, R., Koretzky, G. A., & Klinman, D. M. (1995) · Nature · doi:10.1038/374546a0 · Cited by 3,508 · see citing works

JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

Dérijard, B., Hibi, M., Wu, I.-H., Barrett, T., Su, B., Deng, T., Karin, M., & Davis, R. J. (1994) · Cell · doi:10.1016/0092-8674(94)90380-8 · Cited by 3,188 · see citing works

NF-κB: Ten Years After

Baeuerle, P. A., & Baltimore, D. (1996) · Cell · doi:10.1016/s0092-8674(00)81318-5 · Cited by 3,002 · see citing works

The anti-inflammatory agents aspirin and salicylate inhibit the activity of IκB kinase-β

Yin, M.-J., Yamamoto, Y., & Gaynor, R. B. (1998) · Nature · doi:10.1038/23948 · Cited by 1,596 · see citing works

Ultraviolet Light and Osmotic Stress: Activation of the JNK Cascade Through Multiple Growth Factor and Cytokine Receptors

Rosette, C., & Karin, M. (1996) · Science · doi:10.1126/science.274.5290.1194 · Cited by 1,034 · see citing works

DNA Damaging Agents Induce Expression of Fas Ligand and Subsequent Apoptosis in T Lymphocytes via the Activation of NF-κB and AP-1

Kasibhatla, S., Brunner, T., Genestier, L., Echeverri, F., Mahboubi, A., & Green, D. R. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80054-4 · Cited by 721 · see citing works

Human keratinocytes are a source for tumor necrosis factor alpha: evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light.

Köck, A., Schwarz, T., Kirnbauer, R., Urbanski, A., Perry, P., Ansel, J. C., & Luger, T. A. (1990) · The Journal of Experimental Medicine · doi:10.1084/jem.172.6.1609 · Cited by 712 · see citing works

Activation of the IκBα Kinase Complex by MEKK1, a Kinase of the JNK Pathway

Lee, F. S., Hagler, J., Chen, Z. J., & Maniatis, T. (1997) · Cell · doi:10.1016/s0092-8674(00)81842-5 · Cited by 710 · see citing works

CpG DNA: A potent signal for growth, activation, and maturation of human dendritic cells

Hartmann, G., Weiner, G. J., & KRIEG, A. M. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.16.9305 · Cited by 617 · see citing works

ATF‐2 is preferentially activated by stress‐activated protein kinases to mediate c‐jun induction in response to genotoxic agents.

van Dam, H., Wilhelm, D., Herr, I., Steffen, A., Herrlich, P. A., & Angel, P. E. (1995) · The EMBO Journal · doi:10.1002/j.1460-2075.1995.tb07168.x · Cited by 598 · see citing works

In vivo transfection of cis element “decoy” against nuclear factor- κB binding site prevents myocardial infarction

Morishita, R., Sugimoto, T., Aoki, M., Kida, I., Tomita, N., Moriguchi, A., Maeda, K., Sawa, Y., Kaneda, Y., Higaki, J., et al. (1997) · Nature Medicine · doi:10.1038/nm0897-894 · Cited by 584 · see citing works

Increased Microvascular Density and Enhanced Leukocyte Rolling and Adhesion in the Skin of VEGF Transgenic Mice

Detmar, M. J., Brown, L. F., Schön, M. P., Elicker, B. M., Velasco, P., Richard, L., Fukumura, D., Monsky, W. L., Claffey, K. P., & Jain, R. K. (1998) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.1998.00262.x · Cited by 550 · see citing works

Activation of Cutaneous Dendritic Cells by CpG-Containing Oligodeoxynucleotides: A Role for Dendritic Cells in the Augmentation of Th1 Responses by Immunostimulatory DNA

Jakob, T., Walker, P., Krieg, A. Μ., Udey, M. C., & Vogel, J. C. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.161.6.3042 · Cited by 535 · see citing works

Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents.

Knebel, A., Rahmsdorf, H. J., Ullrich, A., & Herrlich, P. A. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00916.x · Cited by 514 · see citing works

Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice.Preprint

Beg, A. A., Sha, W. C., Bronson, R. T., & Baltimore, D. (1995) · Genes & Development · doi:10.1101/gad.9.22.2736 · Cited by 473 · see citing works

Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L

Aragane, Y., Kulms, D., Metze, D., Wilkes, G., Pöppelmann, B., Luger, T. A., & Schwarz, T. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.140.1.171 · Cited by 463 · see citing works

The roles of hydrogen peroxide and superoxide as messengers in the activation of transcription factor NF-κB

Schmidt, K. N., Amstad, P., Cerutti, P., & Baeuerle, P. A. (1995) · Chemistry & Biology · doi:10.1016/1074-5521(95)90076-4 · Cited by 454 · see citing works

Overexpression of TAR sequences renders cells resistant to human immunodeficiency virus replication

Sullenger, B. A., Gallardo, H. F., Ungers, G. E., & Gilboa, E. (1990) · Cell · doi:10.1016/0092-8674(90)90455-n · Cited by 443 · see citing works

Uncoupling of Nonreceptor Tyrosine Kinases from PLC-γ1 in an SLP-76-Deficient T Cell

Yablonski, D., Kuhné, M. R., Kadlecek, T. A., & Weiss, A. (1998) · Science · doi:10.1126/science.281.5375.413 · Cited by 413 · see citing works

UV-induced reactive oxygen species in photocarcinogenesis and photoaging.

Scharffetter‐­Kochanek, K., Wlaschek, M., Brenneisen, P., Schauen, M., Blaudschun, R., & Wenk, J. (1997) · PubMed · Cited by 406 · see citing works

Analysis of the mechanism of unresponsiveness produced by haptens painted on skin exposed to low dose ultraviolet radiation

Elmets, C. A., Bergstresser, P. R., Tigelaar, R. E., Wood, P. J., & Streilein, J. W. (1983) · The Journal of experimental medicine · doi:10.1084/jem.158.3.781 · Cited by 392 · see citing works

Regulation of Gene Expression with Double-Stranded Phosphorothioate Oligonucleotides

Bielinska, A. U., Shivdasani, R. A., Zhang, L., & Nabel, G. J. (1990) · Science · doi:10.1126/science.2237444 · Cited by 372 · see citing works

Mechanisms of Ultraviolet Light‐Induced Pigmentation

Gilchrest, B. A., Park, H., Eller, M. S., & Yaar, M. (1996) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1996.tb02988.x · Cited by 364 · see citing works

IκBα Deficiency Results in a Sustained NF-κB Response and Severe Widespread Dermatitis in Mice

Klement, J. F., Rice, N. R., Car, B. D., Abbondanzo, S. J., Powers, G. D., Bhatt, H., Chen, C.-H., Rosen, C. A., & Stewart, C. L. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.5.2341 · Cited by 340 · see citing works

A survey of transformation markers in differentiating epidermal cell lines in culture.

Yuspa, S. H., Hawley‐Nelson, P., Koehler, B., & Stanley, J. R. (1980) · PubMed · Cited by 324 · see citing works

Activation of human B cells by phosphorothioate oligodeoxynucleotides.

Liang, H., Nishioka, Y., Reich, C. F., Pisetsky, D. S., & Lipsky, P. E. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118894 · Cited by 284 · see citing works

Evidence that Singlet Oxygen-induced Human T Helper Cell Apoptosis Is the Basic Mechanism of Ultraviolet-A Radiation Phototherapy

Morita, A., Werfel, T., Stege, H., Ahrens, C., Karmann, K., Grewe, M., Grether‐Beck, S., Ruzicka, T., Kapp, A., Klotz, L., et al. (1997) · The Journal of Experimental Medicine · doi:10.1084/jem.186.10.1763 · Cited by 280 · see citing works

DNA damage enhances melanogenesis.

Eller, M. S., Ostrom, K., & Gilchrest, B. A. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.3.1087 · Cited by 278 · see citing works

Coordinate Regulation of IκB Kinases by Mitogen-Activated Protein Kinase Kinase Kinase 1 and NF-κB-Inducing Kinase

Nemoto, S., DiDonato, J. A., & Lin, A. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.12.7336 · Cited by 224 · see citing works

Ultraviolet Light Induces Increased Circulating Interleukin-6 in Humans

Urbanski, A., Schwarz, T., Neuner, P., Krutmann, J., Kirnbauer, R., Luger, T. A., & Köck, A. (1990) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12874666 · Cited by 221 · see citing works

Activation of transcription factor AP-2 mediates UVA radiation- and singlet oxygen-induced expression of the human intercellular adhesion molecule 1 gene

Grether‐Beck, S., Olaizola‐Horn, S., Schmitt, H., Grewe, M., Jahnke, A., Johnson, J. P., Briviba, K., Sies, H., & Krutmann, J. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.25.14586 · Cited by 212 · see citing works

CREB is activated by UVC through a p38/HOG‐1‐dependent protein kinase

Iordanov, M. S., Bender, K., Ade, T., Schmid, W., Sachsenmaier, C., Engel, K., Gaestel, M., Rahmsdorf, H. J., & Herrlich, P. (1997) · The EMBO Journal · doi:10.1093/emboj/16.5.1009 · Cited by 210 · see citing works

Enhancement of DNA repair in human skin cells by thymidine dinucleotides: Evidence for a p53-mediated mammalian SOS response

Eller, M. S., Maeda, T., Magnoni, C., Atwal, D., & Gilchrest, B. A. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.23.12627 · Cited by 204 · see citing works

Genomic Organization of Human and Mouse Genes for Vascular Endothelial Growth Factor C

Chilov, D., Kukk, E., Taira, S., Jeltsch, M., Kaukonen, J., Palotie, A. V., Joukov, V., & Alitalo, K. K. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.40.25176 · Cited by 203 · see citing works

UVB Light Induces Nuclear Factor κB (NFκB) Activity Independently from Chromosomal DNA Damage in Cell-Free Cytosolic Extracts

Simon, M. M., Aragane, Y., Schwarz, A., Luger, T. A., & Schwarz, T. (1994) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12372194 · Cited by 167 · see citing works

The Effect of In Vitro and In Vivo UV Irradiation on the Production of ETAF Activity by Human and Murine Keratinocytes

Ansel, J. C., Luger, T. A., & Green, I. (1983) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12522862 · Cited by 164 · see citing works

Ultraviolet B and H2O2 Are Potent Inducers of Vascular Endothelial Growth Factor Expression in Cultured Keratinocytes

Brauchle, M. A., Funk, J. O., Kind, P., & Werner, S. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.36.21793 · Cited by 158 · see citing works

Induction of antigen-specific immunosuppression by CD95L cDNA-transfected 'killer' dendritic cells

Matsue, H., Matsue, K., Walters, M., Okumura, K., Yagita∥, H., & Takashima, A. (1999) · Nature Medicine · doi:10.1038/11375 · Cited by 157 · see citing works

Successive generation of antigen-presenting, dendritic cell lines from murine epidermis.

Xu, S., Ariizumi, K., Càceres‐Dittmar, G., Edelbaum, D., Hashimoto, K., Bergstresser, P. R., & Takashima, A. (1995) · The Journal of Immunology · doi:10.4049/jimmunol.154.6.2697 · Cited by 153 · see citing works

Localization of DNA damage and its role in altered antigen-presenting cell function in ultraviolet-irradiated mice

Vink, A., Strickland, F., Bucana, C., Cox, P., Roza, L., Yarosh, D. B., & Kripke, M. (1996) · Journal of Experimental Medicine · doi:10.1084/jem.183.4.1491 · Cited by 153 · see citing works

The inhibition of antigen-presenting activity of dendritic cells resulting from UV irradiation of murine skin is restored by in vitro photorepair of cyclobutane pyrimidine dimers.

Vink, A., Moodycliffe, A., Shreedhar, V., Ullrich, S. E., Roza, L., Yarosh, D. B., & Kripke, M. (1997) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.94.10.5255 · Cited by 152 · see citing works

Overexpression of vascular permeability factor (VPF/VEGF) and its endothelial cell receptors in delayed hypersensitivity skin reactions.

Brown, L. F., Olbricht, S. M., Berse, B., Jackman, R. W., Matsueda, G. R., Tognazzi, K., Manseau, E. J., Dvorak, H. F., & Water, L. V. D. (1995) · The Journal of Immunology · doi:10.4049/jimmunol.154.6.2801 · Cited by 150 · see citing works

Molecular Regulation of UVB-Induced Cutaneous Angiogenesis

Bielenberg, D. R., Bucana, C. D., Sànchez, R., Donawho, C. K., Kripke, M. L., & Fidler, I. J. (1998) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.1998.00378.x · Cited by 141 · see citing works

DNA damage enhances melanogenesis

Eller (1996) · Medical Entomology and Zoology · Cited by 139 · see citing works

DETECTION OF CYCLOBUTANE THYMINE DIMERS IN DNA OF HUMAN CELLS WITH MONOCLONAL ANTIBODIES RAISED AGAINST A THYMINE DIMER‐ CONTAINING TETRANUCLEOTIDE

Roza, L., Kj, V. D. W., MacFarlane, S. J., Lohman, P. H. M., & Baan, R. A. (1988) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1988.tb02873.x · Cited by 136 · see citing works

Sunscreens and T4N5 Liposomes Differ in Their Ability to Protect Against Ultraviolet-Induced Sunburn Cell Formation, Alterations of Dendritic Epidermal Cells, and Local Suppression of Contact Hypersensitivity

Wolf, P., Cox, P., Yarosh, D. B., & Kripke, M. L. (1995) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12612828 · Cited by 127 · see citing works

Immune stimulation by an antisense oligomer complementary to the rev gene of HIV-1

Branda, R. F., Moore, A. L., Mathews, L., McCormack, J. J., & Zon, G. (1993) · Biochemical Pharmacology · doi:10.1016/0006-2952(93)90014-n · Cited by 119 · see citing works

Involvement of Cytokines, DNA Damage, and Reactive Oxygen Intermediates in Ultraviolet Radiation-Induced Modulation of Intercellular Adhesion Molecule-1 Expression

Krutmann, J., & Grewe, M. (1995) · Journal of Investigative Dermatology · doi:10.1038/jid.1995.14 · Cited by 118 · see citing works

Intratumoral injection of oligonucleotides to the NFκB binding site inhibits cachexia in a mouse tumor model

Kawamura, I., Morishita, R., Tomita, N., Lacey, E., Aketa, M., Tsujimoto, S., Manda, T., Tomoi, M., Kida, I., Higaki, J., et al. (1999) · Gene Therapy · doi:10.1038/sj.gt.3300819 · Cited by 117 · see citing works

Immune Recognition of Foreign DNA

Klinman, D. M., Verthelyi, D. I., Takeshita, F., & Ishii, K. J. (1999) · Immunity · doi:10.1016/s1074-7613(00)80087-4 · Cited by 116 · see citing works

Impact of UVB Radiation on the Epidermal Cytokine Network

Takashima, A., & Bergstresser, P. R. (1996) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1996.tb03054.x · Cited by 116 · see citing works

Oligodeoxynucleotides Containing Palindrome Sequences with Internal 5′-CpG-3′ Act Directly on Human NK and Activated T Cells to Induce IFN-γ Production In Vitro

Iho, S., Yamamoto, T., Takahashi, T., & Yamamoto, S. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.163.7.3642 · Cited by 114 · see citing works

Oligodeoxynucleotides containing palindrome sequences with internal 5'-CpG-3' act directly on human NK and activated T cells to induce IFN-gamma production in vitro.

Iho, S., Yamamoto, T., Takahashi, T., & Yamamoto, S. (1999) · PubMed · Cited by 110 · see citing works

Oligonucleotide Adjuvants for T Helper 1 (Th1)–specific Vaccination

Carson, D. A., & Raz, E. (1997) · The Journal of Experimental Medicine · doi:10.1084/jem.186.10.1621 · Cited by 105 · see citing works

Quantitative analysis of the immunopotency of genetically transfected dendritic cells

Timares, L., Takashima, A., & Johnston, S. A. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.22.13147 · Cited by 93 · see citing works

Effects of physicochemical agents on murine epidermal Langerhans cells and Thy-1-positive dendritic epidermal cells.

Aberer, W., Romani, N., Elbe, A., & Stingl, G. (1986) · The Journal of Immunology · doi:10.4049/jimmunol.136.4.1210 · Cited by 85 · see citing works

c-rel regulation of IL-2 gene expression may be mediated through activation of AP-1.

Shapiro, V. S., Mollenauer, M. N., Greene, W. C., & Weiss, A. (1996) · The Journal of Experimental Medicine · doi:10.1084/jem.184.5.1663 · Cited by 77 · see citing works

Decoy Administration of NF- κ B into the Subarachnoid Space for Cerebral Angiopathy

Ono, S., Date, I., Onoda, K., Shiota, T., Ohmoto, T., Ninomiya, Y., Asari, S., & Morishita, R. (1998) · Human Gene Therapy · doi:10.1089/hum.1998.9.7-1003 · Cited by 72 · see citing works

T cell-mediated terminal maturation of dendritic cells: loss of adhesive and phagocytotic capacities

Kitajima, T., Càceres‐Dittmar, G., Tapia, F. J., Jester, J. V., Bergstresser, P. R., & Takashima, A. (1996) · The Journal of Immunology · doi:10.4049/jimmunol.157.6.2340 · Cited by 71 · see citing works

PHOTOBIOLOGY SCHOOL

Kripke, M. L. (1990) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1990.tb08703.x · Cited by 71 · see citing works

DNA double strand breaks in epidermal cells cause immune suppression in vivo and cytokine production in vitro.

O'Connor, A., Nishigori, C., Yarosh, D. B., Alas, L., Kibitel, J., Burley, L., Cox, P., Bucana, C., Ullrich, S. E., & Kripke, M. (1996) · Journal of Immunology · doi:10.4049/jimmunol.157.1.271 · Cited by 51 · see citing works

Ultraviolet B radiation sensitizes a murine epidermal dendritic cell line (XS52) to undergo apoptosis upon antigen presentation to T cells.

Kitajima, T., Ariizumi, K., Bergstresser, P., & Takashima, A. (1996) · Journal of Immunology · doi:10.4049/jimmunol.157.8.3312 · Cited by 40 · see citing works

In vivo activation of mouse dendritic epidermal T cells in sites of contact dermatitis

Kamiński, M., Bergstresser, P. R., & Takashima, A. (1993) · European Journal of Immunology · doi:10.1002/eji.1830230748 · Cited by 29 · see citing works

Ibuprofen in the Treatment of UV-B-Induced Inflammation

Stern, R. S. (1985) · Archives of Dermatology · doi:10.1001/archderm.1985.01660040092018 · Cited by 12 · see citing works

Darwin deal marks growth of link-ups for gene companies

Lehrman, S. (1994) · Nature · doi:10.1038/371546b0 · Cited by 6 · see citing works

Targeting Inflammatory Pathways for Prevention and Therapy of Cancer: Short-Term Friend, Long-Term Foe

Aggarwal, B. B., Vijayalekshmi, R. V., & Sung, B. (2009) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-08-0149 · Cited by 795 · see citing works

Ultraviolet radiation and skin aging: roles of reactive oxygen species, inflammation and protease activation, and strategies for prevention of inflammation‐induced matrix degradation – a review

Pillai, S., Oresajo, C., & Hayward, J. (2005) · International Journal of Cosmetic Science · doi:10.1111/j.1467-2494.2004.00241.x · Cited by 706 · see citing works

Photoaging: mechanisms and repair

Rabe, J. H., Mamelak, A. J., McElgunn, P. J. S., Morison, W. L., & Sauder, D. N. (2006) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2005.05.010 · Cited by 610 · see citing works

Ultraviolet light induced injury: Immunological and inflammatory effects

Clydesdale, G. J., Dandie, G. W., & Muller, H. K. (2001) · Immunology and Cell Biology · doi:10.1046/j.1440-1711.2001.01047.x · Cited by 582 · see citing works

Blockade of NF-κB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis

Huang, S., Pettaway, C. A., Uehara, H., Bucana, C. D., & Fidler, I. J. (2001) · Oncogene · doi:10.1038/sj.onc.1204535 · Cited by 556 · see citing works

The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism

Abeyama, K., Stern, D. M., Ito, Y., Kawahara, K., Yoshimoto, Y., Tanaka, M., Uchimura, T., Ida, N., Yamazaki, Y., Yamada, S., et al. (2005) · Journal of Clinical Investigation · doi:10.1172/jci22782 · Cited by 547 · see citing works

Nuclear factor-kappa B and cancer: its role in prevention and therapy

Bharti, A. C., & Aggarwal, B. B. (2002) · Biochemical Pharmacology · doi:10.1016/s0006-2952(02)01154-1 · Cited by 512 · see citing works

CD39 is the dominant Langerhans cell–associated ecto-NTPDase: Modulatory roles in inflammation and immune responsiveness

Mizumoto, N., Kumamoto, T., Robson, S. C., Sévigny, J., Matsue, H., Enjyoji, K., & Takashima, A. (2002) · Nature Medicine · doi:10.1038/nm0402-358 · Cited by 327 · see citing works

Photochemoprevention of ultraviolet B signaling and photocarcinogenesis

Afaq, F., Adhami, V. M., & Mukhtar, H. (2005) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2004.07.019 · Cited by 310 · see citing works

Activation of the Nuclear Factor κB Pathway by Astrocyte Elevated Gene-1: Implications for Tumor Progression and Metastasis

Emdad, L., Sarkar, D., Su, Z.-Z., Randolph, A. L., Boukerche, H., Valerie, K. C., & Fisher, P. B. (2006) · Cancer Research · doi:10.1158/0008-5472.can-05-3029 · Cited by 277 · see citing works

The Pathogenesis of Pterygium: Current Concepts and Their Therapeutic Implications

Chui, J. J. Y., Girolamo, N. D., Wakefield, D., & Coroneo, M. T. (2008) · The Ocular Surface · doi:10.1016/s1542-0124(12)70103-9 · Cited by 277 · see citing works

The UV response of the skin: a review of the MAPK, NFκB and TNFα signal transduction pathways

Muthusamy, V., & Piva, T. J. (2010) · Archives of Dermatological Research · doi:10.1007/s00403-009-0994-y · Cited by 265 · see citing works

Light, including ultraviolet

Maverakis, E. M., Miyamura, Y., Bowen, M. P., Correa, G., Ono, Y., & Goodarzi, H. (2009) · Journal of Autoimmunity · doi:10.1016/j.jaut.2009.11.011 · Cited by 252 · see citing works

VEGF expression in human macrophages is NF-κB-dependent: studies using adenoviruses expressing the endogenous NF-κB inhibitor IκBα and a kinase-defective form of the IκB kinase 2

Kiriakidis, S., Andreakos, E., Monaco, C. G., Foxwell, B. M. J., Feldmann, M., & Paleolog, E. M. (2003) · Journal of Cell Science · doi:10.1242/jcs.00286 · Cited by 235 · see citing works

TRANSCRIPTIONAL AND POST-TRANSCRIPTIONAL CONTROL OF GENE EXPRESSION IN INFLAMMATION

Kracht, M., & Saklatvala, J. (2002) · Cytokine · doi:10.1006/cyto.2002.0895 · Cited by 228 · see citing works

Ultraviolet B Regulation of Transcription Factor Families: Roles of Nuclear Factor-kappa B (NF-κB) and Activator Protein-1 (AP-1) in UVB-Induced Skin Carcinogenesis

Cooper, S., & Bowden, G. T. (2007) · Current Cancer Drug Targets · doi:10.2174/156800907780809714 · Cited by 205 · see citing works

Role and Therapeutic Targeting of the PI3K/Akt/mTOR Signaling Pathway in Skin Cancer: A Review of Current Status and Future Trends on Natural and Synthetic Agents Therapy

Chamcheu, J. C., Roy, T., Uddin, M. B., Banang‐Mbeumi, S., Chamcheu, R. N., Walker, A. L., Liu, Y., & Huang, S. (2019) · Cells · doi:10.3390/cells8080803 · Cited by 203 · see citing works

Nutraceuticals for Skin Care: A Comprehensive Review of Human Clinical Studies

Pérez-Sánchez, A., Barrajón‐Catalán, E., Herranz‐López, M., & Micol, V. (2018) · Nutrients · doi:10.3390/nu10040403 · Cited by 187 · see citing works

Involvement of NF-κB signalling in skin physiology and disease

Bell, S. A., Degitz, K., Quirling, M., Jilg, N., Page, S., & Brand, K. (2003) · Cellular Signalling · doi:10.1016/s0898-6568(02)00080-3 · Cited by 173 · see citing works

Development of a Peptide Inhibitor of Hyaluronan-Mediated Leukocyte Trafficking

Mummert, M. E., Mohamadzadeh, M., Mummert, D. I., Mizumoto, N., & Takashima, A. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.6.769 · Cited by 166 · see citing works

Protein kinases and transcription factors activation in response to UV-radiation of skin: implications for carcinogenesis

López-Camarillo, C., Aréchaga Ocampo, E., López Casamichana, M., Pérez-Plasencia, C., Álvarez-Sánchez, E., & Marchat, L. A. (2011) · International Journal of Molecular Sciences · doi:10.3390/ijms13010142 · Cited by 165 · see citing works

The PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds

Roy, T., Boateng, S. T., Uddin, M. B., Banang‐Mbeumi, S., Yadav, R. K., Bock, C. R., Folahan, J. T., Siwe‐Noundou, X., Walker, A. L., King, J. A. C., et al. (2023) · Cells · doi:10.3390/cells12121671 · Cited by 173 · see citing works

Contact dermatitis

Scheinman, P. L., Vocanson, M., Thyssen, J. P., Johansen, J. D., Nixon, R. L., Dear, K., Botto, N. C., Morot, J., & Goldminz, A. M. (2021) · Nature Reviews Disease Primers · doi:10.1038/s41572-021-00271-4 · Cited by 163 · see citing works

Protective Effects of Novel Derivatives of Vitamin D3 and Lumisterol Against UVB-Induced Damage in Human Keratinocytes Involve Activation of Nrf2 and P53 Defense Mechanisms

Chaiprasongsuk, A., Janjetovic, Z., Kim, T.-K., Jarrett, S. G., D'Orazio, J. A., Holick, M. F., Tang, E. K. Y., Tuckey, R. C., Panich, U., Li, W., et al. (2019) · Redox Biology · doi:10.1016/j.redox.2019.101206 · Cited by 146 · see citing works

Selective Blockade of NF-κB Activity in Airway Immune Cells Inhibits the Effector Phase of Experimental Asthma

Desmet, C. J., Gosset, P., Pajak, B., Cataldo, D. D., Bentires‐Alj, M., Lekeux, P. M., & Bureau, F. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.9.5766 · Cited by 137 · see citing works

Expression of inflammasome proteins and inflammasome activation occurs in human, but not in murine keratinocytes

Sand, J., Haertel, E., Biedermann, T., Contassot, E., Ernst Reichmann, A., French, L. E., Werner, S., & Beer, H. (2018) · Cell Death and Disease · doi:10.1038/s41419-017-0009-4 · Cited by 130 · see citing works

Extracellular high mobility group box chromosomal protein 1 is a coupling factor for hypoxia and inflammation in arthritis

Hamada, T., Torikai, M., Kuwazuru, A., Tanaka, M., Horai, N., Fukuda, T., Yamada, S., Nagayama, S., Hashiguchi, K., Sunahara, N., et al. (2008) · Arthritis & Rheumatism · doi:10.1002/art.23729 · Cited by 130 · see citing works

Divergent gene regulation and growth effects by NF-κB in epithelial and mesenchymal cells of human skin

Hinata, K., Gervin, A. M., Zhang, J. Y., & Khavari, P. A. (2003) · Oncogene · doi:10.1038/sj.onc.1206198 · Cited by 130 · see citing works

Biological consequences of cyclobutane pyrimidine dimers

Vink, A. A., & Roza, L. (2001) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/s1011-1344(01)00245-7 · Cited by 122 · see citing works

Photoprotection of UV-Irradiated Human Skin: An Antioxidative Combination of Vitamins E and C, Carotenoids, Selenium and Proanthocyanidins

Greul, A., Grundmann, J., Heinrich, F., Pfitzner, I., Bernhardt, J. H., Ambach, A., Biesalski, H. K., & Gollnick, H. P. M. (2002) · Skin Pharmacology and Physiology · doi:10.1159/000064534 · Cited by 124 · see citing works

Photoaging of the skin

Ichihashi, M., Ando, H., Yoshida, M., Niki, Y., & Matsui, M. S. (2009) · Anti-aging Medicine · doi:10.3793/jaam.6.46 · Cited by 121 · see citing works

Bombesin stimulates nuclear factor kappa B activation and expression of proangiogenic factors in prostate cancer cells.

Levine, L., Lucci, J. A., Pazdrak, B., Cheng, J. Z., Guo, Y., Townsend, C. M., & Hellmich, M. R. (2003) · PubMed · Cited by 122 · see citing works

Nuclear factor kappa B—molecular biomedicine: the next generation

Celec, P. (2004) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2003.12.015 · Cited by 113 · see citing works

NF‐κB activity blockade impairs the angiogenic potential of human pancreatic cancer cells

Xiong, H. Q., Abbruzzese, J. L., Lin, E. H., Wang, L., Zheng, L., & Xie, K. (2003) · International Journal of Cancer · doi:10.1002/ijc.11562 · Cited by 110 · see citing works

Skin cancer: role of ultraviolet radiation in carcinogenesis

Mancebo, S. E., & Wang, S. Q. (2014) · Reviews on Environmental Health · doi:10.1515/reveh-2014-0041 · Cited by 106 · see citing works

Prostaglandin E2 is required for ultraviolet B-induced skin inflammation via EP2 and EP4 receptors

Kabashima, K., Nagamachi, M., Honda, T., Nishigori, C., Miyachi, Y., TOKURA, Y., & Narumiya, S. (2006) · Laboratory Investigation · doi:10.1038/labinvest.3700491 · Cited by 99 · see citing works

Prevention of the ultraviolet B-mediated skin photoaging by a nuclear factor κB inhibitor, parthenolide

Tanaka, K., Hasegawa, J., Asamitsu, K., & Okamoto, T. (2005) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.105.088674 · Cited by 96 · see citing works

Supreme EnLIGHTenment: Damage Recognition and Signaling in the Mammalian UV Response

Herrlich, P. A., Karin, M., & Weiß, C. (2008) · Molecular Cell · doi:10.1016/j.molcel.2008.01.001 · Cited by 93 · see citing works

Hair follicles serve as local reservoirs of skin mast cell precursors

Kumamoto, T., Shalhevet, D., Matsue, H., Mummert, M. E., Ward, B. R., Jester, J. V., & Takashima, A. (2003) · Blood · doi:10.1182/blood-2003-02-0449 · Cited by 93 · see citing works

Selective IKK2 inhibitor IMD0354 disrupts NF-κB signaling to suppress corneal inflammation and angiogenesis

Lennikov, A., Mirabelli, P., Mukwaya, A., Schaupper, M., Thangavelu, M., Lachota, M., Ali, Z., Jensen, L. D., & Lagali, N. (2018) · Angiogenesis · doi:10.1007/s10456-018-9594-9 · Cited by 88 · see citing works

p38 Mitogen-Activated Protein Kinase Inhibitor Protects the Epidermis Against the Acute Damaging Effects of Ultraviolet Irradiation by Blocking Apoptosis and Inflammatory Responses

Hildesheim, J., Awwad, R. T., & Fornace, A. J. (2004) · Journal of Investigative Dermatology · doi:10.1111/j.1523-1747.2004.22229.x · Cited by 86 · see citing works

Rubus idaeus L. (red raspberry) blocks UVB-induced MMP production and promotes type I procollagen synthesis via inhibition of MAPK/AP-1, NF-κβ and stimulation of TGF-β/Smad, Nrf2 in normal human dermal fibroblasts

Gao, W., Wang, Y., Hwang, E., Lin, P., Bae, J., Seo, S. A., Yan, Z., & Yi, T. (2018) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2018.06.007 · Cited by 85 · see citing works

Molecular imaging of the transcription factor NF-κB, a primary regulator of stress response

Carlsen, H., Alexander, G., Austenaa, L. M. I., Ebihara, K., & Blomhoff, R. (2004) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2004.02.024 · Cited by 80 · see citing works

Tiron Inhibits UVB-Induced AP-1 Binding Sites Transcriptional Activation on MMP-1 and MMP-3 Promoters by MAPK Signaling Pathway in Human Dermal Fibroblasts

Lu, J., Guo, J.-H., Tu, X.-L., Zhang, C., Zhao, M., Zhang, Q.-W., & Gao, F.-H. (2016) · PLOS ONE · doi:10.1371/journal.pone.0159998 · Cited by 79 · see citing works

Keratinocytes in epidermal immune responses

Steinhoff, M. S., Brzoska, T., & Luger, T. A. (2001) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/01.all.0000011062.60720.e3 · Cited by 79 · see citing works

The microtubule-depolymerizing agent ansamitocin P3 programs dendritic cells toward enhanced anti-tumor immunity

Martin, K., Müller, P., Schreiner, J., Prince, S. S., Lardinois, D., Heinzelmann-Schwarz, V. A., Thommen, D. S., & Zippelius, A. (2014) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-014-1565-4 · Cited by 78 · see citing works

Molecular changes during skin aging and wound healing after fractional ablative photothermolysis

Helbig, D., & Paasch, U. (2011) · Skin Research and Technology · doi:10.1111/j.1600-0846.2010.00477.x · Cited by 75 · see citing works

Constitutive and tumor necrosis factor-α-induced activation of nuclear factor-κB in adenomyosis and its inhibition by andrographolide

Li, B., Chen, M., Liu, X., & Guo, S. (2013) · Fertility and Sterility · doi:10.1016/j.fertnstert.2013.04.028 · Cited by 78 · see citing works

The Role of Interleukin-1 in Inflammatory and Malignant Human Skin Diseases and the Rationale for Targeting Interleukin-1 Alpha

Bou-Dargham, M. J., Khamis, Z. I., Cognetta, A. B., & Sang, Q. A. (2016) · Medicinal Research Reviews · doi:10.1002/med.21406 · Cited by 75 · see citing works

The protective effect of 18β-Glycyrrhetinic acid against UV irradiation induced photoaging in mice

Kong, S.-Z., Chen, H.-M., Yu, X.-T., Zhang, X., Feng, X.-X., Kang, X.-H., Li, W.-J., Huang, N., Luo, H., & Su, Z.-R. (2015) · Experimental Gerontology · doi:10.1016/j.exger.2014.12.008 · Cited by 73 · see citing works

Skin photo-protection with phytochemicals against photo-oxidative stress, photo-carcinogenesis, signal transduction pathways and extracellular matrix remodeling—An overview

Garg, C., Sharma, H., & Garg, M. (2020) · Ageing Research Reviews · doi:10.1016/j.arr.2020.101127 · Cited by 70 · see citing works

Autocrine VEGF mediates the antiapoptotic effect of CD154 on CLL cells

Farahani, M., Treweeke, A. T., Toh, C., Till, K. J., Harris, R. J., Cawley, J. C., Zuzel, M., & Chen, H. (2005) · Leukemia · doi:10.1038/sj.leu.2403631 · Cited by 70 · see citing works

Co-activation of ERK, NF-κB, and GADD45β in Response to Ionizing Radiation

Wang, T., Hu, Y., Dong, S., Fan, M., Tamae, D., Ozeki, M., Gao, Q., Gius, D. R., & Li, J. J. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m410982200 · Cited by 64 · see citing works

Pterygium—The Good, the Bad, and the Ugly

Acker, S. I. V., den Bogerd, B. V., Haagdorens, M. K. C., Siozopoulou, V., Dhubhghaill, S. N., Pintelon, I., & Koppen, C. (2021) · Cells · doi:10.3390/cells10071567 · Cited by 64 · see citing works

Tumor Necrosis Factor α-Mediated Induction of Interleukin 17C in Human Keratinocytes Is Controlled by Nuclear Factor κB

Johansen, C., Riis, J. L., Gedebjerg, A., Kragballe, K., & Iversen, L. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.240671 · Cited by 64 · see citing works

Estrogen Enhances Angiogenesis through a Pathway Involving Platelet-Activating Factor-Mediated Nuclear Factor-κB Activation

Seo, K. H., Lee, H.-S., Jung, B., Ko, H.-M., Choi, J., Park, S. J., Choi, I.-H., Lee, H.-K., & Im, S. (2004) · Cancer Research · doi:10.1158/0008-5472.can-03-2774 · Cited by 61 · see citing works

7-Hydroxycoumarin prevents UVB-induced activation of NF-κB and subsequent overexpression of matrix metalloproteinases and inflammatory markers in human dermal fibroblast cells

Karthikeyan, R., Kanimozhi, G., Prasad, N. R., Balupillai, A., Muthusamy, G., Shanmugham, M., & Gunaseelan, S. (2016) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2016.04.027 · Cited by 61 · see citing works

Combined Effects of Carotenoids and Polyphenols in Balancing the Response of Skin Cells to UV Irradiation

Calniquer, G., Khanin, M., Ovadia, H., Linnewiel‐Hermoni, K., Stepensky, D., Trachtenberg, A., Sedlov, T., Braverman, O., Levy, J., & Sharoni, Y. (2021) · Molecules · doi:10.3390/molecules26071931 · Cited by 59 · see citing works

Practical and experimental consideration of sun protection in dermatology

Ting, W. W., Vest, C. D., & Sontheimer, R. D. (2003) · International Journal of Dermatology · doi:10.1046/j.1365-4362.2003.01867.x · Cited by 58 · see citing works

Restoring chemotherapy and hormone therapy sensitivity by parthenolide in a xenograft hormone refractory prostate cancer model

Shanmugam, R., Jayaprakasan, V., Gökmen‐Polar, Y., Kelich, S. L., Miller, K. D., Yip-Schneider, M., Liang Cheng, C., Bhat‐Nakshatri, P., Sledge, G. W., Nakshatri, H., et al. (2006) · The Prostate · doi:10.1002/pros.20482 · Cited by 56 · see citing works

Epigenetics changes associated to environmental triggers in autoimmunity

Cañas, C. A., Cañas, F., Bonilla‐Abadía, F., Ospina, F. E., & Tobón, G. J. (2015) · Autoimmunity · doi:10.3109/08916934.2015.1086996 · Cited by 49 · see citing works

The toll-like receptor 3 pathway in homeostasis, responses to injury and wound repair

Ramnath, D., Powell, E. E., Scholz, G. M., & Sweet, M. J. (2016) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2016.08.014 · Cited by 49 · see citing works

The Nuclear-Factor κB Pathway Is Activated in Pterygium

Siak, J. J. K., Ng, S. L., Seet, L., Beuerman, R. W., & Tong, L. H. T. (2010) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.10-5735 · Cited by 48 · see citing works

Topical Imiquimod Treatment Prevents UV-Light Induced Loss of Contact Hypersensitivity and Immune Tolerance

Thatcher, T. H., Luzina, I. G., Fishelevich, R., Tomai, M. A., Miller, R. L., & Gaspari, A. A. (2006) · Journal of Investigative Dermatology · doi:10.1038/sj.jid.5700167 · Cited by 47 · see citing works

8-Oxo-2′-deoxyguanosine ameliorates UVB-induced skin damage in hairless mice by scavenging reactive oxygen species and inhibiting MMP expression

Lee, J., Ko, S.-H., Ye, S., & Chung, M.-H. (2013) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2013.01.010 · Cited by 46 · see citing works

Short-chain aldehyde-derived ligands for RAGE and their actions on endothelial cells

Yamamoto, Y., Yonekura, H., Watanabe, T., Sakurai, S., Li, H., Harashima, A., Myint, K. M., Osawa, M., Takeuchi, A., Takeuchi, M., et al. (2007) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2007.01.030 · Cited by 44 · see citing works

Transglutaminase 2 mediates UV-induced skin inflammation by enhancing inflammatory cytokine production

Lee, S.-J., Lee, K. B., Son, Y. H., Shin, J., Lee, J.-H., Kim, H.-J., Hong, A.-Y., Bae, H. W., Kwon, M.-A., Lee, W. J., et al. (2017) · Cell Death and Disease · doi:10.1038/cddis.2017.550 · Cited by 44 · see citing works

HMGB‐1 induces IL‐6 production in human synovial fibroblasts through c‐Src, Akt and NF‐κB pathways

Hou, C., Fong, Y., & Tang, C. (2010) · Journal of Cellular Physiology · doi:10.1002/jcp.22541 · Cited by 42 · see citing works

Local therapy for cutaneous and systemic lupus erythematosus: practical and theoretical considerations

Ting, W. W., & Sontheimer, R. D. (2001) · Lupus · doi:10.1191/096120301667674688 · Cited by 41 · see citing works

Essential role for platelet‐activating factor‐induced NF‐κB activation in macrophage‐derived angiogenesis

Seo, K. H., Ko, H., Choi, J. H., Jung, H. H., Chun, Y. H., Choi, I., Lee, H., & Im, S. (2004) · European Journal of Immunology · doi:10.1002/eji.200424957 · Cited by 39 · see citing works

Xeroderma Pigmentosum: General Aspects and Management

Piccione, M., Fortina, A. B., Ferri, G., Andolina, G., Beretta, L., Cividini, A., Marni, E. D., Caroppo, F., Citernesi, U., & Liddo, R. D. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11111146 · Cited by 42 · see citing works

Activation of MAPK Signaling Pathway and NF-κB Activation in Pterygium and Ipsilateral Pterygium-Free Conjunctival Specimens

Torres, J., Enríquez‐de‐Salamanca, A., Fernández, I., Ares, M. T. R., Quadrado, M. J., Murta, J., del Castillo, J. M. B., Stern, M. E., & Calonge, M. (2011) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.10-6673 · Cited by 36 · see citing works

UV induces VEGF through a TNF‐α‐independent pathway

Kosmadaki, M. G., Yaar, M., Arble, B. L., & Gilchrest, B. A. (2003) · The FASEB Journal · doi:10.1096/fj.02-0379fje · Cited by 36 · see citing works

HMGB-1 induces cell motility and α5β1 integrin expression in human chondrosarcoma cells

Tang, C., Keng, Y.-T., & Liu, J. (2012) · Cancer Letters · doi:10.1016/j.canlet.2012.02.014 · Cited by 33 · see citing works

Anti-photoaging properties of the phosphodiesterase 3 inhibitor cilostazol in ultraviolet B-irradiated hairless mice

Kim, H. N., Gil, C. H., Kim, Y. R., Shin, H. K., & Choi, B. T. (2016) · Scientific Reports · doi:10.1038/srep31169 · Cited by 32 · see citing works

Inhibitory effect of fucoidan on TNF-α-induced inflammation in human retinal pigment epithelium cells

Lee, S., Lee, E. J., Lee, G. M., Yun, J.-H., & Yoo, W. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1162934 · Cited by 32 · see citing works

The two faces of metallothionein in carcinogenesis: photoprotection against UVR-induced cancer and promotion of tumour survival

McGee, H. M., Woods, G. M., Bennett, B., & Chung, R. S. (2010) · Photochemical & Photobiological Sciences · doi:10.1039/b9pp00155g · Cited by 31 · see citing works

Topical Administration of Manuka Oil Prevents UV-B Irradiation-Induced Cutaneous Photoaging in Mice

Kwon, O. S., Jung, S. H., & Yang, B. S. (2013) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2013/930857 · Cited by 32 · see citing works

The NLRP1 Inflammasome Pathway Is Silenced in Cutaneous Squamous Cell Carcinoma

Sand, J., Fenini, G., Grossi, S., Hennig, P., Filippo, M. D., Levesque, M. P., Werner, S., French, L. E., & Beer, H. (2019) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2019.01.025 · Cited by 29 · see citing works

Potential Photoprotective Effect of Dietary Corn Silk Extract on Ultraviolet B-Induced Skin Damage

Kim, Y.-H., Cho, A., Kwon, S.-A., Kim, M., Song, M., Han, H. W., Shin, E.-J., Park, E., & Lee, S.-M. (2019) · Molecules · doi:10.3390/molecules24142587 · Cited by 31 · see citing works

In vivo transfection of a cis element ‘decoy’ against signal transducers and activators of transcription 6 (STAT6)-binding site ameliorates IgE-mediated late-phase reaction in an atopic dermatitis mouse model

Yokozeki, H., Wu, M., Sumi, K., AWAD, S. S., Satoh, T., Katayama, I., Takeda, K., Akira, S., Kaneda, Y., & Nishioka, K. (2004) · Gene Therapy · doi:10.1038/sj.gt.3302341 · Cited by 30 · see citing works

Analgesic potential of PF-06372865, an α2/α3/α5 subtype-selective GABAA partial agonist, in humans

van Amerongen, G., Siebenga, P. S., Gurrell, R., Dua, P., Whitlock, M., Gorman, D. N., Okkerse, P., Hay, J. L., Butt, R. P., & Groeneveld, G. J. (2019) · British Journal of Anaesthesia · doi:10.1016/j.bja.2018.12.006 · Cited by 30 · see citing works

Prolongation of liver allograft survival by dendritic cells modified with NF-κB decoy oligodeoxynucleotides

Xu, M. (2004) · World Journal of Gastroenterology · doi:10.3748/wjg.v10.i16.2361 · Cited by 30 · see citing works

Effects of estradiol on VEGF and bFGF by Akt in endometrial cancer cells are mediated through the NF-κB pathway

Zhang, J., Song, H., Lu, Y., Chen, H., Jiang, S., & Li, L. (2016) · Oncology Reports · doi:10.3892/or.2016.4888 · Cited by 29 · see citing works

The TGFβ1 pathway is required for NFκB dependent gene expression in mouse keratinocytes

Hogan, K. A., Ravindran, A., Podolsky, M. A., & Glick, A. B. (2013) · Cytokine · doi:10.1016/j.cyto.2013.09.004 · Cited by 29 · see citing works

Morinda citrifolia Linn. (Rubiaceae) leaf extracts mitigate UVB-induced erythema

West, B. J., Deng, S., Palu, '. K., & Jensen, C. J. (2009) · Journal of Natural Medicines · doi:10.1007/s11418-009-0327-7 · Cited by 29 · see citing works

Involvement of hyaluronan in epidermal Langerhans cell maturation and migration in vivo

Mummert, D. I., Takashima, A., Ellinger, L., & Mummert, M. E. (2003) · Journal of Dermatological Science · doi:10.1016/s0923-1811(03)00160-9 · Cited by 29 · see citing works

Picea mariana polyphenolic extract inhibits phlogogenic mediators produced by TNF-α-activated psoriatic keratinocytes: Impact on NF-κB pathway

García‐Pérez, M., Allaeys, I., Rusu, D., Pouliot, R., Janežić, T. S., & Poubelle, P. E. (2013) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2013.10.034 · Cited by 28 · see citing works

Influence of GSTT1 and GSTM1 Genotypes on Sunburn Sensitivity

Kerb, R., BROCKMOLLER, J., Schlagenhaufer, R., Sprenger, R., Roots, I., & Brinkmann, U. (2002) · American Journal of PharmacoGenomics · doi:10.2165/00129785-200202020-00007 · Cited by 27 · see citing works

Triamcinolone suppresses retinal vascular pathology via a potent interruption of proinflammatory signal-regulated activation of VEGF during a relative hypoxia

Kim, Y. H., Chung, I. Y., Choi, M., Kim, Y. S., Lee, J. H., Park, C. H., Kang, S. S., Roh, G. S., Choi, W. S., Yoo, J. M., et al. (2007) · Neurobiology of Disease · doi:10.1016/j.nbd.2007.02.002 · Cited by 26 · see citing works

IKKβ Regulates VEGF Expression and Is a Potential Therapeutic Target for Ovarian Cancer as an Antiangiogenic Treatment

Kinose, Y., Sawada, K., Makino, H., Ogura, T., Mizuno, T., Suzuki, N., Fujikawa, T., Morii, E., Nakamura, K., Sawada, I., et al. (2015) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-14-0696 · Cited by 26 · see citing works

Modeling of solar UV-induced photodamage on the hair follicles in human skin organoids

Kim, M.-J., Ahn, H.-J., Kong, D., Lee, S., Kim, D.-H., & Kang, K.-S. (2024) · Journal of Tissue Engineering · doi:10.1177/20417314241248753 · Cited by 25 · see citing works

Corneal NF-κB activity is necessary for the retention of transparency in the cornea of UV-B-exposed transgenic reporter mice

Alexander, G., Carlsen, H., & Blomhoff, R. (2005) · Experimental Eye Research · doi:10.1016/j.exer.2005.09.012 · Cited by 25 · see citing works

Receptors in Skin Ageing and Antiageing Agents

Ghersetich, I., Troiano, M., GIORGI, V. D., & Lotti, T. (2007) · Dermatologic Clinics · doi:10.1016/j.det.2007.06.018 · Cited by 24 · see citing works

Mechanism by which H-2g, a glucose analog of blood group H antigen, mediates angiogenesis

Zhu, K., Amin, M. A., Zha, Y., Harlow, L. A., & Koch, A. E. (2004) · Blood · doi:10.1182/blood-2004-08-3140 · Cited by 24 · see citing works

Ultraviolet Radiation Inhibits Interleukin-2-induced Tyrosine Phosphorylation and the Activation of STAT5 in T Lymphocytes

Kulms, D., & Schwarz, T. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m006372200 · Cited by 24 · see citing works

Nuclear factor-κB decoy oligodeoxynucleotides attenuates ischemia/reperfusion injury in rat liver graft

Xu, M. (2005) · World Journal of Gastroenterology · doi:10.3748/wjg.v11.i44.6960 · Cited by 23 · see citing works

Myotrophin–κB DNA interaction in the initiation process of cardiac hypertrophy

Gupta, S., & Sen, S. (2002) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/s0167-4889(02)00178-7 · Cited by 23 · see citing works

Thread Embedding Acupuncture Inhibits Ultraviolet B Irradiation-Induced Skin Photoaging in Hairless Mice

Kim, Y. J., Kim, H.-N., Shin, M., & Choi, B. (2015) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2015/539172 · Cited by 22 · see citing works

Inhibitory effects of Schisandra chinensis extract on acne-related inflammation and UVB-induced photoageing

Guo, M., Lu, Y., Yang, J.-P., Zhao, X., & Lü, Y. (2016) · Pharmaceutical Biology · doi:10.1080/13880209.2016.1199041 · Cited by 23 · see citing works

A role for NF-KB-dependent gene transactivation in sunburn

Abeyama, K., Eng, W., Jester, J. V., Vink, A. A., Edelbaum, D., Cockerell, C. J., Bergstresser, P. R., & Takashima, A. (2000) · TNO Repository

Enhancement of ultraviolet-induced apoptosis by NF-kappaB decoy oligonucleotides

Yokoyama, S., Nakano, H., Yamazaki, T., Tamai, K., Hanada, K., & Takahashi, G. (2005) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2005.06969.x · Cited by 17 · see citing works

Ultraviolet B radiation activates NF‐κB and induces iNOS expression in HR‐1 hairless mouse skin: Role of IκB kinase‐β

Chang, E., Kundu, J. K., Liu, L., Shin, J.-W., & Surh, Y. (2011) · Molecular Carcinogenesis · doi:10.1002/mc.20646 · Cited by 33 · see citing works

Translation Regulation of UV-induced Transcription Factor NF-κB and Oncogene COX-2

László, C. (2009) · OhioLink ETD Center (Ohio Library and Information Network)

Role of phosphorylated p50-NF-?B in the ultraviolet response of mouse skin

P�rez, P., Page, A., & Jorcano, J. (2000) · Molecular Carcinogenesis · doi:10.1002/(sici)1098-2744(200004)27:4 · Cited by 21 · see citing works