Treating Nonsuicidal Self-Injury: A Systematic Review of Psychological and Pharmacological Interventions
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Objective: Nonsuicidal self-injury (NSSI), the deliberate, self-inflicted damage of bodily tissue without the intent to die, is associated with various negative outcomes. Although basic and epidemiologic research on NSSI has increased during the last 2 decades, literature on effective interventions targeting NSSI is still emerging. Here, we present a comprehensive, systematic review of existing psychological and pharmacological treatments designed specifically for NSSI, or including outcome assessments examining change in NSSI. Method: We conducted a systematic search of PsycINFO, MEDLINE, and ERIC databases to retrieve relevant articles that met inclusion criteria; specifically, uncontrolled and controlled trials that 1) presented quantitative outcome data on NSSI, and 2) clearly differentiated NSSI from suicidal self-injury (SSI). Consistent with the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, definition of NSSI, we excluded studies examining populations with developmental or intellectual disabilities, or with psychotic disorders. Results: Several interventions appear to hold promise for reducing NSSI, including dialectical behaviour therapy, emotion regulation group therapy, manual-assisted cognitive therapy, dynamic deconstructive psychotherapy, atypical antipsychotics (aripiprazole), naltrexone, and selective serotonin reuptake inhibitors (with or without cognitive-behavioural therapy). Nevertheless, there remains a paucity of well-controlled studies investigating treatment efficacy for NSSI. Conclusions: Structured psychotherapeutic approaches focusing on collaborative therapeutic relationships, motivation for change, and directly addressing NSSI behaviours seem to be most effective in reducing NSSI. Medications targeting the serotonergic, dopaminergic and opioid systems also have demonstrated some benefits. Future studies employing controlled designs as well as a clear delineation of NSSI and SSI will improve knowledge regarding treatment effects.
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Turner et al.'s (2014) systematic review of non-suicidal self-injury concluded that structure and collaboration were the most effective components of treatment, but did not identify a clear front runner in psychological interventions.
“In their systematic review of non-suicidal self-injury, Turner et al. (2014) concluded that structure and collaboration were the most effective components of treatment, but did not identify a clear front runner in psychological interventions.”
From A multi‐method evaluation of a compassion‐focused cognitive behavioural psychotherapy group for people who self‐harm. (2022) · cites this paper as Turner et al. (2014)
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“This is consistent with recent meta-analytical findings on adolescents (Ougrin et al., 2015), although qualitatively contrasting results have been reported (Turner et al., 2014).”
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“Medications targeting the serotonergic, dopaminergic and opioid systems also have demonstrated some bene fi ts (Turner et al. 2014).”
BackgroundInfluentialTurner, B. J., Cobb, R. J., Gratz, K. L., & Chapman, A. L. (2016) · Journal of Abnormal Psychology · doi:10.1037/abn0000141 · Cited by 154 · see citing works
Self-citationLifetime and 12-Month Nonsuicidal Self-Injury and Academic Performance in College Freshmen.
Kiekens, G., Claes, L., Demyttenaere, K., Auerbach, R., Green, J., Kessler, R., Mortier, P., Nock, M., & Bruffaerts, R. (2016) · Suicide and Life-Threatening Behaviour · doi:10.1111/sltb.12237 · Cited by 102 · see citing works
Pharmacological interventions for self-harm in adults
Hawton, K. E., Witt, K., Salisbury, T. T., Arensman, E., Gunnell, D., Hazell, P., Townsend, E., & van Heeringen, K. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011777 · Cited by 82 · see citing works
Buelens, T., Luyckx, K., Gandhi, A., Kiekens, G., & Claes, L. (2019) · Research on Child and Adolescent Psychopathology · doi:10.1007/s10802-019-00531-8 · Cited by 119 · see citing works
Bjureberg, J., Sahlin, H., Hedman-Lagerlöf, E., Gratz, K. L., Tull, M. T., Jokinen, J., Hellner, C., & Ljótsson, B. (2018) · BMC Psychiatry · doi:10.1186/s12888-018-1885-6 · Cited by 96 · see citing works
Arshad, U., Farhat-ul-Ain, F.-U., Gauntlett, J., Husain, N., Chaudhry, N., & Taylor, P. J. (2019) · Suicide and Life-Threatening Behavior · doi:10.1111/sltb.12583 · Cited by 118 · see citing works
“Rates of initial engagement with therapy Web sites were high (88%–92% starting the intervention; van Spijker et al., 2018, 2014) but fewer accessed at least three of the six modules (44%–56%).”
BackgroundBjureberg, J., Sahlin, H., Hellner, C., Hedman-Lagerlöf, E., Gratz, K. L., Bjärehed, J., Jokinen, J., Tull, M. T., & Ljótsson, B. (2017) · BMC Psychiatry · doi:10.1186/s12888-017-1527-4 · Cited by 84 · see citing works
“In a recent systematic review of treatments for NSSI in both adolescent and adult populations [12], the authors concluded that the psychological treatments that show promise in reducing NSSI frequency are dialectical behavior therapy [13], emotion regulation group therapy (ERGT; [14]), manual-assisted cognitive therap…”
BackgroundRobinson, K., Garisch, J. A., Kingi, T., Brocklesby, M., O’Connell, A., Langlands, R. L., Russell, L., & Wilson, M. S. (2018) · Journal of Abnormal Child Psychology · doi:10.1007/s10802-018-0450-6 · Cited by 79 · see citing works
Self-injury recovery: A person-centered framework.
Lewis, S. P., & Hasking, P. A. (2020) · Journal of Clinical Psychology · doi:10.1002/jclp.23094 · Cited by 67 · see citing works
Bentley, K. H., Nock, M., Sauer-Zavala, S., Gorman, B., & Barlow, D. (2017) · Journal of Consulting and Clinical Psychology · doi:10.1037/ccp0000205 · Cited by 65 · see citing works
“Existing cognitive–behavioral treatments for NSSI also contain many components, making it difficult to define the specific ingredients responsible for improvements when they occur (e.g., Lynch & Cozza, 2009; Turner et al., 2014).”
BackgroundKaess, M., Edinger, A., Fischer-Waldschmidt, G., Parzer, P., Brunner, R. M., & Resch, F. (2019) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-019-01399-1 · Cited by 89 · see citing works
Molero, Y., Zetterqvist, J., Binswanger, I. A., Hellner, C., Larsson, H., & Fazel, S. (2018) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2018.17101112 · Cited by 60 · see citing works
“However, our findings here, which are consistent with a small body of trial evidence regarding the use of naltrexone and buprenorphine (20, 21), suggest enhancing the timely and appropriate prescription of opioid medications as an important strategy to reduce adverse outcomes related to opioid use disorder.”
ResultExperiencing and Resisting Nonsuicidal Self‐injury Thoughts and Urges in Everyday Life
Turner, B. J., Baglole, J. S., Chapman, A. L., & Gratz, K. L. (2019) · Suicide and Life-Threatening Behavior · doi:10.1111/sltb.12510 · Cited by 57 · see citing works
Self-citationKelada, L., Hasking, P. A., Melvin, G., Whitlock, J., & Baetens, I. (2018) · Journal of Adolescent Research · doi:10.1177/0743558416684954 · Cited by 54 · see citing works
Non-Suicidal Self-Injury and Eating Disordered Behaviors: An Update on What We Do and Do Not Know
Kiekens, G., & Claes, L. (2020) · Current Psychiatry Reports · doi:10.1007/s11920-020-01191-y · Cited by 53 · see citing works
Understanding self‐injury recovery: Views from individuals with lived experience
Lewis, S. P., Kenny, T. E., Whitfield, K. M., & Gomez, J. (2019) · Journal of Clinical Psychology · doi:10.1002/jclp.22834 · Cited by 63 · see citing works
The relationship between rumination and NSSI: A systematic review and meta-analysis.
Coleman, S. E., Dunlop, B., Hartley, S., & Taylor, P. (2021) · British Journal of Clinical Psychology · doi:10.1111/bjc.12350 · Cited by 50 · see citing works
An intervention for nonsuicidal self-injury in young adults: A pilot randomized controlled trial.
Andover, M. S., Schatten, H. T., Morris, B. W., Holman, C. S., & Miller, I. W. (2017) · Journal of Consulting and Clinical Psychology · doi:10.1037/ccp0000206 · Cited by 58 · see citing works
“…Andover & Morris, 2014), as well as the effectiveness of DBT, which targets emotion regulation skills, in treating the behavior, suggests that interventions focusing on building emotion regulation strategies may be particularly useful in the treatment of NSSI (Gratz, 2007; Turner et al., 2014).”
InfluentialSinyor, M., Williams, M., Mitchell, R. H. B., Zaheer, R., Bryan, C. J., Schaffer, A., Westreich, N., Ellis, J., Goldstein, B. I., Cheung, A., et al. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.01.178 · Cited by 54 · see citing works
Buelens, T., Costantini, G., Luyckx, K., & Claes, L. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.580922 · Cited by 45 · see citing works
“Noteworthy, previous research has shown that teaching coping skills to reduce and resist frequent NSSI thoughts and urges is a key component of successful treatment for NSSI (78, 79).”
BackgroundGetting “clean” from nonsuicidal self-injury: Experiences of addiction on the subreddit r/selfharm
Himelein-Wachowiak, M., Giorgi, S., Kwarteng, A., Schriefer, D., Smitterberg, C. W., Yadeta, K., Bragard, E., Devoto, A., Kulkarni, P. V., & Curtis, B. L. (2022) · Journal of Behavioral Addictions · doi:10.1556/2006.2022.00005 · Cited by 44 · see citing works
“Dialectical behavior therapy (DBT) may be the most effective treatment for reducing NSSI (Elmaghraby, Nobari, & Cullen, 2019), although its efficacy is mixed, and studies are often limited to populations with BPD (Turner et al., 2014).”
BackgroundHe, H., Hong, L., Jin, W., Xu, Y., Kang, W., Liu, J., Song, J.-Y., Zheng, T., Chen, H., & Zhao, K. (2023) · BMC Psychiatry · doi:10.1186/s12888-023-04808-7 · Cited by 41 · see citing works
Per, M., Schmelefske, E., Brophy, K., Austin, S. B., & Khoury, B. (2022) · Mindfulness · doi:10.1007/s12671-021-01815-1 · Cited by 46 · see citing works
Self-citationGuo, J., Gao, Q., Wu, R., Ying, J., & You, J. (2021) · Archives of Suicide Research · doi:10.1080/13811118.2021.1922109 · Cited by 42 · see citing works
Psychotherapeutic interventions for the prevention of suicide re-attempts: a systematic review
Sobanski, T., Josfeld, S., Peikert, G., & Wagner, G. (2021) · Psychological Medicine · doi:10.1017/s0033291721003081 · Cited by 37 · see citing works
A meta-analysis of the effects of ketamine on suicidal ideation in depression patients
Shen, Z., Gao, D., Lv, X., Wang, H., & Yue, W. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-02973-1 · Cited by 41 · see citing works
Thoughts, images, and appraisals associated with acting and not acting on the urge to self-injure.
McEvoy, P. M., Hayes, S., Hasking, P. A., & Rees, C. S. (2017) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/j.jbtep.2017.05.010 · Cited by 34 · see citing works
Position paper for guiding response to non-suicidal self-injury in schools
Hasking, P. A., Heath, N. L., Kaess, M., Lewis, S. P., Plener, P. L., Walsh, B. W., Whitlock, J. L., & Wilson, M. (2016) · School Psychology International · doi:10.1177/0143034316678656 · Cited by 43 · see citing works
“in emotion regulation), motivation for treatment, and a focus on improving family and other interpersonal relationships (Glenn et al., 2015; Turner et al., 2014).”
BackgroundPeters, E. M., Baetz, M., Marwaha, S., Balbuena, L., & Bowen, R. (2016) · Borderline Personality Disorder and Emotion Dysregulation · doi:10.1186/s40479-016-0051-3 · Cited by 33 · see citing works
“emphasizing emotional regulation such as dialectical behaviour therapy are effective at treating NSSI [34].”
BackgroundApicella, M., Pontillo, M., Maglio, G., Vincenzo, C. D., Santa, G. D., Andracchio, E., & Vicari, S. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1605508 · Cited by 37 · see citing works
Characterizing the choice to disclose nonsuicidal self-injury.
Ammerman, B. A., Wilcox, K., O'Loughlin, C. M., & McCloskey, M. (2020) · Journal of Clinical Psychology · doi:10.1002/jclp.23045 · Cited by 31 · see citing works
Kaess, M., Koenig, J., Bauer, S., Moessner, M., Fischer-Waldschmidt, G., Mattern, M., Herpertz, S. C., Resch, F., Brown, R. C., In‐Albon, T., et al. (2019) · Trials · doi:10.1186/s13063-019-3501-6 · Cited by 47 · see citing works
Correlates of Non-suicidal Self-Injury in Adolescent Psychiatric Patients in China
Zhang, J.-J., Liu, Y.-D., Zhang, H., Huang, Z., Wang, F., Yang, J.-J., Wang, S., Jia, F., & Hou, C.-L. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.864150 · Cited by 29 · see citing works
Rodante, D., Kaplan, M. I., Fedi, R. O., Gagliesi, P., Pascali, A., Quintero, P. S. J., Compte, E. J., Perez, A. I., Weinstein, M., Chiapella, L. C., et al. (2020) · Archives of Suicide Research · doi:10.1080/13811118.2020.1834476 · Cited by 37 · see citing works
Izadi-Mazidi, M., Yaghubi, H., Mohammadkhani, P., & Hassanabadi, H. (2019) · Iranian Journal of Psychiatry · doi:10.18502/ijps.v14i3.1319 · Cited by 22 · see citing works
“This prevalent behavior can result in serious physical consequences such as physical injury, infectious disease, medical complications, and death (6-9).”
BackgroundBentley, K. H., Maimone, J. S., Kilbury, E. N., Tate, M. S., Wisniewski, H., Levine, M., Roberg, R., Torous, J., Nock, M., & Kleiman, E. M. (2021) · Clinical Psychology Review · doi:10.1016/j.cpr.2021.102098 · Cited by 27 · see citing works
The Prevalence, Correlates and Functions of Non-Suicidal Self-Injury in Vietnamese Adolescents
Thai, T. T., Jones, M. K., Nguyễn, T. T. P., Pham, T. V., Bui, H. T. H., Kim, L. X., & Nguyen, T. V. (2021) · Psychology Research and Behavior Management · doi:10.2147/prbm.s339168 · Cited by 26 · see citing works
“Further, while there is a paucity of well-controlled studies examining treatment approaches to reduce NSSI a systematic review conducted by Turner et al 30 identified that both psychological and These included emotion regulation group therapy, dialectical behaviour therapy, manual-assisted…”
“Attempting to dull the dysphoria”: Nonsuicidal self-injury among transgender individuals.
Morris, E. R., & Galupo, M. P. (2019) · Psychology of Sexual Orientation and Gender Diversity · doi:10.1037/sgd0000327 · Cited by 26 · see citing works
Tan, S.-C., Tam, C., & Bonn, G. (2018) · Asia Pacific Journal of Counselling and Psychotherapy · doi:10.1080/21507686.2018.1541912 · Cited by 26 · see citing works
“This suggests that, in addition to developing emotion regulation skills, NSSI interventions should also focus on self-related cognitions (Turner et al., 2014).”
BackgroundHuang, X., Harris, L. M., Funsch, K. M., Fox, K., & Ribeiro, J. D. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-02173-9 · Cited by 25 · see citing works
Vieira, A. I., Moreira, C. S., Rodrigues, T. F., Brandão, I., Timóteo, S., Nunes, P., & Gonçalves, S. F. (2020) · Journal of Clinical Psychology · doi:10.1002/jclp.23038 · Cited by 24 · see citing works
A typology of nonsuicidal self‐injury in a clinical sample: A latent class analysis
Shahwan, S., Lau, J.-H., Abdin, E., Zhang, Y.-J., Sambasivam, R., Teh, W. L., Gupta, B., Ong, S. H., Chong, S., & Subramaniam, M. (2020) · Clinical Psychology and Psychotherapy · doi:10.1002/cpp.2463 · Cited by 24 · see citing works
“, 2019) and skills training to strengthen interpersonal bonding and family relationships such as communication training, problemsolving and/or conflict management (Hetrick, Robinson, Spittal, & Carter, 2016; Turner et al., 2014).”
BackgroundGramaglia, C., Feggi, A., Bergamasco, P., Bert, F., Gattoni, E., Marangon, D., Siliquini, R., Torre, E., & Zeppegno, P. (2016) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2016.00109 · Cited by 24 · see citing works
“The small number of drugs for which there is empirical evidence of a reduction in non-suicidal self-injurious behavior includes some SSRIs and venlafaxine (36).”
Suicidal ideation and behaviour
Korczak, D. J., & Canadian Paediatric Society (2015) · Paediatrics & Child Health · doi:10.1093/pch/20.5.257 · Cited by 21 · see citing works
Nonsuicidal Self-Injury: Management on the Inpatient Psychiatric Unit
Timberlake, L. M., Beeber, L., & Hubbard, G. (2019) · Journal of the American Psychiatric Nurses Association · doi:10.1177/1078390319878878 · Cited by 22 · see citing works
“Pharmacological treatments for NSSI have included SSRIs (selective serotonin reuptake inhibitors), SNRIs (serotonin–norepinephrine reuptake inhibitors), atypical antipsychotics, opioids, and opioid antagonists (Bresin & Gordon, 2013; Norelli, Smith, Sher, & Blackwood, 2013; Turner et al., 2014).”
BackgroundInfluentialAndrei, L., Efrim-Budisteanu, M., Mihailescu, I., Buică, A., Moise, M., & Rad, F. (2024) · Children · doi:10.3390/children11030297 · Cited by 21 · see citing works
“Integrated treatments that target both NSSI and co-occurring psychiatric disorders, such as dialectical behaviour therapy (DBT) or cognitive-behavioural therapy (CBT), may be particularly effective in reducing self-harm behaviours and improving overall mental health outcomes [37–39].”
BackgroundMultimodal assessment of sustained threat in adolescents with nonsuicidal self-injury
Başgöze, Z., Mirza, S. A., Silamongkol, T., Hill, D. C., Falke, C. A., Thai, M., Schreiner, M. W., Parenteau, A. M., Roediger, D. J., Hendrickson, T. J., et al. (2021) · Development and Psychopathology · doi:10.1017/s0954579421000754 · Cited by 27 · see citing works
Dunlop, B. J., Hunter, C., Shafti, M., Coleman, S. E., Hartley, S., & Taylor, P. J. (2021) · Psychology and Sexuality · doi:10.1080/19419899.2021.1924241 · Cited by 18 · see citing works
“, 2016), Dialectical Behaviour Therapy (Turner et al., 2014) and emotion-regulation group therapy (Turner et al.”
BackgroundInfluentialSimonsson, O., Engberg, H., Bjureberg, J., Ljótsson, B., Stensils, J., Sahlin, H., & Hellner, C. (2020) · JMIR Formative Research · doi:10.2196/17910 · Cited by 20 · see citing works
“A total of 2 interview guides, 1 for the adolescents and 1 for the caregivers (Multimedia Appendices 1 and 2), were developed based on previous research (ie, on structure [49] and content [25,26,37,40]) and clinical experience and reviewed by the authors.”
BackgroundMethodResultHolth, F., Walby, F. A., Røstbakken, T., Lunde, I., Ringen, P. A., Ramleth, R., Romm, K. L., Tveit, T., Torgersen, T., Urnes, Ø., et al. (2018) · Nordic Journal of Psychiatry · doi:10.1080/08039488.2018.1511751 · Cited by 23 · see citing works
Johnson, B. N., McKernan, L. C., & Bruehl, S. P. (2022) · Current Pain and Headache Reports · doi:10.1007/s11916-022-01043-9 · Cited by 25 · see citing works
Koposov, R., Stickley, A., & Ruchkin, V. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.652004 · Cited by 19 · see citing works
Ward‐Ciesielski, E. F., Schumacher, J. A., & Bagge, C. L. (2016) · Crisis · doi:10.1027/0227-5910/a000400 · Cited by 18 · see citing works
Peterson, E. J., Worlein, J., Lee, G. H., Dettmer, A., Varner, E., & Novak, M. A. (2016) · American Journal of Primatology · doi:10.1002/ajp.22569 · Cited by 19 · see citing works
“…similar responses to treatment, for example, some efficacy with fluoxetine [Fontenot et al., 2009] and naltrexone [Kempf et al., 2012] in rhesus monkeys along with a meta-analysis of research on humans suggesting treatment efficacy with SSRIs, and naltrexone [see Turner et al., 2014 for a review].”
BackgroundBaer, M. M., LaCroix, J. M., Browne, J. C., Hassen, H. O., Perera, K. U., Soumoff, A., Weaver, J., & Ghahramanlou-Holloway, M. (2018) · Psychiatry Research · doi:10.1016/j.psychres.2018.08.082 · Cited by 18 · see citing works
Eggart, V., Cordier, S., Hasan, A., & Wagner, E. M. (2022) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-022-01385-w · Cited by 25 · see citing works
“Previous reviews evaluating treatment options of self-injurious behavior included either SH in adults and adolescents [22, 23] or NSSI in adolescents [24, 25] and reported the absence of evidence for effective pharmacological interventions to improve SH or NSSI.”
BackgroundLindquist, E. G., & West, A. E. (2021) · Clinical Psychological Science · doi:10.1177/21677026211049367 · Cited by 18 · see citing works
Non-Suicidal Self-Injury in Russian Patients with Suicidal Ideation
Зинчук, М. С., Beghi, M., Beghi, E., Bianchi, E., Аведисова, А. С., Yakovlev, A. A., & Guekht, A. B. (2020) · Archives of Suicide Research · doi:10.1080/13811118.2020.1833801 · Cited by 21 · see citing works
Clozapine Reduces Self-Injurious Behavior in a State Prison Population
Zarzar, T. R., Catlett, T. L., O'Connell, M. G., Harrelson, B. H., Wilson, V. P., Rashad, G. N., Morris, D. B., Williams, J. B., Peebles, S. S., & Sheitman, B. (2019) · The journal of the American Academy of Psychiatry and the Law · doi:10.29158/jaapl.003818-19 · Cited by 17 · see citing works
“Two recent reviews show limited effectiveness of pharmacological management of SIB in adults in non-correctional settings; however, these reviews relied exclusively on randomized trials and did not include clozapine.(13,14) Clozapine is a second-generation antipsychotic medication with demonstrated effectiveness for t…”
BackgroundRoley‐Roberts, M. E., Zielinski, M. J., Hurtado, G., Hovey, J. D., & Elhai, J. D. (2016) · Suicide and Life-Threatening Behavior · doi:10.1111/sltb.12306 · Cited by 15 · see citing works
Neural mechanisms and neuromodulation therapies for non-suicidal self-injury
Wu, D., Wang, S., Wang, H., Zhang, J., & Tian, Y. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-03125-7 · Cited by 17 · see citing works
“Current treatment approaches primarily involve pharmacotherapy [8, 9] and psychotherapy [10 – 12], but their ef fi cacy is limited, and effective, targeted treatments are lacking.”
Chen, X., Dong, Y., Ye, M., Wang, X., Yan, J., Yao, Y., Zhou, Q., Qian, C., & Liu, Z. (2025) · BMC Psychiatry · doi:10.1186/s12888-025-06735-1 · Cited by 17 · see citing works
A person-centred conceptualisation of non-suicidal self-injury recovery: a practical guide
Hasking, P. A., Lewis, S. P., & Tonta, K. E. (2023) · Counselling Psychology Quarterly · doi:10.1080/09515070.2023.2225045 · Cited by 18 · see citing works
“Here, dialectical behaviour therapy (DBT) may help given its use for NSSI more generally and its utility in fostering distress tolerance and coping with emotional pain (Turner, Austin, & Chapman, 2014).”
Dai, L., Zhang, X., Yu, R.-Q., Wang, X., Deng, F., Li, X., & Kuang, L. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1177227 · Cited by 16 · see citing works
“There remains a paucity of wellcontrolled studies investigating treatment efficacy of NSSI (16).”
BackgroundHamza, C., Robinson, K., Hasking, P. A., Heath, N., Lewis, S. P., Lloyd-Richardson, E. E., Whitlock, J., & Wilson, M. S. (2021) · Journal of American College Health · doi:10.1080/07448481.2021.1961782 · Cited by 16 · see citing works
“24,25 Should this training be unavailable, hosting professional development workshops or related opportunities for campus mental health professionals may be needed.”
BackgroundMethodInfluentialModerators of Treatment Response to an Intervention for Nonsuicidal Self-Injury in Young Adults
Andover, M. S., Schatten, H. T., Holman, C. S., & Miller, I. (2020) · Journal of Consulting and Clinical Psychology · doi:10.1037/ccp0000603 · Cited by 16 · see citing works
“Interventions demonstrating a decrease in NSSI have been identified among adolescents and adults (e.g., Glenn, Esposito, Porter, & Robinson, 2019; Turner et al., 2014), including dialectical behavior therapy (DBT; e.”
BackgroundResultInfluentialSelf-Injury as an Addictive Disorder.
Worley, J. A. (2020) · Journal of Psychosocial Nursing and Mental Health Services · doi:10.3928/02793695-20200513-03 · Cited by 16 · see citing works
The Development of a Measure to Assess Social Reactions to Self-Injury Disclosure
Ammerman, B. A., & McCloskey, M. S. (2020) · Assessment · doi:10.1177/1073191120903081 · Cited by 19 · see citing works
“When identified, NSSI can be reduced through psychological and pharmacological interventions (Andover et al., 2017; Bentley et al., 2017; Cook & Gorraiz, 2016; Turner et al., 2014).”
BackgroundTaylor, P., Fien, K., Mulholland, H., Duarte, R., Dickson, J. M., & Kullu, C. (2020) · Psychology and psychotherapy · doi:10.1111/papt.12277 · Cited by 15 · see citing works
“Whilst clinical trials support the efficacy of a number of psychological therapies for self-harm (Hawton et al., 2017; Hetrick et al., 2016; Turner et al., 2014), work is still needed to determine which approaches might be most effective and in which settings.”
BackgroundStudy of Risk Factors Associated with Suicide Attempt in Patients with Bipolar Disorder Type I
Subramanian, K., Menon, V., Sarkar, S., Chandrasekaran, V., & Selvakumar, N. (2020) · Journal of Neurosciences in Rural Practice · doi:10.1055/s-0040-1709347 · Cited by 15 · see citing works
Peters, E. M., John, A. M., Baetz, M., & Balbuena, L. (2018) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2018.07.008 · Cited by 18 · see citing works
Baer, M. M., LaCroix, J. M., Browne, J. C., Hassen, H. O., Perera, K. U., Weaver, J. J., Soumoff, A. A., & Ghahramanlou‐Holloway, M. (2017) · Archives of Suicide Research · doi:10.1080/13811118.2017.1358225 · Cited by 19 · see citing works
Molecular Pathways, Neural Circuits and Emerging Therapies for Self-Injurious Behaviour
Zhang, K., Ibrahim, G. M., & Gouveia, F. V. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26051938 · Cited by 14 · see citing works
“These approaches are best implemented in a family-based setting, where caregivers are trained to identify triggers and implement consistent behavioural strategies that mitigate SIB [86,187,190].”
InfluentialBergen, C., & McCabe, R. (2021) · Social Science & Medicine (1967) · doi:10.1016/j.socscimed.2021.114082 · Cited by 14 · see citing works
Functions of nonsuicidal self-injurious behavior in Russian patients with suicidal ideation
Зинчук, М. С., Kustov, G., Popova, S. B., Mishin, I., Voinova, N., Gersamija, A., Yakovlev, A. A., & Guekht, A. B. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1270944 · Cited by 10 · see citing works
Enhanced reactive inhibition in adolescents with non‐suicidal self‐injury disorder
Mirabella, G., Mancini, C., Pacifici, S., Guerrini, D., & Terrinoni, A. (2023) · Developmental Medicine & Child Neurology · doi:10.1111/dmcn.15794 · Cited by 13 · see citing works
Morthorst, B., Olsen, M. H., Jakobsen, J., Lindschou, J., Gluud, C., Heinrichsen, M., Møhl, B., Rubæk, L., Ojala, O., Hellner, C., et al. (2022) · JCPP Advances · doi:10.1002/jcv2.12115 · Cited by 13 · see citing works
“There is a lack of large‐scale NSSI intervention trials (Turner et al., 2014).”
BackgroundColet, I. E., Casadó‐Marín, L., Orós‐Navas, L., & Torner, R. D. R. (2025) · Journal of Child and Adolescent Psychiatric Nursing · doi:10.1111/jcap.70039 · Cited by 11 · see citing works
“These findings are consistent with a systematic review by Turner et al. (2014), which highlights the efficacy of various structured therapies focused on emotional regulation and enhancing coping skills in reducing NSSI.”
Qin, Y., Chen, H.-Y., Liu, F., Zou, T.-X., Jin, K., Teng, Z.-W., Liu, J.-Y., Yuan, H., Yang, J., Huang, C., et al. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-03183-x · Cited by 12 · see citing works
Reichl, C., Rockstroh, F., Lerch, S., Fischer-Waldschmidt, G., Koenig, J., & Kaess, M. (2023) · Psychological Medicine · doi:10.1017/s0033291723001447 · Cited by 12 · see citing works
Nonsuicidal self-injury in adolescents: current developments to help inform assessment and treatment
Pluhar, E. I., Lois, R., & Burton, E. (2018) · Current opinion in pediatrics · doi:10.1097/mop.0000000000000655 · Cited by 12 · see citing works
Flaherty, H. B. (2017) · Child and Adolescent Social Work Journal · doi:10.1007/s10560-017-0505-5 · Cited by 12 · see citing works
“This review reflects the finding of other notable reviews (Ougrin et al., 2012, 2015; Turner et al., 2014; Brent et al., 2013; Kerr et al., 2010; Townsend et al., 2001) that conclude that at this time there very few published randomized control trial (RCT) of therapeutic interventions (TI) that…”
Steele, S. J., Hearon, B. A., Batejan, K. L., Gironde, S., & Björgvinsson, Þ. (2016) · Journal of Clinical Psychology · doi:10.1002/jclp.22342 · Cited by 11 · see citing works
Zhou, H., Tang, Y., Li-juan, S., Wang, S., Guo, J., Xiao, J., Yan, C., & Gong, J. (2025) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2025.10.042 · Cited by 9 · see citing works
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“Whilst some systematic reviews suggest preliminary support for talking therapies [19, 20], other reviews have highlighted a lack of promising interventions [21].”
The functions of binge eating scale (FBES): Development and preliminary psychometric validation.
O’Loghlen, E., Galligan, R., & Grant, S. (2023) · Appetite · doi:10.1016/j.appet.2023.106479 · Cited by 11 · see citing works
“, the use of evidence-based treatments such as dialectical behavioural therapy to treat binge eating as a form of self-punishment or non-suicidal self-injury (Turner et al., 2014), or modified substance use interventions (e.”
Hylén, U., McGlinchey, A. J., Orešič, M., Bejerot, S., Humble, M. B., Särndahl, E., Hyötyläinen, T., & Eklund, D. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.778325 · Cited by 13 · see citing works
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“Future studies should explore possible treatment approaches that can modulate opioid system function in patients with NSSI (Turner et al., 2014).”
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Correlates of disclosure of non-suicidal self-injury amongst Australian university students
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The relationship between alexithymia and self-harm: The mediating role of mindfulness
Norman, H., Marzano, L., Oskis, A., & Coulson, M. (2021) · Current Psychology · doi:10.1007/s12144-021-01553-6 · Cited by 12 · see citing works
“Whilst a systematic review indicated tentatively promising results for DBT in treating self-harm (Turner et al., 2014), little research has been conducted to identify the types of people engaging in self-harm for whom mindfulness training would be most beneficial.”
Identifying Suicide and Self-Harm Research Priorities in North West England
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Non-suicidal self-injury: clinical presentation, assessment and management
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“However, the most promising psychological approaches include dialectical behaviour therapy, emotion-regulation group therapy, manual-assisted cognitive therapy and dynamic deconstructive psychotherapy (Turner et al 2014).”
BackgroundInfluentialWeedage, D., Kool-Goudzwaard, N., Meijnckens, D., Vermeiren, R. R. J. M., & Boonmann, C. (2025) · BMC Psychiatry · doi:10.1186/s12888-025-06868-3 · Cited by 11 · see citing works
“Although there is no gold standard for the treatment of self-injury, several interventions have shown promise in reducing or stopping NSSI [12, 94].”
- Authors
- Turner, B. J., Austin, S. B., & Chapman, A. L.
- Affiliations
- Simon Fraser University (CA)
- Corresponding author
- Turner, Brianna J
- Venue
- The Canadian Journal of Psychiatry
- Publisher
- SAGE Publications
- Published
- 2014-11
- Volume
- 59
- Issue
- 11
- Pages
- 576-585
- ISSN
- 0706-7437 (ISSN-L)
- 1497-0015
- PMC
- PMC4244876
- OpenAlex
- W2226199416
- Cited by
- 259
- References
- 109
- Citations by year
- 2026: 17 · 2025: 30 · 2024: 31 · 2023: 36 · 2022: 23 · 2021: 37 · 2020: 19 · 2019: 13 · 2018: 15 · 2017: 15 · 2016: 17 · 2015: 3 · 2014: 1 · 2013: 1 · 2012: 1
- FWCI
- 1.81
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The Canadian Journal of Psychiatry (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- American Psychological Association
- Michael Smith Health Research BC
- Health Canada
- Canadian Institutes of Health Research
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Keywords
- non-suicidal self-injury, suicidal self-injury, psychological intervention, pharmacotherapy, dialectical behavior therapy, atypical antipsychotics, aripiprazole, naltrexone, selective serotonin reuptake inhibitors, cognitive behavioral therapy, treatment efficacy
- MeSH terms
- Adolescent, Adult, Borderline Personality Disorder, Combined Modality Therapy, Humans, Psychotherapy, Psychotherapy, Group, Psychotropic Drugs, Suicide, Attempted, Cognitive Behavioral Therapy, Randomized Controlled Trials as Topic, Self-Injurious Behavior, Outcome Assessment, Health Care, Young Adult, Theory of Mind
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