The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Oxidative Stress, Systemic Inflammation, and Severe Periodontitis
Open accessAbstract
Periodontal infections have been associated with a state of chronic inflammation. To ascertain whether severe periodontitis and its treatment are associated with oxidative stress, we recruited 145 cases (periodontitis) and 56 controls in a case-control study. A further pilot intervention study of 14 cases (periodontal therapy) was performed. Blood samples were taken at baseline (case-control) and 1, 3, 5, 7, and 30 days after treatment (intervention). Diacron-reactive oxygen metabolites (D-ROM), anti-oxidant potential, C-reactive protein (CRP), interleukin-6, and lipid profiles were determined with high-sensitivity assays in serum. Patients with severe periodontitis exhibited higher D-ROM levels (P < 0.001) and lower total anti-oxidant capacity (P < 0.001) compared with healthy control individuals. These findings were independent of age, gender, smoking habits, ethnicity, and standard lipids differences. D-ROM levels were positively correlated with CRP (R = 0.4, P < 0.001) and clinical periodontal parameters (R = 0.20, P < 0.05). Acute increases of D-ROM (P < 0.01) were observed following periodontal therapy. Analysis of these data suggests a positive association between severe periodontitis and oxidative stress.
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Pihlstrom, B. L., Michalowicz, B. S., & Johnson, N. W. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67728-8 · Cited by 3,522
Treatment of periodontitis and endothelial function
Tonetti, M. S., D'Aiuto, F., Nibali, L., Donald, A., Storry, C., Parkar, M., Suvan, J., Hingorani, A. D., Vallance, P., & Deanfield, J. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa063186 · Cited by 1,326
Self-citationThe role of reactive oxygen and antioxidant species in periodontal tissue destruction
Chapple, I. L. C., & Matthews, J. B. (2007) · Periodontology 2000 · doi:10.1111/j.1600-0757.2006.00178.x · Cited by 936
Bacteremia Associated With Toothbrushing and Dental Extraction
Lockhart, P. B., Brennan, M. T., Sasser, H. C., Fox, P. C., Paster, B. J., & Bahrani-Mougeot, F. K. (2008) · Circulation · doi:10.1161/circulationaha.107.758524 · Cited by 851
A systematic review and meta‐analyses on C‐reactive protein in relation to periodontitis
Paraskevas, S., Huizinga, J. D., & Loos, B. G. (2008) · Journal of Clinical Periodontology · doi:10.1111/j.1600-051x.2007.01173.x · Cited by 757
D’Aiuto, F., Parkar, M., Andreou, G., Suvan, J., Brett, P. M., Ready, D., & Tonetti, M. S. (2004) · Journal of Dental Research · doi:10.1177/154405910408300214 · Cited by 746
Self-citationReactive oxygen and nitrogen species as signaling molecules regulating neutrophil function
Fialkow, L., Wang, Y., & Downey, G. P. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2006.09.030 · Cited by 708
Hyslop, P. A., Hinshaw, D. B., Halsey, W. A., Schraufstätter, I. U., Sauerheber, R. D., Spragg, R. G., Jackson, J. H., & Cochrane, C. G. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)77928-9 · Cited by 616
Short-term Effects of Intensive Periodontal Therapy on Serum Inflammatory Markers and Cholesterol
D’Aiuto, F., Nibali, L., Parkar, M., Suvan, J., & Tonetti, M. S. (2005) · Journal of Dental Research · doi:10.1177/154405910508400312 · Cited by 416
Self-citationConsensus Report: Aggressive Periodontitis
Lang, N., Bartold, P. M., Cullinan, M., Jeffcoat, M., Mombelli, A., Murakami, S., Page, R., Papapanou, P., Tonetti, M., & Van Dyke, T. (1999) · Annals of Periodontology · doi:10.1902/annals.1999.4.1.53 · Cited by 378
Cited by
National Health and Nutrition Examination Survey
(2010) · Handbook of Disease Burdens and Quality of Life Measures · doi:10.1007/978-0-387-78665-0_6177 · Cited by 2,087
Periodontal Inflammation and Systemic Diseases: An Overview
Martínez-García, M., & Hernández-Lemus, E. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.709438 · Cited by 512
A review of the evidence for pathogenic mechanisms that may link periodontitis and diabetes
Taylor, J. J., Preshaw, P. M., & Lalla, E. (2013) · Journal of Clinical Periodontology · doi:10.1111/jcpe.12059 · Cited by 425
Orlandi, M., Suvan, J., Petrie, A., Donos, N., Masi, S., Hingorani, A., Deanfield, J., & D’Aiuto, F. (2014) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2014.06.002 · Cited by 164
Serum C-Reactive Protein and Periodontitis: A Systematic Review and Meta-Analysis
Machado, V., Botelho, J., Escalda, C., Hussain, S. B., Luthra, S., Mascarenhas, P., Orlandi, M., Mendes, J. J., & D’Aiuto, F. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.706432 · Cited by 160
Self-citation
Metadata
- Authors
- D’Aiuto, F., Nibali, L., Parkar, M., Patel, K., Suvan, J., & Donos, N.
- Venue
- Journal of Dental Research
- Publisher
- SAGE Publications
- Published
- 2010-08-25
- Volume
- 89
- Issue
- 11
- Pages
- 1241-1246
- ISSN
- 0022-0345 (ISSN-L)
- 1544-0591
- OpenAlex
- W1976102373
- Cited by
- 356
- References
- 28
- FWCI
- 23.41
- Type
- journal article
- Language
- en
- Open access
- green
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