Mindfulness-based cognitive therapy in COPD: a cluster randomised controlled trial
Open accessAbstract
A considerable proportion of patients with chronic obstructive pulmonary disease (COPD) entering pulmonary rehabilitation (PR) report psychological distress, which is often accompanied by poor physical health status. Mindfulness-based cognitive therapy (MBCT) has been shown to improve psychological and physical outcomes in other chronic diseases. We therefore evaluated the efficacy of MBCT as an add-on to a standard PR programme in COPD. COPD patients eligible for PR were cluster randomised to receive either an 8-week, group-based MBCT programme as an add-on to an 8-week PR programme (n=39), or PR alone (n=45). The primary outcomes of psychological distress and physical health status impairment were measured with the Hospital Anxiety and Depression Scale (HADS) and the COPD Assessment Test (CAT) before randomisation (T1), mid- (T2) and post-intervention (T3), and at 3 (T4) and 6 (T5) months’ follow-up . A statistically significant time×arm effect was found for the HADS (Cohen's d =0.62, 95% CIs ( d )=0.18–1.06, p=0.010). The treatment effect on the CAT failed to reach statistical significance ( d =0.42, 95% CIs ( d )=−0.06–0.90, p=0.061). MBCT showed a statistically significant and durable effect on psychological distress, indicating that MBCT may be an efficacious add-on to standard PR programmes in COPD.
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Respiratory physiological exploration during self-induced cognitive trance
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Factores psicológicos asociados a la enfermedad pulmonar obstructiva crónica: una revisión narrativa
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Bridging the gap in knowledge between dyspnoea scientists and clinicians
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Mental Health in Chronic and End-Stage Lung Disease
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- Authors
- Farver-Vestergaard, I., O'Toole, M. S., O'Connor, M., Løkke, A., Bendstrup, E., Basdeo, S. A., Cox, D. J., Dunne, P. J., Ruggeri, K., Early, F., & Zachariae, R.
- Affiliations
- Aarhus University (DK)
- Aarhus University Hospital (DK)
- Trinity College Dublin (IE)
- University of Cambridge (GB)
- Addenbrooke's Hospital (GB)
- ORCID
- Venue
- European Respiratory Journal
- Publisher
- European Respiratory Society (ERS)
- Published
- 2018-01-31
- Volume
- 51
- Issue
- 2
- Pages
- 1702082
- ISSN
- 0903-1936 (ISSN-L)
- 1399-3003
- OpenAlex
- W2789971734
- Semantic Scholar
- 9a78af3e3855987657daf81742190237f611d4a7
- Cited by
- 86
- References
- 45
- Citations by year
- 2026: 8 · 2025: 6 · 2024: 13 · 2023: 6 · 2022: 13 · 2021: 10 · 2020: 13 · 2019: 9 · 2018: 8
- FWCI
- 7.53
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- European Respiratory Journal (publishedVersion)
- PubMed (publishedVersion)
- Funders
- The Health Research Foundation of Central Denmark Region
- Aase og Ejnar Danielsens Fond (10-001480)
- Fonden til Lægevidenskabens Fremme (15-89)
- The Danish Lung Association Research Foundation (162663)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Keywords
- mindfulness-based cognitive therapy, chronic obstructive pulmonary disease, pulmonary rehabilitation, psychological distress, anxiety, depression, physical health status, COPD Assessment Test
- MeSH terms
- Adaptation, Psychological, Aged, Denmark, Female, Humans, Male, Middle Aged, Psychiatric Status Rating Scales, Quality of Life, Surveys and Questionnaires, Severity of Illness Index, Cognitive Behavioral Therapy, Linear Models, Treatment Outcome, Pulmonary Disease, Chronic Obstructive, Mindfulness
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