Clear cell carcinoma arising from abdominal wall endometriosis: a unique case with bladder and lymph node metastasis
Open accessAbstract
The malignant transformation of abdominal wall endometriosis is a rare event and poorly understood. Less than 30 cases have been reported in the literature. Most of the reported cases have a solitary tumor in the abdominal scar. A few cases have metastasis. Here we report a case of clear cell carcinoma in abdominal wall endometriosis with bladder and lymph system metastasis. The patient had a history of abdominal wall endometriosis and recently developed symptoms of urgent urination and inguinal mass. Physical examination and a computed tomography (CT) scan detected lymph node metastasis. CT and cystoscopy confirmed bladder involvement. The patient underwent extensive surgery and chemotherapy. Pathological analysis made a diagnosis of clear cell carcinoma with bladder and lymph node metastasis. The patient was followed up and died of the disease. Symptoms of bladder invasion and lymph node spread could be a sign of malignant transformation. Local invasion and lymph node spread are two important forms of tumor metastasis. Extensive lymph nodes metastasis might be related with poor prognosis.
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Lymph node dissection is considered when pre-operative imaging demonstrates suspicious nodes or nodal involvement.
“Lymph node dissection is considered when pre-operative imaging demonstrates suspicious nodes or nodal involvement [24].”
From Clear cell carcinoma arising from abdominal wall endometriosis—A report on two cases and literature review (2022) · cites this paper as [24]
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- Authors
- Liu, H., Leng, J., Lang, J., & Cui, Q.
- Affiliations
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Corresponding author
- Liu, Haiyuan
- Venue
- World Journal of Surgical Oncology
- Published
- 2014
- Volume
- 12
- Issue
- 1
- Pages
- 51
- ISSN
- 1477-7819 (ISSN-L)
- PMC
- PMC3973880
- OpenAlex
- W1973974952
- Cited by
- 36
- References
- 11
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 2 · 2023: 2 · 2022: 2 · 2021: 6 · 2020: 2 · 2019: 4 · 2018: 3 · 2017: 3 · 2016: 5 · 2015: 4
- FWCI
- 4.86
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- World Journal of Surgical Oncology (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- Peking Union Medical College Hospital
- Peking Union Medical College
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Metastasis and carcinoma case studies
- Health Sciences › Medicine › Surgery › Urinary and Genital Oncology Studies
- Keywords
- clear cell carcinoma, abdominal wall endometriosis, malignant transformation, bladder metastasis, lymph node metastasis, endometriosis-associated cancer, cystoscopy, prognosis
- MeSH terms
- Abdominal Neoplasms, Adult, Antineoplastic Combined Chemotherapy Protocols, Urinary Bladder Neoplasms, Combined Modality Therapy, Endometriosis, Female, Humans, Lymphatic Metastasis, Prognosis, Tomography, X-Ray Computed, Adenocarcinoma, Clear Cell
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