The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.
A Meta-analysis of the effects of Exercise Training on Left Ventricular Remodeling Following Myocardial Infarction: Start early and go longer for greatest exercise benefits on remodeling
Open accessAbstract
BACKGROUND: The effects of variations in exercise training on left ventricular (LV) remodeling in patients shortly after myocardial infarction (MI) are important but poorly understood. METHODS: Systematic review incorporating meta-analysis using meta-regression. Studies were identified via systematic searches of: OVID MEDLINE (1950 to 2009), Cochrane Central Register of Controlled Trials (1991 to 2009), AMED (1985 to 2009), EMBASE (1988 to 2009), PUBMED (1966 to 2009), SPORT DISCUS (1975 to 2009), SCOPUS (1950 to 2009) and WEB OF SCIENCE (1950 to 2009) using the medical subject headings: myocardial infarction, post myocardial infarction, post infarction, heart attack, ventricular remodeling, ventricular volumes, ejection fraction, left ventricular function, exercise, exercise therapy, kinesiotherapy, exercise training. Reference lists of all identified studies were also manually searched for further relevant studies. Studies selected were randomized controlled trials of exercise training interventions reporting ejection fraction (EF) and/or ventricular volumes in patients following recent MI (≤ 3 months) post-MI patients involving control groups. Studies were excluded if they were not randomized, did not have a 'usual-care' control (involving no exercise), evaluated a non-exercise intervention, or did not involve human subjects. Non-English studies were also excluded. RESULTS: After screening of 1029 trials, trials were identified that reported EF (12 trials, n = 647), End Systolic Volumes (ESV) (9 trials, n = 475) and End Diastolic Volumes (EDV) (10 trials, n = 512). Meta-regression identified that changes in EF effect size difference decreased as the time between MI and initiation of the exercise program lengthened, and increased as the duration of the program increased (Q = 25.48, df = 2, p < 0.01, R2 = 0.76). Greater reductions in ESV and EDV (as indicated by effect size decreases) occurred with earlier initiation of exercise training and with longer training durations (ESV: Q = 23.89, df = 2, p < 0.05, R2 = 0.79; EDV: Q = 27.42, df = 2, p < 0.01, R2 = 0.83). Differences remained following sensitivity analysis. Each week that exercise was delayed required an additional month of training to achieve the same level of benefit on LV remodeling. CONCLUSIONS: Exercise training has beneficial effects on LV remodeling in clinically stable post-MI patients with greatest benefits occurring when training starts earlier following MI (from one week) and lasts longer than 3 months.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Figures
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“A 2011 meta-analysis concludes that exercise training has greatest beneficial effects on left ventricular remodeling in clinically stable post-MI patients when training starts one week following the MI (227).”
From Lack of Exercise Is a Major Cause of Chronic Diseases (2012) · cites this paper as [227]
In the citing paper
“A previous meta-analysis 162 found that exercise training following MI can improve LV remodelling, notably by reducing LV end-systolic volume (LVESV)-a strong predictor of mortality after MI-with these benefits maximized if exercise implementation starts early (∼1 week) after the event.”
From Exercise benefits in cardiovascular diseases: From mechanisms to clinical implementation (2023) · cites this paper as [162]
In the citing paper
“A previous meta-analysis 162 found that exercise training following MI can improve LV remodelling, notably by reducing LV end-systolic volume (LVESV)-a strong predictor of mortality after MI-with these benefits maximized if exercise implementation starts early (∼1 week) after the event.”
From Exercise benefits in cardiovascular diseases: From mechanisms to clinical implementation (2023) · cites this paper as [162]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Assessing the quality of reports of randomized clinical trials: Is blinding necessary?
Jadad, A. R., Moore, R. A., Carroll, D., Jenkinson, C., Reynolds, D. J. M., Gavaghan, D. J., & McQuay, H. J. (1996) · Controlled Clinical Trials · doi:10.1016/0197-2456(95)00134-4 · Cited by 17,582
(2000) · Cited by 9,198
White, H. D., Norris, R. M., Brown, M. A., Brandt, P. W., Whitlock, R. M. L., & Wild, C. J. (1987) · Circulation · doi:10.1161/01.cir.76.1.44 · Cited by 2,348
Taylor, R. S., Brown, A., Ebrahim, S., Jolliffe, J., Noorani, H., Rees, K., Skidmore, B., Stone, J. A., Thompson, D. R., & Oldridge, N. (2004) · The American Journal of Medicine · doi:10.1016/j.amjmed.2004.01.009 · Cited by 2,239
An overview of randomized trials of rehabilitation with exercise after myocardial infarction.
O'Connor, G. T., Buring, J. E., Yusuf, S., Goldhaber, S. Z., Olmstead, E. M., Paffenbarger, R. S., & Hennekens, C. H. (1989) · Circulation · doi:10.1161/01.cir.80.2.234 · Cited by 1,414
Uncertainty in heterogeneity estimates in meta-analyses
Ioannidis, J. P. A., Patsopoulos, N. A., & Evangelou, E. (2007) · BMJ · doi:10.1136/bmj.39343.408449.80 · Cited by 1,254
Meta-analysis: secondary prevention programs for patients with coronary artery disease
Clark, A. M., Hartling, L., Vandermeer, B., & McAlister, F. A. (2005) · Annals of Internal Medicine · doi:10.7326/0003-4819-143-9-200511010-00010 · Cited by 979
Kotseva, K., Wood, D., De Backer, G., De Bacquer, D., Pyörälä, K., & Keil, U. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60330-5 · Cited by 833
Oldridge, N. B. (1988) · JAMA · doi:10.1001/jama.1988.03410070073031 · Cited by 800
Chow, C. K., Jolly, S., Rao-Melacini, P., Fox, K. A. A., Anand, S. S., & Yusuf, S. (2010) · Circulation · doi:10.1161/circulationaha.109.891523 · Cited by 719
Research works printed but not linked: 2
- Parker k, Hauer T, Arena R, Lundberg D, Aggarwal S, Goodhart D, D. T: Attendance in an early discharge clinic with symptom limited maximal exercise testing is safe and improves cardiac rehabilitation participation among low-risk stemi patients. Eur J Cardiovasc Prev Rehabil. 2009, 16:
- Clark AM, Hartling L, Vandermeer B, McAlister FA: Secondary prevention program for patients with coronary artery disease: A meta-analysis of randomized control trials. Ann Int Med. 2005, 143: 659-672. · DOI · Paper page
Cited by
Sorted by citations
Lack of Exercise Is a Major Cause of Chronic Diseases
Booth, F. W., Roberts, C. K., & Laye, M. J. (2012) · Comprehensive Physiology · doi:10.1002/cphy.c110025 · Cited by 2,575
2020 ESC guidelines on sports cardiology and exercise in patients with cardiovascular disease
Pelliccia, A., Sharma, S., Gati, S., Bäck, M., Börjesson, M., Caselli, S., Collet, J.-P., Corrado, D., Drezner, J. A., Halle, M., et al. (2021) · European Heart Journal · doi:10.1093/eurheartj/ehaa605 · Cited by 1,958
Ambrosetti, M., Abreu, A., Corrà, U., Davos, C. H., Hansen, D., Frederix, I., Iliou, M. C., Pedretti, R. F. E., Schmid, J.-P., Vigorito, C., et al. (2021) · European Journal of Preventive Cardiology · doi:10.1177/2047487320913379 · Cited by 965
Exercise benefits in cardiovascular disease: beyond attenuation of traditional risk factors
Fiuza-Luces, C., Santos-Lozano, A., Joyner, M., Carrera-Bastos, P., Picazo, O., Zugaza, J. L., Izquierdo, M., Ruilope, L. M., & Lucia, A. (2018) · Nature Reviews Cardiology · doi:10.1038/s41569-018-0065-1 · Cited by 803
Liu, X., Xiao, J., Zhu, H., Wei, X., Platt, C., Damilano, F., Xiao, C., Bezzerides, V. J., Boström, P., Che, L., et al. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2015.02.014 · Cited by 397
Muscle as a paracrine and endocrine organ
Giudice, J., & Taylor, J. M. (2017) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2017.05.005 · Cited by 331
Participation in Cardiac Rehabilitation, Readmissions, and Death After Acute Myocardial Infarction
Dunlay, S. M., Pack, Q. R., Thomas, R. J., Killian, J. M., & Roger, V. L. (2014) · The American Journal of Medicine · doi:10.1016/j.amjmed.2014.02.008 · Cited by 262
Exercise benefits in cardiovascular diseases: From mechanisms to clinical implementation
Valenzuela, P. L., Ruilope, L. M., Santos-Lozano, A., Wilhelm, M., Kränkel, N., Fiuza-Luces, C., & Lucia, A. (2023) · European Heart Journal · doi:10.1093/eurheartj/ehad170 · Cited by 237
Standards and core components for cardiovascular disease prevention and rehabilitation
Cowie, A., Buckley, J., Doherty, P., Furze, G., Hayward, J., Hinton, S., Jones, J. L., Speck, L., Dalal, H. M., & Mills, J. D. (2019) · Heart · doi:10.1136/heartjnl-2018-314206 · Cited by 211
Exercise induces new cardiomyocyte generation in the adult mammalian heart
Vujić, A., Lerchenmüller, C., Wu, T., Guillermier, C., Rabolli, C. P., Gonzalez, E., Senyo, S. E., Liu, X., Guerquin‐Kern, J., Steinhauser, M. L., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-04083-1 · Cited by 185
Buckley, J., Furze, G., Doherty, P., Speck, L., Connolly, S. B., Hinton, S., Jones, J. L., & BACPR, O. B. O. (2013) · Heart · doi:10.1136/heartjnl-2012-303460 · Cited by 180
Regression of cardiac hypertrophy in health and disease: mechanisms and therapeutic potential
Martin, T. G., Juarros, M. A., & Leinwand, L. A. (2023) · Nature Reviews Cardiology · doi:10.1038/s41569-022-00806-6 · Cited by 182
Clark, A. M. (2012) · Social Science & Medicine · doi:10.1016/j.socscimed.2012.03.035 · Cited by 169
Molecular mechanisms of exercise contributing to tissue regeneration
Chen, J., Zhou, R. J., Ye, F., & Cheng, L. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-01233-2 · Cited by 185
Gielen, S., Laughlin, M. H., O'Conner, C. M., & Duncker, D. J. (2014) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2014.10.001 · Cited by 170
Diretriz Brasileira de Reabilitação Cardiovascular – 2020
de Carvalho, T., Milani, M., Ferraz, A. S., da Silveira, A. D., Herdy, A. H., Hossri, C. A. C., Silva, C. G. D. S. E., de Araújo, C. G. S., Rocco, E. A., Teixeira, J. A. C., et al. (2020) · Arquivos Brasileiros de Cardiologia · doi:10.36660/abc.20200407 · Cited by 206
The potential role of endogenous bacteriophages in controlling invading pathogens
Górski, A., & Weber‐Dąbrowska, B. (2005) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-004-4403-6 · Cited by 163
Cai, M.-X., Shi, X.-C., Chen, T., Tan, Z.-N., Lin, Q.-Q., Du, S.-J., & Tian, Z.-J. (2016) · Life Sciences · doi:10.1016/j.lfs.2016.02.055 · Cited by 101
CITED4 induces physiologic hypertrophy and promotes functional recovery after ischemic injury
Bezzerides, V. J., Platt, C., Lerchenmüller, C., Paruchuri, K., Oh, N. L., Xiao, C., Cao, Y., Mann, N., Spiegelman, B. M., & Rosenzweig, A. (2016) · JCI Insight · doi:10.1172/jci.insight.85904 · Cited by 90
Bäck, M., Cider, Å., Herlitz, J. D., Lundberg, M., & Jansson, B. (2016) · Physiotherapy Theory and Practice · doi:10.1080/09593985.2016.1229828 · Cited by 79
Peixoto, T. C. A., Begot, I., Bolzan, D. W., Machado, L., Reis, M. S., Papa, V., Carvalho, A. C. C., Arena, R., Gomes, W. J., & Guizilini, S. (2015) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2014.11.014 · Cited by 116
Marzolini, S., Blanchard, C. M., Alter, D. A., Grace, S. L., & OH, P. I. (2015) · Circulation Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.115.001751 · Cited by 75
Jia, D., Cai, M., Xi, Y., Du, S., & Tian, Z. (2017) · Life Sciences · doi:10.1016/j.lfs.2017.12.009 · Cited by 65
Advances in Exercise, Fitness, and Performance Genomics in 2015
Sarzynski, M. A., Loos, R. J. F., Lucía, A., Përusse, L., Roth, S. M., Wolfarth, B., Rankinen, T., & Bouchard, C. (2016) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000000982 · Cited by 65
Does the timing of cardiac rehabilitation impact fitness outcomes? An observational analysis
Fell, J., Dale, V., & Doherty, P. (2016) · Open Heart · doi:10.1136/openhrt-2015-000369 · Cited by 62
Blasco‐Peris, C., Fuertes-Kenneally, L., Větrovský, T., Sarabia, J. M., Climent, V. E., & Manresa‐Rocamora, A. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19063492 · Cited by 58
Grace, S. L., Turk-Adawi, K. I., Pio, C. S. D. A., & Alter, D. A. (2016) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2016.07.001 · Cited by 59
Animal Models of Exercise From Rodents to Pythons
Hastings, M. H., Herrera, J. J., Guseh, J. S., Atlason, B. A., Houstis, N. E., Kadir, A. A., Li, H., Sheffield, C., Singh, A. P., Roh, J. D., et al. (2022) · Circulation Research · doi:10.1161/circresaha.122.320247 · Cited by 55
Cai, M., Wang, Q., Liu, Z., Jia, D., Feng, R., & Tian, Z. (2018) · Life Sciences · doi:10.1016/j.lfs.2018.10.015 · Cited by 53
Schwaab, B., Bjarnason‐Wehrens, B., Meng, K., Albus, C., Salzwedel, A., Schmid, J., Benzer, W., Metz, M., Jensen, K., Rauch, B., et al. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10143071 · Cited by 55
2020 ESC Guidelines on Sports Cardiology and Exercise in Patients with Cardiovascular Disease
Pelliccia, A., Sharma, S., Gati, S., Bäck, M., Börjesson, M., Caselli, S., Collet, J., Corrado, D., Drezner, J. A., Halle, M., et al. (2021) · Revista Española de Cardiología (English Edition) · doi:10.1016/j.rec.2021.05.003 · Cited by 54
Tai Chi Chuan improves functional capacity after myocardial infarction: A randomized clinical trial
Nery, R. M., Zanini, M., de Lima, J. B., Bühler, R. P., da Silveira, A. D., & Stein, R. (2015) · American Heart Journal · doi:10.1016/j.ahj.2015.01.017 · Cited by 49
Zhong, W., Fu, C., Xu, L., Sun, X., Wang, S., He, C., & Wei, Q. (2023) · BMC Cardiovascular Disorders · doi:10.1186/s12872-023-03120-2 · Cited by 56
Trachsel, L. D., David, L., Gayda, M., Henri, C., Hayami, D., Thorin‐Trescases, N., Thorin, É., Blain, M., Cossette, M., Lalongé, J., et al. (2019) · Clinical Cardiology · doi:10.1002/clc.23277 · Cited by 52
Kim, C., Sung, J., Lee, J. H., Kim, W., Lee, G. J., Jee, S., Jung, I., Rah, U. W., Kim, B. O., Choi, K. H., et al. (2019) · Korean Circulation Journal · doi:10.4070/kcj.2019.0194 · Cited by 48
Manresa‐Rocamora, A., Ribeiro, F., Sarabia, J. M., Íbias, J., Oliveira, N. L., Vera-García, F. J., & Moya‐Ramón, M. (2020) · Clinical Autonomic Research · doi:10.1007/s10286-020-00687-0 · Cited by 51
Scott, J. M., Lee, J., Herndon, J. E., Michalski, M., Lee, C. P., O’Brien, K. A., SASSO, J. P., Yu, A. F., Rowed, K., Bromberg, J., et al. (2023) · European Heart Journal · doi:10.1093/eurheartj/ehad085 · Cited by 44
Ji, N., Luan, J., Hu, F., Zhao, Y., Lv, B., Wang, W., Xia, M., Zhao, X., & Lao, K. (2018) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2018.6597 · Cited by 43
Bäck, M., Lundberg, M., Cider, Å., Herlitz, J. D., & Jansson, B. (2017) · Journal of Cardiopulmonary Rehabilitation and Prevention · doi:10.1097/hcr.0000000000000265 · Cited by 42
Safety of Early Enrollment into Outpatient Cardiac Rehabilitation After Open Heart Surgery
Pack, Q. R., Dudycha, K. J., Roschen, K. P., Thomas, R. J., & Squires, R. W. (2014) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2014.11.040 · Cited by 42
Zhang, H., & Chang, R. (2019) · PubMed Central · Cited by 41
Benefits of lifelong exercise training on left ventricular function after myocardial infarction
Maessen, M. F. H., Eijsvogels, T. M. H., Stevens, G. G. C. F., van Dijk, A. P. J., & Hopman, M. T. E. (2017) · European Journal of Preventive Cardiology · doi:10.1177/2047487317728765 · Cited by 38
Athlete’s Heart Revisited: Historical, Clinical, and Molecular Perspectives
Hsieh, P. N., Shen, S., Chukwurah, M. I., Churchill, T. W., Stewart, K. M., Chung, E. H., Weiner, R. B., Li, H., & Guseh, J. S. (2025) · Circulation Research · doi:10.1161/circresaha.125.325638 · Cited by 47
Resistance Training After Myocardial Infarction in Rats: Its Role on Cardiac and Autonomic Function
Grans, C. F., Feriani, D. J., Abssamra, M. E. V., Rocha, L. Y., Carrozzi, N. M., Mostarda, C. T., Figueroa, D. M. T., Angelis, K. D., Irigoyen, M. C., & Rodrigues, B. (2014) · Arquivos Brasileiros de Cardiologia · doi:10.5935/abc.20140093 · Cited by 37
Jegier, A., Szalewska, D., Mawlichanów, A., Bednarczyk, T., Eysymontt, Z., Gałaszek, M., Mamcarz, A., Mierzyńska, A., Piotrowicz, E., Piotrowicz, R., et al. (2021) · Kardiologia Polska · doi:10.33963/kp.a2021.0066 · Cited by 40
Effect of Early Enrollment on Outcomes in Cardiac Rehabilitation
Johnson, D., Sacrinty, M. T., Gomadam, P. S., Mehta, H., Brady, M. M., Douglas, C. J., Paladenech, C. C., & Robinson, K. (2014) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2014.09.036 · Cited by 36
Reid, D. W., Yamabayashi, Goodridge, D. M., Chung, Hunt, M. A., Marciniuk, Brooks, Chen, Camp, & Hoens, A. M. (2012) · International Journal of COPD · doi:10.2147/copd.s29750 · Cited by 33
The Effect of Exercise Training on Diastolic and Systolic Function After Acute Myocardial Infarction
Fontes‐Carvalho, R., Azevedo, A. I., Sampaio, F., Teixeira, M., Bettencourt, N., Campos, L., Gonçalves, F. R., Ribeiro, V. G., Azevedo, A., & Leite-Moreira, A. F. (2015) · Medicine · doi:10.1097/md.0000000000001450 · Cited by 32
Leardini-Tristão, M., Borges, J. P., de Freitas, F. S. S., Silvares, R. R., Daliry, A., Tibiriçá, E. V., & Estato, V. (2016) · Brain Research · doi:10.1016/j.brainres.2016.11.030 · Cited by 31
Left ventricular ejection fraction as therapeutic target: is it the ideal marker?
Katsi, V. K., Georgiopoulos, G. A., Laina, A., Koutli, E., Parissis, J., Tsioufis, C. P., Nihoyannopoulos, P., & Tousoulis, D. (2017) · Heart Failure Reviews · doi:10.1007/s10741-017-9624-5 · Cited by 31
Evidence for distinct effects of exercise in different cardiac hypertrophic disorders
Johnson, E. J., Dieter, B. P., & Marsh, S. A. (2015) · Life Sciences · doi:10.1016/j.lfs.2015.01.007 · Cited by 31
Mao, S., Zhang, X., Shao, B., Hu, X., Hu, Y., Li, W., Guo, L., & Zhang, M. (2016) · Cardiovascular Drugs and Therapy · doi:10.1007/s10557-016-6660-7 · Cited by 30
Clinical Practice Guideline for Cardiac Rehabilitation in Korea
Kim, C., Sung, J., Lee, J. H., Kim, W., Lee, G. J., Jee, S., Jung, I., Rah, U. W., Kim, B. O., Choi, K. H., et al. (2019) · Annals of Rehabilitation Medicine · doi:10.5535/arm.2019.43.3.355 · Cited by 29
Hauer, K. A., Ullrich, P., Dutzi, I., Beurskens, R., Kern, S., Bauer, J. M., & Schwenk, M. (2017) · Gerontology · doi:10.1159/000478263 · Cited by 29
Naderi, N., Hemmatinafar, M., Gaeini, A. A., Bahramian, A., Afousi, A. G., Kordi, M. R., Darbandi-Azar, A., Karimzade, F., Mohebbi, H., & Barati, M. (2019) · Life Sciences · doi:10.1016/j.lfs.2019.02.045 · Cited by 29
D’Andrea, A., Sperlongano, S., Pacileo, M., Venturini, E., Iannuzzo, G., Gentile, M., Sperlongano, R., Vitale, G., Maglione, M., Cice, G., et al. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9103131 · Cited by 29
Sibilitz, K. L., Berg, S. K., Hansen, T. B., Risom, S. S., Rasmussen, T. B., Hassager, C., Køber, L., Steinbr�chel, D. A., Gluud, C. N., Winkel, P., et al. (2013) · Trials · doi:10.1186/1745-6215-14-104 · Cited by 29
Ventricular and autonomic benefits of exercise training persist after detraining in infarcted rats
Barboza, C. D. A., Rocha, L. Y., Mostarda, C. T., Figueroa, D. A., Caperuto, É. C., Angelis, K. D., Irigoyen, M. C., & Rodrigues, B. (2012) · European Journal of Applied Physiology · doi:10.1007/s00421-012-2533-3 · Cited by 27
Mao, S., Zhang, X., Chen, M., Wang, C., Chen, Q., Guo, L., Zhang, M., & Hinek, A. (2020) · Cardiovascular Drugs and Therapy · doi:10.1007/s10557-020-07047-0 · Cited by 27
Pelliccia, A., Sharma, S., Gati, S., Bäck, M., Börjesson, M., Caselli, S., Collet, J., Corrado, D., Drezner, J. A., Halle, M., et al. (2021) · Revista Española de Cardiología · doi:10.1016/j.recesp.2020.11.026 · Cited by 35
PI3K inhibitors as novel cancer therapies: implications for cardiovascular medicine.
McLean, B. A., Zhabyeyev, P., Pituskin, E., Paterson, I., Haykowsky, M., & Oudit, G. Y. (2013) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2013.02.005 · Cited by 28
The association between intradialytic exercise and hospital usage among hemodialysis patients
Parker, K., Zhang, X., Lewin, A. M., & MacRae, J. M. (2014) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2014-0326 · Cited by 26
Early rehabilitation after acute myocardial infarction: A nationwide inpatient database study
Nakamura, K., Ohbe, H., Uda, K., Fushimi, K., & Yasunaga, H. (2021) · Journal of Cardiology · doi:10.1016/j.jjcc.2021.06.004 · Cited by 30
Current role and future perspectives of cardiac rehabilitation in coronary heart disease
Vilela, E., Ladeiras‐Lopes, R., Joao, A., Braga, J., Torres, S., Viamonte, S., Ribeiro, J., Teixeira, M., Nunes, J. P. L., & Fontes‐Carvalho, R. (2021) · World Journal of Cardiology · doi:10.4330/wjc.v13.i12.695 · Cited by 29
Ohbe, H., Nakamura, K., Uda, K., Matsui, H., & Yasunaga, H. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10040618 · Cited by 24
Heyning, C. M. V. D., Maeyer, C. D., Pattyn, N., Beckers, P. J., Cornelissen, V., Goetschalckx, K., Possemiers, N. M., Craenenbroeck, E. M. V., Voigt, J., Vanhees, L., et al. (2018) · International Journal of Cardiology · doi:10.1016/j.ijcard.2017.11.053 · Cited by 24
Chaparro, C. G. A. P., Zech, P. A., Schuch, F. B., Wolfarth, B., Rapp, M. A., & Heißel, A. (2018) · PLoS ONE · doi:10.1371/journal.pone.0203384 · Cited by 24
Buckley, J. (2021) · Disability and Rehabilitation · doi:10.1080/09638288.2021.1921062 · Cited by 26
Eser, P., Trachsel, L. D., Marcin, T., Herzig, D., Freiburghaus, I., de Marchi, S. F., Zimmermann, A. J., Schmid, J., & Wilhelm, M. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.869501 · Cited by 27
Trachsel, L. D., Boidin, M., Henri, C., Fortier, A., Lalongé, J., Juneau, M., Nigam, A., & Gayda, M. (2020) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2020-0650 · Cited by 21
Mansilla-Chacón, M., Gómez‐Urquiza, J. L., Martos-Cabrera, M. B., Albendín‐García, L., Romero‐Béjar, J. L., la Fuente, G. A. C., & Suleiman‐Martos, N. (2021) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd8120166 · Cited by 26
Exercise: The ultimate treatment to all ailments?
Kasiakogias, A., & Sharma, S. (2020) · Clinical Cardiology · doi:10.1002/clc.23369 · Cited by 22
Hellmark, M., & Bäck, M. (2017) · European Journal of Cardiovascular Nursing · doi:10.1177/1474515117743978 · Cited by 19
Time-to-Referral, Use, and Efficacy of Cardiac Rehabilitation After Heart Transplantation
Marzolini, S., Grace, S. L., Brooks, D., Corbett, D., Mathur, S., Bertelink, R., Skeffington, V., Alter, D. A., & OH, P. I. (2014) · Transplantation · doi:10.1097/tp.0000000000000361 · Cited by 19
McGregor, G., Stöhr, E. J., Oxborough, D., Kimani, P., & Shave, R. (2018) · Annals of Physical and Rehabilitation Medicine · doi:10.1016/j.rehab.2018.01.003 · Cited by 19
MYERS, J. N., Brawner, C. A., Haykowsky, M. J., & Taylor, R. S. (2014) · Heart Failure Clinics · doi:10.1016/j.hfc.2014.08.012 · Cited by 18
Matos-Garcia, B. C., Rocco, I. S., Maiorano, L. D., Peixoto, T. C. A., Moreira, R. S. L., Carvalho, A. C. C., Catai, A. M., Arena, R. A., Gomes, W. J., & Guizilini, S. (2016) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2016.12.004 · Cited by 18
Marcos‐Garcés, V., Bertolín‐Boronat, C., Merenciano-Gonzalez, H., Mas, M. L. M., Alberola, J. I. C., López, L., Rubio, A. P., Pérez-Solé, N., Ríos‐Navarro, C., de Dios, E., et al. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262210964 · Cited by 20
Alhumaid, W., Small, S. D., Kirkham, A. A., Becher, H. H., Pituskin, E., Prado, C. M. M., Thompson, R. B., Haykowsky, M. J., & Paterson, D. I. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.753652 · Cited by 22
Irisin is an Effector Molecule in Exercise Rehabilitation Following Myocardial Infarction (Review)
Qin, S., Tian, Z., Boidin, M., Buckley, B. J. R., Thijssen, D. H. J., & Lip, G. Y. H. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.935772 · Cited by 17
Physical Activity in the Management of Patients with Coronary Artery Disease
Backshall, J., Ford, G. A., Bawamia, B., Quinn, L., Trenell, M. I., & Kunadian, V. (2014) · Cardiology in Review · doi:10.1097/crd.0000000000000032 · Cited by 19
Cai, Z., Lee, Y.-K., Lau, Y., Ho, J. C.-Y., Lai, W., Wong, N. L. Y., Huang, D., Hai, J. J., Ng, K., Tse, H., et al. (2019) · International Journal of Cardiology · doi:10.1016/j.ijcard.2019.09.058 · Cited by 17
van Deel, E. D., Octavia, Y., de Waard, M. C., de Boer, M., & Duncker, D. J. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19071968 · Cited by 17
Shah, Z. A., Jamal, Q. M., Ullah, N., Ahmad, T., & Ahmed, M. (2022) · Cureus · doi:10.7759/cureus.26684 · Cited by 18
Bigot, M., Guy, J. M., Monpère, C., Solal, A. C., Pavy, B., Iliou, M. C., Bosser, G., Corone, S., Douard, H., Farrokhi, T., et al. (2024) · Archives of cardiovascular diseases · doi:10.1016/j.acvd.2024.05.119 · Cited by 16
Exercise training in adverse cardiac remodeling
Duncker, D. J., van Deel, E. D., de Waard, M. C., de Boer, M., Merkus, D., & van der Velden, J. (2014) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-014-1464-8 · Cited by 16
Exercise Training Post-MI Favorably Modifies Heart Extracellular Matrix in the Rat
Yengo, C. M., Zimmerman, S., McCormick, R. J., & Thomas, D. P. (2012) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e318244bc8a · Cited by 16
Teixeira, R. B., Zimmer, A., de Castro, A. L., Seolin, B. G. D. L., Türck, P., Siqueira, R., Belló‐Klein, A., Singal, P. K., & Araújo, A. S. D. R. (2017) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2017.09.021 · Cited by 16
Grossman, G. B., Sellera, C. A. C., Hossri, C. A. C., Carreira, L. C. T. F., Avanza, A. C., de Albuquerque, P. F., Milani, M., Mastrocola, L. E., Ritt, L. E. F., de Freitas, O. G. A., et al. (2020) · Arquivos Brasileiros de Cardiologia · doi:10.36660/abc.20200797 · Cited by 16
Wang, Y., Chien, C.-W., Xu, Y., & Tung, T.-H. (2021) · Healthcare · doi:10.3390/healthcare9060774 · Cited by 15
Acute myocardial infarction: ‘telomerasing’ for cardioprotection
Sanchis-Gomar, F., & Lucia, A. (2015) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2015.02.001 · Cited by 15
Ma, J., Tai, Y., Fan, M., & Wang, Z. (2021) · International Journal of General Medicine · doi:10.2147/ijgm.s326725 · Cited by 14
Shorter Wait Times to Cardiac Rehabilitation Associated With Greater Exercise Capacity Improvements
Candelaria, D., Zecchin, R. P., Ferry, C., Ladak, L. A., Randall, S., & Gallagher, R. D. (2020) · Journal of Cardiopulmonary Rehabilitation and Prevention · doi:10.1097/hcr.0000000000000548 · Cited by 13
Fontes‐Carvalho, R., Sampaio, F., Teixeira, M., Gama, V., & Leite-Moreira, A. F. (2015) · Trials · doi:10.1186/s13063-015-0612-6 · Cited by 13
Kim, C., Choi, H. E., & Lim, Y.-J. (2016) · Annals of Rehabilitation Medicine · doi:10.5535/arm.2016.40.4.647 · Cited by 13
Exercise Prescription in Cardiac Rehabilitation
(2019) · Case Medical Research · doi:10.31525/ct1-nct03925493 · Cited by 12
Overexpressing FSTL1 for heart repair
Sanchis-Gomar, F., Perez-Quilis, C., & Lucia, A. (2016) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2016.03.003 · Cited by 12
2026 ESC Guidelines on cardiac rehabilitation
Bäck, M., Wilhelm, M., Marcin, T., Machado, F. V. C., Sandberg, A., Buccheri, S., Conde, A. C., Czapla, M., Rosa, S. D., Gibson, I., et al. (2026) · European Heart Journal · doi:10.1093/eurheartj/ehag099 · Cited by 27
Shi, X., Chen, X., Qiu, X., Luo, W., Luo, X., Liu, H., Geng, Q., Ma, H., Xue, L., & Guo, L. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.860071 · Cited by 12
Liu, S., Meng, X., Li, G., Gokulnath, P., Wang, J., & Xiao, J. (2022) · Reviews in Cardiovascular Medicine · doi:10.31083/j.rcm2304148 · Cited by 13
Metadata
- Authors
- Haykowsky, M., Scott, J., Esch, B., Schopflocher, D., Myers, J., Paterson, I., Warburton, D., Jones, L., & Clark, A. M.
- Affiliations
- University of Alberta (CA)
- University of British Columbia (CA)
- VA Palo Alto Health Care System (US)
- Duke Medical Center (US)
- Corresponding author
- Haykowsky, Mark
- Venue
- Trials
- Published
- 2011-04-04
- Volume
- 12
- Issue
- 1
- Pages
- 92-92
- ISSN
- 1745-6215 (ISSN-L)
- PMC
- PMC3083361
- OpenAlex
- W2132363115
- Cited by
- 228
- References
- 40
- Citations by year
- 2026: 7 · 2025: 10 · 2024: 23 · 2023: 17 · 2022: 18 · 2021: 22 · 2020: 17 · 2019: 18 · 2018: 15 · 2017: 13 · 2016: 19 · 2015: 12 · 2014: 13 · 2013: 8 · 2012: 14
- FWCI
- 1.93
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Trials (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Research Bank (Australian Catholic University) (submittedVersion)
- cIRcle (University of British Columbia) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- U.S. Department of Veterans Affairs (IK6 RX002477)
- Canadian Institutes of Health Research
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Fibrosis and Remodeling
- Keywords
- exercise training, left ventricular remodeling, myocardial infarction, ejection fraction, end-systolic volume, end-diastolic volume, training duration, cardiac rehabilitation, left ventricular function, ventricular volume
- MeSH terms
- Exercise Therapy, Humans, Myocardial Infarction, Stroke Volume, Time Factors, Ventricular Function, Left, Treatment Outcome, Evidence-Based Medicine, Ventricular Remodeling
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
