The effectiveness of psychosocial and behavioral interventions for informal dementia caregivers: meta-analyses and meta-regressions

Jütten, Linda Helena; Mark, Ruth Elaine; Wicherts, Jelte Michiel; Sitskoorn, Margriet Maria

doi:10.3233/jad-180508

Cited by 36Dementia and Cognitive Impairment ResearchNursing care and researchFamily Caregiving in Mental Illness

The effectiveness of psychosocial and behavioral interventions for informal dementia caregivers: meta-analyses and meta-regressions

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Jütten, Linda Helena, Mark, Ruth Elaine, Wicherts, Jelte Michiel, Sitskoorn, Margriet Maria·2018·Journal of Alzheimer’s Disease

DOI 10.3233/jad-180508

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Abstract

Background: Many psychosocial and behavioral interventions have been developed for informal dementia caregivers. Because existing meta-analyses only focused on a limited number of interventions and outcomes, how effective these interventions are overall and which interventions components are associated with larger effects has yet to be explored. Objective: To provide a comprehensive meta-analysis of the effectiveness of psychosocial and behavioral interventions on burden, depression, anxiety, quality of life, stress, and sense of competence in informal dementia caregivers. In addition, we examined if interventions which utilized more sessions and/or were delivered personally (face-to-face) had larger effect sizes. In exploratory meta-regressions, we examined seven additional moderators. Methods: The protocol was registered with PROSPERO, number CRD42017062555. We systematically searched the literature to identify controlled trials assessing the effect of psychosocial and behavioral interventions on the six outcome measures, for informal dementia caregivers. We performed six random effects meta-analyses, to assess the pooled effect sizes of the interventions. In addition, we performed separate meta-regressions, for each outcome, for each moderator. Results: The sample consisted of 60 studies. For all outcomes except anxiety, the pooled effects were small and in favor of the intervention group. No moderator was found to systematically predict these effects. There were no indications for publication bias or selection bias based on significance. Conclusion: Overall, the interventions yield significant (small) effects, independent of intervention characteristics. Future research should explore options to enhance the effectiveness of interventions aimed at assisting informal caregivers.

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Underserved ethnic groups, such as the Māori group in New Zealand, First Nation groups in Australia, Black individuals in the US and UK, and Hispanic individuals in the US, have higher prevalence of potentially modifiable risk factors.
“Underserved ethnic groups, such as the Māori group in New Zealand, First Nation groups in Australia, Black individuals in the US and UK, and Hispanic individuals in the US, have higher prevalence of potentially modifiable risk factors.(38-45)”
From Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission (2024) · cites this paper as [45]
The Exploratory predictors section examines characteristics of interventions for informal dementia caregivers, not the prevalence of modifiable risk factors across ethnic groups. Searches for the named groups and for ethnic differences in modifiable dementia risk factors found no passage in our copy addressing the claim. Page numbers were not available in the indexed passages. (LLM, conf=0.77)
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Authors: Jütten, L. H., Mark, R. E., Wicherts, J. M., & Sitskoorn, M. M.
Affiliations: Tilburg University (NL)
Corresponding author: Jütten, Linda Helena
ORCID: Jütten, Linda Helena
Mark, Ruth Elaine
Wicherts, Jelte Michiel
Sitskoorn, Margriet Maria
Venue: Journal of Alzheimer’s Disease
Publisher: SAGE Publications
Published: 2018-09-18
Volume: 66
Issue: 1
Pages: 149-172
ISSN: 1387-2877 (ISSN-L)
1875-8908
DOI: 10.3233/jad-180508
OpenAlex: W2890394071
Cited by: 36
References: 95
Citations by year: 2026: 3 · 2025: 6 · 2024: 5 · 2023: 5 · 2022: 4 · 2021: 4 · 2020: 9
FWCI: 0.50
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)
Locations: Journal of Alzheimer s Disease (publishedVersion)
Research portal (Tilburg University) (publishedVersion, other-oa)
PubMed (publishedVersion)
Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
Funders: ZonMw (733050608)
Nederlandse Organisatie voor Wetenschappelijk Onderzoek
Alzheimer Nederland
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Health Sciences › Health Professions › Pharmacy › Nursing care and research
Social Sciences › Psychology › Clinical Psychology › Family Caregiving in Mental Illness
Keywords: dementia caregiving, informal caregivers
MeSH terms: Behavior Therapy, Dementia, Humans, Regression Analysis, Social Support, Treatment Outcome, Caregivers

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The effectiveness of psychosocial and behavioral interventions for informal dementia caregivers: meta-analyses and meta-regressions

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