The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Health care costs associated with depressive and anxiety disorders in primary care
Abstract
OBJECTIVE: The authors examined the overall health care costs associated with depression and anxiety among primary care patients. METHOD: Of 2,110 consecutive primary care patients in a health maintenance organization, 1,962 were screened with the 12-item General Health Questionnaire. A stratified random sample of 615 patients were selected for further diagnostic assessment; 373 of these patients completed the Composite International Diagnostic Interview at baseline and 328 were reassessed 12 months later. Computerized cost records were used to calculate total health care costs for the 6-month period surrounding the baseline assessment and a similar period surrounding the follow-up assessment. Cost accounting data were available for 327 patients at baseline and for 206 patients at both assessments. RESULTS: Primary care patients with DSM-III-R anxiety or depressive disorders at baseline had markedly higher baseline costs ($2,390) than patients with subthreshold disorders ($1,098) and those with no anxiety or depressive disorder ($1,397). Large cost differences persisted after adjustment for medical morbidity. Cost differences reflected higher utilization of general medical services rather than higher mental health treatment costs. Although most patients with baseline anxiety or depressive disorders showed significant improvement, longitudinal analyses did not show any clear relationship between change in psychiatric diagnosis and change in health care cost. CONCLUSIONS: Among primary care patients, anxiety and depressive disorders are associated with markedly higher health care costs even after adjustment for medical comorbidity. In this small sample, improvement in depression over 1 year was not clearly associated with decreases in cost.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Elevated anxiety predicts the overutilization of oncology care [10] and primary care [11, 12]”
In the citing paper
“This proposed mechanism is supported by the documented association between anxiety, depression and higher health care utilisation [58].”
Citations
Cites
Robins, L. N. (1988) · Archives of General Psychiatry · doi:10.1001/archpsyc.1988.01800360017003 · Cited by 2,909
The functioning and well-being of depressed patients. Results from the Medical Outcomes Study
Wells, K. B. (1989) · JAMA · doi:10.1001/jama.262.7.914 · Cited by 2,826
The Functioning and Well-being of Depressed Patients: Results From the Medical Outcomes Study
Wells, K. B. (1989) · JAMA · doi:10.1001/jama.1989.03430070062031 · Cited by 2,130
The de Facto US Mental and Addictive Disorders Service System
Regier, D. A. (1993) · Archives of General Psychiatry · doi:10.1001/archpsyc.1993.01820140007001 · Cited by 1,988
A chronic disease score from automated pharmacy data
Korff, M. V., Wagner, E. H., & Saunders, K. W. (1992) · Journal of Clinical Epidemiology · doi:10.1016/0895-4356(92)90016-g · Cited by 962
Service utilization and social morbidity associated with depressive symptoms in the community
Johnson, J. (1992) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1992.03480110054033 · Cited by 726
Disability and Depression Among High Utilizers of Health Care: A Longitudinal Analysis
Von Korff, M. (1992) · Archives of General Psychiatry · doi:10.1001/archpsyc.1992.01820020011002 · Cited by 523
Distressed high utilizers of medical care
Katon, W., Von Korff, M., Lin, E., Lipscomb, P., Russo, J., Wagner, E., & Polk, E. (1990) · General Hospital Psychiatry · doi:10.1016/0163-8343(90)90002-t · Cited by 512
The Prevalence of Psychiatric Disorders in a Primary Care Practice
Barrett, J. E. (1988) · Archives of General Psychiatry · doi:10.1001/archpsyc.1988.01800360048007 · Cited by 490
The Course of Depression in Adult Outpatients: Results From the Medical Outcomes Study
Wells, K. B. (1992) · Archives of General Psychiatry · doi:10.1001/archpsyc.1992.01820100032007 · Cited by 475
Research works printed but not linked: 5
- Depression Guideline Panel, 1993, Md, US Department of Health and Human Services, Public Health Service
- 1989, Scheidemandel P: The Coverage Catalog
- Sharfstein, 1993, Stoline AM
- Simon G, 1992, Psychiatr Med, 10, 49
- 1978, England
Cited by
Sorted by citations
DiMatteo, M. R., Lepper, H. S., & Croghan, T. W. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.14.2101 · Cited by 4,177
Validity of the brief patient health questionnaire mood scale (PHQ-9) in the general population
Martin, A., Rief, W., Klaiberg, A., & Braehler, E. (2006) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2005.07.003 · Cited by 1,379
“Depression is associated with severe impairment in physical, social and role functioning, and with higher health care utilization [1,2].”
BackgroundThe Journal of Mental Health Policy and Economics
(2006) · The Journal of Mental Health Policy and Economics · doi:10.1002/(issn)1099-176x · Cited by 1,255
LOWE, B. (2004) · Journal of Affective Disorders · doi:10.1016/s0165-0327(02)00237-9 · Cited by 1,060
“…associated with high levels of personal suffering, increased disability days, and elevated risk of cardiovascular mortality and suicide (Wells et al., 1989; Broadhead et al., 1990; Ormel et al., 1994; Simon et al., 1995; Frasure-Smith et al., 2000; Penninx et al., 2001; Posternak and Miller, 2001).”
BackgroundCharlson, M. E., Charlson, R. E., Peterson, J. C., Marinopoulos, S. S., Briggs, W. M., & Hollenberg, J. P. (2008) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2008.01.006 · Cited by 894
A Multifaceted Intervention to Improve Treatment of Depression in Primary Care
Katon, W. (1996) · Archives of General Psychiatry · doi:10.1001/archpsyc.1996.01830100072009 · Cited by 835
Egede, L. E., Zheng, D., & Simpson, K. (2002) · Diabetes Care · doi:10.2337/diacare.25.3.464 · Cited by 816
Screening psychischer Störungen mit dem “Gesundheitsfragebogen für Patienten (PHQ-D)“
Gräfe, K., Zipfel, S., Herzog, W., & Löwe, B. (2004) · Diagnostica · doi:10.1026/0012-1924.50.4.171 · Cited by 805
Generalized anxiety disorder: prevalence, burden, and cost to society
Wittchen, H.-U. (2002) · Depression and Anxiety · doi:10.1002/da.10065 · Cited by 733
“Primary care patients with DSM-III-R anxiety or depressive disorders have been reported to have markedly higher associated costs ($2,390/patient) than patients with subthreshold disorders ($1,098/patient) or those with no anxiety or depressive disorder ($1397/ patient) [Simon et al., 1995].”
Unützer, J. (1997) · JAMA · doi:10.1001/jama.1997.03540440052032 · Cited by 697
Prevalence, burden, and treatment of insomnia in primary care
(1997) · American Journal of Psychiatry · doi:10.1176/ajp.154.10.1417 · Cited by 694
“Diagnostic classification according to DSM-IV criteria was based on coding of data from the Composite International Diagnostic Interview by means of algorithms using criteria previously described (12, 18).”
MethodSelf-citationWang, P. S., Berglund, P., & Kessler, R. C. (2000) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2000.9908044.x · Cited by 686
“sector , defined as seeing a medical doctor other than a psychiatrist in any setting for a mental or emotional problem; (2) psychiatrist, mental health specialty sector , defined as seeing a psychiatrist for treatment of a mental health problem; (3) nonpsychiatrist, mental health specialty”
BackgroundMethodStepped Collaborative Care for Primary Care Patients With Persistent Symptoms of Depression
Katon, W. J., Korff, M. V., Lin, E., Simon, G., Walker, E., Unützer, J., Bush, T. M., Russo, J. E., & Ludman, E. J. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.12.1109 · Cited by 658
“There has been substantial evidence demonstrating that depression is associated with multiple unexplained medical symptoms,(3) impairment in functioning and quality of life,(2,4) and high medical costs.(5,6) There is also accumulating evidence that more intensive, organized treatment that integrates mental health prac…”
BackgroundSelf-citationPrevalence and clinical course of depression: a review
Richards, D. (2011) · Clinical Psychology Review · doi:10.1016/j.cpr.2011.07.004 · Cited by 623
Validity of the patient health questionnaire-9 for depression screening and diagnosis in East Africa
Gelaye, B., Williams, M. A., Lemma, S., Deyessa, N., Bahretibeb, Y., Shibre, T., Wondimagegn, D., Lemenhe, A., Fann, J. R., Stoep, A. V., et al. (2013) · Psychiatry Research · doi:10.1016/j.psychres.2013.07.015 · Cited by 548
“and increased mortality (Broadhead et al., 1990; Lowe et al., 2004; Simon et al., 1995).”
BackgroundClinical handbook of mindfulness
(2009) · doi:10.1007/978-0-387-09593-6 · Cited by 543
Scott, K. M., Bruffaerts, R., Tsang, A., Ormel, J., Alonso, J., Angermeyer, M. C., Benjet, C., Bromet, E., de Girolamo, G., de Graaf, R., et al. (2007) · Journal of Affective Disorders · doi:10.1016/j.jad.2007.01.015 · Cited by 529
“…and public health significance in their impact on role impairment (Sullivan et al., 1997; Kessler et al., 2003), treatment costs and adherence (Simon et al., 1995; Ciechanowski et al., 2000) and premature mortality risk (Harris and Barraclough, 1998; van Melle et al., 2004; Zhang et al.,…”
BackgroundSelf-citationMental Disorders and Use of Cardiovascular Procedures After Myocardial Infarction
Druss, B. G. (2000) · JAMA · doi:10.1001/jama.283.4.506 · Cited by 541
Depression in Women: Implications for Health Care Research
Weissman, M. M., & Olfson, M. (1995) · Science · doi:10.1126/science.7638596 · Cited by 525
Health Care Costs of Primary Care Patients With Recognized Depression
Simon, G. E. (1995) · Archives of General Psychiatry · doi:10.1001/archpsyc.1995.03950220060012 · Cited by 520
Self-citationThompson, C., Kinmonth, A., Stevens, L., Pevele, R., Stevens, A., Ostler, K., Pickering, R., Baker, N., Henson, A., Preece, J., et al. (2000) · The Lancet · doi:10.1016/s0140-6736(99)03171-2 · Cited by 489
Han, C., Jo, S. A., Kwak, J.-H., Pae, C.-U., Steffens, D., Jo, I., & Park, M. H. (2008) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2007.08.006 · Cited by 465
“Depressive symptoms are frequently associated with severe impairment in physical and social function and with higher health care use [1,2].”
BackgroundTreating Major Depression in Primary Care Practice
Schulberg, H. C., Katon, W. J., Simon, G. E., & Rush, A. J. (1998) · Archives of General Psychiatry · doi:10.1001/archpsyc.55.12.1121 · Cited by 455
Self-citationMelfi, C. A., Chawla, A. J., Croghan, T. W., Hanna, M. P., Kennedy, S., & Sredl, K. (1998) · Archives of General Psychiatry · doi:10.1001/archpsyc.55.12.1128 · Cited by 409
“Furthermore, most patients do not currently receive the recommended length of continuation treatment.(14-16) These issues suggest the need to look more closely at the effects of completing the continuation phase of treatment on relapse or recurrence of depression.”
BackgroundHermann, B. P., Seidenberg, M., & Bell, B. D. (2000) · Epilepsia · doi:10.1111/j.1528-1157.2000.tb01522.x · Cited by 407
The Direct and Indirect Costs of Untreated Insomnia in Adults in the United States
Ozminkowski, R. J., Wang, S. S., & Walsh, J. K. (2007) · SLEEP · doi:10.1093/sleep/30.3.263 · Cited by 403
Cost-of-illness studies of depression
Luppa, M., Heinrich, S., Angermeyer, M. C., König, H., & Riedel-Heller, S. G. (2006) · Journal of Affective Disorders · doi:10.1016/j.jad.2006.07.017 · Cited by 369
Mental disorders among persons with heart disease — results from World Mental Health surveys
Ormel, J., Korff, M. V., Burger, H., Scott, K. M., Demyttenaere, K., Huang, Y., Posada-Villa, J., Lepine, J. P., Angermeyer, M. C., Levinson, D., et al. (2007) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2007.03.009 · Cited by 360
“Depression–diabetes comorbidity is associated with adverse diabetes outcomes, functional disability, increased mortality, and increased health care costs [10–15].”
BackgroundSelf-citationRandomized Trial of a Depression Management Program in High Utilizers of Medical Care
Katzelnick, D. J. (2000) · Archives of Family Medicine · doi:10.1001/archfami.9.4.345 · Cited by 331
“Use of general medical services by depressed primary care patients is 50% to 100% higher than utilization by similar patients without depressive illness.(6,7) The economic burden of depression in primary care (in terms of increased health care utilization and lost productivity) vastly exceeds the resources currently d…”
BackgroundPrieto, J. M., Blanch, J., Atala, J., Carreras, E., Rovira, M., Cirera, E., & Gastó, C. (2002) · Journal of Clinical Oncology · doi:10.1200/jco.2002.07.101 · Cited by 329
Lagerveld, S. E., Bültmann, U., Franche, R. ‐., van Dijk, F. J. H., Vlasveld, M. C., Feltz-Cornelis, C. M. V. D., Bruinvels, D. J., Huijs, J. J. J. M., Blonk, R. W. B., van der Klink, J. J. L., et al. (2010) · Journal of Occupational Rehabilitation · doi:10.1007/s10926-009-9224-x · Cited by 324
“Several strategies can be considered (1) Improve knowledge of health providers about diagnosis of depression: In many countries, there is a notable underdiagnosis of depression in primary care patients [55–59] and absence of diagnosis will delay obtaining treatment and prolong episode duration.”
Osório, F. D. L., Mendes, A. V., Crippa, J. A. S., & Loureiro, S. R. (2009) · Perspectives In Psychiatric Care · doi:10.1111/j.1744-6163.2009.00224.x · Cited by 321
Katon, W. J., Unützer, J., Wells, K. B., & Jones, L. (2010) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2010.04.001 · Cited by 298
“Patients withmajor depression in primary care systemswere also shown to have high numbers of medically unexplained symptoms [3], a greater degree of comorbid medical illness [4], as much or more functional impairment as patients with other common medical disorders such as diabetes or heart disease [5], andup to twofol…”
BackgroundSomatization and Medicalization in the Era of Managed Care
BARSKY, A. J. (1995) · JAMA · doi:10.1001/jama.1995.03530240041038 · Cited by 290
Depression's Vicious Scree: Self-Propagating and Erosive Processes in Depression Chronicity
Joiner, T. E. (2000) · Clinical Psychology Science and Practice · doi:10.1093/clipsy.7.2.203 · Cited by 301
Blanchard, L. T., Gurka, M. J., & Blackman, J. A. (2006) · PEDIATRICS · doi:10.1542/peds.2005-2606 · Cited by 284
“26 The possible explanations for this increase include (1) a broadened definition of autism, (2) heightened awareness of the condition, (3) an actual increase in the number of cases, or (4) any combination of these factors.”
BackgroundInfluentialHoge, C. W., Lesikar, S. E., Guevara, R. E., Lange, J., Brundage, J. F., Engel, C. C., Messer, S. C., & Orman, D. T. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.9.1576 · Cited by 273
The combined dexamethasone/CRH test as a potential surrogate marker in depression
Ising, M., Kunzel, H. E., Binder, E. B., Nickel, T., Modell, S., & Holsboer, F. (2005) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2005.03.014 · Cited by 275
“When considering direct medical costs and indirect economic losses due to missed work days and decreased income, depression takes a major share of the overall healthcare expenditures in industrialized countries (Simon et al., 1995; Thompson and Richardson, 1999).”
BackgroundInfluentialThe Cost–Utility of Screening for Depression in Primary Care
Valenstein, M., Vijan, S., Zeber, J. E., Boehm, K., & Buttar, A. (2001) · Annals of Internal Medicine · doi:10.7326/0003-4819-134-5-200103060-00007 · Cited by 268
“Depressive disorders are associated with higher general medical costs (11), and early quasi-experimental studies suggested that medical costs were reduced after psychiatric treatment, particularly among inpatients (105, 106, 135).”
BackgroundThe prevalence and burden of subthreshold generalized anxiety disorder: a systematic review
Haller, H., Cramer, H., Lauche, R., Gass, F., & Dobos, G. J. (2014) · BMC Psychiatry · doi:10.1186/1471-244x-14-128 · Cited by 267
“Of these, 21 studies [22-42] were excluded because they reported outcome data only for mixed subthreshold diagnoses, for subthreshold diagnoses other than GAD or because they contained data analyzed in already included articles.”
BackgroundRecovery from depression, work productivity, and health care costs among primary care patients
Simon, G. E., Revicki, D. A., Heiligenstein, J. H., Grothaus, L. C., VonKorff, M., Katon, W. J., & Hylan, T. R. (2000) · General Hospital Psychiatry · doi:10.1016/s0163-8343(00)00072-4 · Cited by 267
“We previously attempted to examine the relationship between change in depression and change in health care costs in one of the primary care studies described above, but the sample size was not sufficient to detect even moderately large effects [12].”
BackgroundSelf-citationOrmel, J., Kempen, G. I. J. M., Deeg, D. J. H., Brilman, E. I., van Sonderen, E., & Relyveld, J. (1998) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1998.tb01011.x · Cited by 260
Self-citationMaternal Depressive Symptoms and Adherence to Therapy in Inner-City Children With Asthma
Bartlett, S. J., Krishnan, J. A., Riekert, K. A., Butz, A. M., Malveaux, F. J., & Rand, C. S. (2004) · PEDIATRICS · doi:10.1542/peds.113.2.229 · Cited by 247
Depression and Service Utilization in Elderly Primary Care Patients
Luber, M. P., Meyers, B. S., Williams-Russo, P. G., Hollenberg, J. P., DiDomenico, T. N., Charlson, M. E., & Alexopoulos, G. S. (2001) · American Journal of Geriatric Psychiatry · doi:10.1097/00019442-200105000-00009 · Cited by 248
Diabetes complications and depression as predictors of health service costs
Simon, G. E., Katon, W. J., Lin, E. H. B., Ludman, E. J., VonKorff, M., Ciechanowski, P. S., & Young, B. A. (2005) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2005.04.008 · Cited by 243
“Our central findings are broadly consistent with a large body of research on the association between depression and use of health services [9,23–25] and a smaller body of research specific to diabetes [12,14,15].”
ResultSelf-citationPassive and In-Situ assessment of mental and physical well-being using mobile sensors
Rabbi, M., Ali, S., Choudhury, T., & Berke, E. (2011) · Proceedings of the 13th international conference on Ubiquitous computing · doi:10.1145/2030112.2030164 · Cited by 243
“Depression, a common psychiatric disorder, has a prevalence of 5-25% [23, 24] and contributes significantly to the cost of healthcare [25, 26].”
BackgroundA Computer-Administered Telephone Interview to Identify Mental Disorders
Kobak, K. A. (1997) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1997.03550110043034 · Cited by 238
Health Care Costs Associated With Posttraumatic Stress Disorder Symptoms in Women
Walker, E. A., Katon, W. J., Russo, J. E., Ciechanowski, P. S., Newman, E., & Wagner, A. W. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.4.369 · Cited by 234
Achieving Guidelines for the Treatment of Depression in Primary Care
Lin, E. H. B., Katon, W. J., Simon, G. E., Korff, M. V., Bush, T. M., Rutter, C. M., Saunders, K. W., & Walker, A. (1997) · Medical Care · doi:10.1097/00005650-199708000-00008 · Cited by 228
Self-citationGoetzel, R. Z., Ozminkowski, R. J., Sederer, L. I., & Mark, T. L. (2002) · Journal of Occupational and Environmental Medicine · doi:10.1097/00043764-200204000-00012 · Cited by 236
Clinical Assessment of Axis I Psychiatric Morbidity in Chronic Epilepsy: A Multicenter Investigation
Jones, J. E., Hermann, B. P., Barry, J. J., Gilliam, F. G., Kanner, A. M., & Meador, K. J. (2005) · Journal of Neuropsychiatry · doi:10.1176/jnp.17.2.172 · Cited by 274
Donohue, J. M., & Pincus, H. A. (2007) · PharmacoEconomics · doi:10.2165/00019053-200725010-00003 · Cited by 214
“depression.[40,44,45,47-52,54,63] • When reviewing studies on the cost effectiveness Simon et al.”
BackgroundRollman, B. L., Belnap, B. H., Mazumdar, S., Houck, P. R., Zhu, F., Gardner, W., Reynolds, C. F., Schulberg, H. C., & Shear, M. K. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.12.1332 · Cited by 197
Strategies to Improve the Management of Depression in Primary Care
Unützer, J., & Park, M. (2012) · Primary Care Clinics in Office Practice · doi:10.1016/j.pop.2012.03.010 · Cited by 205
Cost-effectiveness of Systematic Depression Treatment for High Utilizers of General Medical Care
Simon, G. E., Manning, W. G., Katzelnick, D. J., Pearson, S. D., Henk, H. J., & Helstad, C. P. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.2.181 · Cited by 199
Self-citationHealthcare Costs Associated with Depression in Medically Ill Fee‐for‐Service Medicare Participants
Unützer, J., Schoenbaum, M., Katon, W. J., Fan, M., Pincus, H. A., Hogan, D., & Taylor, J. (2009) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2008.02134.x · Cited by 197
Liu, S.-I., Yeh, Z.-T., Huang, H.-C., Sun, F.-J., Tjung, J.-J., Hwang, L.-C., Shih, Y.-H., & Yeh, A. W.-C. (2011) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2010.04.013 · Cited by 192
“Depression is associated with severe impairment in physical, social, and role functioning and with more frequent use of health care [1-3].”
BackgroundQuality Adjusted Life Years in Older Adults With Depressive Symptoms and Chronic Medical Disorders
Unützer, J., Patrick, D. L., Diehr, P. H., Simon, G., Grembowski, D. E., & Katon, W. J. (2000) · International Psychogeriatrics · doi:10.1017/s1041610200006177 · Cited by 193
Self-citationDepression: cost-of-illness studies in the international literature, a review
Berto, P., D'Ilario, D., Ruffo, P., Virgilio, R. D., & Rizzo, F. (2000) · The Journal of Mental Health Policy and Economics · doi:10.1002/1099-176x(200003)3:1 · Cited by 191
Incontinence Severity and Major Depression in Incontinent Women
Melville, J., Delaney, K. M., Newton, K. M., & Katon, W. J. (2005) · Obstetrics and Gynecology · doi:10.1097/01.aog.0000173985.39533.37 · Cited by 189
Mental disorders among persons with diabetes—Results from the World Mental Health Surveys
Lin, E. H. B., & Korff, M. V. (2008) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2008.06.007 · Cited by 201
Grace, S. L., Abbey, S. E., Irvine, J., Shnek, Z. M., & Stewart, D. E. (2004) · Psychotherapy and Psychosomatics · doi:10.1159/000080387 · Cited by 189
“Some studies show that patients with anxiety utilize medical services to a greater degree than do patients without anxiety [”
BackgroundRevicki, D. A. (1998) · Journal of Affective Disorders · doi:10.1016/s0165-0327(97)00117-1 · Cited by 180
Outcomes of recognized and unrecognized depression in an international primary care study
Simon, G. E., Goldberg, D. P., Tiemens, B. G., & Üstün, T. B. (1999) · General Hospital Psychiatry · doi:10.1016/s0163-8343(98)00072-3 · Cited by 176
“Depression is also associated with a large burden of lost productivity [3,5,6] and increased use of general health services [7,8].”
BackgroundSelf-citationMelville, J., Walker, E., Katon, W. J., Lentz, G. M., Miller, J. L., & Fenner, D. E. (2002) · American Journal of Obstetrics and Gynecology · doi:10.1067/mob.2002.124839 · Cited by 173
Somatization, somatosensory amplification, attribution styles and illness behaviour: A review
Duddu, V., Isaac, M., & Chaturvedi, S. K. (2006) · International Review of Psychiatry · doi:10.1080/09540260500466790 · Cited by 173
Evolving Models of Behavioral Health
Collins, C., Hewson, D. L., Munger, R. L., & Wade, T. L. (2010) · doi:10.1599/evolvingcare2010 · Cited by 172
Thyroid peroxidase antibodies during gestation are a marker for subsequent depression postpartum
Kuijpens, J. L. P., Vader, H., Drexhage, H., Wiersinga, W. M., van Son, M. J. M., & Pop, V. J. M. (2001) · European Journal of Endocrinology · doi:10.1530/eje.0.1450579 · Cited by 169
Creed, F. H., Morgan, R., Fiddler, M., Marshall, S., Guthrie, E., & House, A. O. (2002) · Psychosomatics · doi:10.1176/appi.psy.43.4.302 · Cited by 167
Population-based care of depression: Effective disease management strategies to decrease prevalence
Katon, W. J., Korff, M. V., Lin, E. H. B., Unützer, J., Simon, G., Walker, E., Ludman, E. J., & Bush, T. M. (1997) · General Hospital Psychiatry · doi:10.1016/s0163-8343(97)00016-9 · Cited by 164
Self-citationEffects of anxiety and depression on 5-year mortality in 5057 patients referred for exercise testing
Herrmann‐Lingen, C., Brand-Driehorst, S., Buss, U., & Rüger, U. (2000) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(99)00086-0 · Cited by 163
Finley, P. R., Rens, H. R., Pont, J. T., Gess, S. L., Louie, C., Bull, S. A., Lee, J. Y., & Bero, L. A. (2003) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1592/phco.23.10.1175.32760 · Cited by 162
Chronic Care Costs In Managed Care
Fishman, P. A., Korff, M. V., Lozano, P., & Hecht, J. A. (1997) · Health Affairs · doi:10.1377/hlthaff.16.3.239 · Cited by 158
“All adults 258,015 2,006 (6,058) 924 (2,701) 2,346 (4,827) 3,992 (8,990) 7,019 (13,131)”
BackgroundGut Microbiota in Anxiety and Depression: Unveiling the Relationships and Management Options
Kumar, A., Pramanik, J., Goyal, N., Chauhan, D., Sivamaruthi, B. S., Prajapati, B. G., & Chaiyasut, C. (2023) · Pharmaceuticals · doi:10.3390/ph16040565 · Cited by 174
“addition to the adverse effects on the individuals affected, these disorders place a significant financial strain on society due to high healthcare costs [14,15].”
BackgroundJobes, D. A., Wong, S. A., Conrad, A. K., Drozd, J. F., & Neal‐Walden, T. A. (2005) · Suicide and Life-Threatening Behavior · doi:10.1521/suli.2005.35.5.483 · Cited by 148
Helmchen, H., & Linden, M. (2000) · Comprehensive Psychiatry · doi:10.1016/s0010-440x(00)80001-2 · Cited by 146
Vasiliadis, H., Dionne, P.-A., Préville, M., Gentil, L., Berbiche, D., & Latimer, E. A. (2013) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2012.12.016 · Cited by 140
Depressive Symptoms, Bone Loss, and Fractures in Postmenopausal Women
Spangler, L., Scholes, D., Brunner, R. L., Robbins, J. A., Reed, S. D., Newton, K. M., Melville, J., & LaCroix, A. Z. (2008) · Journal of General Internal Medicine · doi:10.1007/s11606-008-0525-0 · Cited by 140
Outcome of anxiety and depressive disorders in primary care
Ronalds, C., Creed, F. H., Stone, K., Webb, S., & Tomenson, B. (1997) · The British Journal of Psychiatry · doi:10.1192/bjp.171.5.427 · Cited by 132
Henk, H. J. (1996) · Archives of General Psychiatry · doi:10.1001/archpsyc.1996.01830100045006 · Cited by 130
Hulme, P. A. (2000) · Child Abuse & Neglect · doi:10.1016/s0145-2134(00)00200-3 · Cited by 128
Efficacy of newer medications for treating depression in primary care patients
Mulrow, C. D., Williams, J. W., Chiquette, E., Aguilar, C., Noël, P. H., Lee, S., Cornell, J. E., & Stamm, K. E. (2000) · The American Journal of Medicine · doi:10.1016/s0002-9343(99)00316-2 · Cited by 128
Care for Depression in HMO Patients Aged 65 and Older
Unützer, J., Simon, G., Belin, T. R., Datt, M., Katon, W. J., & Patrick, D. L. (2000) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2000.tb06882.x · Cited by 126
Self-citationThe Economic, Public Health, and Caregiver Burden of Late-life Depression
Zivin, K., Wharton, T., & Rostant, O. S. (2013) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2013.08.008 · Cited by 125
Psychiatric co‐morbidity is associated with increased risk of surgery in Crohn's disease
Ananthakrishnan, A. N., Gainer, V. S., Perez, R. G., Cai, T., Cheng, S. ‐., Savova, G., Chen, P., Szolovits, P., Xia, Z., De Jager, P. L., et al. (2013) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.12195 · Cited by 122
Stark, K. D., & Laurent, J. (2001) · Journal of Clinical Child & Adolescent Psychology · doi:10.1207/s15374424jccp3004_11 · Cited by 129
Associação entre sintomas depressivos e funcionamento social em cuidados primários à saúde
Fleck, M. P. D. A., Lima, A. F. B. D. S., Louzada, S., Schestasky, G., Henriques, A. A., Borges, V. R., & Camey, S. A. (2002) · Revista de Saúde Pública · doi:10.1590/s0034-89102002000400008 · Cited by 121
Weisberg, R. B., DYCK, I. R., Culpepper, L., & Keller, M. B. (2007) · American Journal of Psychiatry · doi:10.1176/ajp.2007.164.2.276 · Cited by 120
Psychosomatic Medicine: A New Psychiatric Subspecialty
Gitlin, D. F. (2004) · Academic Psychiatry · doi:10.1176/appi.ap.28.1.4 · Cited by 119
Depression in primary care: linking clinical and systems strategies
Pincus, H. A., Pechura, C. M., Elinson, L., & Pettit, A. R. (2001) · General Hospital Psychiatry · doi:10.1016/s0163-8343(01)00165-7 · Cited by 118
“Compared to nondepressed patients, depressed patients use health care services three times as frequently [14], visit the emergency room seven times more frequently [15], and have twice the overall medical costs, even after controlling for severity of comorbid general medical conditions [ 16 ].”
BackgroundJohannsen, M., Nissen, E. R., Lundorff, M., & O'Toole, M. S. (2022) · Clinical Psychology Review · doi:10.1016/j.cpr.2022.102156 · Cited by 116
Patient Gender Differences in the Diagnosis of Depression in Primary Care
Bertakis, K. D., Helms, L. J., Callahan, E. J., Azari, R. S., Leigh, P., & Robbins, J. A. (2001) · Journal of Women s Health & Gender-Based Medicine · doi:10.1089/15246090152563579 · Cited by 117
Byrne, M. L., O’Brien-Simpson, N. M., Reynolds, E. C., Walsh, K. A., Laughton, K., Waloszek, J. M., Woods, M. J., Trinder, J., & Allen, N. B. (2013) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2013.08.010 · Cited by 144
“However, when non-detectable levels were included as zero, salivary levels of CRP, interleukin (IL)-2, IL-12p70, and interferon (IFN)-γ correlated with their serum counterparts.”
InfluentialWolf, N. J., & Hopko, D. R. (2008) · Clinical Psychology Review · doi:10.1016/j.cpr.2007.04.004 · Cited by 116
Depression and Healthcare Service Utilization in Patients with Cancer
Mausbach, B. T., & Irwin, S. A. (2016) · Psycho-Oncology · doi:10.1002/pon.4133 · Cited by 104
Benjamins, M. R. (2006) · Journal of Behavioral Medicine · doi:10.1007/s10865-005-9035-2 · Cited by 114
“, 1997), both of which have been shown to influence the use of health services (Koenig et al., 1989; Simon et al., 1995).”
BackgroundRamsawh, H. J., Chavira, D. A., & Stein, M. B. (2010) · Archives of Pediatrics & Adolescent Medicine · doi:10.1001/archpediatrics.2010.170 · Cited by 110
Keuroghlian, A. S., Frankenburg, F. R., & Zanarini, M. C. (2013) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2013.06.012 · Cited by 118
“…between major depressive disorder (MDD) and higher rates of both general medical illness and increased health services utilization, (Druss et al., 2000; Katon, 2003; Simon et al., 1995a; Simon et al., 1995b) we also controlled for potential confounding effects of time-varying J Psychiatr Res.”
BackgroundHandbook of Complex Occupational Disability Claims
Schultz, I. Z., & Gatchel, R. J. (2005) · Springer eBooks · doi:10.1007/0-387-28919-4 · Cited by 112
Garrard, J. M., Rolnick, S. J., Nitz, N., Luepke, L., Jackson, J., Fischer, L. R., Leibson, C. L., Bland, P. C., Heinrich, R. L., & Waller, L. A. (1998) · The Journals of Gerontology Series A · doi:10.1093/gerona/53a.2.m92 · Cited by 108
“Of those who are diagnosed and/or treated for minor or major depression, at least half are managed only by primary care physicians (9-13).”
Background
Metadata
- Authors
- Simon, G. E., Ormel, J., VonKorff, M., & Barlow, W. E.
- Affiliations
- Group Health Cooperative (US)
- Venue
- American Journal of Psychiatry
- Published
- 1995-03-01
- Volume
- 152
- Issue
- 3
- Pages
- 352-357
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W1666540207
- Cited by
- 555
- References
- 19
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 2 · 2023: 7 · 2022: 12 · 2021: 11 · 2020: 5 · 2019: 14 · 2018: 12 · 2017: 11 · 2016: 10 · 2015: 13 · 2014: 11 · 2013: 19 · 2012: 19
- FWCI
- 46.20
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion)
- Funders
- National Institutes of Health (1r03mh047765-01)
- National Institute of Mental Health (R01MH051338, MH-47765, MH51338)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- depression, anxiety disorders, health care costs, primary care, comorbidities, health maintenance organizations, General Health Questionnaire, Composite International Diagnostic Interview, health care utilization
- MeSH terms
- Adolescent, Adult, Aged, Anxiety Disorders, Depressive Disorder, Female, Follow-Up Studies, Health Services, Humans, Male, Middle Aged, Primary Health Care, Psychiatric Status Rating Scales, Comorbidity, Treatment Outcome, Health Care Costs
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review