The DOI matches its Crossref record; 39 of the 40 references it cites were found in a registry or an index.
d-Cycloserine as an Augmentation Strategy With Cognitive-Behavioral Therapy for Social Anxiety Disorder
Open accessAbstract
OBJECTIVE: The authors examined whether D-cycloserine, a partial agonist at the glutamatergic N-methyl-d-aspartate receptor, augments and accelerates a full course of comprehensive cognitive-behavioral therapy (CBT) in adults with generalized social anxiety disorder. METHOD: This was a multisite randomized placebo-controlled efficacy study with 169 medication-free adults with generalized social anxiety disorder, of whom 144 completed the 12-week treatment and 131 completed the three follow-up assessments. Patients were randomly assigned to receive 50 mg of D-cycloserine or placebo 1 hour before each of five exposure sessions that were part of a 12-session cognitive-behavioral group treatment. Response and remission status was determined at baseline, throughout treatment, at end of treatment, and at 1-, 3-, and 6-month follow-up assessments by assessors who were blind to treatment condition. RESULTS: D-Cycloserine-augmented and placebo-augmented CBT were associated with similar completion rates (87% and 82%), response rates (79.3% and 73.3%), and remission rates (34.5% and 24.4%) at the posttreatment assessment; response and remission rates were largely maintained at the follow-up assessments. Although D-cycloserine was associated with a 24%-33% faster rate of improvement in symptom severity and remission rates relative to placebo during the treatment phase, the groups did not differ in response and remission rates. CONCLUSIONS: D-Cycloserine did not augment a full course of comprehensive CBT for social anxiety disorder.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“This study aligns with previous research about the efficacy of CBT on SAD symptoms.”
From Trial-Based Cognitive Therapy: Efficacy of a New CBT Approach for Treating Social Anxiety Disorder with Comorbid Depression. (2018) · cites this paper as Hofmann et al. 2013
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“although null effects have also been reported (Hofmann et al., 2013).”
From Virtual Reality exposure therapy in the treatment of public speaking anxiety and social anxiety disorder (2024) · cites this paper as Hofmann et al., 2013
The check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“Fluvoxamine was found to be well tolerated and short-time effective for anxiety disorders.”
From The risks versus the benefits of pharmacological intervention in social anxiety disorder in children (2025) · cites this paper as [39]
Experimental — accuracy not yet measuredThe check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“Despite the described benefits, the authors raise awareness of its potential risks such as cognitive impairment, disinhibition, depression and dependence.”
From The risks versus the benefits of pharmacological intervention in social anxiety disorder in children (2025) · cites this paper as [39]
Experimental — accuracy not yet measuredIn the citing paper
“Shortly thereafter, several groups reported that DCS administration before or after exposure therapy, a form of treatment based on the principles of fear extinction learning, was effective in alleviating the symptoms of acrophobia (67), panic disorder (68), social anxiety disorder (69, 70), and obsessive–compulsive disorder (71–73).”
From Conditioned fear associated phenotypes as robust, translational indices of trauma-, stressor-, and anxiety-related behaviors (2014) · cites this paper as [70]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Kessler, R. C., Berglund, P., Demler, O., Jin, R., Merikangas, K. R., & Walters, E. E. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.6.593 · Cited by 20,391
A new depression scale designed to be sensitive to change
Montgomery, S. A., & Åsberg, M. (1979) · British Journal of Psychiatry · doi:10.1192/bjp.134.4.382 · Cited by 13,962
Applied Longitudinal Data Analysis: Modeling Change and Event Occurrence
Singer, J. D., & Willett, J. B. (2003) · doi:10.1093/acprof:oso/9780195152968.001.0001 · Cited by 10,647
Liebowitz, M. R. (2015) · Modern Trends in Pharmacopsychiatry · doi:10.1159/000414022 · Cited by 2,266
Hofmann, S. G. (2007) · Cognitive Behaviour Therapy · doi:10.1080/16506070701421313 · Cited by 1,064 · cited 1×
“Session 8-12 involved a combination of cognitive restructuring and individually tailored in vivo exposure practices designed to challenge tbe patient's maladaptive beliefs about the negative consequences of social mishaps (36).”
BackgroundSelf-citationRessler, K. J., Rothbaum, B. O., Tannenbaum, L., Anderson, P., Graap, K., Zimand, E., Hodges, L., & Davis, M. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.11.1136 · Cited by 1,063
Behavioral and Neural Analysis of Extinction
Myers, K. M., & Davis, M. (2002) · Neuron · doi:10.1016/s0896-6273(02)01064-4 · Cited by 918
Walker, D. L., Ressler, K. J., Lu, K.-T., & Davis, M. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-06-02343.2002 · Cited by 815
Extinction of fear-potentiated startle: blockade by infusion of an NMDA antagonist into the amygdala
Falls, W., Miserendino, M., & Davis, M. (1992) · The Journal of Neuroscience · doi:10.1523/jneurosci.12-03-00854.1992 · Cited by 673
Cognitive Behavioral Group Therapy vs Phenelzine Therapy for Social Phobia: 12-Week Outcome
Heimberg, R. G., Liebowitz, M. R., Hope, D. A., Schneier, F. R., Holt, C. S., Welkowitz, L. A., Juster, H. R., Campeas, R., Bruch, M. A., Cloitre, M., et al. (1998) · Archives of General Psychiatry · doi:10.1001/archpsyc.55.12.1133 · Cited by 585
Research works printed but not linked: 3
- Otto MW, 2005, Clin Psychol, 12, 72
- First MB, 1995, Structured Clinical Interview for DSM-IV Axis I Disorders, Patient Edition
- DiNardo PA, 1994, Anxiety Disorders Interview Schedule for DSM-IV: Lifetime Version (ADIS-IV-L)
Cited by
Sorted by citations
From Pavlov to PTSD: The extinction of conditioned fear in rodents, humans, and anxiety disorders
VanElzakker, M. B., Kathryn Dahlgren, M., Caroline Davis, F., Dubois, S., & Shin, L. M. (2014) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2013.11.014 · Cited by 482
Pharmacotherapy of Anxiety Disorders: Current and Emerging Treatment Options
Garakani, A., Murrough, J. W., Freire, R. C., Thom, R. P., Larkin, K., Buono, F. D., & Iosifescu, D. V. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.595584 · Cited by 440
Singewald, N., Schmuckermair, C., Whittle, N., Holmes, A., & Ressler, K. J. (2015) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2014.12.004 · Cited by 390
Rothbaum, B. O., Price, M., Jovanovic, T., Norrholm, S. D., Gerardi, M., Dunlop, B., Davis, M., Bradley, B., Duncan, E. J., Rizzo, A., et al. (2014) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2014.13121625 · Cited by 388
Leigh, H. (2014) · Springer eBooks · doi:10.1007/978-3-319-11005-9_14 · Cited by 309
Mataix-Cols, D., Fernández de la Cruz, L., Monzani, B., Rosenfield, D., Andersson, E., Pérez-Vigil, A., Frumento, P., de Kleine, R. A., Difede, J., Dunlop, B. W., et al. (2017) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2016.3955 · Cited by 288
Self-citationAndrews, G., Bell, C., Boyce, P., Gale, C., Lampe, L., Marwat, O., Rapee, R., & Wilkins, G. (2018) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867418799453 · Cited by 243
Brain connectomics predict response to treatment in social anxiety disorder
Whitfield-Gabrieli, S., Ghosh, S. S., Nieto-Castanon, A., Saygin, Z., Doehrmann, O., Chai, X. J., Reynolds, G. O., Hofmann, S. G., Pollack, M. H., & Gabrieli, J. D. E. (2016) · Molecular Psychiatry · doi:10.1038/mp.2015.109 · Cited by 210
Self-citationExercise augmentation of exposure therapy for PTSD: rationale and pilot efficacy data
Powers, M. B., Medina, J. L., Burns, S., Kauffman, B. Y., Monfils, M., Asmundson, G. J. G., Diamond, A., McIntyre, C., & Smits, J. A. J. (2015) · Cognitive Behaviour Therapy · doi:10.1080/16506073.2015.1012740 · Cited by 194
Milad, M. R., Rosenbaum, B. L., & Simon, N. M. (2014) · Behaviour Research and Therapy · doi:10.1016/j.brat.2014.08.006 · Cited by 175
Self-citationTreatment-refractory anxiety; definition, risk factors, and treatment challenges
Roy‐Byrne, P. (2015) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2015.17.2/proybyrne · Cited by 162
D-Cycloserine in Neuropsychiatric Diseases: A Systematic Review
Schade, S., & Paulus, W. (2016) · International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyv102 · Cited by 135
Scheveneels, S., Boddez, Y., Vervliet, B., & Hermans, D. (2016) · Behaviour Research and Therapy · doi:10.1016/j.brat.2016.08.015 · Cited by 152
Clinical Features, Cognitive Biases, and Treatment of Body Dysmorphic Disorder
Fang, A., & Wilhelm, S. (2015) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-032814-112849 · Cited by 127
Self-citationHDAC inhibitors as cognitive enhancers in fear, anxiety and trauma therapy: Where do we stand?
Whittle, N., & Singewald, N. (2014) · Biochemical Society Transactions · doi:10.1042/bst20130233 · Cited by 117
Brain sites involved in fear memory reconsolidation and extinction of rodents
Baldi, E., & Bucherelli, C. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.04.003 · Cited by 123
Smits, J. A. J., Rosenfield, D., Otto, M. W., Marques, L., Davis, M. L., Meuret, A. E., Simon, N. M., Pollack, M. H., & Hofmann, S. G. (2013) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2013.06.020 · Cited by 114
“This is similar to previous studies from our group (e.g., Hofmann, 2004; Hofmann et al.2006), which have shown”
BackgroundInfluentialSelf-citationCorrell, C. U., Solmi, M., Cortese, S., D, M. F. M., Højlund, M., KRAEMER, H. C., McIntyre, R. S., Pine, D. S., Schneider, L. S. S., & Kane, J. M. (2023) · World Psychiatry · doi:10.1002/wps.21056 · Cited by 115
Andersson, E., Hedman‐Lagerlöf, E., Enander, J., Djurfeldt, D. R., Ljótsson, B., Červenka, S., Isung, J., Svanborg, C., Mataix‐Cols, D., Kaldo, V., et al. (2015) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2015.0546 · Cited by 113
Hofmann, S. G. (2014) · Depression and Anxiety · doi:10.1002/da.22257 · Cited by 108
Self-citationEl Alaoui, S., Hedman, E., Kaldo, V., Hesser, H., Kraepelien, M., Andersson, E., Rück, C., Andersson, G., Ljótsson, B., & Lindefors, N. (2015) · Journal of Consulting and Clinical Psychology · doi:10.1037/a0039198 · Cited by 99
Storch, E. A., Wilhelm, S., Sprich, S. E., Henin, A., Micco, J. A., Small, B. J., Mcguire, J. F., Mutch, P. J., Lewin, A. B., Murphy, T. K., et al. (2016) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2016.1128 · Cited by 111
Briscione, M. A., Jovanovic, T., & Norrholm, S. D. (2014) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2014.00088 · Cited by 105
Norrholm, S. D., Jovanović, T., Gerardi, M. A., Breazeale, K. G., Price, M., Davis, M., Duncan, E., Ressler, K. J., Bradley, B., Rizzo, A., et al. (2016) · Behaviour Research and Therapy · doi:10.1016/j.brat.2016.05.002 · Cited by 96
Ori, R., Amos, T., Bergman, H., Soares‐Weiser, K., Ipser, J., & Stein, D. J. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007803.pub2 · Cited by 104
Yohimbine Enhancement of Exposure Therapy for Social Anxiety Disorder: A Randomized Controlled Trial
Smits, J. A. J., Rosenfield, D., Davis, M. L., Julian, K., Handelsman, P. R., Otto, M. W., Tuerk, P., Shiekh, M., Rosenfield, B., Hofmann, S. G., et al. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.10.008 · Cited by 86
Self-citationFear Processing, Psychophysiology, and PTSD
Norrholm, S. D., & Jovanović, T. (2018) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000189 · Cited by 92
Fear as a translational mechanism in the psychopathology of anorexia nervosa
Murray, S. B., Strober, M., Craske, M. G., Griffiths, S., Levinson, C. A., & Strigo, I. A. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.10.013 · Cited by 75
Zalta, A. K., Dowd, S., Rosenfield, D., Smits, J. A. J., Otto, M. W., Simon, N. M., Meuret, A. E., Marques, L., Hofmann, S. G., & Pollack, M. H. (2013) · Depression and Anxiety · doi:10.1002/da.22170 · Cited by 68
Self-citationd-Cycloserine Augmentation of Cognitive Behavioral Therapy for Anxiety Disorders: an Update
Hofmann, S. G., Otto, M. W., Pollack, M. H., & Smits, J. A. J. (2014) · Current Psychiatry Reports · doi:10.1007/s11920-014-0532-2 · Cited by 76
Self-citationReinecke, A., Thilo, K., Filippini, N., Croft, A., & Harmer, C. J. (2014) · Behaviour Research and Therapy · doi:10.1016/j.brat.2014.07.017 · Cited by 75
Core Mechanisms of Cognitive Behavioral Therapy for Anxiety and Depression
Powers, M. B., de Kleine, R. A., & Smits, J. A. J. (2017) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2017.08.010 · Cited by 83
Self-citationTelch, M. J., Bruchey, A. K., Rosenfield, D., Cobb, A. R., Smits, J. A. J., Pahl, S. A., & Gonzalez-Lima, F. (2014) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2014.13101407 · Cited by 77
Self-citationEnhancement of psychosocial treatment with D-cycloserine: Models, moderators, and future directions
Otto, M. W., Kredlow, M. A., Smits, J. A. J., Hofmann, S. G., Tolin, D. F., de Kleine, R. A., van Minnen, A., Evins, A. E., & Pollack, M. H. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.09.007 · Cited by 70
Self-citationRANDOMIZED TRIAL OF D-CYCLOSERINE ENHANCEMENT OF COGNITIVE-BEHAVIORAL THERAPY FOR PANIC DISORDER
Otto, M. W., Pollack, M. H., Dowd, S. M., Hofmann, S. G., Pearlson, G. D., Szuhany, K. L., Gueorguieva, R. V., Krystal, J. H., Simon, N. M., & Tolin, D. F. (2016) · Depression and Anxiety · doi:10.1002/da.22531 · Cited by 69
Self-citationThe glycine site of NMDA receptors: A target for cognitive enhancement in psychiatric disorders
Peyrovian, B., Rosenblat, J. D., Pan, Z., Iacobucci, M., Brietzke, E. M., & McIntyre, R. S. (2019) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2019.02.001 · Cited by 76
Caballo, V. E., Martínez, B. A., Salazar, I. C., Muñiz, M. J. I., & Hofmann, S. G. (2015) · Psychological Assessment · doi:10.1037/a0038828 · Cited by 64
Self-citationd-Cycloserine as an augmentation strategy for cognitive behavioral therapy of anxiety disorders
Hofmann, S. G., Wu, J. Q., & Boettcher, H. (2013) · Biology of Mood & Anxiety Disorders · doi:10.1186/2045-5380-3-11 · Cited by 59
Self-citationMcGuire, J. F., Lewin, A. B., & Storch, E. A. (2014) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.2014.934677 · Cited by 57
“multicenter RCT that administered 12 sessions of group exposure-based CBT to 169 participants [41].”
MethodLevinson, C. A., Rodebaugh, T. L., Fewell, L., Kass, A. E., Riley, E. N., Stark, L., McCallum, K., & Lenze, E. J. (2015) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.14m09299 · Cited by 56
The future of psychological treatments: The Marburg Declaration
Rief, W., Asmundson, G. J. G., Bryant, R. A., Clark, D. M., Ehlers, A., Holmes, E. A., McNally, R. J., Neufeld, C. B., Wilhelm, S., Jaroszewski, A. C., et al. (2024) · Clinical Psychology Review · doi:10.1016/j.cpr.2024.102417 · Cited by 54
Self-citationA Meta-Analysis of d-Cycloserine in Exposure-Based Treatment
Mcguire, J. F., Wu, M. S., Piacentini, J. C., McCracken, J. T., & Storch, E. A. (2016) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.15r10334 · Cited by 52
D-cycloserine to enhance extinction of cue-elicited craving for alcohol: a translational approach
MacKillop, J., Few, L. R., Stojek, M. M., Murphy, C. M., Malutinok, S. F., Johnson, F. T., Hofmann, S. G., McGeary, J. E., Swift, R. M., & Monti, P. M. (2015) · Translational Psychiatry · doi:10.1038/tp.2015.41 · Cited by 46
Self-citationSmits, J. A. J., Hofmann, S. G., Rosenfield, D., Hopkins, L. B., Costa, P. T., Simon, N. M., O’Cleirigh, C. M., Meuret, A. E., Marques, L. M., Otto, M. W., et al. (2013) · Journal of Consulting and Clinical Psychology · doi:10.1037/a0034120 · Cited by 46
Self-citationBürkner, P.-C., Bittner, N., Holling, H., & Buhlmann, U. (2017) · PLoS ONE · doi:10.1371/journal.pone.0173660 · Cited by 41
d-Cycloserine ameliorates social alterations that result from prenatal exposure to valproic acid
Wellmann, K. A., Varlinskaya, E. I., & Mooney, S. M. (2014) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2014.08.001 · Cited by 40
The Role of the Medial Prefrontal Cortex in Regulating Social Familiarity-Induced Anxiolysis
Lungwitz, E. A., Stuber, G. D., Johnson, P. L., Dietrich, A. D., Schartz, N. D., Hanrahan, B., Shekhar, A., & Truitt, W. A. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2013.302 · Cited by 39
Bischoff, S., Wieder, G., Einsle, F., Petzold, M. B., Janßen, C., Mumm, J. L. M., Wittchen, H.-U., Fydrich, T., Plag, J., & Ströhle, A. (2018) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2018.03.001 · Cited by 36
D-CYCLOSERINE ENHANCES GENERALIZATION OF FEAR EXTINCTION IN CHILDREN
Byrne, S., Rapee, R. M., Richardson, R., Malhi, G. S., Jones, M., & Hudson, J. L. (2015) · Depression and Anxiety · doi:10.1002/da.22356 · Cited by 33
Dose Timing of D -Cycloserine to Augment Exposure Therapy for Social Anxiety Disorder
Smits, J. A. J., Pollack, M. H., Rosenfield, D., Otto, M. W., Dowd, S. M., Carpenter, J. K., Dutcher, C. D., Lewis, E. M., Witcraft, S. M., Papini, S., et al. (2020) · JAMA Network Open · doi:10.1001/jamanetworkopen.2020.6777 · Cited by 32
Self-citationPatin, A., & Hurlemann, R. (2015) · Handbook of experimental pharmacology · doi:10.1007/978-3-319-16522-6_10 · Cited by 37
Meuret, A. E., Chmielewski, M. S., Steele, A. M., Rosenfield, D., Petersen, S., Smits, J. A. J., Simon, N. M., Otto, M. W., Marques, L. M., Pollack, M. H., et al. (2016) · Behaviour Research and Therapy · doi:10.1016/j.brat.2016.03.008 · Cited by 36
Self-citationCalamaras, M. R., Tully, E. C., Tone, E. B., Price, M., & Anderson, P. L. (2015) · Behaviour Research and Therapy · doi:10.1016/j.brat.2015.06.006 · Cited by 32
Seuling, P. D., Czernin, N. S., & Schiele, M. A. (2024) · Neuroscience Applied · doi:10.1016/j.nsa.2024.104074 · Cited by 28
“For SAD, early studies on D-cycloserine administration during exposure in vivo have yielded promising results (Guastella et al., 2008; Hofmann et al., 2006; Rodrigues et al., 2014), although null effects have also been reported (Hofmann et al., 2013).”
Psychological treatment of social anxiety disorder improves body dysmorphic concerns
Fang, A., Sawyer, A. T., Aderka, I. M., & Hofmann, S. G. (2013) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2013.07.005 · Cited by 31
Self-citationNeuroenhancement of Exposure Therapy in Anxiety Disorders
Hofmann, S. G., Mundy, E. A., & Curtiss, J. E. (2015) · AIMS neuroscience · doi:10.3934/neuroscience.2015.3.123 · Cited by 27
Self-citationHofmann, S. G., Carpenter, J. K., Otto, M. W., Rosenfield, D., Smits, J. A. J., & Pollack, M. H. (2015) · Contemporary Clinical Trials · doi:10.1016/j.cct.2015.06.015 · Cited by 27
Self-citationTolin, D. F. (2017) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2017.08.007 · Cited by 25
Effect of d-cycloserine on fear extinction training in adults with social anxiety disorder
Hofmann, S. G., Papini, S., Carpenter, J. K., Otto, M. W., Rosenfield, D., Dutcher, C. D., Dowd, S. M., Lewis, M., Witcraft, S. M., Pollack, M. H., et al. (2019) · PLoS ONE · doi:10.1371/journal.pone.0223729 · Cited by 27
Self-citationPharmacotherapy of Anxiety Disorders: Current and Emerging Treatment Options
Garakani, A., Murrough, J. W., Freire, R. C. R., Thom, R. P., Larkin, K., Buono, F. D., & Iosifescu, D. V. (2021) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/appi.focus.19203 · Cited by 29
Nauphal, M., Swetlitz, C., Smith, L. M., & Rosellini, A. J. (2021) · Cognitive and Behavioral Practice · doi:10.1016/j.cbpra.2021.04.011 · Cited by 24
Early effects of exposure-based cognitive behaviour therapy on the neural correlates of anxiety
Reinecke, A., Thilo, K. V., Croft, A. J., & Harmer, C. J. (2018) · Translational Psychiatry · doi:10.1038/s41398-018-0277-5 · Cited by 21
New Developments in Cognitive-Behavioral Therapy for Social Anxiety Disorder
Stangier, U. (2016) · Current Psychiatry Reports · doi:10.1007/s11920-016-0667-4 · Cited by 21
Reinecke, A., Nickless, A., Browning, M. D., & Harmer, C. J. (2020) · Behaviour Research and Therapy · doi:10.1016/j.brat.2020.103607 · Cited by 20
Hofmeijer-Sevink, M. K., Duits, P., Rijkeboer, M. M., Hoogendoorn, A. W., van Megen, H. J. G. M., Vulink, N. C. C., Denys, D. A. J. P., van den Hout, M., van Balkom, A. J. L. M., & Cath, D. C. (2017) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0000000000000757 · Cited by 22
Finnegan, S., Browning, M. D., Duff, E. P., Harmer, C. J., Reinecke, A., Rahman, N. M., & Pattinson, K. T. S. (2022) · Thorax · doi:10.1136/thorax-2022-218754 · Cited by 18
Tuerk, P. W., Mcguire, J. F., & Piacentini, J. C. (2023) · Behavior Therapy · doi:10.1016/j.beth.2023.07.005 · Cited by 19
Reinecke, A., & Harmer, C. J. (2015) · Psychopathology Review · doi:10.5127/pr.035113 · Cited by 13
D-Cycloserine Facilitates Reversal in an Animal Model of Post-traumatic Stress Disorder
George, S. A., Rodriguez-Santiago, M., Riley, J., Abelson, J. L., Floresco, S., & Liberzon, I. (2018) · Behavioural Brain Research · doi:10.1016/j.bbr.2018.03.037 · Cited by 15
Sudden gains in internet-based cognitive behavior therapy for obsessive-compulsive disorder
Hamdeh, A. A., Bjureberg, J., Lenhard, F., Hedman‐Lagerlöf, E., Flygare, O., Lundström, L., Ljótsson, B., Mataix‐Cols, D., Rück, C., & Andersson, E. (2018) · Journal of Obsessive-Compulsive and Related Disorders · doi:10.1016/j.jocrd.2018.12.005 · Cited by 15
Wilhelm, S., Berman, N. C., Small, B. J., Porth, R., Storch, E. A., & GELLER, D. A. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.07.042 · Cited by 14
Pyrkosch, L., Mumm, J., Alt, I., Fehm, L., Fydrich, T., Plag, J., & Ströhle, A. (2018) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2018.08.016 · Cited by 14
Transcriptional Regulation Involved in Fear Memory Reconsolidation
Wang, X., Li, M., Zhu, H., Yu, Y., Xu, Y., Zhang, W., & Bian, C. (2018) · Journal of Molecular Neuroscience · doi:10.1007/s12031-018-1084-4 · Cited by 14
A transdiagnostic meta-analysis of acute augmentations to psychological therapy
Nord, C. L., Longley, B. F., Dercon, Q., Phillips, V., Funk, J., Gormley, S., Knight, R., Smith, A., & Dalgleish, T. (2023) · Nature Mental Health · doi:10.1038/s44220-023-00048-6 · Cited by 15
Advances in Psychopharmacology for Anxiety Disorders
Garakani, A., Murrough, J. W., & Iosifescu, D. V. (2014) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/appi.focus.12.2.152 · Cited by 13
Caetano, K. A. S., Depreeuw, B., Papenfuss, I., Curtiss, J., Langwerden, R. J., Hofmann, S. G., & Neufeld, C. B. (2018) · International Journal of Cognitive Therapy · doi:10.1007/s41811-018-0028-7 · Cited by 11
Self-citationSiddik, M. A. B., & Fendt, M. (2022) · Behavioural Brain Research · doi:10.1016/j.bbr.2022.113961 · Cited by 12
Looking Beyond Fear and Extinction Learning: Considering Novel Treatment Targets for Anxiety
Britton, J. C., Evans, T. C., & Hernandez, M. V. (2014) · Current Behavioral Neuroscience Reports · doi:10.1007/s40473-014-0015-0 · Cited by 11
d-Cycloserine-Augmented Behavior Therapy for Body Dysmorphic Disorder: A Preliminary Efficacy Trial
Weingarden, H. M., Mothi, S. S., Ladis, I., Hoeppner, S. S., Reese, H. E., Timpano, K. R., Siev, J., Rasmussen, J. L., Ragan, J. D., Dougherty, D. D., et al. (2019) · Cognitive Therapy and Research · doi:10.1007/s10608-019-10015-0 · Cited by 7
Schrödinger’s Cat and d -Cycloserine to Augment Exposure Therapy—Both Are Alive and Dead
Hofmann, S. G. (2016) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2016.1132 · Cited by 8
Self-citationNew advances in small molecule drugs targeting NMDA receptors
Zeng, Y., Qu, Z.-Y., Zhu, Q., Wang, H., Zhou, Y., & Gao, Z.-B. (2025) · Acta Pharmacologica Sinica · doi:10.1038/s41401-025-01675-8 · Cited by 8
Asnaani, A., Kaczkurkin, A. N., Tannahill, H. S., & Fitzgerald, H. E. (2016) · Journal of Experimental Psychopathology · doi:10.5127/jep.055416 · Cited by 8
Chapter 50. Treatment of Anxiety Disorders
Choi, S., & Stein, M. B. (2024) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615375523.as50 · Cited by 7
Javitt, D. C. (2013) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2013.13040503 · Cited by 7
Chen, S., Yan, L., Zeng, J., Meng, W., Zhuang, J., Chen, F., Guo, Y., El‐Aty, A. M. A., Ju, X., & Yang, S. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.115209 · Cited by 6
Byrne, S., Farrell, L. J., Storch, E. A., & Rapee, R. M. (2014) · Psychopathology Review · doi:10.5127/pr.033013 · Cited by 6
The Nature and Treatment of Social Anxiety
Carpenter, J. K., Curtiss, J. E., & Hofmann, S. G. (2017) · Wiley eBooks · doi:10.1002/9781118877142.ch5 · Cited by 6
Self-citationSmits, J. A. J., Zvolensky, M. J., Otto, M. W., Piper, M. E., Baird, S. O., Kauffman, B. Y., Lee-Furman, E., Alavi, N., Dutcher, C. D., Papini, S., et al. (2020) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2020.107877 · Cited by 5
Self-citationRozen, N., & Aderka, I. M. (2020) · Clinical Psychology Review · doi:10.1016/j.cpr.2020.101874 · Cited by 5
Kappelmann, N., Suesse, M., Steudte‐Schmiedgen, S., Kaldewaij, R., Browning, M. D., Michael, T., Rinck, M., & Reinecke, A. (2019) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/j.jbtep.2019.101546 · Cited by 5
Weems, C. F., & Neill, E. L. (2020) · Current Treatment Options in Psychiatry · doi:10.1007/s40501-020-00206-y · Cited by 5
Roque, A. D., Rosenfield, D., Smits, J. A. J., Simon, N. M., Otto, M. W., Marques, L. M., Pollack, M. H., Hofmann, S. G., & Meuret, A. E. (2017) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2017.11.004 · Cited by 5
Self-citationLedley, D. R., Erwin, B. A., Morrison, A. S., & Heimberg, R. G. (2017) · Psychopathology · doi:10.1002/9781394258949.ch2 · Cited by 5
Mechanisms of Action in the Treatment of Social Anxiety Disorder
Otto, M. W., Safren, S. A., & Hearon, B. A. (2014) · Social Anxiety · doi:10.1016/b978-0-12-394427-6.00027-3 · Cited by 5
Self-citationCurrent Treatments for Anxiety and Obsessive-Compulsive Disorders
Sayed, S., Horn, S. R. G.-V., & Murrough, J. W. (2014) · Current Treatment Options in Psychiatry · doi:10.1007/s40501-014-0020-7 · Cited by 4
A Comparison between Psychosocial and Pharmacological Treatments
Powers, M. B., Kauffman, B. Y., Diamond, A., & Smits, J. A. J. (2014) · Social Anxiety · doi:10.1016/b978-0-12-394427-6.00026-1 · Cited by 3
Self-citationPyrkosch, L., Lautenbacher, L. M., Mumm, J., Plag, J., Fehm, L., Fydrich, T., & Ströhle, A. (2024) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2024.10.018 · Cited by 3
Fehm, L., & Knappe, S. (2020) · Springer eBooks · doi:10.1007/978-3-662-61814-1_49 · Cited by 3
Carpenter, J. K., Conroy, K., & Hofmann, S. G. (2018) · Cambridge University Press eBooks · doi:10.1017/9781108140416.029 · Cited by 5
Self-citationSheerin, C. M., Kozak, A. T., Hale, A. C., Ramesh, B. K., & Spates, C. R. (2016) · Behavior Analysis Research and Practice · doi:10.1037/bar0000054 · Cited by 3
Metadata
- Authors
- Hofmann, S. G., Smits, J. A. J., Rosenfield, D., Simon, N., Otto, M. W., Meuret, A. E., Marques, L., Fang, A., Tart, C., & Pollack, M. H.
- Affiliations
- Boston University (US)
- Corresponding author
- Hofmann, Stefan G.
- ORCID
- Venue
- American Journal of Psychiatry
- Published
- 2013-07
- Volume
- 170
- Issue
- 7
- Pages
- 751-758
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- PMC
- PMC4058999
- OpenAlex
- W2169145652
- Cited by
- 121
- References
- 40
- Citations by year
- 2025: 4 · 2024: 5 · 2023: 6 · 2022: 2 · 2021: 2 · 2020: 9 · 2019: 5 · 2018: 15 · 2017: 11 · 2016: 10 · 2015: 22 · 2014: 20 · 2013: 10
- FWCI
- 27.92
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- National Institute of Mental Health (R01MH075889, K23MH096029, R01MH078308)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Keywords
- D-cycloserine, social anxiety disorder, generalized anxiety disorder, cognitive behavioral therapy, augmentation therapy, NMDA receptor partial agonist, exposure therapy, treatment response and remission
- MeSH terms
- Adult, Combined Modality Therapy, Cycloserine, Female, Humans, Interview, Psychological, Male, Phobic Disorders, Psychiatric Status Rating Scales, Remission Induction, Cognitive Behavioral Therapy, Receptors, N-Methyl-D-Aspartate
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
