The Effect of Childhood Abuse on the Risk of Adult Obesity
Abstract
Background The purpose of this study was to assess the association between childhood abuse and adult obesity. Methods We performed a comprehensive meta-analysis, which included studies that reported odds ratio (OR) estimates with 95% confidence intervals (CI). Summary estimates of association were obtained using a random-effects model. Heterogeneity among studies was evaluated using Cochran Q and I2 statistics. Results A total of 22 cohort studies (3 prospective, 19 retrospective) were included in this meta-analysis. The pooled OR was 1.23 (95% CI, 1.16-1.31). All 4 subcategories of abuse were associated with adult obesity: physical abuse (OR, 1.26; 95% CI, 1.10-1.42), psychological abuse (OR, 1.20; 95% CI, 1.07-1.33), sexual abuse (OR, 1.22; 95% CI, 1.05-1.38), and neglect (OR, 1.22; 95% CI, 1.12-1.32). Moreover, dose-response analysis showed that severe abuse (OR, 1.38; 95% CI, 1.14-1.1.62) was significantly associated with adult obesity compared with light/moderate abuse (OR, 1.01; 95% CI, 0.84-1.18). Although slight publication bias was observed (Egger test P = .05), effect sizes remained statistically significant in sensitivity analyses. Conclusions This research demonstrated a remarkably consistent association between childhood abuse and adult obesity. Medical practitioners need to be aware of the important role of childhood abuse in the development of obesity.
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ELS/CT has been repeatedly found to be independently associated with obesity and increased visceral fat deposition.
“obesity and increased visceral fat deposition (286–288)”
From Developmental Trajectories of Early Life Stress and Trauma: A Narrative Review on Neurobiological Aspects Beyond Stress System Dysregulation (2019) · cites this paper as [288]
Some studies have suggested a dose-dependent relation in these associations.
“while some studies have suggested a dose-dependent relation in these associations (288, 296).”
From Developmental Trajectories of Early Life Stress and Trauma: A Narrative Review on Neurobiological Aspects Beyond Stress System Dysregulation (2019) · cites this paper as [288]
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- Authors
- Wang, Y., Wu, B., Yang, H., & Song, X.
- Affiliations
- Liaoning Cancer Hospital & Institute (CN)
- Shenyang Emergency Center Shenyang, Liaoning, China
- University of California, San Francisco (US)
- Peking University (CN)
- Corresponding author
- Wang, Yue
- Venue
- Annals of Clinical Psychiatry
- Publisher
- SAGE Publications
- Published
- 2015-08
- Volume
- 27
- Issue
- 3
- Pages
- 175-184
- ISSN
- 1040-1237 (ISSN-L)
- 1547-3325
- OpenAlex
- W1070913503
- Cited by
- 21
- References
- 65
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 1 · 2021: 4 · 2020: 1 · 2019: 3 · 2018: 4 · 2017: 2 · 2016: 3
- FWCI
- 3.73
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of Clinical Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- PubMed
- Topics
- Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Keywords
- childhood abuse, adult obesity, physical abuse, psychological violence, sexual abuse, child neglect, abuse severity, dose-response relationship, childhood trauma
- MeSH terms
- Psychological Trauma, Adult, Child, Child Abuse, Humans, Obesity, Psychopathology, Risk Factors, Confidence Intervals, Adult Survivors of Child Abuse
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