Do depressive symptoms affect the outcome of treatments for SAD? A meta analysis of randomized controlled trials
Abstract
Individuals with social anxiety disorder (SAD) typically have elevated depressive symptoms. In the present meta-analysis, we reviewed the treatment outcome literature in SAD and examined whether depressive symptoms predict treatment outcome. We focused on randomized controlled trials of cognitive behavior therapy (individual face-to-face, group format, and internet-delivered format) and randomized controlled trials of pharmacotherapy. After implementing exclusion criteria, 108 studies with 133 treatment conditions (n = 12,913 participants) were included in the meta-analysis. Our findings indicated that treatments for SAD were efficacious and significantly reduced social anxiety symptoms across all treatment modalities. Exclusion of individuals with MDD or high levels of depression did not affect outcome at post-treatment or at follow-up. However, we found that elevated depressive symptoms were associated with greater reductions in social anxiety symptoms from pre-treatment to post-treatment. Importantly, this effect was above and beyond pre-treatment levels of social anxiety. Finally, analyzing treatment modalities separately, we found that depressive symptoms were associated with better post-treatment outcomes in individual face-to-face CBT but not in other modalities. Clinical and research implications of these findings are discussed.
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Recent meta-analyses suggested that depressive symptoms or a depressive disorder diagnosis do not adversely affect outcomes of treatments for social anxiety disorder.
“recent meta-analyses suggested that depressive symptoms or a depressive disorder diagnosis do not adversely affect outcomes of treatments for social anxiety disorder”
From Cognitive behavioural therapy for social anxiety disorder in people with bipolar disorder: a case series (2024) · cites this paper as Rozen and Aderka 2020
Our finding that individual CBT is effective in treating social anxiety in people with bipolar disorder is in line with previous findings on treatments for social anxiety disorder in people with unipolar depression.
“Our finding that individual CBT is effective in treating social anxiety in people with bipolar disorder is in line with previous findings on treatments for social anxiety disorder in people with unipolar depression”
From Cognitive behavioural therapy for social anxiety disorder in people with bipolar disorder: a case series (2024) · cites this paper as Rozen and Aderka 2020
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Zika, M. A., & Becker, L. (2021) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2021.653108 · Cited by 39 · see citing works
“Social anxiety disorder often occurs comorbidly with other psychiatric disorders, such as depression and substance dependency (Ruscio et al., 2008; Ohayon and Schatzberg, 2010; Stein et al., 2017; Prior et al., 2019; Rozen and Aderka, 2020).”
BackgroundRozen, N., & Aderka, I. M. (2021) · Cognitive Behaviour Therapy · doi:10.1080/16506073.2021.1966089 · Cited by 14 · see citing works
“This effect is partly consistent with Rozen and Aderka (2020) who found that the depression-outcome association was significant for individual, face-to-face CBT but not other modalities.”
BackgroundMethodResultInfluentialSelf-citationErceg-Hurn, D. M., Campbell, B. N. C., & McEvoy, P. M. (2023) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2023.102676 · Cited by 13 · see citing works
Pavlova, B., Warnock-Parkes, E., Alda, M., Uher, R., & Clark, D. M. (2024) · International Journal of Bipolar Disorders · doi:10.1186/s40345-023-00321-8 · Cited by 5 · see citing works
“…suggested that depressive symptoms or a depressive disorder diagnosis do not adversely affect outcomes of treatments for social anxiety disorder and that in individual CBT people with major depressive disorder may have outcomes superior to those without a mood disorder (Rozen and Aderka 2020).”
BackgroundBowers, E. M., Peckham, A., Goodman, F. R., Hom, M. A., Beckham, E. E., Björgvinsson, Þ., & Beard, C. (2023) · Depression and Anxiety · doi:10.1155/2023/7614830 · Cited by 5 · see citing works
- Authors
- Rozen, N., & Aderka, I. M.
- Affiliations
- University of Haifa (IL)
- Corresponding author
- Aderka, Idan M.
- Venue
- Clinical Psychology Review
- Publisher
- Elsevier BV
- Published
- 2020-08
- Volume
- 80
- Pages
- 101874
- ISSN
- 0272-7358 (ISSN-L)
- OpenAlex
- W3033778489
- Cited by
- 5
- References
- 227
- Citations by year
- 2024: 1 · 2023: 2 · 2021: 2
- FWCI
- 0.15
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Psychology Review (publishedVersion)
- PubMed (publishedVersion)
- Funders
- University of Haifa
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Clinical Psychology › Psychological Treatments and Assessments
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Keywords
- social anxiety disorder, depressive symptoms, treatment outcomes, cognitive behavioral therapy, group cognitive behavioral therapy, pharmacotherapy, major depressive disorder, comorbidities, treatment response
- MeSH terms
- Phobia, Social, Adult, Depression, Female, Humans, Male, Cognitive Behavioral Therapy, Randomized Controlled Trials as Topic, Treatment Outcome
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