Cited by 220Meta-analysis and systematic reviewsPsychology Research and Bibliometricsscientometrics and bibliometrics research

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Conducting Meta-Analyses Based on p Values: Reservations and Recommendations for Applying p -Uniform and p -Curve

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van Aert, Robbie C. M., Wicherts, Jelte M., van Assen, Marcel A. L. M.·2016·Perspectives on Psychological Science

Abstract

Because of overwhelming evidence of publication bias in psychology, techniques to correct meta-analytic estimates for such bias are greatly needed. The methodology on which the p-uniform and p-curve methods are based has great promise for providing accurate meta-analytic estimates in the presence of publication bias. However, in this article, we show that in some situations, p-curve behaves erratically, whereas p-uniform may yield implausible estimates of negative effect size. Moreover, we show that (and explain why) p-curve and p-uniform result in overestimation of effect size under moderate-to-large heterogeneity and may yield unpredictable bias when researchers employ p-hacking. We offer hands-on recommendations on applying and interpreting results of meta-analyses in general and p-uniform and p-curve in particular. Both methods as well as traditional methods are applied to a meta-analysis on the effect of weight on judgments of importance. We offer guidance for applying p-uniform or p-curve using R and a user-friendly web application for applying p-uniform.

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Crossref · 10.1177/1745691616650874

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Figures

Fig. 1. Probability-probability (P-P) plot for a meta-analysis of 20 studies with large heterogeneity.
Fig. 1. Probability-probability (P-P) plot for a meta-analysis of 20 studies with large heterogeneity.CC BY · PubMed Central
Fig. 2. Values for Kolmogorov-Smirnov (KS) test statistics in implementation of p-curve and p-uniform for the example with three observed effect sizes and p values close to .05. D stat = test statistics of KS test.
Fig. 2. Values for Kolmogorov-Smirnov (KS) test statistics in implementation of p-curve and p-uniform for the example with three observed effect sizes and p values close to .05. D stat = test statistics of KS test.CC BY · PubMed Central
Fig. 3. Effect size estimates in p-uniform and fixed-effect meta-analysis in case of four types of p-hacking. FE = fixed-effect; DV = dependent variable.
Fig. 3. Effect size estimates in p-uniform and fixed-effect meta-analysis in case of four types of p-hacking. FE = fixed-effect; DV = dependent variable.CC BY · PubMed Central
Fig. A1. Computation of conditional p values for Effect 3 (q3) for three effect sizes: δ = 0; δ = 0.5 (true effect size); and δ = 0.748 (estimate of fixed-effect meta-analysis). Critical value on Cohen’s d scale is denoted by dcv and observed effect size is denoted by dobs.
Fig. A1. Computation of conditional p values for Effect 3 (q3) for three effect sizes: δ = 0; δ = 0.5 (true effect size); and δ = 0.748 (estimate of fixed-effect meta-analysis). Critical value on Cohen’s d scale is denoted by dcv and observed effect size is denoted by dobs.CC BY · PubMed Central
Fig. A2. Observed conditional p values (solid black lines) and conditional p values under uniformity (dashed gray lines) for the example with three observed effect sizes. The three panels refer to the conditional p values for the p-uniform hypothesis test of no effect (δ = 0), p-uniform effect size estimate (δ = 0.5), and effect size obtained by fixed-effect (FE) meta-analysis (δ = 0.748).
Fig. A2. Observed conditional p values (solid black lines) and conditional p values under uniformity (dashed gray lines) for the example with three observed effect sizes. The three panels refer to the conditional p values for the p-uniform hypothesis test of no effect (δ = 0), p-uniform effect size estimate (δ = 0.5), and effect size obtained by fixed-effect (FE) meta-analysis (δ = 0.748).CC BY · PubMed Central
Fig. A3. Conditional p values as a function of true effect size (x axis) for each of the three observed effect sizes in the example. Effect sizes zero (δ = 0), true effect size (δ = 0.5), and estimated by fixed-effect meta-analysis (δ = 0.748) are indicated by vertical lines.
Fig. A3. Conditional p values as a function of true effect size (x axis) for each of the three observed effect sizes in the example. Effect sizes zero (δ = 0), true effect size (δ = 0.5), and estimated by fixed-effect meta-analysis (δ = 0.748) are indicated by vertical lines.CC BY · PubMed Central

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Citations

Cites

Show all 54 references

Research works printed but not linked: 4

  1. American Psychological Association, 2010, Publication manual
  2. Augusteijn H. E. M. (2015). The effect of publication bias on the Q test and assessment of heterogeneity (Unpublished master’s thesis). Tilburg University, Tilburg, the Netherlands.
  3. Raudenbush S. W., 2009, The handbook of research synthesis and meta-analysis, 295
  4. van Aert R. C. M., 2016, Estimating effect size in meta-analysis in the presence of publication bias and questionable research practices

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Metadata

Authors
van Aert, R. C. M., Wicherts, J. M., & van Assen, M. A. L. M.
Affiliations
  • Tilburg University (NL)
  • Utrecht University (NL)
Corresponding author
van Aert, Robbie C. M.
Venue
Perspectives on Psychological Science
Published
2016-09
Volume
11
Issue
5
Pages
713-729
ISSN
  • 1745-6916 (ISSN-L)
  • 1745-6924
OpenAlex
W2526603989
Cited by
219
References
54
Citations by year
2026: 12 · 2025: 13 · 2024: 24 · 2023: 22 · 2022: 28 · 2021: 22 · 2020: 25 · 2019: 23 · 2018: 20 · 2017: 27 · 2016: 3
FWCI
22.73
Type
journal article
Language
en
Open access
Locations
  • Perspectives on Psychological Science (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • Research portal (Tilburg University) (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
  • Utrecht University Repository (Utrecht University) (submittedVersion, other-oa)
  • OSF Preprints (OSF Preprints) (submittedVersion)
Topics
  • Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Psychology Research and Bibliometrics
  • Social Sciences › Library and Information Sciences › scientometrics and bibliometrics research
Keywords
p-curve, publication bias, meta-analysis, effect size estimation, p-hacking, heterogeneity, effect size overestimation, R package, web application
MeSH terms
Data Interpretation, Statistical, Humans, Psychology, Software, Meta-Analysis as Topic, Models, Statistical, Publication Bias, Internet

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