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Psychiatric Aspects of Impulsivity
Abstract
OBJECTIVE: The authors discuss the relationship of impulsivity to psychiatric disorders and present selected hypotheses regarding the reasons for these relationships. METHOD: Previous research has shown significantly higher levels of impulsivity among patients with conduct disorder, personality disorders, substance use disorders, and bipolar disorder, compared to other psychiatric patients or healthy comparison subjects. A literature review of the theoretical bases of the relationship between these disorders and impulsivity is presented. Measurements of impulsivity and treatment options are discussed in relation to the physiology of impulsivity and the disorders in which it is a prominent feature. RESULTS: Impulsivity, as defined on the basis of a biopsychosocial approach, is a key feature of several psychiatric disorders. Behavioral and pharmacological interventions that are effective for treating impulsivity should be incorporated into treatment plans for these disorders. CONCLUSIONS: The high comorbidity of impulsivity and selected psychiatric disorders, including personality disorders, substance use disorders, and bipolar disorder, is in a large part related to the association between impulsivity and the biological substrates of these disorders. Before treatment studies on impulsivity can move forward, measures of impulsivity that capture the core aspects of this behavior need to be refined and tested on the basis of an ideologically neutral model of impulsivity.
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“Impulsive behavior is a key characteristic of several psychiatric conditions, including attention deficit/hyperactivity disorder (ADHD) (Moeller et al, 2001).”
From DAT1 and COMT effects on delay discounting and trait impulsivity in male adolescents with attention deficit/hyperactivity disorder and healthy controls (2010) · cites this paper as Moeller et al, 2001
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Self-citation
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Koob, G. F., & Volkow, N. D. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.110 · Cited by 5,340
Neurobiology of addiction: a neurocircuitry analysis
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Inhibition and impulsivity: behavioral and neural basis of response control
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Chambers, R. A., Taylor, J. R., & Potenza, M. N. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.6.1041 · Cited by 1,719
Impulsivity, compulsivity, and top-down cognitive control
Dalley, J. W., Everitt, B. J., & Robbins, T. W. (2011) · Neuron · doi:10.1016/j.neuron.2011.01.020 · Cited by 1,589
Metadata
- Authors
- Moeller, F. G., Barratt, E. S., Dougherty, D. M., Schmitz, J. M., & Swann, A. C.
- Affiliations
- The University of Texas Health Science Center at Houston (US)
- Venue
- American Journal of Psychiatry
- Published
- 2001-11-01
- Volume
- 158
- Issue
- 11
- Pages
- 1783-1793
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2166344210
- Cited by
- 2,747
- References
- 118
- Citations by year
- 2026: 100 · 2025: 141 · 2024: 142 · 2023: 159 · 2022: 148 · 2021: 163 · 2020: 200 · 2019: 148 · 2018: 145 · 2017: 138 · 2016: 127 · 2015: 137 · 2014: 122 · 2013: 139 · 2012: 140
- FWCI
- 5.33
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01da008425-08)
- National Institute on Drug Abuse (DA-00403, DA08425)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- impulsivity, mental illness, conduct disorder, personality disorders, substance use disorders, bipolar disorder, impulsivity measurement, behavioral interventions, biopsychosocial model
- MeSH terms
- Antisocial Personality Disorder, Bipolar Disorder, Borderline Personality Disorder, Evoked Potentials, Humans, Disruptive, Impulse Control, and Conduct Disorders, Personality Inventory, Psychotherapy, Antipsychotic Agents, Comorbidity, Substance-Related Disorders
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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