Cited by 276Psychotherapy Techniques and ApplicationsTreatment of Major DepressionMental Health Treatment and Access

The DOI matches its Crossref record; 51 of the 51 references it cites were found in a registry or an index.

Treatments for Later-Life Depressive Conditions: A Meta-Analytic Comparison of Pharmacotherapy and Psychotherapy

Pinquart, Martin, Duberstein, Paul R., Lyness, Jeffrey M.·2006·American Journal of Psychiatry

DOI 10.1176/ajp.2006.163.9.1493

Open this paper in CoChat — free account

Abstract

OBJECTIVE: To improve interventions for depressed older adults, data are needed on the comparative effects of pharmacotherapy versus psychotherapy. Given that most older adults with clinically significant depressive symptoms do not have major depression, data on treatments for minor depression and dysthymia are especially needed. METHOD: Meta-analysis was used to integrate the results of 89 controlled studies of treatments focused on acute major depression (37 studies) and other depressive disorders (52 studies conducted with mixed diagnostic groups, including patients with major depression, minor depression, and dysthymia). A total of 5,328 older adults received pharmacotherapy or psychotherapy in these studies. RESULTS: Clinician-rated depression scores improved, on average, by 0.80 standard deviation (SD) units; self-rated depression scores improved by 0.76 SD units. Clinician-rated depression improved by 0.69 SD units in pharmacotherapeutic studies and by 1.09 SD units in psychotherapeutic studies. Self-rated depression improved by 0.62 SD units and 0.83 SD units, respectively. An interesting finding was the stronger improvements in clinician-rated depression among control subjects participating in medication studies, compared to those in psychotherapeutic studies. CONCLUSIONS: Available treatments for depression work, with effect sizes that are moderate to large. Comparisons of psychotherapy and pharmacotherapy must be interpreted with caution, in part because medication studies are more likely to use a credible active placebo, which may lead to smaller adjusted effect sizes in medication studies. Given that psychotherapy and pharmacotherapy did not show strong differences in effect sizes, treatment choice should be based on other criteria, such as contraindications, treatment access, or patient preferences.

Integrity signals

Registry

Crossref · 10.1176/ajp.2006.163.9.1493

Cites

51 of 51 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

A rating scale for depression
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817
Statistical Methods for Rates and Proportions
Fleiss, J. L., Levin, B., & Paik, M. C. (2003) · Wiley Series in Probability and Statistics · doi:10.1002/0471445428 · Cited by 18,646
Development and validation of a geriatric depression screening scale: a preliminary report
Yesavage, J. A., Brink, T. L., Rose, T. L., Lum, O., Huang, V., Adey, M., & Leirer, V. O. (1982) · Journal of Psychiatric Research · doi:10.1016/0022-3956(82)90033-4 · Cited by 15,025
A new depression scale designed to be sensitive to change
Montgomery, S. A., & Åsberg, M. (1979) · British Journal of Psychiatry · doi:10.1192/bjp.134.4.382 · Cited by 13,962
A power primer.
Cohen, J. (1992) · Psychological Bulletin · doi:10.1037//0033-2909.112.1.155 · Cited by 8,771
Distribution Theory for Glass's Estimator of Effect Size and Related Estimators
Hedges, L. V. (1981) · Journal of Educational Statistics · doi:10.2307/1164588 · Cited by 5,695
Meta-Analytic Procedures for Social Research.
Metcalfe, A., & Rosenthal, R. (1994) · Journal of the Royal Statistical Society Series D (The Statistician) · doi:10.2307/2348600 · Cited by 4,249
Meta-analysis in social research
(1982) · Evaluation and Program Planning · doi:10.1016/0149-7189(82)90011-8 · Cited by 3,896
Statistical Methods for Rates and Proportions, 2nd ed
GROVE, W. A. (1981) · American Journal of Psychiatry · doi:10.1176/ajp.138.12.1644-a · Cited by 3,756
Fixed-and random-effects models in meta-analysis.
Hedges, L. V., & Vevea, J. L. (1998) · Psychological Methods · doi:10.1037/1082-989x.3.4.486 · Cited by 2,977

Show all 51 references

Research works printed but not linked: 12

10.1001/jama.1997.03550140078045 · DOI
Rokke PD, 1995, J Clin Geropsychol, 1, 243
Dhooper SS, 1993, J Gerontol Soc Work, 20, 87
Agency for Health Care Policy and Research, 1993, Md
Kemp BJ, Gill B: Effects of brief cognitive-behavioral group psychotherapy on older persons with and without disabling illness. Behavior, Health, and Aging 1991-1992
Guaiana G, 2003, Cochrane Database Syst Rev, 2, D004186
Engels GI, 1997, J Clin Geropsychol, 3, 17
Blazer D, 1993, CV Mosby
Beck AT, 1979, Tex
Glass GV, 1981, McGaw B
Rosenthal R, 1991, Calif
10.1037/0033-2909.112.1.155 · DOI · Paper page

Sorted by citations

Depression in Older Adults
Fiske, A., Wetherell, J. L., & Gatz, M. (2009) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.032408.153621 · Cited by 2,353
Screening for Depression in Adults: US Preventive Services Task Force Recommendation Statement
Siu, A. L., and the US Preventive Services Task Force (USPSTF), Bibbins-Domingo, K., Grossman, D. C., Baumann, L. C., Davidson, K. W., Ebell, M., García, F. A. R., Gillman, M., Herzstein, J., et al. (2016) · JAMA · doi:10.1001/jama.2015.18392 · Cited by 1,407
Evidence-based guidelines for treating depressive disorders with antidepressants: A revision of the 2000 British Association for Psychopharmacology guidelines
Anderson, I. M., Ferrier, I. N., Baldwin, R., Cowen, P. J., Howard, L. M., Lewis, G., Matthews, K., McAllister-Williams, H., Peveler, R. C., Scott, J. L., et al. (2008) · Journal of Psychopharmacology · doi:10.1177/0269881107088441 · Cited by 909
Management of Depression in Older Adults: A Review
Kok, R. M., & Reynolds, C. F. (2017) · JAMA · doi:10.1001/jama.2017.5706 · Cited by 890
Evidence-based guidelines for treating depressive disorders with antidepressants: A revision of the 2008 British Association for Psychopharmacology guidelines
Cleare, A., Pariante, C., Young, A., Anderson, I., Christmas, D., Cowen, P., Dickens, C., Ferrier, I., Geddes, J., Gilbody, S., et al. (2015) · Journal of Psychopharmacology · doi:10.1177/0269881115581093 · Cited by 759
Mechanisms and treatment of late-life depression
Alexopoulos, G. S. (2019) · Translational Psychiatry · doi:10.1038/s41398-019-0514-6 · Cited by 592
Screening for Depression in Adults: U.S. Preventive Services Task Force Recommendation Statement
U.S. Preventive Services Task Force* (2009) · Annals of Internal Medicine · doi:10.7326/0003-4819-151-11-200912010-00006 · Cited by 581
The effects of psychotherapy for adult depression are overestimated: a meta-analysis of study quality and effect size
Cuijpers, P., van Straten, A., Bohlmeijer, E., Hollon, S. D., & Andersson, G. (2010) · Psychological Medicine · doi:10.1017/s0033291709006114 · Cited by 533
Waiting list may be a nocebo condition in psychotherapy trials: a contribution from network meta-analysis
Furukawa, T. A., Noma, H., Caldwell, D. M., Honyashiki, M., Shinohara, K., Imai, H., Chen, P., Hunot, V., & Churchill, R. (2014) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12275 · Cited by 521
Self-reported versus clinician-rated symptoms of depression as outcome measures in psychotherapy research on depression: A meta-analysis
Cuijpers, P., Li, J., Hofmann, S. G., & Andersson, G. (2010) · Clinical Psychology Review · doi:10.1016/j.cpr.2010.06.001 · Cited by 383
Effects of psychotherapy and other behavioral interventions on clinically depressed older adults: A meta-analysis
Pinquart, M., Duberstein, P. R., & Lyness, J. M. (2007) · Aging & Mental Health · doi:10.1080/13607860701529635 · Cited by 328
Self-citation
Psychometric Properties of the Beck Depression Inventory—II (BDI-II) Among Community-Dwelling Older Adults
Segal, D. L., Coolidge, F. L., Cahill, B. S., & O'Riley, A. A. (2008) · Behavior Modification · doi:10.1177/0145445507303833 · Cited by 335
Stepped-Care Prevention of Anxiety and Depression in Late Life
Veer-Tazelaar, P. J. V., van Marwijk, H., van Oppen, P., van Hout, H. P. J., van der Horst, H. E., Cuijpers, P. J., Smit, F., & Beekman, A. T. F. (2009) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2008.555 · Cited by 320
Post stroke depression: the sequelae of cerebral stroke
Das, J., & G.K., R. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.04.005 · Cited by 301
The impact of depressive symptoms in early Parkinson disease
Ravina, B. M., Camicioli, R. M., Como, P. G., Marsh, L., Jankovic, J. J., Weintraub, D. A., & Elm, J. J. (2007) · Neurology · doi:10.1212/01.wnl.0000268695.63392.10 · Cited by 301
Outcomes of Minor and Subsyndromal Depression among Elderly Patients in Primary Care Settings
Lyness, J. M., Heo, M., Datto, C. J., Have, T. R. T., Katz, I. R., Drayer, R. A., Reynolds, C. F., Alexopoulos, G. S., & BRUCE, M. L. (2006) · Annals of Internal Medicine · doi:10.7326/0003-4819-144-7-200604040-00008 · Cited by 271
Self-citation
The neurobiology of depression in later-life: Clinical, neuropsychological, neuroimaging and pathophysiological features
Naismith, S. L., Norrie, L. M., Mowszowski, L., & Hickie, I. B. (2012) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2012.05.009 · Cited by 282
Perceived burdensomeness and suicide ideation in older adults
Cukrowicz, K. C., Cheavens, J. S., Van Orden, K. A., Ragain, R. M., & Cook, R. L. (2011) · Psychology and Aging · doi:10.1037/a0021836 · Cited by 267
Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder
MacQUEEN, G. M., Frey, B. N., Ismail, Z., Jaworska, N., Steiner, M. S., Lieshout, R. J. V., Kennedy, S. H., Lam, R. W. M., Milev, R. V., Parikh, S. V., et al. (2016) · The Canadian Journal of Psychiatry · doi:10.1177/0706743716659276 · Cited by 266
The impact of whole-of-diet interventions on depression and anxiety: a systematic review of randomised controlled trials
Opie, R. S., O’Neil, A., Itsiopoulos, C., & Jacka, F. N. (2015) · Public Health Nutrition · doi:10.1017/s1368980014002614 · Cited by 243
Efficacy of Second Generation Antidepressants in Late-Life Depression: A Meta-Analysis of the Evidence
Nelson, J. C., Delucchi, K., & Schneider, L. S. (2008) · The American Journal of Geriatric Psychiatry · doi:10.1097/01.jgp.0000308883.64832.ed · Cited by 230
Psychobiological factors of resilience and depression in late life
Laird, K. T., Krause, B., Funes, C., & Lavretsky, H. (2019) · Translational Psychiatry · doi:10.1038/s41398-019-0424-7 · Cited by 229
Late-Life Depression
Unützer, J. (2007) · New England Journal of Medicine · doi:10.1056/nejmcp073754 · Cited by 223
Biological factors influencing depression in later life: role of aging processes and treatment implications
Szymkowicz, S. M., Gerlach, A., Homiack, D., & Taylor, W. D. (2023) · Translational Psychiatry · doi:10.1038/s41398-023-02464-9 · Cited by 234
Cognitive Behavioral Therapy for Depression in Older People: A Meta‐Analysis and Meta‐Regression of Randomized Controlled Trials
Gould, R. L., Coulson, M., & Howard, R. J. (2012) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2012.04166.x · Cited by 212
Managing depression in older age: psychological interventions
Cuijpers, P., Karyotaki, E., Pot, A. M., Park, M., & Reynolds, C. F. (2014) · Maturitas · doi:10.1016/j.maturitas.2014.05.027 · Cited by 192
Clinical Effectiveness of Individual Cognitive Behavioral Therapy for Depressed Older People in Primary Care: A Randomized Controlled Trial
Serfaty, M. A., Haworth, D., Blanchard, M., Buszewicz, M., Murad, S., & King, M. (2009) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2009.165 · Cited by 190
The Clinical Significance of Subsyndromal Depression in Older Primary Care Patients
Lyness, J. M., Kim, J.-H., Tu, X. M., Conwell, Y., King, D. A., & Caine, E. D. (2007) · American Journal of Geriatric Psychiatry · doi:10.1097/01.jgp.0000235763.50230.83 · Cited by 168
Self-citation
Efficacy of treatment in older depressed patients: A systematic review and meta-analysis of double-blind randomized controlled trials with antidepressants
Kok, R. M., Nolen, W. A., & Heeren, T. J. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.02.036 · Cited by 167
A common challenge in older adults: Classification, overlap, and therapy of depression and dementia
Leyhe, T., Reynolds, C. F., Melcher, T., Linnemann, C., Klöppel, S., Blennow, K., Zetterberg, H., Dubois, B., Lista, S., & Hampel, H. J. (2016) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2016.08.007 · Cited by 175
Geriatric Depression in Primary Care
Park, M., & Unützer, J. (2011) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2011.02.009 · Cited by 150
A Systematic Review and Meta-analysis of Psychotherapy for Late-Life Depression
Huang, A. X., Delucchi, K., Dunn, L. B., & Nelson, J. C. (2014) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2014.04.003 · Cited by 147
Is psychotherapy for depression equally effective in younger and older adults? A meta-regression analysis
Cuijpers, P. J., van Straten, A., Smit, F., & Andersson, G. (2008) · International Psychogeriatrics · doi:10.1017/s1041610208008089 · Cited by 141
Design Makes a Difference: A Meta-Analysis of Antidepressant Response Rates in Placebo-Controlled Versus Comparator Trials in Late-Life Depression
Sneed, J. R., Rutherford, B. R., Rindskopf, D., Lane, D. T., Sackeim, H. A., & Roose, S. P. (2008) · The American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e3181256b1d · Cited by 140
Meta‐analysis of problem solving therapy for the treatment of major depressive disorder in older adults
Kirkham, J. G., Choi, N., & Seitz, D. P. (2016) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.4358 · Cited by 136
Meta-analysis comparing different behavioral treatments for late-life anxiety
Thorp, S. R., Ayers, C. R., Nuevo, R., Stoddard, J. A., Sorrell, J. T., & Wetherell, J. L. (2009) · The American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e31818b3f7e · Cited by 134
Depression Among Older Adults with Diabetes Mellitus
Park, M., & Reynolds, C. F. (2015) · Clinics in Geriatric Medicine · doi:10.1016/j.cger.2014.08.022 · Cited by 126
A randomised controlled trial of cognitive behaviour therapy vs treatment as usual in the treatment of mild to moderate late life depression
Laidlaw, K., Davidson, K. M., Toner, H., Jackson, G. A., Clark, S. A., Law, J., Howley, M., Bowie, G., Connery, H., & Cross, S. (2008) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.1993 · Cited by 122
Under-treatment of depression in older persons
Barry, L. C., Abou, J. J., Simen, A. A., & Gill, T. M. (2011) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.09.038 · Cited by 125
Is group psychotherapy effective in older adults with depression? A systematic review
Krishna, M., Jauhari, A., Lepping, P., Turner, J., Crossley, D., & Krishnamoorthy, A. (2011) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.2546 · Cited by 111
National recommendations: Psychosocial management of diabetes in India
Kalra, S., Sridhar, G. R., Balhara, Y. P. S., Sahay, R. K., Bantwal, G., Baruah, M., John, M., Unnikrishnan, A., Madhu, K., Verma, K., et al. (2013) · Indian Journal of Endocrinology and Metabolism · doi:10.4103/2230-8210.111608 · Cited by 106
Outcomes and Predictors of Late-Life Depression Trajectories in Older Primary Care Patients
Cui, X., Lyness, J. M., Tang, W., Tu, X. M., & Conwell, Y. (2008) · American Journal of Geriatric Psychiatry · doi:10.1097/01.jgp.0000308881.22956.27 · Cited by 107
Self-citation
Clinical practice guidelines for management of depression in elderly
Avasthi, A., & Grover, S. (2018) · Indian Journal of Psychiatry · doi:10.4103/0019-5545.224474 · Cited by 99
Post‐stroke depression: the case for augmented, individually tailored cognitive behavioural therapy
Broomfield, N. M., Laidlaw, K., Hickabottom, E., Murray, M. F., Pendrey, R., Whittick, J. E., & Gillespie, D. C. (2011) · Clinical Psychology & Psychotherapy · doi:10.1002/cpp.711 · Cited by 99
Adapting Interpersonal Psychotherapy for Older Adults at Risk for Suicide
Heisel, M. J., Talbot, N. L., King, D. A., Tu, X. M., & Duberstein, P. R. (2015) · The American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2014.03.010 · Cited by 96
Self-citation
One-year outcomes of minor and subsyndromal depression in older primary care patients
Lyness, J. M., Chapman, B. P., McGriff, J., Drayer, R., & Duberstein, P. R. (2009) · International Psychogeriatrics · doi:10.1017/s1041610208007746 · Cited by 96
Self-citation
Aging, mental health, and demographic change: Challenges for psychotherapists.
Laidlaw, K., & Pachana, N. A. (2009) · Professional Psychology Research and Practice · doi:10.1037/a0017215 · Cited by 105
Primary Care Physician Office Visits for Depression by Older Americans
Harman, J. S., Veazie, P. J., & Lyness, J. M. (2006) · Journal of General Internal Medicine · doi:10.1111/j.1525-1497.2006.00497.x · Cited by 106
Self-citation
Psychosocial Interventions for Late-life Major Depression: Evidence-Based Treatments, Predictors of Treatment Outcomes, and Moderators of Treatment Effects
Kiosses, D. N., Leon, A. C., & Areán, P. A. (2011) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2011.03.001 · Cited by 91
Antidepressants in elderly: Metaregression of double-blind, randomized clinical trials
Calati, R., Signorelli, M. S., Balestri, M., Marsano, A., Ronchi, D. D., Aguglia, E., & Serretti, A. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.11.053 · Cited by 95
The Impact of Depressive Symptoms and Chronic Diseases on Active Life Expectancy in Older Americans
Reynolds, S. L., Haley, W. E., & Kozlenko, N. (2008) · American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e31816ff32e · Cited by 90
Long-Term Results of a Web-Based Guided Self-Help Intervention for Employees With Depressive Symptoms: Randomized Controlled Trial
Geraedts, A. S., Kleiboer, A. M., Twisk, J., Wiezer, N. M., van Mechelen, W., & Cuijpers, P. (2014) · Journal of Medical Internet Research · doi:10.2196/jmir.3539 · Cited by 89
“Research on the treatment of depression has been extensive and has shown that depression can be treated effectively with different forms of psychotherapies [13-18].”
Geriatric Psychiatry Review: Differential Diagnosis and Treatment of the 3 D’s - Delirium, Dementia, and Depression
Downing, L. J., Caprio, T. V., & Lyness, J. M. (2013) · Current Psychiatry Reports · doi:10.1007/s11920-013-0365-4 · Cited by 97
Self-citation
Depressive symptoms are associated with allostatic load among community-dwelling older adults
Kobrosly, R. W., van Wijngaarden, E., Seplaki, C. L., Cory‐Slechta, D. A., & Moynihan, J. A. (2013) · Physiology & Behavior · doi:10.1016/j.physbeh.2013.10.014 · Cited by 94
Suicide Prevention in Older Adults.
Heisel, M. J., & Duberstein, P. R. (2005) · Clinical Psychology: Science and Practice · doi:10.1093/clipsy.bpi030 · Cited by 85
Self-citation
The prevention of depression in nursing home residents: A randomized clinical trial of cognitive–behavioral therapy
Konnert, C. A., Dobson, K. S., & Stelmach, L. (2009) · Aging & Mental Health · doi:10.1080/13607860802380672 · Cited by 82
Risks for Depression Onset in Primary Care Elderly Patients: Potential Targets for Preventive Interventions
Lyness, J. M., Yu, Q., Tang, W., Tu, X. M., & Conwell, Y. (2009) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2009.08101489 · Cited by 76
Self-citation
Modular psychotherapy for anxiety in older primary care patients
Wetherell, J. L., Ayers, C. R., Sorrell, J. T., Thorp, S. R., Nuevo, R., Belding, W., Gray, E., Stanley, M. A., Areán, P. A., Donohue, M., et al. (2009) · The American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e3181a31fb5 · Cited by 78
A Minimal Psychological Intervention in Chronically Ill Elderly Patients with Depression: A Randomized Trial
Lamers, F., Jonkers, C. C. M., Bosma, H., Kempen, G. I. J. M., Meijer, J. A. M. J., Penninx, B. W. J. H., Knottnerus, J. A., & van Eijk, J. T. M. (2010) · Psychotherapy and Psychosomatics · doi:10.1159/000313690 · Cited by 74
Adapting interpersonal psychotherapy for older adults at risk for suicide: Preliminary findings
Heisel, M. J., Duberstein, P. R., Talbot, N. L., King, D. A., & Tu, X. M. (2009) · Professional Psychology: Research and Practice · doi:10.1037/a0014731 · Cited by 72
Self-citation
‘A no means no’—measuring depression using a single-item question versus Hospital Anxiety and Depression Scale (HADS-D)
Skoogh, J., Ylitalo, N., Omérov, P., Hauksdóttir, A., Nyberg, U., Wilderäng, U., Johansson, B. E. A., Gatz, M., & Steineck, G. (2010) · Annals of Oncology · doi:10.1093/annonc/mdq058 · Cited by 71
The Effect of Cognitive Behavioral Group Therapy for Depression: A Meta‐Analysis 2000–2010
Feng, C., Chu, H., Chen, C., Chang, Y., Chen, T., Chou, Y., Chang, Y., & Chou, K. (2012) · Worldviews on Evidence-Based Nursing · doi:10.1111/j.1741-6787.2011.00229.x · Cited by 66
Age differences in treatment response to a collaborative care intervention for anxiety disorders
Wetherell, J. L., Petkus, A. J., Thorp, S. R., Stein, M. B., Chavira, D. A., Campbell-Sills, L., Craske, M. G., Sherbourne, C., Bystritsky, A., Sullivan, G., et al. (2013) · British Journal of Psychiatry · doi:10.1192/bjp.bp.112.118547 · Cited by 65
Effects of Testosterone Replacement in Middle-Aged Men With Dysthymia
Seidman, S. N., Orr, G., Raviv, G., Levi, R., Roose, S. P., Kravitz, E., Amiaz, R., & Weiser, M. (2009) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0b013e3181a39137 · Cited by 63
Pain severity predicts depressive symptoms over and above individual illnesses and multimorbidity in older adults
Sharpe, L., McDonald, S., Correia, H., Raue, P. J., Meade, T., Nicholas, M. K., & Areán, P. A. (2017) · BMC Psychiatry · doi:10.1186/s12888-017-1334-y · Cited by 63
Outcomes of Subsyndromal Depression in Older Primary Care Patients
Grabovich, A., Lu, N., Tang, W., Tu, X. M., & Lyness, J. M. (2010) · American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e3181cb87d6 · Cited by 59
Self-citation
Childhood Sexual Abuse is Associated With Physical Illness Burden and Functioning in Psychiatric Patients 50 Years of Age and Older
Talbot, N. L., Chapman, B. P., Conwell, Y., McCollumn, K. R., Franus, N., Cotescu, S., & Duberstein, P. R. (2009) · Psychosomatic Medicine · doi:10.1097/psy.0b013e318199d31b · Cited by 56
Self-citation
Older Adults With Severe, Treatment-Resistant Depression
Unützer, J., & Park, M. (2012) · JAMA · doi:10.1001/2012.jama.10690 · Cited by 56
Short-Term Effects of a Web-Based Guided Self-Help Intervention for Employees With Depressive Symptoms: Randomized Controlled Trial
Geraedts, A. S., Kleiboer, A. M., Wiezer, N. M., van Mechelen, W., & Cuijpers, P. (2014) · Journal of Medical Internet Research · doi:10.2196/jmir.3185 · Cited by 48
Late-life Depression: Evidence-based Treatment and Promising New Directions for Research and Clinical Practice
Andreescu, C., & Reynolds, C. F. (2011) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2011.02.005 · Cited by 54
Subthreshold Depression Needs A Prime Time In Old Age Psychiatry? A Narrative Review Of Current Evidence
Biella, M. M., Borges, M. K., Strauss, J., Mauer, S., Martinelli, J. E., & Aprahamian, I. (2019) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s223640 · Cited by 55
Effect of vitamin D deficiency on depressive symptoms in child and adolescent psychiatric patients: results of a randomized controlled trial
Libuda, L., Timmesfeld, N., Antel, J., Hirtz, R., Bauer, J. J., Führer, D., Zwanziger, D., Öztürk, D., Langenbach, G., Hahn, D., et al. (2020) · European Journal of Nutrition · doi:10.1007/s00394-020-02176-6 · Cited by 55
The impact of executive function on response to cognitive behavioral therapy in late-life depression: Executive function and CBT response in late-life depression
Goodkind, M. S., Gallagher-Thompson, D., Thompson, L. W., Kesler, S. R., Anker, L., Flournoy, J., Berman, M. P., Holland, J. M., & O'Hara, R. M. (2016) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.4325 · Cited by 50
Personality and risk for depression in a birth cohort of 70-year-olds followed for 15 years
Duberstein, P. R., Palsson, S. P., Wærn, M., & Skoog, I. G. (2008) · Psychological Medicine · doi:10.1017/s0033291707002620 · Cited by 50
Self-citation
Developing quality indicators for general practice care for vulnerable elders; transfer from US to The Netherlands
van der Ploeg, E., Depla, M. F. I. A., Shekelle, P., et al. (2008) · BMJ Quality & Safety · doi:10.1136/qshc.2007.023226 · Cited by 49
The effects of psychotherapy on reducing depression in residential aged care: a meta-analytic review
Cody, R. A., & Drysdale, K. (2013) · Clinical Gerontologist · doi:10.1080/07317115.2012.731474 · Cited by 43
Measuring symptoms and diagnosing mental disorders in the elderly community: the test–retest reliability of the CIDI65+
Wïttchen, H., Strehle, J., Gerschler, A., Volkert, J., Dehoust, M. C., Sehner, S., Wegscheider, K., Ausín, B., Canuto, A., Crawford, M., et al. (2014) · International Journal of Methods in Psychiatric Research · doi:10.1002/mpr.1455 · Cited by 46
Naturalistic outcomes of minor and subsyndromal depression in older primary care patients
Lyness, J. M. (2008) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.1982 · Cited by 45
Self-citation
Use of Antidepressants in Late-Life Depression
Rajji, T. K., Mulsant, B. H., Lotrich, F. E., Lokker, C., & Reynolds, C. F. (2008) · Drugs & Aging · doi:10.2165/00002512-200825100-00003 · Cited by 48
Is Depression Viewed as an Inevitable Consequence of Age? The “Understandability Phenomenon” in Older People
Law, J., Laidlaw, K., & Peck, D. (2010) · Clinical Gerontologist · doi:10.1080/07317111003773627 · Cited by 42
Contradictory effects for prevention of depression and anxiety in residents in homes for the elderly: a pragmatic randomized controlled trial
Dozeman, E., van Marwijk, H., van Schaik, A., Smit, F., Stek, M. L., van der Horst, H. E., Bohlmeijer, E. T., & Beekman, A. T. F. (2012) · International Psychogeriatrics · doi:10.1017/s1041610212000178 · Cited by 44
Cognitive Behaviour Therapy: How is it Different with Older People?
Laidlaw, K., & McAlpine, S. (2008) · Journal of Rational-Emotive & Cognitive-Behavior Therapy · doi:10.1007/s10942-008-0085-6 · Cited by 44
Nutritional Modulation of the Gut–Brain Axis: A Comprehensive Review of Dietary Interventions in Depression and Anxiety Management
Merino, M., Clemente‐Suárez, V. J., Ruisoto, P., Jiménez, M., Ramos‐Campo, D. J., Beltrán-Velasco, A. I., Martínez‐Guardado, I., Rubio-Zarapuz, A., Navarro-Jiménez, E., & Tornero-Aguilera, J. F. (2024) · Metabolites · doi:10.3390/metabo14100549 · Cited by 60
Group arts interventions for depression and anxiety among older adults: a systematic review and meta-analysis
Quinn, E. A., Millard, E., & Jones, J. M. (2025) · Nature Mental Health · doi:10.1038/s44220-024-00368-1 · Cited by 52
Group, individual, and staff therapy: an efficient and effective cognitive behavioral therapy in long-term care
Hyer, L., Yeager, C. A., Hilton, N., & Sacks, A. (2009) · American Journal of Alzheimer's Disease & Other Dementias® · doi:10.1177/1533317508323571 · Cited by 41
AIDE–Acute Illness and Depression in Elderly Patients. Cognitive Behavioral Group Psychotherapy in Geriatric Patients With Comorbid Depression: A Randomized, Controlled Trial
Hummel, J., Weisbrod, C., Boesch, L., Himpler, K., Hauer, K. A., Hautzinger, M., Gäbel, A., Zieschang, T., Fickelscherer, A., Diener, S. J., et al. (2016) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2016.10.009 · Cited by 44
Publication bias in meta-analyses of the efficacy of psychotherapeutic interventions for depression.
Niemeyer, H., Musch, J., & Pietrowsky, R. (2012) · Journal of Consulting and Clinical Psychology · doi:10.1037/a0031152 · Cited by 35
Depression in the Elderly. Consensus Statement of the Spanish Psychogeriatric Association
Agüera-Ortíz, L., Claver-Martín, M. D., Franco-Fernández, M. D., López‐Álvarez, J., Martı́n-Carrasco, M., Ramos-García, M. I., & Sánchez-Pérez, M. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00380 · Cited by 38
Comparative effectiveness of antidepressants on geriatric depression: Real-world evidence from a population-based study
Hsu, C., Tseng, W., Wang, L., Yang, Y., Kao, H.-Y., & Lin, P. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2021.10.009 · Cited by 37
Low-grade inflammation and endothelial dysfunction predict four-year risk and course of depressive symptoms: The Maastricht study
Janssen, E. P. C. J., Köhler, S., Geraets, A. F. J., Stehouwer, C. D. A., Schaper, N. C., Sep, S. J. S., Henry, R. M. A., Kallen, C., Schalkwijk, C. G., Koster, A., et al. (2021) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2021.06.013 · Cited by 33
Mental Health Service Use Among Lesbian, Gay, and Bisexual Older Adults
Stanley, I. H., & Duong, J. (2015) · Psychiatric Services · doi:10.1176/appi.ps.201400488 · Cited by 31
Commentary on evidence-based psychological treatments for older adults.
Gatz, M. (2007) · Psychology and Aging · doi:10.1037/0882-7974.22.1.52 · Cited by 31
Psychological Treatment of Late-Life Depression
Francis, J., & Kumar, A. (2013) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2013.08.005 · Cited by 30
Pharmacogenetics and the serotonin transporter in late-life depression
Gerretsen, P., & Pollock, B. G. (2008) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1517/17425250802560279 · Cited by 30
Executive dysfunction in late-life depression.
Rajtar-Zembaty, A., Sałakowski, A., Rajtar-Zembaty, J., & Starowicz–Filip, A. (2016) · Psychiatria Polska · doi:10.12740/pp/onlinefirst/63765 · Cited by 39
Depression in older age: A scoping study
Haralambous, B., Tinney, J., & Bryant, C. (2009) · Cited by 28
Should antidepressants be used in minor depression?
Naber, D., & Bullinger, M. (2018) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2018.20.3/dnaber · Cited by 26
The Psychosocial Challenges and Care of Older Adults with Diabetes: “Can’t Do What I Used To Do; Can’t Be Who I Once Was”
Beverly, E. A., Ritholz, M. D., Shepherd, C., & Weinger, K. (2016) · Current Diabetes Reports · doi:10.1007/s11892-016-0741-7 · Cited by 31
Older Adults' Acceptance of Psychological, Pharmacological, and Combination Treatments for Geriatric Depression
Hanson, A., & Scogin, F. R. (2008) · The Journals of Gerontology Series B · doi:10.1093/geronb/63.4.p245 · Cited by 26
Correlates of knowledge and beliefs about depression among long‐term care staff
Ayalon, L., Areán, P. A., & Bornfeld, H. (2007) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.1884 · Cited by 25

Authors: Pinquart, M., Duberstein, P. R., & Lyness, J. M.
Affiliations: Friedrich Schiller University Jena (DE)
ORCID: Pinquart, Martin
Duberstein, Paul R.
Venue: American Journal of Psychiatry
Publisher: American Psychiatric Association Publishing
Published: 2006-09
Volume: 163
Issue: 9
Pages: 1493-1501
ISSN: 0002-953X (ISSN-L)
1535-7228
DOI: 10.1176/ajp.2006.163.9.1493
OpenAlex: W2128077214
Cited by: 204
References: 51
Citations by year: 2026: 1 · 2025: 6 · 2024: 6 · 2023: 8 · 2022: 8 · 2021: 5 · 2020: 12 · 2019: 7 · 2018: 7 · 2017: 5 · 2016: 14 · 2015: 19 · 2014: 8 · 2013: 16 · 2012: 12
FWCI: 16.61
Type: journal article
Language: en
Open access: closed
Locations: American Journal of Psychiatry (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5r01mh061429-05)
National Institute of Mental Health (R01 MH-61429, R01 MH-64579, R01MH064579)
Topics: Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
Keywords: geriatric depression, older adults, pharmacotherapy, psychotherapy, major depressive disorder, minor depression, dysthymia, treatment comparison, active placebo, effect size, self-rated depression
MeSH terms: Aged, Antidepressive Agents, Depressive Disorder, Major, Major Depressive Disorder, Depressive Disorder, Humans, Psychotherapy, Randomized Controlled Trials as Topic, Treatment Outcome, Dysthymic Disorder

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Treatments for Later-Life Depressive Conditions: A Meta-Analytic Comparison of Pharmacotherapy and Psychotherapy

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks