Perceived Stress in Multiple Sclerosis: The Potential Role of Mindfulness in Health and Well-Being
Open accessAbstract
Stressful life events are associated with worsening neurological symptoms and decreased quality of life in multiple sclerosis (MS). Mindful consciousness can alter the impact of stressful events and has potential to improve health outcomes in MS. This study evaluated the relationship between trait mindfulness and perceived stress, coping, and resilience in people with MS. Quality of life was assessed as a secondary outcome. One hundred nineteen people with confirmed MS completed the Five-Facet Mindfulness Questionnaire, Perceived Stress Scale, Brief Coping Orientation for Problem Experiences, Connor-Davidson Resilience Scale, and Medical Outcome Study Short Form–36. Greater trait mindfulness was significantly associated with decreased psychological stress, better coping skills, increased resilience, and higher quality of life. After investigators controlled for confounders, mindfulness accounted for 25% of the variation in perceived stress scores and 44% of the variation in resilience scores. Results support further investigation of mindfulness training to enhance psychological resilience and improve well-being for those living with MS.
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Trait mindfulness is significantly associated with decreased psychological stress, a more constructive coping profile, increased resilience and better QoL in MS.
“Senders et al. [25] found that trait mindfulness is significantly associated with decreased psychological stress, a more constructive coping profile, increased resilience and better QoL in MS.”
In multiple sclerosis, trait mindfulness is related to lower psychological stress, a more constructive coping profile, increased resilience and higher quality of life.
“Senders et al. (2014) confirmed that in MS, trait mindfulness is related to lower psychological stress, a more constructive coping profile, increased resilience and higher quality of life.”
From The effectiveness of a body-affective mindfulness intervention for multiple sclerosis patients with depressive symptoms: A randomized controlled clinical trial (2017) · cites this paper as Senders et al. (2014)
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- Authors
- Senders, A., Bourdette, D., Hanes, D., Yadav, V., & Shinto, L.
- Affiliations
- National University of Natural Medicine (US)
- Oregon Health & Science University (US)
- Corresponding author
- Senders, Angela
- Venue
- Journal of Evidence-Based Complementary & Alternative Medicine
- Publisher
- SAGE Publications
- Published
- 2014-02-20
- Volume
- 19
- Issue
- 2
- Pages
- 104-111
- ISSN
- 1076-1675 (ISSN-L)
- 2156-5872
- 2156-5899
- PMC
- PMC4009344
- OpenAlex
- W2008808802
- Cited by
- 101
- References
- 43
- Citations by year
- 2025: 4 · 2024: 5 · 2023: 7 · 2022: 7 · 2021: 11 · 2020: 10 · 2019: 33 · 2018: 5 · 2017: 7 · 2016: 5 · 2015: 4 · 2014: 3
- FWCI
- 7.48
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Evidence-Based Complementary & Alternative Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (UL1TR000128)
- Agency for Healthcare Research and Quality (5t32hs017582-05, T32HS017582)
- Oregon Clinical and Translational Research Institute
- National Center for Research Resources (UL1RR024140)
- National Center for Advancing Translational Sciences
- National Center for Complementary and Integrative Health (R25AT002878, T32AT002688, AT002688)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Health Sciences › Medicine › Pathology and Forensic Medicine › Multiple Sclerosis Research Studies
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Keywords
- multiple sclerosis, perceived stress, trait mindfulness, coping, resilience, quality of life, psychological well-being, life events, mindfulness training
- MeSH terms
- Adaptation, Psychological, Adult, Aged, Female, Humans, Male, Middle Aged, Multiple Sclerosis, Quality of Life, Stress, Psychological, Cohort Studies, Linear Models, Mindfulness
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