The DOI matches its Crossref record; 58 of the 60 references it cites were found in a registry or an index.
Biomechanics of the Sensor-Tissue Interface—Effects of Motion, Pressure, and Design on Sensor Performance and Foreign Body Response—Part II: Examples and Application
Open accessAbstract
This article is the second part of a two-part review in which we explore the biomechanics of the sensor-tissue interface as an important aspect of continuous glucose sensor biocompatibility. Part I, featured in this issue of Journal of Diabetes Science and Technology, describes a theoretical framework of how biomechanical factors such as motion and pressure (typically micromotion and micropressure) affect tissue physiology around a sensor and in turn, impact sensor performance. Here in Part II, a literature review is presented that summarizes examples of motion or pressure affecting sensor performance. Data are presented that show how both acute and chronic forces can impact continuous glucose monitor signals. Also presented are potential strategies for countering the ill effects of motion and pressure on glucose sensors. Improved engineering and optimized chemical biocompatibility have advanced sensor design and function, but we believe that mechanical biocompatibility, a rarely considered factor, must also be optimized in order to achieve an accurate, long-term, implantable sensor.
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“Such behavior was attributed in part to blood occlusion due to pressures applied to tissue adjacent to the sensor.86–87”
From Biocompatible Materials for Continuous Glucose Monitoring Devices (2013) · cites this paper as [87]
Citations
Cites
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Huiskes, R., Weinans, H., & van Rietbergen, B. (1992) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-199201000-00014 · Cited by 1,227
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Neovascularization of synthetic membranes directed by membrane microarchitecture
Brauker, J. H., Carr‐Brendel, V. E., Martinson, L. A., Crudele, J., Johnston, W. D., & Johnson, R. C. (1995) · Journal of Biomedical Materials Research · doi:10.1002/jbm.820291208 · Cited by 517
Søballé, K., Hansen, E. S., Brockstedt-Rasmussen, H., Jørgensen, P. H., & Bünger, C. (1992) · Journal of Orthopaedic Research® · doi:10.1002/jor.1100100216 · Cited by 506
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Cited by
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Items 101–102 of 102
Friman, O., Wiqvist, S., Lind, M., Zetterqvist, P., Rooijackers, O., Oldner, A., & Mårtensson, J. (2026) · Diabetes Technology & Therapeutics · doi:10.1177/15209156261479816
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Metadata
- Authors
- Helton, K. L., Ratner, B. D., & Wisniewski, N. A.
- Affiliations
- University of Washington (US)
- Profusa (United States) (US)
- Corresponding author
- Wisniewski, Natalie A.
- ORCID
- Ratner, Buddy D.
- Venue
- Journal of Diabetes Science and Technology
- Publisher
- SAGE Publications
- Published
- 2011-05
- Volume
- 5
- Issue
- 3
- Pages
- 647-656
- ISSN
- 1932-2968 (ISSN-L)
- PMC
- PMC3192630
- OpenAlex
- W2092619316
- Cited by
- 102
- References
- 60
- Citations by year
- 2026: 5 · 2025: 1 · 2024: 1 · 2023: 7 · 2022: 7 · 2021: 8 · 2020: 7 · 2019: 8 · 2018: 7 · 2017: 11 · 2016: 10 · 2015: 8 · 2014: 8 · 2013: 8 · 2012: 4
- Type
- conference abstract
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Diabetes Science and Technology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Physical Sciences › Chemistry › Analytical Chemistry › Electrochemical sensors and biosensors
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Keywords
- continuous glucose monitoring, micromotion, foreign body reaction, implantable glucose sensor, sensor design
- MeSH terms
- Animals, Biocompatible Materials, Biomechanical Phenomena, Blood Glucose, Diabetes Mellitus, Dogs, Equipment Design, Glucose, Humans, Motion, Pressure, Self Care, Swine, Blood Glucose Self-Monitoring, Reproducibility of Results, Porosity, Rats
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