Oxidative Stress
Abstract
Oxidative stress is defined by an imbalance between increased levels of reactive oxygen species (ROS) and a low activity of antioxidant mechanisms. An increased oxidative stress can induce damage to the cellular structure and potentially destroy tissues. However, ROS are needed for adequate cell function, including the production of energy by the mitochondria. Increased oxidative stress has been incriminated in physiological conditions, such as aging and exercise, and in several pathological conditions, including cancer, neurodegenerative diseases, cardiovascular diseases, diabetes, inflammatory diseases, and intoxications. However, prevention by antioxidants has been mostly inefficient. Therefore, a rigorous scientific evaluation in well‐defined conditions is mandatory to define the appropriate place for manipulations of the oxidative pathways in human medicine.
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The studies on fish oil enriched intravenous lipid emulsion showed heterogeneity and had low sample size.
“but the studies showed heterogeneity and had low sample size.”
From ESPEN guideline on clinical nutrition in the intensive care unit. (2019) · cites this paper as [275]
Tao et al. found a reduction in mechanical ventilation days in septic patients receiving fish oil enriched intravenous lipid emulsion.
“Tao et al. (275) found a reduction in mechanical ventilation days in septic patients receiving fish oil enriched intravenous lipid emulsion”
From ESPEN guideline on clinical nutrition in the intensive care unit. (2019) · cites this paper as [275]
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Self-citation
- Authors
- Preiser, J.
- Affiliations
- Erasmus Hospital (BE)
- Corresponding author
- Preiser, Jean‐Charles
- Venue
- Journal of Parenteral and Enteral Nutrition
- Publisher
- Wiley
- Published
- 2012-02
- Volume
- 36
- Issue
- 2
- Pages
- 147-154
- ISSN
- 0148-6071 (ISSN-L)
- 1941-2444
- OpenAlex
- W4246769188
- Cited by
- 236
- References
- 43
- Citations by year
- 2026: 29 · 2025: 43 · 2024: 35 · 2023: 30 · 2022: 21 · 2021: 14 · 2020: 14 · 2019: 5 · 2018: 6 · 2017: 9 · 2016: 9 · 2015: 6 · 2014: 8 · 2013: 5 · 2012: 2
- FWCI
- 4.68
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Journal of Parenteral and Enteral Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Dépôt institutionnel de l'Université libre de Bruxelles (Université Libre de Bruxelles) (submittedVersion)
- Topics
- Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
- Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Redox biology and oxidative stress
- Keywords
- oxidative stress, reactive oxygen species, antioxidants, mitochondrial energy production, aging, physical activity, cancer, neurodegenerative diseases, cardiovascular disease, diabetes mellitus, inflammation, poisoning, antioxidant therapy
- MeSH terms
- Antioxidants, Humans, Oxidation-Reduction, Reactive Oxygen Species, Oxidative Stress
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