CoChat
Sign Up
Cited by 154

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Recent progress in understanding protein and lipid factors affecting hepatic VLDL assembly and secretion

Sundaram, Meenakshi, Yao, Zemin·2010·Nutrition & Metabolism
DOI 10.1186/1743-7075-7-35PMC PMC2873297
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1186/1743-7075-7-35

Cites

4 of 4 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 169

  1. Law SW Lackner KJ Hospattankar AV Anchors JM Sakaguchi AY Naylor SL Brewer HB Jr Human apolipoprotein B-100: cloning, analysis of liver mRNA, and assignment of the gene to chromosome 2 Proc Natl Acad Sci USA 1985 82 8340 8344 10.1073/pnas.82.24.8340 3001697 PMC390911 · DOI
  2. Lusis AJ West R Mehrabian M Reuben MA LeBoeuf RC Kaptein JS Johnson DF Schumaker VN Yuhasz MP Schotz MC Cloning and expression of apolipoprotein B, the major protein of low and very low density lipoproteins Proc Natl Acad Sci USA 1985 82 4597 4601 10.1073/pnas.82.14.4597 3860811 PMC390432 · DOI
  3. Deeb SS Disteche C Motulsky AG Lebo RV Kan YW Chromosomal localization of the human apolipoprotein B gene and detection of homologous RNA in monkey intestine Proc Natl Acad Sci USA 1986 83 419 422 10.1073/pnas.83.2.419 3455779 PMC322870 · DOI
  4. Chen SH Habib G Yang CY Gu ZW Lee BR Weng SA Silberman SR Cai SJ Deslypere JP Rosseneu M Apolipoprotein B-48 is the product of a messenger RNA with an organ-specific in-frame stop codon Science 1987 238 363 366 10.1126/science.3659919 3659919 · DOI
  5. Kane JP Hardman DA Paulus HE Heterogeneity of apolipoprotein B: isolation of a new species from human chylomicrons Proc Natl Acad Sci USA 1980 77 2465 2469 10.1073/pnas.77.5.2465 6930644 PMC349420 · DOI
  6. Tennyson GE Sabatos CA Higuchi K Meglin N Brewer HB Jr Expression of apolipoprotein B mRNAs encoding higher- and lower-molecular weight isoproteins in rat liver and intestine Proc Natl Acad Sci USA 1989 86 500 504 10.1073/pnas.86.2.500 2911593 PMC286498 · DOI
  7. Segrest JP Jones MK De LH Dashti N Structure of apolipoprotein B-100 in low density lipoproteins J Lipid Res 2001 42 1346 1367 11518754
  8. Mann CJ Anderson TA Read J Chester SA Harrison GB Kochl S Ritchie PJ Bradbury P Hussain FS Amey J The structure of vitellogenin provides a molecular model for the assembly and secretion of atherogenic lipoproteins J Mol Biol 1999 285 391 408 10.1006/jmbi.1998.2298 9878414 · DOI
  9. Jiang ZG Gantz D Bullitt E McKnight CJ Defining lipid-interacting domains in the N-terminal region of apolipoprotein B Biochemistry 2006 45 11799 11808 10.1021/bi060600w 17002280 PMC2519233 · DOI
  10. Dashti N Gandhi M Liu X Lin X Segrest JP The N-terminal 1000 residues of apolipoprotein B associate with microsomal triglyceride transfer protein to create a lipid transfer pocket required for lipoprotein assembly Biochemistry 2002 41 6978 6987 10.1021/bi011757l 12033930 · DOI
  11. Jiang ZG Simon MN Wall JS McKnight CJ Structural analysis of reconstituted lipoproteins containing the N-terminal domain of apolipoprotein B Biophys J 2007 92 4097 4108 10.1529/biophysj.106.101105 17369413 PMC1868998 · DOI
  12. Ren G Rudenko G Ludtke SJ Deisenhofer J Chiu W Pownall HJ Model of human low-density lipoprotein and bound receptor based on cryoEM Proc Natl Acad Sci USA 2010 107 1059 1064 10.1073/pnas.0908004107 20080547 PMC2798884 · DOI
  13. Hussain MM Bakillah A Nayak N Shelness GS Amino acids 430-570 in apolipoprotein B are critical for its binding to microsomal triglyceride transfer protein J Biol Chem 1998 273 25612 25615 10.1074/jbc.273.40.25612 9748226 · DOI
  14. Segrest JP Jones MK Dashti N N-terminal domain of apolipoprotein B has structural homology to lipovitellin and microsomal triglyceride transfer protein: a "lipid pocket" model for self-assembly of apob-containing lipoprotein particles J Lipid Res 1999 40 1401 1416 10428976
  15. Liang J Ginsberg HN Microsomal triglyceride transfer protein binding and lipid transfer activities are independent of each other, but both are required for secretion of apolipoprotein B lipoproteins from liver cells J Biol Chem 2001 276 28606 28612 10.1074/jbc.M100294200 11358959 · DOI
  16. Bradbury P Mann CJ Kochl S Anderson TA Chester SA Hancock JM Ritchie PJ Amey J Harrison GB Levitt DG A common binding site on the microsomal triglyceride transfer protein for apolipoprotein B and protein disulfide isomerase J Biol Chem 1999 274 3159 3164 10.1074/jbc.274.5.3159 9915855 · DOI
  17. Hussain MM Bakillah A Jamil H Apolipoprotein B binding to microsomal triglyceride transfer protein decreases with increases in length and lipidation: implications in lipoprotein biosynthesis Biochemistry 1997 36 13060 13067 10.1021/bi971395a 9335568 · DOI
  18. Kreuzer J White AL Knott TJ Jien ML Mehrabian M Scott J Young SG Haberland ME Amino terminus of apolipoprotein B suffices to produce recognition of malondialdehyde-modified low density lipoprotein by the scavenger receptor of human monocyte-macrophages J Lipid Res 1997 38 324 342 9162752
  19. Sivaram P Choi SY Curtiss LK Goldberg IJ An amino-terminal fragment of apolipoprotein B binds to lipoprotein lipase and may facilitate its binding to endothelial cells J Biol Chem 1994 269 9409 9412 8144523
  20. Shelness GS Hou L Ledford AS Parks JS Weinberg RB Identification of the lipoprotein initiating domain of apolipoprotein B J Biol Chem 2003 278 44702 44707 10.1074/jbc.M307562200 12941937 · DOI
  21. Wang L Martin DD Genter E Wang J McLeod RS Small DM Surface study of apoB1694-1880, a sequence that can anchor apoB to lipoproteins and make it nonexchangeable J Lipid Res 2009 50 1340 1352 10.1194/jlr.M900040-JLR200 19251580 PMC2694333 · DOI
  22. Hospattankar AV Law SW Lackner K Brewer HB Jr Identification of low density lipoprotein receptor binding domains of human apolipoprotein B-100: a proposed consensus LDL receptor binding sequence of apoB-100 Biochem Biophys Res Commun 1986 139 1078 1085 10.1016/S0006-291X(86)80287-X 3767991 · DOI
  23. Yang CY Chen SH Gianturco SH Bradley WA Sparrow JT Tanimura M Li WH Sparrow DA DeLoof H Rosseneu M Sequence, structure, receptor-binding domains and internal repeats of human apolipoprotein B-100 Nature 1986 323 738 742 10.1038/323738a0 3095664 · DOI
  24. Wang L Walsh MT Small DM Apolipoprotein B is conformationally flexible but anchored at a triolein/water interface: a possible model for lipoprotein surfaces Proc Natl Acad Sci USA 2006 103 6871 6876 10.1073/pnas.0602213103 16636271 PMC1458986 · DOI
  25. Gretch DG Sturley SL Wang L Lipton BA Dunning A Grunwald KA Wetterau JR Yao Z Talmud P Attie AD The amino terminus of apolipoprotein B is necessary but not sufficient for microsomal triglyceride transfer protein responsiveness J Biol Chem 1996 271 8682 8691 10.1074/jbc.271.15.8682 8621500 · DOI
  26. McLeod RS Wang Y Wang S Rusinol A Links P Yao Z Apolipoprotein B sequence requirements for hepatic very low density lipoprotein assembly. Evidence that hydrophobic sequences within apolipoprotein B48 mediate lipid recruitment J Biol Chem 1996 271 18445 18455 10.1074/jbc.271.24.14124 8702489 · DOI · Paper page
  27. Liang J Wu X Jiang H Zhou M Yang H Angkeow P Huang LS Sturley SL Ginsberg H Translocation efficiency, susceptibility to proteasomal degradation, and lipid responsiveness of apolipoprotein B are determined by the presence of beta sheet domains J Biol Chem 1998 273 35216 35221 10.1074/jbc.273.52.35216 9857060 · DOI
  28. Tran K Boren J Macri J Wang Y McLeod R Avramoglu RK Adeli K Yao Z Functional analysis of disulfide linkages clustered within the amino terminus of human apolipoprotein B J Biol Chem 1998 273 7244 7251 10.1074/jbc.273.13.7244 9516417 · DOI
  29. Huang XF Shelness GS Identification of cysteine pairs within the amino-terminal 5% of apolipoprotein B essential for hepatic lipoprotein assembly and secretion J Biol Chem 1997 272 31872 31876 10.1074/jbc.272.50.31872 9395534 · DOI
  30. Ingram MF Shelness GS Apolipoprotein B-100 destined for lipoprotein assembly and intracellular degradation undergoes efficient translocation across the endoplasmic reticulum membrane J Lipid Res 1996 37 2202 2214 8906597
  31. Taniguchi T Ishikawa Y Tsunemitsu M Fukuzaki H The structures of the asparagine-linked sugar chains of human apolipoprotein B-100 Arch Biochem Biophys 1989 273 197 205 10.1016/0003-9861(89)90179-3 2757392 · DOI
  32. Vukmirica J Nishimaki-Mogami T Tran K Shan J McLeod RS Yuan J Yao Z The N-linked oligosaccharides at the amino terminus of human apoB are important for the assembly and secretion of VLDL J Lipid Res 2002 43 1496 1507 10.1194/jlr.M200077-JLR200 12235182 · DOI
  33. Dunphy JT Linder ME Signalling functions of protein palmitoylation Biochim Biophys Acta 1998 1436 245 261 9838145
  34. Hoeg JM Meng MS Ronan R Demosky SJ Jr Fairwell T Brewer HB Jr Apolipoprotein B synthesized by Hep G2 cells undergoes fatty acid acylation J Lipid Res 1988 29 1215 1220 2846736
  35. Zhao Y McCabe JB Vance J Berthiaume LG Palmitoylation of apolipoprotein B is required for proper intracellular sorting and transport of cholesteroyl esters and triglycerides Mol Biol Cell 2000 11 721 734 10679026 PMC14805
  36. Vukmirica J Tran K Liang X Shan J Yuan J Miskie BA Hegele RA Resh MD Yao Z Assembly and secretion of very low density lipoproteins containing apolipoprotein B48 in transfected McA-RH7777 cells. Lack of evidence that palmitoylation of apolipoprotein B48 is required for lipoprotein secretion J Biol Chem 2003 278 14153 14161 10.1074/jbc.M211995200 12582154 · DOI
  37. Schonfeld G Familial hypobetalipoproteinemia: a review J Lipid Res 2003 44 878 883 10.1194/jlr.R300002-JLR200 12639976 · DOI
  38. Heiss G Tamir I Davis CE Tyroler HA Rifkand BM Schonfeld G Jacobs D Frantz ID Jr Lipoprotein-cholesterol distributions in selected North American populations: the lipid research clinics program prevalence study Circulation 1980 61 302 315 7351055
  39. McCormick SP Fellowes AP Walmsley TA George PM Apolipoprotein B-32: a new truncated mutant of human apolipoprotein B capable of forming particles in the low density lipoprotein range Biochim Biophys Acta 1992 1138 290 296 1562615
  40. Wagner RD Krul ES Tang J Parhofer KG Garlock K Talmud P Schonfeld G ApoB-54.8, a truncated apolipoprotein found primarily in VLDL, is associated with a nonsense mutation in the apoB gene and hypobetalipoproteinemia J Lipid Res 1991 32 1001 1011 1940616
  41. Pullinger CR Hillas E Hardman DA Chen GC Naya-Vigne JM Iwasa JA Hamilton RL Lalouel JM Williams RR Kane JP Two apolipoprotein B gene defects in a kindred with hypobetalipoproteinemia, one of which results in a truncated variant, apoB-61, in VLDL and LDL J Lipid Res 1992 33 699 710 1619363
  42. Krul ES Parhofer KG Barrett PH Wagner RD Schonfeld G ApoB-75, a truncation of apolipoprotein B associated with familial hypobetalipoproteinemia: genetic and kinetic studies J Lipid Res 1992 33 1037 1050 1431583
  43. Farese RV Jr Garg A Pierotti VR Vega GL Young SG A truncated species of apolipoprotein B, B-83, associated with hypobetalipoproteinemia J Lipid Res 1992 33 569 577 1527480
  44. Fouchier SW Sankatsing RR Peter J Castillo S Pocovi M Alonso R Kastelein JJ Defesche JC High frequency of APOB gene mutations causing familial hypobetalipoproteinaemia in patients of Dutch and Spanish descent J Med Genet 2005 42 e23 10.1136/jmg.2004.029454 15805152 PMC1736043 · DOI
  45. Chen Z Fitzgerald RL Schonfeld G Hypobetalipoproteinemic mice with a targeted apolipoprotein (Apo) B-27.6-specifying mutation: in vivo evidence for an important role of amino acids 1254-1744 of ApoB in lipid transport and metabolism of the apoB-containing lipoprotein J Biol Chem 2002 277 14135 14145 11839763
  46. McLeod RS Zhao Y Selby SL Westerlund J Yao Z Carboxyl-terminal truncation impairs lipid recruitment by apolipoprotein B100 but does not affect secretion of the truncated apolipoprotein B-containing lipoproteins J Biol Chem 1994 269 2852 2862 8300620
  47. Burnett JR Shan J Miskie BA Whitfield AJ Yuan J Tran K McKnight CJ Hegele RA Yao Z A novel nontruncating APOB gene mutation, R463W, causes familial hypobetalipoproteinemia J Biol Chem 2003 278 13442 13452 10.1074/jbc.M300235200 12551903 · DOI
  48. Burnett JR Zhong S Jiang ZG Hooper AJ Fisher EA McLeod RS Zhao Y Barrett PH Hegele RA van Bockxmeer FM Missense mutations in APOB within the betaalpha1 domain of human APOB-100 result in impaired secretion of ApoB and ApoB-containing lipoproteins in familial hypobetalipoproteinemia J Biol Chem 2007 282 24270 24283 10.1074/jbc.M702442200 17588943 · DOI
  49. Tarugi P Averna M Di LE Cefalu AB Noto D Magnolo L Cattin L Bertolini S Calandra S Molecular diagnosis of hypobetalipoproteinemia: an ENID review Atherosclerosis 2007 195 e19 e27 10.1016/j.atherosclerosis.2007.05.003 17570373 · DOI
  50. Zhong S Magnolo AL Sundaram M Zhou H Yao EF Di LE Loria P Wang S Bamji-Mirza M Wang L Nonsynonymous mutations within APOB in human familial hypobetalipoproteinemia: evidence for feedback inhibition of lipogenesis and postendoplasmic reticulum degradation of apolipoprotein B J Biol Chem 2010 285 6453 6464 10.1074/jbc.M109.060467 20032471 PMC2825441 · DOI
  51. Jamil H Dickson JK Jr Chu CH Lago MW Rinehart JK Biller SA Gregg RE Wetterau JR Microsomal triglyceride transfer protein. Specificity of lipid binding and transport J Biol Chem 1995 270 6549 6554 10.1074/jbc.270.12.6549 7896791 · DOI
  52. Wetterau JR Combs KA Spinner SN Joiner BJ Protein disulfide isomerase is a component of the microsomal triglyceride transfer protein complex J Biol Chem 1990 265 9800 9807 2351674
  53. Wang L Fast DG Attie AD The enzymatic and non-enzymatic roles of protein-disulfide isomerase in apolipoprotein B secretion J Biol Chem 1997 272 27644 27651 10.1074/jbc.272.44.27644 9346903 · DOI
  54. Wetterau JR Aggerbeck LP Bouma ME Eisenberg C Munck A Hermier M Schmitz J Gay G Rader DJ Gregg RE Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia Science 1992 258 999 1001 10.1126/science.1439810 1439810 · DOI
  55. Read J Anderson TA Ritchie PJ Vanloo B Amey J Levitt D Rosseneu M Scott J Shoulders CC A mechanism of membrane neutral lipid acquisition by the microsomal triglyceride transfer protein J Biol Chem 2000 275 30372 30377 10.1074/jbc.C000364200 10893406 · DOI
  56. Zhou M Fisher EA Ginsberg HN Regulated Co-translational ubiquitination of apolipoprotein B100. A new paradigm for proteasomal degradation of a secretory protein J Biol Chem 1998 273 24649 24653 10.1074/jbc.273.38.24649 9733761 · DOI · Paper page
  57. Wang Y Tran K Yao Z The activity of microsomal triglyceride transfer protein is essential for accumulation of triglyceride within microsomes in McA-RH7777 cells. A unified model for the assembly of very low density lipoproteins J Biol Chem 1999 274 27793 27800 10.1074/jbc.274.39.27793 10488124 · DOI
  58. Rustaeus S Stillemark P Lindberg K Gordon D Olofsson SO The microsomal triglyceride transfer protein catalyzes the post-translational assembly of apolipoprotein B-100 very low density lipoprotein in McA-RH7777 cells J Biol Chem 1998 273 5196 5203 10.1074/jbc.273.9.5196 9478974 · DOI
  59. Gordon DA Jamil H Progress towards understanding the role of microsomal triglyceride transfer protein in apolipoprotein-B lipoprotein assembly Biochim Biophys Acta 2000 1486 72 83 10856714
  60. Wang Y McLeod RS Yao Z Normal activity of microsomal triglyceride transfer protein is required for the oleate-induced secretion of very low density lipoproteins containing apolipoprotein B from McA-RH7777 cells J Biol Chem 1997 272 12272 12278 10.1074/jbc.272.19.12272 9139669 · DOI
  61. Kulinski A Rustaeus S Vance JE Microsomal triacylglycerol transfer protein is required for lumenal accretion of triacylglycerol not associated with ApoB, as well as for ApoB lipidation J Biol Chem 2002 277 31516 31525 10.1074/jbc.M202015200 12072432 · DOI
  62. Hebbachi A Gibbons GF Inactivation of microsomal triglyceride transfer protein impairs the normal redistribution but not the turnover of newly synthesized glycerolipid in the cytosol, endoplasmic reticulum and Golgi of primary rat hepatocytes Biochim Biophys Acta 1999 1441 36 50 10526226
  63. Chang BH Liao W Li L Nakamuta M Mack D Chan L Liver-specific inactivation of the abetalipoproteinemia gene completely abrogates very low density lipoprotein/low density lipoprotein production in a viable conditional knockout mouse J Biol Chem 1999 274 6051 6055 10.1074/jbc.274.10.6051 10037685 · DOI
  64. Raabe M Veniant MM Sullivan MA Zlot CH Bjorkegren J Nielsen LB Wong JS Hamilton RL Young SG Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice J Clin Invest 1999 103 1287 1298 10.1172/JCI6576 10225972 PMC408359 · DOI · Paper page
  65. Spann NJ Kang S Li AC Chen AZ Newberry EP Davidson NO Hui ST Davis RA Coordinate transcriptional repression of liver fatty acid-binding protein and microsomal triglyceride transfer protein blocks hepatic very low density lipoprotein secretion without hepatosteatosis J Biol Chem 2006 281 33066 33077 10.1074/jbc.M607148200 16950764 · DOI
  66. Huang J Iqbal J Saha PK Liu J Chan L Hussain MM Moore DD Wang L Molecular characterization of the role of orphan receptor small heterodimer partner in development of fatty liver Hepatology 2007 46 147 157 10.1002/hep.21632 17526026 · DOI
  67. Hribal ML Nakae J Kitamura T Shutter JR Accili D Regulation of insulin-like growth factor-dependent myoblast differentiation by Foxo forkhead transcription factors J Cell Biol 2003 162 535 541 10.1083/jcb.200212107 12925703 PMC2173790 · DOI
  68. Kamagate A Qu S Perdomo G Su D Kim DH Slusher S Meseck M Dong HH FoxO1 mediates insulin-dependent regulation of hepatic VLDL production in mice J Clin Invest 2008 118 2347 2364 18497885 PMC2391277
  69. Wolfrum C Stoffel M Coactivation of Foxa2 through Pgc-1beta promotes liver fatty acid oxidation and triglyceride/VLDL secretion Cell Metab 2006 3 99 110 10.1016/j.cmet.2006.01.001 16459311 · DOI
  70. Dolinsky VW Douglas DN Lehner R Vance DE Regulation of the enzymes of hepatic microsomal triacylglycerol lipolysis and re-esterification by the glucocorticoid dexamethasone Biochem J 2004 378 967 974 10.1042/BJ20031320 14662008 PMC1224021 · DOI
  71. Tran K Wang Y DeLong CJ Cui Z Yao Z The assembly of very low density lipoproteins in rat hepatoma McA-RH7777 cells is inhibited by phospholipase A2 antagonists J Biol Chem 2000 275 25023 25030 10.1074/jbc.M908971199 10827200 · DOI
  72. Tran K Sun F Cui Z Thorne-Tjomsland G St GC Lapierre LR McLeod RS Jamieson JC Yao Z Attenuated secretion of very low density lipoproteins from McA-RH7777 cells treated with eicosapentaenoic acid is associated with impaired utilization of triacylglycerol synthesized via phospholipid remodeling Biochim Biophys Acta 2006 1761 463 473 16675301
  73. Robichaud JC van d V Yao Z Trigatti B Vance DE Hepatic uptake and metabolism of phosphatidylcholine associated with high density lipoproteins Biochim Biophys Acta 2009 1790 538 551 19250958
  74. Sato K Cho Y Tachibana S Chiba T Schneider WJ Akiba Y Impairment of VLDL secretion by medium-chain fatty acids in chicken primary hepatocytes is affected by the chain length J Nutr 2005 135 1636 1641 15987842
  75. Tachibana S Sato K Cho Y Chiba T Schneider WJ Akiba Y Octanoate reduces very low-density lipoprotein secretion by decreasing the synthesis of apolipoprotein B in primary cultures of chicken hepatocytes Biochim Biophys Acta 2005 1737 36 43 16226916
  76. Sundaram M Zhong S Bou Khalil M Links PH Zhao Y Iqbal J Hussain MM Parks RJ Wang Y Yao Z Expression of apolipoprotein C-III in McA-RH7777 cells enhances VLDL assembly and secretion under lipid-rich conditions J Lipid Res 2010 51 150 161 10.1194/M900346-JLR200 19622837 PMC2789775 · DOI
  77. Tran K Thorne-Tjomsland G DeLong CJ Cui Z Shan J Burton L Jamieson JC Yao Z Intracellular assembly of very low density lipoproteins containing apolipoprotein B100 in rat hepatoma McA-RH7777 cells J Biol Chem 2002 277 31187 31200 10.1074/jbc.M200249200 12065576 · DOI
  78. Lopez-Soldado I Avella M Botham KM Differential influence of different dietary fatty acids on very low-density lipoprotein secretion when delivered to hepatocytes in chylomicron remnants Metabolism 2009 58 186 195 10.1016/j.metabol.2008.09.012 19154951 PMC2779336 · DOI
  79. Pal S Takechi R Ho SS Conjugated linoleic acid suppresses the secretion of atherogenic lipoproteins from human HepG2 liver cells Clin Chem Lab Med 2005 43 269 274 10.1515/CCLM.2005.045 15843229 · DOI
  80. Zhang P Boudyguina E Wilson MD Gebre AK Parks JS Echium oil reduces plasma lipids and hepatic lipogenic gene expression in apoB100-only LDL receptor knockout mice J Nutr Biochem 2008 19 655 663 10.1016/j.jnutbio.2007.08.005 18155507 PMC2610363 · DOI
  81. Werner A Havinga R Bos T Bloks VW Kuipers F Verkade HJ Essential fatty acid deficiency in mice is associated with hepatic steatosis and secretion of large VLDL particles Am J Physiol Gastrointest Liver Physiol 2005 288 G1150 G1158 10.1152/ajpgi.00456.2004 15662048 · DOI
  82. Degrace P Moindrot B Mohamed I Gresti J Du ZY Chardigny JM Sebedio JL Clouet P Upregulation of liver VLDL receptor and FAT/CD36 expression in LDLR-/- apoB100/100 mice fed trans-10,cis-12 conjugated linoleic acid J Lipid Res 2006 47 2647 2655 10.1194/jlr.M600140-JLR200 16957181 · DOI
  83. Ota T Gayet C Ginsberg HN Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents J Clin Invest 2008 118 316 332 10.1172/JCI32752 18060040 PMC2104481 · DOI
  84. Su Q Tsai J Xu E Qiu W Bereczki E Santha M Adeli K Apolipoprotein B100 acts as a molecular link between lipid-induced endoplasmic reticulum stress and hepatic insulin resistance Hepatology 2009 50 77 84 10.1002/hep.22960 19434737 · DOI
  85. Carman GM Han GS Roles of phosphatidate phosphatase enzymes in lipid metabolism Trends Biochem Sci 2006 31 694 699 10.1016/j.tibs.2006.10.003 17079146 PMC1769311 · DOI
  86. Peterfy M Phan J Xu P Reue K Lipodystrophy in the fld mouse results from mutation of a new gene encoding a nuclear protein, lipin Nat Genet 2001 27 121 124 10.1038/83685 11138012 · DOI
  87. Donkor J Sariahmetoglu M Dewald J Brindley DN Reue K Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns J Biol Chem 2007 282 3450 3457 10.1074/jbc.M610745200 17158099 · DOI
  88. Peterfy M Phan J Reue K Alternatively spliced lipin isoforms exhibit distinct expression pattern, subcellular localization, and role in adipogenesis J Biol Chem 2005 280 32883 32889 10.1074/jbc.M503885200 16049017 · DOI
  89. Manmontri B Sariahmetoglu M Donkor J Bou Khalil M Sundaram M Yao Z Reue K Lehner R Brindley DN Glucocorticoids and cyclic AMP selectively increase hepatic lipin-1 expression, and insulin acts antagonistically J Lipid Res 2008 49 1056 1067 10.1194/jlr.M800013-JLR200 18245816 PMC2311443 · DOI
  90. Bou Khlail M Sundaram M Zhang HY Links PH Raven JF Manmontri B Sariahmetoglu M Tran K Reue K Brindley DN The level and compartmentalization of phosphatidate phosphatase-1 (lipin-1) control the assembly and secretion of hepatic VLDL J Lipid Res 2009 50 47 58 18769019
  91. Chen Z Gropler MC Norris J Lawrence JC Jr Harris TE Finck BN Alterations in hepatic metabolism in fld mice reveal a role for lipin 1 in regulating VLDL-triacylglyceride secretion Arterioscler Thromb Vasc Biol 2008 28 1738 1744 10.1161/ATVBAHA.108.171538 18669885 PMC2655237 · DOI
  92. Finck BN Gropler MC Chen Z Leone TC Croce MA Harris TE Lawrence JC Jr Kelly DP Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway Cell Metab 2006 4 199 210 10.1016/j.cmet.2006.08.005 16950137 · DOI
  93. Cases S Smith SJ Zheng YW Myers HM Lear SR Sande E Novak S Collins C Welch CB Lusis AJ Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis Proc Natl Acad Sci USA 1998 95 13018 13023 10.1073/pnas.95.22.13018 9789033 PMC23692 · DOI
  94. Smith SJ Cases S Jensen DR Chen HC Sande E Tow B Sanan DA Raber J Eckel RH Farese RV Jr Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat Nat Genet 2000 25 87 90 10.1038/75651 10802663 · DOI
  95. Millar JS Stone SJ Tietge UJ Tow B Billheimer JT Wong JS Hamilton RL Farese RV Jr Rader DJ Short-term overexpression of DGAT1 or DGAT2 increases hepatic triglyceride but not VLDL triglyceride or apoB production J Lipid Res 2006 47 2297 2305 10.1194/jlr.M600213-JLR200 16877777 · DOI
  96. Liang JJ Oelkers P Guo C Chu PC Dixon JL Ginsberg HN Sturley SL Overexpression of human diacylglycerol acyltransferase 1, acyl-coa:cholesterol acyltransferase 1, or acyl-CoA:cholesterol acyltransferase 2 stimulates secretion of apolipoprotein B-containing lipoproteins in McA-RH7777 cells J Biol Chem 2004 279 44938 44944 10.1074/jbc.M408507200 15308631 · DOI
  97. Yamazaki T Sasaki E Kakinuma C Yano T Miura S Ezaki O Increased very low density lipoprotein secretion and gonadal fat mass in mice overexpressing liver DGAT1 J Biol Chem 2005 280 21506 21514 10.1074/jbc.M412989200 15797871 · DOI · Paper page
  98. Liu Y Millar JS Cromley DA Graham M Crooke R Billheimer JT Rader DJ Knockdown of acyl-CoA:diacylglycerol acyltransferase 2 with antisense oligonucleotide reduces VLDL TG and ApoB secretion in mice Biochim Biophys Acta 2008 1781 97 104 18252207
  99. Walkey CJ Donohue LR Bronson R Agellon LB Vance DE Disruption of the murine gene encoding phosphatidylethanolamine N-methyltransferase Proc Natl Acad Sci USA 1997 94 12880 12885 10.1073/pnas.94.24.12880 9371769 PMC24232 · DOI
  100. Zhao Y Su B Jacobs RL Kennedy B Francis GA Waddington E Brosnan JT Vance JE Vance DE Lack of phosphatidylethanolamine N-methyltransferase alters plasma VLDL phospholipids and attenuates atherosclerosis in mice Arterioscler Thromb Vasc Biol 2009 29 1349 1355 10.1161/ATVBAHA.109.188672 19520976 · DOI
  101. Vance DE Vance JE Physiological consequences of disruption of mammalian phospholipid biosynthetic genes J Lipid Res 2009 50 Suppl S132 S137 10.1194/jlr.R800048-JLR200 18955728 PMC2674686 · DOI
  102. Jacobs RL Devlin C Tabas I Vance DE Targeted deletion of hepatic CTP:phosphocholine cytidylyltransferase alpha in mice decreases plasma high density and very low density lipoproteins J Biol Chem 2004 279 47402 47410 10.1074/jbc.M404027200 15331603 · DOI
  103. Jacobs RL Lingrell S Zhao Y Francis GA Vance DE Hepatic CTP:phosphocholine cytidylyltransferase-alpha is a critical predictor of plasma high density lipoprotein and very low density lipoprotein J Biol Chem 2008 283 2147 2155 10.1074/jbc.M706628200 18042552 · DOI · Paper page
  104. Poloumienko A Cote A Quee AT Zhu L Bakovic M Genomic organization and differential splicing of the mouse and human Pcyt2 genes Gene 2004 325 145 155 10.1016/j.gene.2003.10.005 14697519 · DOI
  105. Fullerton MD Hakimuddin F Bonen A Bakovic M The development of a metabolic disease phenotype in CTP:phosphoethanolamine cytidylyltransferase-deficient mice J Biol Chem 2009 284 25704 25713 10.1074/jbc.M109.023846 19625253 PMC2757972 · DOI
  106. Li Z Agellon LB Allen TM Umeda M Jewell L Mason A Vance DE The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis Cell Metab 2006 3 321 331 10.1016/j.cmet.2006.03.007 16679290 · DOI
  107. Gusarova V Brodsky JL Fisher EA Apolipoprotein B100 exit from the endoplasmic reticulum (ER) is COPII-dependent, and its lipidation to very low density lipoprotein occurs post-ER J Biol Chem 2003 278 48051 48058 10.1074/jbc.M306898200 12960170 · DOI
  108. Jones B Jones EL Bonney SA Patel HN Mensenkamp AR Eichenbaum-Voline S Rudling M Myrdal U Annesi G Naik S Mutations in a Sar1 GTPase of COPII vesicles are associated with lipid absorption disorders Nat Genet 2003 34 29 31 10.1038/ng1145 12692552 · DOI
  109. Asp L Magnusson B Rutberg M Li L Boren J Olofsson SO Role of ADP ribosylation factor 1 in the assembly and secretion of ApoB-100-containing lipoproteins Arterioscler Thromb Vasc Biol 2005 25 566 570 10.1161/01.ATV.0000154135.21689.47 15618550 · DOI
  110. Asp L Claesson C Boren J Olofsson SO ADP-ribosylation factor 1 and its activation of phospholipase D are important for the assembly of very low density lipoproteins J Biol Chem 2000 275 26285 26292 10.1074/jbc.M003520200 10843997 · DOI
  111. Rustaeus S Lindberg K Boren J Olofsson SO Brefeldin A reversibly inhibits the assembly of apoB containing lipoproteins in McA-RH7777 cells J Biol Chem 1995 270 28879 28886 10.1074/jbc.270.48.28879 7499415 · DOI
  112. Magnusson B Asp L Bostrom P Ruiz M Stillemark-Billton P Linden D Boren J Olofsson SO Adipocyte differentiation-related protein promotes fatty acid storage in cytosolic triglycerides and inhibits secretion of very low-density lipoproteins Arterioscler Thromb Vasc Biol 2006 26 1566 1571 10.1161/01.ATV.0000223345.11820.da 16627799 · DOI
  113. Ye J Li JZ Liu Y Li X Yang T Ma X Li Q Yao Z Li P Cideb, an ER- and lipid droplet-associated protein, mediates VLDL lipidation and maturation by interacting with apolipoprotein B Cell Metab 2009 9 177 190 10.1016/j.cmet.2008.12.013 19187774 · DOI
  114. Zhou Z Yon TS Chen Z Guo K Ng CP Ponniah S Lin SC Hong W Li P Cidea-deficient mice have lean phenotype and are resistant to obesity Nat Genet 2003 35 49 56 10.1038/ng1225 12910269 · DOI
  115. Kuipers F Jong MC Lin Y Eck M Havinga R Bloks V Verkade HJ Hofker MH Moshage H Berkel TJ Impaired secretion of very low density lipoprotein-triglycerides by apolipoprotein E- deficient mouse hepatocytes J Clin Invest 1997 100 2915 2922 10.1172/JCI119841 9389759 PMC508499 · DOI
  116. Mensenkamp AR Jong MC van GH Van Luyn MJ Bloks V Havinga R Voshol PJ Hofker MH van Dijk KW Havekes LM Apolipoprotein E participates in the regulation of very low density lipoprotein-triglyceride secretion by the liver J Biol Chem 1999 274 35711 35718 10.1074/jbc.274.50.35711 10585451 · DOI
  117. Maugeais C Tietge UJ Tsukamoto K Glick JM Rader DJ Hepatic apolipoprotein E expression promotes very low density lipoprotein-apolipoprotein B production in vivo in mice J Lipid Res 2000 41 1673 1679 11013310
  118. Huang Y Liu XQ Rall SC Jr Taylor JM von EA Assmann G Mahley RW Overexpression and accumulation of apolipoprotein E as a cause of hypertriglyceridemia J Biol Chem 1998 273 26388 26393 10.1074/jbc.273.41.26388 9756870 · DOI · Paper page
  119. Gusarova V Seo J Sullivan ML Watkins SC Brodsky JL Fisher EA Golgi-associated maturation of very low density lipoproteins involves conformational changes in apolipoprotein B, but is not dependent on apolipoprotein E J Biol Chem 2007 282 19453 19462 10.1074/jbc.M700475200 17500069 · DOI
  120. Gangabadage CS Zdunek J Tessari M Nilsson S Olivecrona G Wijmenga SS Structure and dynamics of human apolipoprotein CIII J Biol Chem 2008 283 17416 17427 10.1074/jbc.M800756200 18408013 · DOI
  121. Sundaram M Zhong S Bou Khalil M Zhou H Jiang ZG Zhao Y Iqbal J Hussain MM Figeys D Wang Y Functional analysis of the missense APOC3 mutation Ala23Thr associated with human hypotriglyceridemia J Lipid Res 2010 in press PMC3035516 20097930
  122. Liu H Labeur C Xu CF Ferrell R Lins L Brasseur R Rosseneu M Weiss KM Humphries SE Talmud PJ Characterization of the lipid-binding properties and lipoprotein lipase inhibition of a novel apolipoprotein C-III variant Ala23Thr J Lipid Res 2000 41 1760 1771 11060345
  123. Pennacchio LA Olivier M Hubacek JA Cohen JC Cox DR Fruchart JC Krauss RM Rubin EM An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing Science 2001 294 169 173 10.1126/science.1064852 11588264 · DOI · Paper page
  124. van Dijk KW Rensen PC Voshol PJ Havekes LM The role and mode of action of apolipoproteins CIII and AV: synergistic actors in triglyceride metabolism? Curr Opin Lipidol 2004 15 239 246 10.1097/00041433-200406000-00002 15166778 · DOI · Paper page
  125. Schaap FG Rensen PC Voshol PJ Vrins C van d V Chamuleau RA Havekes LM Groen AK van Dijk KW ApoAV reduces plasma triglycerides by inhibiting very low density lipoprotein-triglyceride (VLDL-TG) production and stimulating lipoprotein lipase-mediated VLDL-TG hydrolysis J Biol Chem 2004 279 27941 27947 10.1074/jbc.M403240200 15090553 · DOI
  126. Shu X Ryan RO Forte TM Intracellular lipid droplet targeting by apolipoprotein A-V requires the carboxyl-terminal segment J Lipid Res 2008 49 1670 1676 10.1194/jlr.M800111-JLR200 18450648 PMC2444012 · DOI
  127. Twisk J Gillian-Daniel DL Tebon A Wang L Barrett PH Attie AD The role of the LDL receptor in apolipoprotein B secretion J Clin Invest 2000 105 521 532 10.1172/JCI8623 10683382 PMC289165 · DOI
  128. James RW Martin B Pometta D Fruchart JC Duriez P Puchois P Farriaux JP Tacquet A Demant T Clegg RJ Apolipoprotein B metabolism in homozygous familial hypercholesterolemia J Lipid Res 1989 30 159 169 2715722
  129. Teusink B Mensenkamp AR van der BH Kuipers F van Dijk KW Havekes LM Stimulation of the in vivo production of very low density lipoproteins by apolipoprotein E is independent of the presence of the low density lipoprotein receptor J Biol Chem 2001 276 40693 40697 10.1074/jbc.M106396200 11546779 · DOI
  130. Williams KJ Brocia RW Fisher EA The unstirred water layer as a site of control of apolipoprotein B secretion J Biol Chem 1990 265 16741 16744 2170353
  131. Jiang XC Qin S Qiao C Kawano K Lin M Skold A Xiao X Tall AR Apolipoprotein B secretion and atherosclerosis are decreased in mice with phospholipid-transfer protein deficiency Nat Med 2001 7 847 852 10.1038/89977 11433351 · DOI · Paper page
  132. Blasiole DA Oler AT Attie AD Regulation of ApoB secretion by the low density lipoprotein receptor requires exit from the endoplasmic reticulum and interaction with ApoE or ApoB J Biol Chem 2008 283 11374 11381 10.1074/jbc.M710457200 18272520 PMC2431081 · DOI · Paper page
  133. Seidah NG Benjannet S Wickham L Marcinkiewicz J Jasmin SB Stifani S Basak A Prat A Chretien M The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation Proc Natl Acad Sci USA 2003 100 928 933 10.1073/pnas.0335507100 12552133 PMC298703 · DOI · Paper page
  134. Maxwell KN Breslow JL Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotype Proc Natl Acad Sci USA 2004 101 7100 7105 10.1073/pnas.0402133101 15118091 PMC406472 · DOI · Paper page
  135. Sun XM Eden ER Tosi I Neuwirth CK Wile D Naoumova RP Soutar AK Evidence for effect of mutant PCSK9 on apolipoprotein B secretion as the cause of unusually severe dominant hypercholesterolaemia Hum Mol Genet 2005 14 1161 1169 10.1093/hmg/ddi128 15772090 · DOI
  136. Rashid S Curtis DE Garuti R Anderson NN Bashmakov Y Ho YK Hammer RE Moon YA Horton JD Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9 Proc Natl Acad Sci USA 2005 102 5374 5379 10.1073/pnas.0501652102 15805190 PMC556275 · DOI · Paper page
  137. Clee SM Kastelein JJ van DM Marcil M Roomp K Zwarts KY Collins JA Roelants R Tamasawa N Stulc T Age and residual cholesterol efflux affect HDL cholesterol levels and coronary artery disease in ABCA1 heterozygotes J Clin Invest 2000 106 1263 1270 10.1172/JCI10727 11086027 PMC381437 · DOI
  138. Chung S Gebre AK Seo J Shelness GS Parks JS A novel role for ABCA1-generated large pre-beta migrating nascent HDL in the regulation of hepatic VLDL triglyceride secretion J Lipid Res 2010 51 729 742 10.1194/jlr.M900083 20215580 PMC2842152 · DOI
  139. Phung TL Roncone A Jensen KL Sparks CE Sparks JD Phosphoinositide 3-kinase activity is necessary for insulin-dependent inhibition of apolipoprotein B secretion by rat hepatocytes and localizes to the endoplasmic reticulum J Biol Chem 1997 272 30693 30702 10.1074/jbc.272.49.30693 9388205 · DOI
  140. Wiersma H Nijstad N Gautier T Iqbal J Kuipers F Hussain MM Tietge UJ Scavenger receptor BI facilitates hepatic very low density lipoprotein production in mice J Lipid Res 2010 51 544 553 10.1194/jlr.M000844 19723664 PMC2817584 · DOI
  141. Meshkani R Adeli K Hepatic insulin resistance, metabolic syndrome and cardiovascular disease Clin Biochem 2009 42 1331 1346 10.1016/j.clinbiochem.2009.05.018 19501581 · DOI
  142. Taghibiglou C Carpentier A Van Iderstine SC Chen B Rudy D Aiton A Lewis GF Adeli K Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance. Evidence for enhanced lipoprotein assembly, reduced intracellular ApoB degradation, and increased microsomal triglyceride transfer protein in a fructose-fed hamster model J Biol Chem 2000 275 8416 8425 10.1074/jbc.275.12.8416 10722675 · DOI
  143. Tsai J Zhang R Qiu W Su Q Naples M Adeli K Inflammatory NF-kappaB activation promotes hepatic apolipoprotein B100 secretion: evidence for a link between hepatic inflammation and lipoprotein production Am J Physiol Gastrointest Liver Physiol 2009 296 G1287 G1298 10.1152/ajpgi.90540.2008 19342510 · DOI
  144. Wiegman CH Bandsma RH Ouwens M Sluijs FH van der Havinga R Boer T Reijngoud DJ Romijn JA Kuipers F Hepatic VLDL production in ob/ob mice is not stimulated by massive de novo lipogenesis but is less sensitive to the suppressive effects of insulin Diabetes 2003 52 1081 1089 10.2337/diabetes.52.5.1081 12716736 · DOI
  145. Li X Grundy SM Patel SB Obesity in db and ob animals leads to impaired hepatic very low density lipoprotein secretion and differential secretion of apolipoprotein B-48 and B-100 J Lipid Res 1997 38 1277 1288 9254055
  146. MacLean PS Bower JF Vadlamudi S Osborne JN Bradfield JF Burden HW Bensch WH Kauffman RF Barakat HA Cholesteryl ester transfer protein expression prevents diet-induced atherosclerotic lesions in male db/db mice Arterioscler Thromb Vasc Biol 2003 23 1412 1415 10.1161/01.ATV.0000080687.94313.67 12791674 · DOI
  147. Coenen KR Gruen ML Hasty AH Obesity causes very low density lipoprotein clearance defects in low-density lipoprotein receptor-deficient mice J Nutr Biochem 2007 18 727 735 10.1016/j.jnutbio.2006.12.010 17418556 · DOI
  148. Pickens MK Yan JS Ng RK Ogata H Grenert JP Beysen C Turner SM Maher JJ Dietary sucrose is essential to the development of liver injury in the MCD model of steatohepatitis J Lipid Res 2009 50 2072 2082 10.1194/jlr.M900022-JLR200 PMC2739762 19295183 · DOI
  149. Rinella ME Elias MS Smolak RR Fu T Borensztajn J Green RM Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet J Lipid Res 2008 49 1068 1076 10.1194/jlr.M800042-JLR200 18227531 PMC2311450 · DOI
  150. Yao ZM Vance DE The active synthesis of phosphatidylcholine is required for very low density lipoprotein secretion from rat hepatocytes J Biol Chem 1988 263 2998 3004 3343237
  151. Pawar A Botolin D Mangelsdorf DJ Jump DB The role of liver × receptor-alpha in the fatty acid regulation of hepatic gene expression J Biol Chem 2003 278 40736 40743 10.1074/jbc.M307973200 12917410 · DOI
  152. Basciano H Miller A Baker C Naples M Adeli K LXRalpha activation perturbs hepatic insulin signaling and stimulates production of apolipoprotein B-containing lipoproteins Am J Physiol Gastrointest Liver Physiol 2009 297 G323 G332 10.1152/ajpgi.90546.2008 19497957 · DOI
  153. Huang W Dedousis N Bandi A Lopaschuk GD O'Doherty RM Liver triglyceride secretion and lipid oxidative metabolism are rapidly altered by leptin in vivo Endocrinology 2006 147 1480 1487 10.1210/en.2005-0731 16339207 · DOI
  154. Huang W Dedousis N O'Doherty RM Hepatic steatosis and plasma dyslipidemia induced by a high-sucrose diet are corrected by an acute leptin infusion J Appl Physiol 2007 102 2260 2265 10.1152/japplphysiol.01449.2006 17363621 · DOI
  155. Huang W Dedousis N Bhatt BA O'Doherty RM Impaired activation of phosphatidylinositol 3-kinase by leptin is a novel mechanism of hepatic leptin resistance in diet-induced obesity J Biol Chem 2004 279 21695 21700 10.1074/jbc.M401546200 14993225 · DOI
  156. Huang W Metlakunta A Dedousis N Ortmeyer HK Stefanovic-Racic M O'Doherty RM Leptin augments the acute suppressive effects of insulin on hepatic very low-density lipoprotein production in rats Endocrinology 2009 150 2169 2174 10.1210/en.2008-1271 19147673 PMC2671913 · DOI
  157. Chirieac DV Collins HL Cianci J Sparks JD Sparks CE Altered triglyceride-rich lipoprotein production in Zucker diabetic fatty rats Am J Physiol Endocrinol Metab 2004 287 E42 E49 10.1152/ajpendo.00297.2003 14970003 · DOI
  158. Taghibiglou C Carpentier A Van Iderstine SC Chen B Rudy D Aiton A Lewis GF Adeli K Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance. Evidence for enhanced lipoprotein assembly, reduced intracellular ApoB degradation, and increased microsomal triglyceride transfer protein in a fructose-fed hamster model J Biol Chem 2000 275 8416 8425 10.1074/jbc.275.12.8416 10722675 · DOI
  159. Benoist F Grand-Perret T Co-translational degradation of apolipoprotein B100 by the proteasome is prevented by microsomal triglyceride transfer protein. Synchronized translation studies on HepG2 cells treated with an inhibitor of microsomal triglyceride transfer protein J Biol Chem 1997 272 20435 20442 10.1074/jbc.272.33.20435 9252352 · DOI
  160. Fisher EA Zhou M Mitchell DM Wu X Omura S Wang H Goldberg AL Ginsberg HN The degradation of apolipoprotein B100 is mediated by the ubiquitin-proteasome pathway and involves heat shock protein 70 J Biol Chem 1997 272 20427 20434 10.1074/jbc.272.33.20427 9252351 · DOI
  161. Liao W Yeung SC Chan L Proteasome-mediated degradation of apolipoprotein B targets both nascent peptides cotranslationally before translocation and full-length apolipoprotein B after translocation into the endoplasmic reticulum J Biol Chem 1998 273 27225 27230 10.1074/jbc.273.42.27225 9765244 · DOI
  162. Ginsberg HN Role of lipid synthesis, chaperone proteins and proteasomes in the assembly and secretion of apoprotein B-containing lipoproteins from cultured liver cells Clin Exp Pharmacol Physiol 1997 24 A29 A32 10.1111/j.1440-1681.1997.tb03051.x 9143794 · DOI
  163. Ginsberg HN Fisher EA The ever-expanding role of degradation in the regulation of apolipoprotein B metabolism J Lipid Res 2009 50 Suppl S162 S166 10.1194/jlr.R800090-JLR200 19050312 PMC2674708 · DOI · Paper page
  164. Shelness GS Ingram MF Huang XF DeLozier JA Apolipoprotein B in the rough endoplasmic reticulum: translation, translocation and the initiation of lipoprotein assembly J Nutr 1999 129 456S 462S 10064309
  165. Yao Z Tran K McLeod RS Intracellular degradation of newly synthesized apolipoprotein B J Lipid Res 1997 38 1937 1953 9374117
  166. Mortimore GE Miotto G Venerando R Kadowaki M Autophagy Subcell Biochem 1996 27 93 135 8993159
  167. Seglen PO Berg TO Blankson H Fengsrud M Holen I Stromhaug PE Structural aspects of autophagy Adv Exp Med Biol 1996 389 103 111 8860999
  168. Cuervo AM Autophagy: many paths to the same end Mol Cell Biochem 2004 263 55 72 10.1023/B:MCBI.0000041848.57020.57 27520665 · DOI
  169. Ohsaki Y Cheng J Fujita A Tokumoto T Fujimoto T Cytoplasmic lipid droplets are sites of convergence of proteasomal and autophagic degradation of apolipoprotein B Mol Biol Cell 2006 17 2674 2683 10.1091/mbc.E05-07-0659 16597703 PMC1474802 · DOI

Cited by

Sorted by citations

Metadata

Authors
Sundaram, M., & Yao, Z.
Venue
Nutrition & Metabolism
Publisher
Springer Science and Business Media LLC
Published
2010
Volume
7
Issue
1
Pages
35
ISSN
1743-7075
DOI
10.1186/1743-7075-7-35
PMC
PMC2873297
Cited by
154
References
4
Language
en

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review