The effects of time-released garlic powder tablets on multifunctional cardiovascular risk in patients with coronary artery disease
Open accessAbstract
The double-blinded placebo-controlled randomized study has been performed in 51 coronary heart disease (CHD) patients to estimate the effects of time-released garlic powder tablets Allicor on the values of 10-year prognostic risk of acute myocardial infarction (fatal and non-fatal) and sudden death, with the respect of secondary CHD prevention. It has been demonstrated that 12-month treatment with Allicor results in the significant decrease of cardiovascular risk by 1.5-fold in men (p < 0.05), and by 1.3-fold in women. The above results were equitable also in terms of relative risks. The main effect that played a role in cardiovascular risk reduction was the decrease in LDL cholesterol by 32.9 mg/dl in men (p < 0.05), and by 27.3 mg/dl in women. Thus, the most significant effects were observed in men, while in women the decrease of cardiovascular risk appeared as a trend that might be due presumably to the insufficient sample size. Since Allicor is the remedy of natural origin, it is safe with the respect to adverse effects and allows even perpetual administration that may be crucial for the secondary prevention of atherosclerotic diseases in CHD patients.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Garlic administration at a dose of 300 and 60 mg/day for 12 months and 12 weeks, respectively, decreased total cholesterol, triglyceride, and LDL while increased HDL in patients.
“Sobenin et al. [110,111] revealed that garlic administration at a dose of 300 and 60 mg/day for 12 months and 12 weeks, respectively decreased TC, TG, and LDL while increased HDL.”
From Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review (2020) · cites this paper as [111]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group (2002) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.288.23.2981 · Cited by 5,664 · see citing works
Assmann, G., Cullen, P., & Schulte, H. (2002) · Circulation · doi:10.1161/hc0302.102575 · Cited by 1,541 · see citing works
Tunstall-Pedoe, H., Kuulasmaa, K., Mähönen, M., Tolonen, H., & Ruokokoski, E. (1999) · The Lancet · doi:10.1016/s0140-6736(99)04021-0 · Cited by 1,444 · see citing works
Intake of Garlic and Its Bioactive Components
Amagase, H., Petesch, B. L., Matsuura, H., Kasuga, S., & Itakura, Y. (2001) · Journal of Nutrition · doi:10.1093/jn/131.3.955s · Cited by 1,052 · see citing works
The Chemistry of Garlic and Onions
Block, E. (1985) · Scientific American · doi:10.1038/scientificamerican0385-114 · Cited by 936 · see citing works
A placebo-controlled study of the effect of sour milk on blood pressure in hypertensive subjects
Hata, Y., Yamamoto, M., Ohni, M., Nakajima, K., Nakamura, Y., & Takano, T. (1996) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/64.5.767 · Cited by 509 · see citing works
Kannel, W. B., Neaton, J. D., Wentworth, D. N., Thomas, H. E., Stamler, J., Hulley, S. B., & Kjelsberg, M. O. (1986) · American Heart Journal · doi:10.1016/0002-8703(86)90481-3 · Cited by 502 · see citing works
Cholesterol-Lowering Effect of Garlic Extracts and Organosulfur Compounds: Human and Animal Studies
Yeh, Y.-Y., & Liu, L. (2001) · Journal of Nutrition · doi:10.1093/jn/131.3.989s · Cited by 425 · see citing works
A meta-analysis of the effect of garlic on blood pressure
Silagy, C., & Neil, H. A. W. (1994) · Journal of Hypertension · doi:10.1097/00004872-199404000-00017 · Cited by 340 · see citing works
Garlic Shows Promise for Improving Some Cardiovascular Risk Factors
Ackermann, R. T., Mulrow, C. D., Ramirez, G., Gardner, C. D., Morbidoni, L., & Lawrence, V. A. (2001) · Archives of Internal Medicine · doi:10.1001/archinte.161.6.813 · Cited by 295 · see citing works
Garlic as a Lipid Lowering Agent—A Meta-Analysis
Silagy, C., & Neil, A. (1994) · Journal of the Royal College of Physicians of London · doi:10.1016/s0035-8819(25)00866-9 · Cited by 261 · see citing works
Stamler, J., Dyer, A. R., Shekelle, R. B., Neaton, J. D., & Stamler, R. (2008) · Cardiology · doi:10.1159/000175868 · Cited by 250 · see citing works
Bordia, A., Verma, S. K., & Srivastava, K. C. (1998) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/s0952-3278(98)90034-5 · Cited by 249 · see citing works
Multiple Risk Factor Intervention Trial
Eberly, L. E., Stamler, J., Kuller, L. H., & Neaton, J. D. (2014) · doi:10.1002/9781118596005.ch47 · Cited by 206 · see citing works
Garlic reduces plasma lipids by inhibiting hepatic cholesterol and triacylglycerol synthesis
Yeh, Y., & Yeh, S. (1994) · Lipids · doi:10.1007/bf02536728 · Cited by 193 · see citing works
Quantitative Determination of Allicin and Alliin from Garlic by HPLC*
Iberl, B., Winkler, G., Müller, B., & Knobloch, K. (1990) · Planta Medica · doi:10.1055/s-2006-960969 · Cited by 164 · see citing works
Effect of garlic on blood lipids in patients with coronary heart disease
Bordia, A. (1981) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/34.10.2100 · Cited by 163 · see citing works
Garlic and Garlic-Derived Compounds Inhibit Human Squalene Monooxygenase
Gupta, N. J., & Porter, T. D. (2001) · Journal of Nutrition · doi:10.1093/jn/131.6.1662 · Cited by 157 · see citing works
Voss, R., Cullen, P., Schulte, H., & Assmann, G. (2002) · International Journal of Epidemiology · doi:10.1093/ije/31.6.1253 · Cited by 157 · see citing works
Multiple inhibitory effects of garlic extracts on cholesterol biosynthesis in hepatocytes
Gebhardt, R. (1993) · Lipids · doi:10.1007/bf02536055 · Cited by 153 · see citing works
Hypertension and hyperlipidaemia: garlic helps in mild cases.
Auer, W., Eiber, A., Hertkorn, E., Hoehfeld, E., Koehrle, U., Lorenz, A., Mader, F. M., Merx, W., Otto, G., & Schmid-Otto, B. (1990) · PubMed · Cited by 101 · see citing works
Garlic: Empiricism or Science?
Aviello, G., Abenavoli, L., Borrelli, F., Capasso, R., Izzo, A. A., Lembo, F., Romano, B., & Capasso, F. (2009) · Natural Product Communications · doi:10.1177/1934578x0900401231 · Cited by 82 · see citing works
Liu, L., & Yeh, Y. (2001) · Lipids · doi:10.1007/s11745-001-0734-4 · Cited by 72 · see citing works
Cardiovascular effects of garlic (Allium sativum): a review.
Ernst, E. K. (1987) · PubMed · Cited by 65 · see citing works
Bordia, A., Verma, S. K., & Srivastava, K. C. (1996) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/s0952-3278(96)90099-x · Cited by 62 · see citing works
Direct Anti-atherosclerosis-related Effects of Garlic
Orekhov, A. N., Tertov, V. V., Sobenin, I. A., & Pivovarova, E. M. (1995) · Annals of Medicine · doi:10.3109/07853899509031938 · Cited by 60 · see citing works
Self-citationGarlic preparations for prevention of atherosclerosis
Berthold, H. K., & Sudhop, T. (1998) · Current Opinion in Lipidology · doi:10.1097/00041433-199812000-00008 · Cited by 43 · see citing works
Blood lipids and coronary heart disease
Gotto, A. M., Assmann, G., Carmena, R., Davignon, J., Fernandex-Cruz, A., Fruchart, J., Kastelein, J. J. P., & Paoletti, R. (2000) · Cited by 15 · see citing works
Pocket guide to prevention of coronary heart disease
Carmena, R., Fruchart, J., OLSSON, A. G., Paoletti, R., Riesen, W., & Tikkanen, M. J. (2003) · Cited by 15 · see citing works
On the Quantitative Determination of Allicin and Alliin from Garlic by HPLC
Iberl, B., Winkler, G., Müller, B., Jansen, H., & Knobloch, K. (1989) · Planta Medica · doi:10.1055/s-2006-962217 · Cited by 14 · see citing works
Andrianova, I. V., Fomchenkov, I. V., & Orekhov, A. N. (2002) · PubMed · Cited by 10 · see citing works
Self-citationAndrianova, I. V., Ионова, В. Г., Demina, E. G., Shabalina, A. A., Karabasova, I. A., Li, L., Te, P., & Orekhov, A. N. (2001) · PubMed · Cited by 5 · see citing works
Self-citationEffect of allicor on platelet aggregationin vitro andex vivo
Andrianova, I. V., Ахнафович, Г. З., Ionova, V. G., & Orekhov, A. N. (1997) · Bulletin of Experimental Biology and Medicine · doi:10.1007/bf02445068 · Cited by 1 · see citing works
Self-citation[Effect of the garlic tablets allicor on thrombocyte aggregation in vitro and ex vivo].
Andrianova, I. V., Ахнафович, Г. З., Ionova, V. G., & Orekhov, A. N. (1997) · PubMed · Cited by 1 · see citing works
Self-citation
Flagged first, then by citations
Research works printed but not linked: 3
- Ackermann RT Garlic shows promise for improving some cardiovascular risk factors Arch Intern Med 2001 161 813 24 10.1001/archinte.161.6.813 11268223 · DOI · Paper page
- Assmann G Cullen P Schulte H Simple scoring scheme for calculating the risk of acute coronary events based on the 10-year follow-up of the prospective cardiovascular Muenster (PROCAM) study Circulation 2002 105 310 5 10.1161/hc0302.102575 11804985 · DOI · Paper page
- Yeh YY Liu L Cholesterol-lowering effect of garlic extracts and organosulfur compounds: human and animal studies J Nutr 2001 131 989S 93S 11238803
Cited by
Sorted by citations
Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review
El-Saber Batiha, G., Magdy Beshbishy, A., G. Wasef, L., Elewa, Y. H. A., A. Al-Sagan, A., Abd El-Hack, M. E., Taha, A. E., M. Abd-Elhakim, Y., & Prasad Devkota, H. (2020) · Nutrients · doi:10.3390/nu12030872 · Cited by 931 · see citing works
The Health Potential of Fruits and Vegetables Phytochemicals: Notable Examples
Rodríguez‐Casado, A. (2014) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2012.755149 · Cited by 267 · see citing works
Allicin and health: A comprehensive review
Salehi, B., Zucca, P., Orhan, İ. E., Azzini, E., Adetunji, C. O., Mohammed, S. A., Banerjee, S., Sharopov, F. S., Rigano, D., Sharifi‐Rad, J., et al. (2019) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2019.03.003 · Cited by 249 · see citing works
Potential Health Benefit of Garlic Based on Human Intervention Studies: A Brief Overview
Ansary, J., Forbes-Hernández, T. Y., Gil, E., Cianciosi, D., Zhang, J., Elexpuru-Zabaleta, M., Simal-Gandara, J., Giampieri, F., & Battino, M. (2020) · Antioxidants · doi:10.3390/antiox9070619 · Cited by 217 · see citing works
Andreadou, I., Iliodromitis, E. K., Rassaf, T., Schulz, R., Papapetropoulos, A., & Ferdinandy, P. (2014) · British Journal of Pharmacology · doi:10.1111/bph.12811 · Cited by 213 · see citing works
Effect of garlic on serum lipids: an updated meta-analysis
Ried, K., Toben, C., & Fakler, P. (2013) · Nutrition Reviews · doi:10.1111/nure.12012 · Cited by 203 · see citing works
A review on the effects of Allium sativum (Garlic) in metabolic syndrome
Hosseini, A., & Hosseinzadeh, H. (2015) · Journal of Endocrinological Investigation · doi:10.1007/s40618-015-0313-8 · Cited by 169 · see citing works
Potential therapeutic effects of functionally active compounds isolated from garlic
Yun, H., Ban, J. O., Park, K., Lee, C. K., Jeong, H., Han, S., & Hong, J. T. (2013) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2013.12.005 · Cited by 144 · see citing works
Functional Food and Cardiovascular Disease Prevention and Treatment: A Review
Asgary, S., Rastqar, A., & Keshvari, M. (2018) · Journal of the American College of Nutrition · doi:10.1080/07315724.2017.1410867 · Cited by 132 · see citing works
Garlic-Derived Organic Polysulfides and Myocardial Protection
Bradley, J., Organ, C. L., & Lefer, D. J. (2016) · Journal of Nutrition · doi:10.3945/jn.114.208066 · Cited by 122 · see citing works
Garlic: Health benefits and actions
Tsai, C.-W., Chen, H., Sheen, L.-Y., & Lii, C. (2012) · Biomedicine · doi:10.1016/j.biomed.2011.12.002 · Cited by 121 · see citing works
Ray, B., B. Chauhan, N., & K. Lahiri, D. (2011) · Current Medicinal Chemistry · doi:10.2174/092986711796504664 · Cited by 100 · see citing works
Anti-hyperlipidemia of garlic by reducing the level of total cholesterol and low-density lipoprotein
Sun, Y.-E., Wang, W., & Qin, J. (2018) · Medicine · doi:10.1097/md.0000000000010255 · Cited by 94 · see citing works
AGING OF THE SUBVENTRICULAR ZONE NEURAL STEM CELL NICHE.
Conover, J. C., & Shook, B. A. (2011) · Europe PMC (PubMed Central) · Cited by 92 · see citing works
Chemical constituents and medicinal properties of Allium species
Bastaki, S. M. A., Ojha, S. K., Kalász, H., & Adeghate, E. A. (2021) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-021-04213-2 · Cited by 96 · see citing works
Role of garlic usage in cardiovascular disease prevention: An evidence-based approach
Qidwai, W., & Ashfaq, T. (2013) · Evidence-Based Complementary and Alternative Medicine · doi:10.1155/2013/125649 · Cited by 83 · see citing works
Panyod, S., Wu, W., Chen, P.-C., Chong, K.-V., Yang, Y.-T., Chuang, H.-L., Chen, C., Chen, R.-A., Liu, P., Chung, C., et al. (2022) · npj Biofilms and Microbiomes · doi:10.1038/s41522-022-00266-3 · Cited by 85 · see citing works
Self-citationSharifi‐Rad, J., Quispe, C., Shaheen, S., Haouari, M. E., Azzini, E., Butnariu, M., Sărac, I., Pentea, M., Ramírez‐Alarcón, K., Martorell, M., et al. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1924612 · Cited by 76 · see citing works
Zeng, T., Guo, F., Zhang, C., Song, F., Zhao, X., & Xie, K. (2012) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.5557 · Cited by 73 · see citing works
Kwak, J. S., Kim, J. Y., Paek, J. E., Lee, Y. J., Kim, H.-R., Park, D.-S., & Kwon, O. (2014) · Nutrition Research and Practice · doi:10.4162/nrp.2014.8.6.644 · Cited by 72 · see citing works
Therapeutic effects of garlic in cardiovascular atherosclerotic disease
Sobenin, I. A., Myasoedova, V. A., Iltchuk, M., Zhang, D., & Orekhov, A. N. (2019) · Chinese Journal of Natural Medicines · doi:10.1016/s1875-5364(19)30088-3 · Cited by 70 · see citing works
Self-citationZhou, L., Guo, X., Bi, J., Yi, J., Chen, Q., Wu, X., & Zhou, M. (2016) · Journal of Food Processing and Preservation · doi:10.1111/jfpp.12734 · Cited by 67 · see citing works
Garlic: A systematic review of the effects on cardiovascular diseases
Imaizumi, V. M., Laurindo, L. F., Manzan, B., Guiguer, É. L., Oshiiwa, M., Otoboni, A. M. M. B., Araújo, A. C., Tofano, R. J., & Barbalho, S. M. (2022) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2022.2043821 · Cited by 65 · see citing works
Anti-atherosclerotic plants which modulate the phenotype of vascular smooth muscle cells
Shehabi, T. S. A., Iratni, R., & Eid, A. H. (2015) · Phytomedicine · doi:10.1016/j.phymed.2015.10.016 · Cited by 63 · see citing works
Ribeiro, M. M., Alvarenga, L., Cardozo, L., Chermut, T. R., Sequeira, J., Moreira, L. D. S. G., Teixeira, K. T. R., Shiels, P. G., Stenvinkel, P., & Mafra, D. (2021) · Clinical Nutrition · doi:10.1016/j.clnu.2021.03.005 · Cited by 62 · see citing works
Mollazadeh, H., Mahdian, D., & Hosseinzadeh, H. (2018) · Phytomedicine · doi:10.1016/j.phymed.2018.09.024 · Cited by 62 · see citing works
Kim, M.-J., Yoo, Y. C., Kim, H. J., Shin, S. K., Sohn, E. J., Min, A. Y., Sung, N. Y., & Kim, M. R. (2014) · Journal of Medicinal Food · doi:10.1089/jmf.2013.3043 · Cited by 54 · see citing works
Szulińska, M., Kręgielska-Narożna, M., Świątek, J., Styś, P., Kuźnar-Kamińska, B., Jakubowski, H., Walkowiak, J., & Bogdański, P. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.03.131 · Cited by 53 · see citing works
Orekhov, A. N., & Ivanova, E. A. (2016) · Phytomedicine · doi:10.1016/j.phymed.2016.01.003 · Cited by 43 · see citing works
Self-citationSoleimani, D., Paknahad, Z., Askari, G., Iraj, B., & Feizi, A. (2016) · Advanced Biomedical Research · doi:10.4103/2277-9175.174962 · Cited by 43 · see citing works
He, H., Ma, Y., Huang, H., Huang, C., Chen, Z., Chen, D., Gu, Y., Wang, X., & Chen, J. (2020) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2020.173803 · Cited by 43 · see citing works
Nwokocha, C. R., Ozolua, R. I., Owu, D. U., Nwokocha, M., & Ugwu, A. C. (2011) · PubMed · Cited by 40 · see citing works
A Systematic Review and Meta-Analysis of Ayurvedic Herbal Preparations for Hypercholesterolemia
Gyawali, D., Vohra, R., Orme‐Johnson, D. W., Ramaratnam, S., & Schneider, R. H. (2021) · Medicina · doi:10.3390/medicina57060546 · Cited by 40 · see citing works
Roles and mechanisms of garlic and its extracts on atherosclerosis: A review
Li, M., Yun, W., Wang, G., Li, A., Gao, J., & He, Q. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.954938 · Cited by 37 · see citing works
Garlic (Allium sativum L.) in the management of hypertension and dyslipidemia – A systematic review
Chan, W.-J. J., McLachlan, A. J., Luca, E., & Harnett, J. (2019) · Journal of Herbal Medicine · doi:10.1016/j.hermed.2019.100292 · Cited by 36 · see citing works
Detection of Volatile Metabolites Derived from Garlic (Allium sativum) in Human Urine
Scheffler, L., Sauermann, Y., Heinlein, A., Sharapa, C., & Buettner, A. (2016) · Metabolites · doi:10.3390/metabo6040043 · Cited by 34 · see citing works
Advancing functional food regulation
Martirosyan, D. M., & Stratton, S. (2023) · Bioactive Compounds in Health and Disease · doi:10.31989/bchd.v6i7.1178 · Cited by 31 · see citing works
Self-citationModulation of gut microbiota by foods and herbs to prevent cardiovascular diseases
Panyod, S., Wu, W.-K., Chen, C., Wu, M., Ho, C., & Sheen, L. (2021) · Journal of Traditional and Complementary Medicine · doi:10.1016/j.jtcme.2021.09.006 · Cited by 32 · see citing works
Sahidur, M. R., Islam, S., & Jahurul, M. H. A. (2023) · Food Chemistry Advances · doi:10.1016/j.focha.2023.100353 · Cited by 30 · see citing works
Development of Antiatherosclerotic Drugs on the basis of Natural Products Using Cell Model Approach
Orekhov, A. N., Sobenin, I. A., Ревин, В. В., & Bobryshev, Y. V. (2015) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2015/463797 · Cited by 27 · see citing works
Self-citationFinnbjörnsdóttir, R. G., Carlsen, H. K., Þorsteinsson, Þ., Oudin, A., Lund, S. H., Gíslason, Þ., & Rafnsson, V. (2016) · PLoS ONE · doi:10.1371/journal.pone.0154946 · Cited by 27 · see citing works
Traditional plants with antioxidant properties in clinical trials—A systematic review
Marmitt, D. J., Bitencourt, S., da Silva, G. R., Rempel, C., & Goettert, M. I. (2021) · Phytotherapy Research · doi:10.1002/ptr.7202 · Cited by 26 · see citing works
Pastor‐Villaescusa, B., Rangel-Huerta, Ó. D., Aguilera, C. M., & Gil, Á. (2015) · Annals of Nutrition and Metabolism · doi:10.1159/000430960 · Cited by 24 · see citing works
Antiatherosclerotic and Cardioprotective Effects of Time-Released Garlic Powder Pills
Карагодин, В. П., Sobenin, I. A., & Orekhov, A. N. (2015) · Current Pharmaceutical Design · doi:10.2174/1381612822666151112153351 · Cited by 24 · see citing works
Self-citationAhmad, P., Alvi, S. S., & Khan, M. S. (2019) · Springer eBooks · doi:10.1007/978-981-13-7154-7_20 · Cited by 24 · see citing works
Safaeian, L., Zolfaghari, B., Karimi, S., Talebi, A., & Ghazvini, M. (2017) · Research in Pharmaceutical Sciences · doi:10.4103/1735-5362.220964 · Cited by 23 · see citing works
Blood Atherogenicity as a Target for Anti-atherosclerotic Therapy
Sobenin, I. A., Chistiakov, D. A., Bobryshev, Y. V., Postnov, A. Y., & Orekhov, A. N. (2013) · Current Pharmaceutical Design · doi:10.2174/1381612811319330014 · Cited by 23 · see citing works
Self-citationLi, S., Guo, W. F., Lau, W. W. Y., Zhang, H., Zhan, Z., Wang, X., & Wang, H. (2022) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2022.2053657 · Cited by 22 · see citing works
Herbal remedies, toxicity, and regulations
Oyedepo, T. A., & Palai, S. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-820284-5.00014-9 · Cited by 22 · see citing works
Gadidala, S. K., Johny, E., Thomas, C., Nadella, M., Undela, K., & Adela, R. (2023) · Phytotherapy Research · doi:10.1002/ptr.7729 · Cited by 21 · see citing works
Şaşmaz, H. K., Kadiroğlu, P., Adal, E., Sevindik, O., Aksay, Ö., Erkin, Ö. C., Selli, S., & Kelebek, H. (2023) · Journal of Applied Research on Medicinal and Aromatic Plants · doi:10.1016/j.jarmap.2023.100477 · Cited by 20 · see citing works
Du, Y., Zhou, H., & Zha, W. (2024) · Journal of Health Population and Nutrition · doi:10.1186/s41043-024-00608-1 · Cited by 18 · see citing works
Najman, K., Sadowska, A., Buczak, K., Hanna Leontowicz, A., & Maria Leontowicz, A. (2022) · Nutrients · doi:10.3390/nu14020336 · Cited by 18 · see citing works
The Role of Garlic in Metabolic Diseases: A Review
Pérez-Rubio, K. G., Villar, M. M.-D., & Cortez-Navarrete, M. (2022) · Journal of Medicinal Food · doi:10.1089/jmf.2021.0146 · Cited by 18 · see citing works
Koushki, M., Dashatan, N. A., Pourfarjam, Y., & Doustimotlagh, A. H. (2020) · Postgraduate Medical Journal · doi:10.1136/postgradmedj-2019-137267 · Cited by 18 · see citing works
Villaño, D., Marhuenda, J., Arcusa, R., Moreno‐Rojas, J. M., Cerdá, B., Pereira‐Caro, G., & Zafrilla, P. (2023) · Nutrients · doi:10.3390/nu15143138 · Cited by 17 · see citing works
Vezza, T., Guillamón, E., García-García, J., Baños, A., Mut‐Salud, N., García-López, J. D., Gómez-Fernández, G. O., Rodríguez‐Nogales, A., Gálvez, J., & Fonollá, J. (2024) · Nutrients · doi:10.3390/nu16162811 · Cited by 16 · see citing works
Functionality of garlic sulfur compounds (Review)
Seki, T., & Hosono, T. (2025) · Biomedical Reports · doi:10.3892/br.2025.2002 · Cited by 16 · see citing works
Inflammation in the CNS: Understanding Various Aspects of the Pathogenesis of Alzheimer's Disease
Doroszkiewicz, J., Mroczko, P., & Kulczyńska‐Przybik, A. (2021) · Current Alzheimer Research · doi:10.2174/1567205018666211202143935 · Cited by 14 · see citing works
NEUTRACEUTICAL POTENTIAL OF ORGANOSULFUR COMPOUNDS IN FRESH GARLIC AND GARLIC PREPARATIONS
Katare, C., Yogita, S., & Sonali, S. (2014) · International Journal of Pharma and Bio Sciences · Cited by 14 · see citing works
Kheirmandparizi, M., Keshavarz, P., Nowrouzi‐Sohrabi, P., Hosseini‐Bensenjan, M., Rezaei, S., Kashani, S. M. A., Zeidi, N., Tabrizi, R., & Alkamel, A. (2021) · International Journal of Clinical Practice · doi:10.1111/ijcp.14974 · Cited by 14 · see citing works
Effect of the Garlic Pill in comparison with Plavix on Platelet Aggregation and Bleeding Time.
Fakhar, H. R. E., & Tayer, A. H. (2012) · Europe PMC (PubMed Central) · Cited by 13 · see citing works
Foods of the Mediterranean diet: Garlic and Mediterranean legumes
Medori, M. C., Naureen, Z., Bonetti, G., Velluti, V., Aquilanti, B., Matera, G., Iaconelli, A., & Bertelli, M. (2022) · Journal of preventive medicine and hygiene · doi:10.15167/2421-4248/jpmh2022.63.2s3.2741 · Cited by 12 · see citing works
Ugwu, C. E., & Suru, S. M. (2016) · Journal of Biosciences and Medicines · doi:10.4236/jbm.2016.410004 · Cited by 12 · see citing works
Testing of serum atherogenicity in cell cultures: questionable data published
Jargin, S. V. (2012) · Europe PMC (PubMed Central) · doi:10.3205/000153 · Cited by 11 · see citing works
Cracking the Sulfur Code: Garlic Bioactive Molecules as Multi-Target Blueprints for Drug Discovery
Azam, F., Anwar, M. J., Kahfi, J., Almahmoud, S. A., & Emwas, A.-H. M. (2025) · Pharmaceuticals · doi:10.3390/ph18111766 · Cited by 10 · see citing works
Garlic and Its Effects on Health with Special Reference to the Reproductive System
Valente, C., Aboua, Y. G., & du Plessis, S. S. (2014) · InTech eBooks · doi:10.5772/57191 · Cited by 9 · see citing works
Ahmadv, H., Khosrowbeygi, A., & Ghasemi, M. (2011) · Journal of Medicinal Plants Research · doi:10.5897/jmpr.9000805 · Cited by 8 · see citing works
Behrouz, V., Zahroodi, M., Clark, C. C. T., Mir, E., Atashi, N., & Rivaz, R. (2025) · Nutrition Reviews · doi:10.1093/nutrit/nuaf090 · Cited by 7 · see citing works
Reduction of cholesterol and other cardiovascular disease risk factors by alternative therapies
Tappia, P. S., Xu, Y., & Dhalla, N. S. (2013) · Clinical Lipidology · doi:10.2217/clp.13.24 · Cited by 7 · see citing works
Piragine, E., Malanima, M. A., Ceccanti, C., Guidi, L., Martelli, A., Lucenteforte, E., & Calderone, V. (2024) · Phytotherapy Research · doi:10.1002/ptr.8350 · Cited by 6 · see citing works
Drug-dietary interaction potential of garlic on glimepiride treated type 2 diabetic Wistar rats
Mittal, P., & Juyal, V. K. (2012) · Journal of Diabetology · doi:10.4103/2078-7685.198083 · Cited by 5 · see citing works
Effectiveness ofAllium sativumon Bacterial Oral Infection
Karic, V., Jaiswal, A., Abrahamse, H., Thakur, A., & Ganeshpurkar, A. (2020) · doi:10.1002/9781119618973.ch22 · Cited by 5 · see citing works
Habtemariam, S. (2019) · Elsevier eBooks · doi:10.1016/b978-0-08-102922-0.00019-5 · Cited by 4 · see citing works
Orekhov`s Method: Reassessment of In vitro Lipid Uptake Assays
Jargin, S. V. (2015) · Recent Advances in Cardiovascular Drug Discovery (Formerly Recent Patents on Cardiovascular Drug Discovery) · doi:10.2174/1574890110666150707095340 · Cited by 4 · see citing works
Roles of Nutraceuticals and Functional Food in Prevention of Cardiovascular Disease
Hamid, S. B. S., & Hamid, A. F. A. (2018) · Advances in human services and public health (AHSPH) book series · doi:10.4018/978-1-5225-3267-5.ch005 · Cited by 4 · see citing works
Roles of garlic and its bioactive compounds in modulating cholesterol metabolism
Liang, N., Liu, J.-H., Li, Q., He, Z., Huang, X., & Chen, Z. (2025) · Phytomedicine · doi:10.1016/j.phymed.2025.157543 · Cited by 3 · see citing works
Dietary Factors and the Risk of Coronary Heart Disease
Kochar, J., Gaziano, J. M., & Djoussé, L. (2011) · Europe PMC (PubMed Central) · Cited by 3 · see citing works
Statin Alternatives: A Review of Over-the-Counter Lipid-Lowering Supplements
Danavi, J. V., Memon, S. B., & Phan, B. A. P. (2015) · Alternative and Complementary Therapies · doi:10.1089/act.2015.29018.jvd · Cited by 3 · see citing works
Quality Attributes of Some Vegetables and Fruits Preserved by Sun and Oven Drying Methods
Eshak, N. S. (2018) · Alexandria Science Exchange Journal · doi:10.21608/asejaiqjsae.2018.22785 · Cited by 3 · see citing works
Ghyasi, R., Moslehi, A., & Naderi, R. (2019) · Pharmaceutical Sciences · doi:10.15171/ps.2019.26 · Cited by 3 · see citing works
Apalowo, O. E., Adegoye, G. A., & Obuotor, T. M. (2024) · Bioactive Compounds in Health and Disease · doi:10.31989/7i2.1279 · Cited by 2 · see citing works
Parekh, N., Merota, V., Joshi, R., Kaur, G., Tuli, H. S., & Buttar, H. S. (2023) · Scripta Medica · doi:10.5937/scriptamed54-46932 · Cited by 2 · see citing works
Over-the-Counter Medications, Vitamins, Minerals, Biologicals, and Herbal Supplements
Bilder, G. E., & Brown-O’Hara, P. (2025) · Springer eBooks · doi:10.1007/978-3-031-84831-5_9 · Cited by 2 · see citing works
Tsalamandris, S., Oikonomou, E. K., Papamikroulis, G.-A., & Tousoulis, D. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-811908-2.00014-3 · Cited by 2 · see citing works
Peng, Q., Huang, P., Lv, B., Tang, C., Jin, H., & Huang, Y. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1502269 · Cited by 1 · see citing works
Medicinal and Nutritional Importance of Garlic (Allium sativum L.) Human Health
Rather, G. A., Bhat, M. Y., Dar, M. I., Sofi, M. A., Yadav, R., Nazneen, H., & Abid, A. (2026) · Springer eBooks · doi:10.1007/978-981-95-3620-7_9 · Cited by 1 · see citing works
Effectiveness of Garlic Tablet Compared with Rifampin in the Treatment of Brucellosis
Farazi, A., Zarinfar, N., & Mirzajani, P. (2014) · Cited by 1 · see citing works
Intracellular Cholesterol Lowering as Novel Target for Anti‐Atherosclerotic Therapy
Orekhov, A. N., & Ivanova, E. A. (2016) · InTech eBooks · doi:10.5772/64363 · Cited by 1 · see citing works
Self-citationMcQueen, C. E., & Orr, K. K. (2015) · The American Pharmacists Association eBooks · doi:10.21019/9781582122250.ch51 · Cited by 1 · see citing works
Farhad, G., Ebrahim, K., Sajjad, A., Saeed, D. N., & Adel, R. (2013) · Medical Journal of Tabriz University of Medical Sciences and Health Services · Cited by 1 · see citing works
Mehdi, A., Siahkouhian, M., & Imani, A. (2016) · Cited by 1 · see citing works
ROLE OF GARLIC IN GERIATRIC DISORDERS – A REVIEW
Yadav, V., & Yadav, V. M. (2018) · National Journal of Research in Ayurved Science · doi:10.52482/ayurlog.v6i07.246 · Cited by 1 · see citing works
Garlic in Cardiovascular Health
Banerjee, S., & Maulik, S. K. (2013) · CRC Press eBooks · doi:10.1201/b14663-25
Lipid Profiles are Altered in Rats Fed with Different Garlic Cultivars
da Silva, E. Y. Y., Brasilia, D., Moretti, C. L., Embrapa, P. E. B. B., Mattos, L. M., & Embrapa, P. E. B. B. (2015) · International Journal of Biomedicine · doi:10.21103/article5(3)_oa9
Orekhov, A. N., Grechko, A. V., Romanenko, E. B., Zhang, D., & Chistiakov, D. A. (2019) · Current Drug Discovery Technologies · doi:10.2174/1570163816666190101112241
Self-citationRoles of Nutraceuticals and Functional Food in Prevention of Cardiovascular Disease
Hamid, S. B. S., & Hamid, A. F. A. (2021) · IGI Global eBooks · doi:10.4018/978-1-6684-3546-5.ch041
Siddiqa, A., Basharat, S., Mubarik, F., Farooq, F., & Ali, M. (2022) · Pakistan BioMedical Journal · doi:10.54393/pbmj.v5i1.110
Siddiqa, A., Basharat, S., Mubarik, F., Farooq, F., & Ali, M. (2022) · Pakistan BioMedical Journal · doi:10.54393/pbmj.v5i2.110
Chandio, S., Memon, S. H., Maria, Mangi, N. Z., Ujjan, I. U., & Raza, A. (2021) · SINDH UNIVERSITY RESEARCH JOURNAL -SCIENCE SERIES · doi:10.26692/surj.v53i04.4218
- Authors
- Sobenin, I. A., Pryanishnikov, V. V., Kunnova, L. M., Rabinovich, Y. A., Martirosyan, D. M., & Orekhov, A. N.
- Affiliations
- Research Institute of General Pathology and Pathophysiology, the Russian Academy of Medical Sciences (RU)
- Corresponding author
- Sobenin, Igor A
- Venue
- Lipids in Health and Disease
- Published
- 2010
- Volume
- 9
- Issue
- 1
- Pages
- 119
- ISSN
- 1476-511X (ISSN-L)
- PMC
- PMC2972277
- OpenAlex
- W2028736925
- Cited by
- 114
- References
- 35
- Citations by year
- 2026: 3 · 2025: 9 · 2024: 6 · 2023: 8 · 2022: 13 · 2021: 10 · 2020: 6 · 2019: 7 · 2018: 8 · 2017: 2 · 2016: 9 · 2015: 9 · 2014: 7 · 2013: 7 · 2012: 5
- FWCI
- 6.52
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Lipids in Health and Disease (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Garlic and Onion Studies
- Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Botanical Studies and Applications
- Keywords
- coronary artery disease, cardiovascular risk, secondary prevention, acute myocardial infarction, sudden death, LDL cholesterol, sex differences, atherosclerosis
- MeSH terms
- Adult, Aged, Antioxidants, Coronary Artery Disease, Double-Blind Method, Female, Garlic, Humans, Cholesterol, LDL, Male, Middle Aged, Sex Factors, Tablets, Treatment Outcome
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
