An ecological quantification of the relationships between water, sanitation and infant, child, and maternal mortality.
Open accessAbstract
BACKGROUND: Water and sanitation access are known to be related to newborn, child, and maternal health. Our study attempts to quantify these relationships globally using country-level data: How much does improving access to water and sanitation influence infant, child, and maternal mortality? METHODS: Data for 193 countries were abstracted from global databases (World Bank, WHO, and UNICEF). Linear regression was used for the outcomes of under-five mortality rate and infant mortality rate (IMR). These results are presented as events per 1000 live births. Ordinal logistic regression was used to compute odds ratios for the outcome of maternal mortality ratio (MMR). RESULTS: Under-five mortality rate decreased by 1.17 (95%CI 1.08-1.26) deaths per 1000, p < 0.001, for every quartile increase in population water access after adjustments for confounders. There was a similar relationship between quartile increase of sanitation access and under-five mortality rate, with a decrease of 1.66 (95%CI 1.11-1.32) deaths per 1000, p < 0.001. Improved water access was also related to IMR, with the IMR decreasing by 1.14 (95%CI 1.05-1.23) deaths per 1000, p < 0.001, with increasing quartile of access to improved water source. The significance of this relationship was retained with quartile improvement in sanitation access, where the decrease in IMR was 1.66 (95%CI 1.11-1.32) deaths per 1000, p < 0.001. The estimated odds ratio that increased quartile of water access was significantly associated with increased quartile of MMR was 0.58 (95%CI 0.39-0.86), p = 0.008. The corresponding odds ratio for sanitation was 0.52 (95%CI 0.32-0.85), p = 0.009, both suggesting that better water and sanitation were associated with decreased MMR. CONCLUSIONS: Our analyses suggest that access to water and sanitation independently contribute to child and maternal mortality outcomes. If the world is to seriously address the Millennium Development Goals of reducing child and maternal mortality, then improved water and sanitation accesses are key strategies.
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Two global studies and one focused on sub-Saharan Africa found increased access to improved water and sanitation to be significantly associated with decreased maternal mortality.
“Two global studies (with data from 193 [284] and 144 [286] countries) and one focused on sub-Saharan Africa [287] found increased access to improved water and sanitation to be significantly associated with decreased maternal mortality.”
From Water, sanitation, and women’s empowerment: A systematic review and qualitative metasynthesis (2022) · cites this paper as [284]
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Cites
An Introduction to Categorical Data Analysis
Agresti, A. (2006) · Wiley series in probability and statistics · doi:10.1002/0470114754 · Cited by 6,699 · see citing works
Hogan, M. C., Foreman, K. J., Naghavi, M., Ahn, S. Y., Wang, M., Makela, S. M., Lopez, A. D., Lozano, R., & Murray, C. J. (2010) · The Lancet · doi:10.1016/s0140-6736(10)60518-1 · Cited by 2,194 · see citing works
An Introduction to Categorical Data Analysis
Musiol, G. (1997) · Computational Statistics & Data Analysis · doi:10.1016/s0167-9473(97)84760-3 · Cited by 1,981 · see citing works
Fewtrell, L., Kaufmann, R. B., Kay, D., Enanoria, W. T. A., Haller, L., & Colford, J. M. (2004) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(04)01253-8 · Cited by 1,688 · see citing works
Temperature and Mortality in 11 Cities of the Eastern United States
Curriero, F. C. (2002) · American Journal of Epidemiology · doi:10.1093/aje/155.1.80 · Cited by 1,352 · see citing works
Diarrhoea: why children are still dying and what can be done
Wardlaw, T., Salama, P., Brocklehurst, C., Chopra, M., & Mason, E. M. (2009) · The Lancet · doi:10.1016/s0140-6736(09)61798-0 · Cited by 1,097 · see citing works
Victora, C. G., Fontaine, O., Morris, S., Schellenburg, J., Gray, R., Black, R., Borros, A., Ashraf, R., Morris, J., Fucks, S., et al. (2000) · The Lancet · doi:10.1016/s0140-6736(00)82011-5 · Cited by 1,058 · see citing works
Groundwater Arsenic Contamination in Bangladesh and West Bengal, India
Chowdhury, U. K., Biswas, B. K., Chowdhury, T. R., Samanta, G., Mandal, B. K., BASU, G. C., Chanda, C. R., Lodh, D., Saha, K. C., Mukherjee, S. K., et al. (2000) · Environmental Health Perspectives · doi:10.1289/ehp.00108393 · Cited by 900 · see citing works
Estimating the Burden of Disease from Water, Sanitation, and Hygiene at a Global Level
Prüss, A., Kay, D., Fewtrell, L., & Bartram, J. (2002) · Environmental Health Perspectives · doi:10.1289/ehp.110-1240845 · Cited by 833 · see citing works
Spatial epidemiology: methods and applications
Elliott, P., Wakefield, J. C., Best, N. G., & Briggs, D. (2001) · doi:10.1093/acprof:oso/9780198515326.003.0001 · Cited by 765 · see citing works
Estimating child mortality due to diarrhoea in developing countries.
Boschi-Pinto, C., Velebit, L., & Shibuya, K. (2008) · Bulletin of the World Health Organization · doi:10.2471/blt.07.050054 · Cited by 727 · see citing works
Royston, P. (2009) · The Stata Journal: Promoting communications on statistics and Stata · doi:10.1177/1536867x0900900308 · Cited by 428 · see citing works
Knowns and unknowns on burden of disease due to chemicals: a systematic review
Prüss-Ustün, A., Vickers, C., Haefliger, P., & Bertollini, R. (2011) · Environmental Health · doi:10.1186/1476-069x-10-9 · Cited by 397 · see citing works
Maternal Mortality for 181 Countries, 1980−2008
Hogan, M. C., Foreman, K. J., Naghavi, M., Ahn, S. Y., Wang, M., Makela, S. M., López, A. D., Lozano, R., & Murray, C. J. L. (2011) · Obstetric Anesthesia Digest · doi:10.1097/01.aoa.0000397097.96320.28 · Cited by 387 · see citing works
Spatial Epidemiology: Methods and Applications
Orford, S. (2001) · International Journal of Epidemiology · doi:10.1093/ije/30.5.1204 · Cited by 343 · see citing works
Estimates of Global Prevalence of Childhood Underweight in 1990 and 2015
de Onís, M. (2004) · JAMA · doi:10.1001/jama.291.21.2600 · Cited by 290 · see citing works
The Effect of the 1995 Heat Wave in Chicago on All-Cause and Cause-Specific Mortality
Kaiser, R., Tertre, A. L., Schwartz, J. D., Gotway, C. A., Daley, W. R., & Rubin, C. (2007) · American Journal of Public Health · doi:10.2105/ajph.2006.100081 · Cited by 228 · see citing works
Reducing maternal mortality in the developing world: sector-wide approaches may be the key
Goodburn, E., & Campbell, O. (2001) · BMJ · doi:10.1136/bmj.322.7291.917 · Cited by 134 · see citing works
Cancer Mortality in U.S. Counties with Hazardous Waste Sites and Ground Water Pollution
Griffith, J., DUNCAN, R. C., Riggan, W. B., et al. (1989) · Archives of Environmental Health An International Journal · doi:10.1080/00039896.1989.9934378 · Cited by 134 · see citing works
Maternal and birth attendant hand washing and neonatal mortality in southern Nepal
Rhee, V., Mullany, L. C., Khatry, S. K., Katz, J., LeClerq, S. C., Darmstadt, G. L., & Tielsch, J. M. (2008) · Archives of Pediatrics & Adolescent Medicine · doi:10.1001/archpedi.162.7.603 · Cited by 102 · see citing works
Ecological correlation studies
Richardson, S. T., & Monfort, C. (2001) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780198515326.003.0011 · Cited by 81 · see citing works
Jerrett, M., Eyles, J. D., Cole, D. C., et al. (1997) · Environment and Planning A Economy and Space · doi:10.1068/a291777 · Cited by 74 · see citing works
Environmental health and child survival: epidemiology, economics, experiences
Bank, W. (2009) · Choice Reviews Online · doi:10.5860/choice.46-2691 · Cited by 53 · see citing works
The Ecologic Method in the Study of Environmental Health. I. Overview of the Method
Walter, S. D. (1991) · Environmental Health Perspectives · doi:10.2307/3431294 · Cited by 52 · see citing works
Assessing spatial patterns in disease rates
Walter, S. D. (1993) · Statistics in Medicine · doi:10.1002/sim.4780121914 · Cited by 50 · see citing works
The geographic variation of cancer incidence in Ontario.
Walter, S. D., Birnie, S. E., Marrett, L. D., et al. (1994) · American Journal of Public Health · doi:10.2105/ajph.84.3.367 · Cited by 47 · see citing works
Environmental Health and Child Survival
Bank, W. (2008) · World Bank, Washington, DC eBooks · doi:10.1596/978-0-8213-7236-4 · Cited by 19 · see citing works
Petitti, D. B. (1999) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780195133646.003.02 · Cited by 16 · see citing works
Utenriksdepartement, N. K., Gender, & Water Alliance (2006) · Medical Entomology and Zoology · Cited by 3 · see citing works
(2008) · World Health Organization eBooks
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Sahoo, K. C., Hulland, K. R. S., Caruso, B. A., Swain, R., Freeman, M. C., Panigrahi, P., & Dreibelbis, R. (2015) · Social Science & Medicine · doi:10.1016/j.socscimed.2015.06.031 · Cited by 300 · see citing works
Mapping 123 million neonatal, infant and child deaths between 2000 and 2017
Burstein, R., Henry, N. J., Collison, M. L., Marczak, L. B., Sligar, A., Watson, S., Marquez, N., Abbasalizad-Farhangi, M., Abbasi, M., Abd-Allah, F., et al. (2019) · Nature · doi:10.1038/s41586-019-1545-0 · Cited by 276 · see citing works
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Allen, P., Pilar, M., Walsh-Bailey, C., Hooley, C., Mazzucca, S., Lewis, C. C., Mettert, K. D., Dorsey, C. N., Purtle, J., Kepper, M. M., et al. (2020) · Implementation Science · doi:10.1186/s13012-020-01007-w · Cited by 164 · see citing works
Collins, S. M., Mbullo Owuor, P., Miller, J. D., Boateng, G. O., Wekesa, P., Onono, M., & Young, S. L. (2019) · Global Public Health · doi:10.1080/17441692.2018.1521861 · Cited by 170 · see citing works
Caruso, B. A., Clasen, T. F., Hadley, C., Yount, K. M., Haardörfer, R., Rout, M., Dasmohapatra, M., & Cooper, H. L. (2017) · BMJ Global Health · doi:10.1136/bmjgh-2017-000414 · Cited by 165 · see citing works
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Corburn, J., & Hildebrand, C. (2015) · Journal of Environmental and Public Health · doi:10.1155/2015/209505 · Cited by 149 · see citing works
Corburn, J., & Karanja, I. (2016) · Health Promotion International · doi:10.1093/heapro/dau100 · Cited by 93 · see citing works
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Caruso, B. A., Conrad, A., Patrick, M., Owens, A., Kviten, K., Zarella, O., Rogers, H., & Sinharoy, S. S. (2022) · PLOS Water · doi:10.1371/journal.pwat.0000026 · Cited by 94 · see citing works
Nelson Ekane, N. E., Björn Nykvist, B. N., Marianne Kjellén, M. K., Stacey Noel, S. N., & Nina Weitz, N. W. (2014) · Waterlines · doi:10.3362/1756-3488.2014.024 · Cited by 37 · see citing works
Acheampong, M., Ejiofor, C., & Salinas-Miranda, A. (2017) · Maternal and Child Health Journal · doi:10.1007/s10995-017-2260-9 · Cited by 22 · see citing works
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You, J., Staddon, C., Cook, A., Walker, J., Boulton, J., Powell, W., & Ieropoulos, I. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17072175 · Cited by 20 · see citing works
Klugman, J., Li, L., Barker, K. M., Parsons, J., & Dale, K. (2019) · SSM - Population Health · doi:10.1016/j.ssmph.2019.100486 · Cited by 16 · see citing works
Mariwah, S. (2018) · GeoJournal · doi:10.1007/s10708-016-9765-4 · Cited by 11 · see citing works
- Authors
- Cheng, J. J., Schuster-Wallace, C. J., Watt, S., Newbold, B. K., & Mente, A.
- Affiliations
- McMaster University (CA)
- United Nations University Institute for Water, Environment, and Health (CA)
- Hamilton General Hospital (CA)
- Corresponding author
- Cheng, June J
- Venue
- Environmental Health
- Published
- 2012-01-27
- Volume
- 11
- Issue
- 1
- Pages
- 4-4
- ISSN
- 1476-069X (ISSN-L)
- PMC
- PMC3293047
- OpenAlex
- W2169242337
- Cited by
- 168
- References
- 31
- Citations by year
- 2026: 6 · 2025: 8 · 2024: 12 · 2023: 14 · 2022: 12 · 2021: 10 · 2020: 12 · 2019: 13 · 2018: 11 · 2017: 17 · 2016: 12 · 2015: 13 · 2014: 19 · 2013: 8 · 2012: 1
- FWCI
- 12.21
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Environmental Health (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- HARVEST (University of Saskatchewan) (submittedVersion, cc-by)
- UNU Collections (United Nations University) (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- Hamilton Health Sciences
- McMaster University
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Child Nutrition and Water Access
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Global Maternal and Child Health
- Physical Sciences › Environmental Science › Water Science and Technology › Water Resource Management and Quality
- Keywords
- water access, sanitation access, infant mortality, child mortality, maternal mortality, under-five mortality, Millennium Development Goals, global health, country-level data, Millennium Development Goal 7, Millennium Development Goal 5
- MeSH terms
- Child, Preschool, Developing Countries, Female, Humans, Infant, Infant Mortality, Infant, Newborn, Maternal Mortality, Sanitation, Water Supply, Linear Models, Logistic Models, Odds Ratio, Developed Countries, Child Mortality
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