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Hepcidin and sports anemia
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“Hepcidin inhibits the activity of ferroportin, a transmembrane protein responsible for exporting Fe from enterocytes, macrophages, and hepatocytes, resulting in decreased Fe availability9 and reduced intestinal Fe absorption10.”
From Impact of a single swimming session on inflammatory response and iron homeostasis in adolescent female athletes during the luteal phase (2025) · cites this paper as [10]
In the citing paper
“According to the literature, iron deficiency may affect 30–50% of endurance athletes and even more than half of young female athletes10,22.”
From Impact of a single swimming session on inflammatory response and iron homeostasis in adolescent female athletes during the luteal phase (2025) · cites this paper as [10]
In the citing paper
“Moreover, hepcidin may not only hamper the availability of iron from monocytes, hepatocytes and enterocytes, through the iron–hepcidin–ferroportin axis [31], but additionally, may impair absorption of iron due to a decrease in duodenal divalent metal transporter 1 (DMT1) levels [51].”
From The Association between Iron and Vitamin D Status in Female Elite Athletes (2018) · cites this paper as [51]
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Nemeth, E., Rivera, S., Gabayan, V., Keller, C., Taudorf, S., Pedersen, B. K., & Ganz, T. (2004) · Journal of Clinical Investigation · doi:10.1172/jci200420945 · Cited by 2,650 · cited 1×
“Hepcidin synthesis was markedly induced by infection and inflammation [51,60], and IL-6 itself is sufficient to induce hepcidin expression during inflammation [61].”
BackgroundHepcidin, a urinary antimicrobial peptide synthesized in the liver
Park, C. H., Valore, E. V., Waring, A. J., & Ganz, T. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m008922200 · Cited by 2,168
Two to tango: Regulation of Mammalian iron metabolism
Hentze, M. W., Muckenthaler, M. U., Galy, B., & Camaschella, C. (2010) · Cell · doi:10.1016/j.cell.2010.06.028 · Cited by 2,120
Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter
Donovan, A., Brownlie, A., Zhou, Y., Shepard, J., Pratt, S. J., Moynihan, J., Paw, B. H., Drejer, A., Barut, B., Zapata, A., et al. (2000) · Nature · doi:10.1038/35001596 · Cited by 1,667
Nicolas, G., Chauvet, C., Viatte, L., Danan, J. L., Bigard, X., Devaux, I., Beaumont, C., Kahn, A., & Vaulont, S. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0215686 · Cited by 1,214
An iron-regulated ferric reductase associated with the absorption of dietary iron
McKie, A. T., Barrow, D., Latunde-Dada, G. O., Rolfs, A., Sager, G., Mudaly, E., Mudaly, M., Richardson, C., Barlow, D., Bomford, A., et al. (2001) · Science · doi:10.1126/science.1057206 · Cited by 1,101
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
Babitt, J. L., Huang, F. W., Wrighting, D. M., Xia, Y., Sidis, Y., Samad, T. A., Campagna, J. A., Chung, R. T., Schneyer, A. L., Woolf, C. J., et al. (2006) · Nature Genetics · doi:10.1038/ng1777 · Cited by 1,026 · cited 1×
“These molecules include HFE (HLA2-linked hemochromatosis gene) [66,67], transferrin receptor 2 (TfR2) [68-70], hemojuvelin (HJV) [71] and bone morphogenetic protein (BMP) [72].”
BackgroundPro‐ and anti‐inflammatory cytokine balance in strenuous exercise in humans
Ostrowski, K., Rohde, T., Asp, S., Schjerling, P., & Pedersen, B. K. (1999) · The Journal of Physiology · doi:10.1111/j.1469-7793.1999.287ad.x · Cited by 1,014
Interleukin-6 induces hepcidin expression through STAT3
Wrighting, D. M., & Andrews, N. C. (2006) · Blood · doi:10.1182/blood-2006-06-027631 · Cited by 983
Mutations in HFE2 cause iron overload in chromosome 1q–linked juvenile hemochromatosis
Papanikolaou, G., Samuels, M. E., Ludwig, E. H., MacDonald, M. L. E., Franchini, P. L., Dubé, M.-P., Andres, L., MacFarlane, J., Sakellaropoulos, N., Politou, M., et al. (2004) · Nature Genetics · doi:10.1038/ng1274 · Cited by 974
Research works printed but not linked: 92
- Stoltzfus RJ: Iron-deficiency anemia: reexamining the nature and magnitude of the public health problem. Summary: implications for research and programs. J Nutr. 2001, 131: 697S-700S. discussion 700S-701S. · DOI
- Janakiraman K, Shenoy S, Sandhu JS: Intravascular haemolysis during prolonged running on asphalt and natural grass in long and middle distance runners. J Sport Sci. 2011, 29: 1287-1292. · DOI
- McInnis MD, Newhouse IJ, von Duvillard SP, Thayer R: The effect of exercise intensity on hematuria in healthy male runners. Eur J Appl Physiol O. 1998, 79: 99-105. · DOI
- DeRuisseau KC, Cheuvront SN, Haymes EM, Sharp RG: Sweat iron and zinc losses during prolonged exercise. Int J Sport Nutr Exe. 2002, 12: 428-437. · DOI
- Babic Z, Papa B, Sikirika-Bosnjakovic M, Prkacin I, Misigoj-Durakovic M, Katicic M: Occult gastrointestinal bleeding in rugby player. J Sport Med Phys Fit. 2001, 41: 399-402.
- Brownlie T, Utermohlen V, Hinton PS, Haas JD: Tissue iron deficiency without anemia impairs adaptation in endurance capacity after aerobic training in previously untrained women. Am J Clin Nutr. 2004, 79: 437-443. · DOI · Paper page
- Ehn L, Carlmark B, Hoglund S: Iron status in athletes involved in intense physical activity. Med Sci Sport Exer. 1980, 12: 61-64.
- Ruckman KS, Sherman AR: Effects of exercise on iron and copper metabolism in rats. J Nutr. 1981, 111: 1593-1601. · DOI
- Gunshin H, Mackenzie B, Berger UV, Gunshin Y, Romero MF, Boron WF, Nussberger S, Gollan JL, Hediger MA: Cloning and characterization of a mammalian proton-coupled metal-ion transporter. Nature. 1997, 388: 482-488. · DOI · Paper page
- Hubert N, Hentze MW: Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: implications for regulation and cellular function. Proc Natl Acad Sci U S A. 2002, 99: 12345-12350. · DOI · Paper page
- Mackenzie B, Takanaga H, Hubert N, Rolfs A, Hediger MA: Functional properties of multiple isoforms of human divalent metal-ion transporter 1 (DMT1). Biochem J. 2007, 403: 59-69. · DOI
- Le Blanc S, Garrick MD, Arredondo M: Heme carrier protein 1 transports heme and is involved in heme-Fe metabolism. Am J Physiol-Cell Ph. 2012, 302: C1780-1785. · DOI
- Gottlieb Y, Truman M, Cohen LA, Leichtmann-Bardoogo Y, Meyron-Holtz EG: Endoplasmic reticulum anchored heme-oxygenase 1 faces the cytosol. Haematologica. 2012, 97: 1489-1493. · DOI
- Munro HN, Linder MC: Ferritin: structure, biosynthesis, and role in iron metabolism. Physiol Rev. 1978, 58: 317-396. · DOI · Paper page
- Yeh KY, Yeh M, Glass J: Interactions between ferroportin and hephaestin in rat enterocytes are reduced after iron ingestion. Gastroenterology. 2011, 141: 292-299. 299 e291. · DOI
- Cherukuri S, Potla R, Sarkar J, Nurko S, Harris ZL, Fox PL: Unexpected role of ceruloplasmin in intestinal iron absorption. Cell Metab. 2005, 2: 309-319. · DOI
- Liu YQ, Chang YZ, Zhao B, Wang HT, Duan XL: Does hepatic hepcidin play an important role in exercise-associated anemia in rats?. Int J Sport Nutr Exe. 2011, 21: 19-26. · DOI
- Shintani N, Kohgo Y, Kato J, Kondo H, Fujikawa K, Miyazaki E, Niitsu Y: Expression and extracellular release of transferrin receptors during peripheral erythroid progenitor cell differentiation in liquid culture. Blood. 1994, 83: 1209-1215. · DOI
- R’Zik S, Loo M, Beguin Y: Reticulocyte transferrin receptor (TfR) expression and contribution to soluble TfR levels. Haematologica. 2001, 86: 244-251.
- Qian ZM, Xiao DS, Tang PL, Yao FY, Liao QK: Increased expression of transferrin receptor on membrane of erythroblasts in strenuously exercised rats. J Appl Physiol. 1999, 87: 523-529. · DOI
- Tian Y, Zhao J, Zhao B, Gao Q, Xu J, Liu D: The ratio of sTfR/ferritin is associated with the expression level of TfR in rat bone marrow cells after endurance exercise. Biol Trace Elem Res. 2012, 147: 261-266. · DOI
- Kaptanoglu B, Turgut G, Genc O, Enli Y, Karabulut I, Zencir M, Turgut S: Effects of acute exercise on the levels of iron, magnesium, and uric acid in liver and spleen tissues. Biol Trace Elem Res. 2003, 91: 173-178. · DOI
- Navas FJ, Cordova A: Iron distribution in different tissues in rats following exercise. Biol Trace Elem Res. 2000, 73: 259-268. · DOI
- Selby GB, Eichner ER: Endurance swimming, intravascular hemolysis, anemia, and iron depletion. New perspective on athlete’s anemia. Am J Med. 1986, 81: 791-794. · DOI · Paper page
- Telford RD, Sly GJ, Hahn AG, Cunningham RB, Bryant C, Smith JA: Footstrike is the major cause of hemolysis during running. J Appl Physiol. 2003, 94: 38-42. · DOI · Paper page
- Kong WNDX, Shi ZH, Chang YZ: Iron metabolism in the mononuclear phagocyte system. Proc Natl Acad Sci U S A. 2008, 18: 1197-1202.
- Magazanik A, Weinstein Y, Dlin RA, Derin M, Schwartzman S, Allalouf D: Iron deficiency caused by 7 weeks of intensive physical exercise. Eur J Appl Physiol O. 1988, 57: 198-202. · DOI
- Merkel D, Huerta M, Grotto I, Blum D, Rachmilewitz E, Fibach E, Epstein Y, Shpilberg O: Incidence of anemia and iron deficiency in strenuously trained adolescents: results of a longitudinal follow-up study. J Adolescent Health. 2009, 45: 286-291. · DOI
- Reinke S, Taylor WR, Duda GN, von Haehling S, Reinke P, Volk HD, Anker SD, Doehner W: Absolute and functional iron deficiency in professional athletes during training and recovery. Int J Cardiol. 2012, 156: 186-191. · DOI
- Roecker L, Meier-Buttermilch R, Brechtel L, Nemeth E, Ganz T: Iron-regulatory protein hepcidin is increased in female athletes after a marathon. Eur J Appl Physiol. 2005, 95: 569-571. · DOI
- Peeling P, Dawson B, Goodman C, Landers G, Wiegerinck ET, Swinkels DW, Trinder D: Effects of exercise on hepcidin response and iron metabolism during recovery. Int J Sport Nutr Exe. 2009, 19: 583-597. · DOI
- Auersperger I, Knap B, Jerin A, Blagus R, Lainscak M, Skitek M, Skof B: The effects of 8 weeks of endurance running on hepcidin concentrations, inflammatory parameters, and iron status in female runners. Int J Sport Nutr Exe. 2012, 22: 55-63. · DOI
- Nemeth E, Tuttle MS, Powelson J, Vaughn MB, Donovan A, Ward DM, Ganz T, Kaplan J: Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science. 2004, 306: 2090-2093. · DOI · Paper page
- Ramey G, Deschemin JC, Durel B, Canonne-Hergaux F, Nicolas G, Vaulont S: Hepcidin targets ferroportin for degradation in hepatocytes. Haematologica. 2010, 95: 501-504. · DOI
- Knutson MD, Oukka M, Koss LM, Aydemir F, Wessling-Resnick M: Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin. Proc Natl Acad Sci U S A. 2005, 102: 1324-1328. · DOI · Paper page
- Yeh KY, Yeh M, Glass J: Hepcidin regulation of ferroportin 1 expression in the liver and intestine of the rat. Am J Physiol-Gastr L. 2004, 286: G385-394.
- Chung B, Chaston T, Marks J, Srai SK, Sharp PA: Hepcidin decreases iron transporter expression in vivo in mouse duodenum and spleen and in vitro in THP-1 macrophages and intestinal Caco-2 cells. J Nutr. 2009, 139: 1457-1462. · DOI
- Mena NP, Esparza A, Tapia V, Valdes P, Nunez MT: Hepcidin inhibits apical iron uptake in intestinal cells. Am J Physiol-Gastr L. 2008, 294: G192-198.
- Liu YQ, Duan XL, Chang YZ, Wang HT, Qian ZM: Molecular analysis of increased iron status in moderately exercised rats. Mol Cell Biochem. 2006, 282: 117-123. · DOI · Paper page
- Troadec MB, Laine F, Daniel V, Rochcongar P, Ropert M, Cabillic F, Perrin M, Morcet J, Loreal O, Olbina G, Westerman M, Nemeth E, Ganz T, Brissot P: Daily regulation of serum and urinary hepcidin is not influenced by submaximal cycling exercise in humans with normal iron metabolism. Eur J Appl Physiol. 2009, 106: 435-443. · DOI
- Nguyen NB, Callaghan KD, Ghio AJ, Haile DJ, Yang F: Hepcidin expression and iron transport in alveolar macrophages. Am J Physiol-Lung C. 2006, 291: L417-425. · DOI · Paper page
- Ramos E, Kautz L, Rodriguez R, Hansen M, Gabayan V, Ginzburg Y, Roth MP, Nemeth E, Ganz T: Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice. Hepatology. 2011, 53: 1333-1341. · DOI
- Kong WN, Chang YZ, Wang SM, Zhai XL, Shang JX, Li LX, Duan XL: Effect of erythropoietin on hepcidin, DMT1 with IRE, and hephaestin gene expression in duodenum of rats. J Gastroenterol. 2008, 43: 136-143. · DOI
- Chaston TB, Matak P, Pourvali K, Srai SK, McKie AT, Sharp PA: Hypoxia inhibits hepcidin expression in HuH7 hepatoma cells via decreased SMAD4 signaling. American journal of physiology Cell physiology. 2011, 300: C888-895. · DOI
- Pedersen BK, Hoffman-Goetz L: Exercise and the immune system: regulation, integration, and adaptation. Physiol Rev. 2000, 80: 1055-1081. · DOI · Paper page
- Pedersen BK, Steensberg A, Schjerling P: Exercise and interleukin-6. Curr Opin Hematol. 2001, 8: 137-141. · DOI · Paper page
- Margeli A, Skenderi K, Tsironi M, Hantzi E, Matalas AL, Vrettou C, Kanavakis E, Chrousos G, Papassotiriou I: Dramatic elevations of interleukin-6 and acute-phase reactants in athletes participating in the ultradistance foot race spartathlon: severe systemic inflammation and lipid and lipoprotein changes in protracted exercise. J Clin Endocr Metab. 2005, 90: 3914-3918. · DOI
- Fischer CP: Interleukin-6 in acute exercise and training: what is the biological relevance?. Exerc Immunol Rev. 2006, 12: 6-33.
- Nemeth E, Valore EV, Territo M, Schiller G, Lichtenstein A, Ganz T: Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein. Blood. 2003, 101: 2461-2463. · DOI · Paper page
- Banzet S, Sanchez H, Chapot R, Bigard X, Vaulont S, Koulmann N: Interleukin-6 contributes to hepcidin mRNA increase in response to exercise. Cytokine. 2012, 58: 158-161. · DOI
- Corradini E, Garuti C, Montosi G, Ventura P, Andriopoulos B, Lin HY, Pietrangelo A, Babitt JL: Bone morphogenetic protein signaling is impaired in an HFE knockout mouse model of hemochromatosis. Gastroenterology. 2009, 137: 1489-1497. · DOI
- Kawabata H, Fleming RE, Gui D, Moon SY, Saitoh T, O’Kelly J, Umehara Y, Wano Y, Said JW, Koeffler HP: Expression of hepcidin is down-regulated in TfR2 mutant mice manifesting a phenotype of hereditary hemochromatosis. Blood. 2005, 105: 376-381. · DOI
- Wallace DF, Summerville L, Crampton EM, Frazer DM, Anderson GJ, Subramaniam VN: Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload. Hepatology. 2009, 50: 1992-2000. · DOI
- Nemeth E, Roetto A, Garozzo G, Ganz T, Camaschella C: Hepcidin is decreased in TFR2 hemochromatosis. Blood. 2005, 105: 1803-1806. · DOI · Paper page
- Niederkofler V, Salie R, Arber S: Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload. J Clin Invest. 2005, 115: 2180-2186. · DOI · Paper page
- Meynard D, Kautz L, Darnaud V, Canonne-Hergaux F, Coppin H, Roth MP: Lack of the bone morphogenetic protein BMP6 induces massive iron overload. Nat Genet. 2009, 41: 478-481. · DOI · Paper page
- Zhang AS: Control of systemic iron homeostasis by the hemojuvelin-hepcidin axis. Adv Nutr. 2010, 1: 38-45. · DOI
- Krantz SB: Erythropoietin. Blood. 1991, 77: 419-434. · DOI · Paper page
- Roecker L, Kowoll R, Fraszl W, Battal K, Brechtel L, Brachmann S, Meier-Buttermilch R, Gunga HC, Stangl A, Kiesewetter H: Observation of serum erythropoietin concentrations in female athletes for up to eight days after a marathon run. Clin Lab. 2006, 52: 511-513.
- Nicolas G, Viatte L, Bennoun M, Beaumont C, Kahn A, Vaulont S: Hepcidin, a new iron regulatory peptide. Blood Cells Mol Dis. 2002, 29: 327-335. · DOI · Paper page
- Pinto JP, Ribeiro S, Pontes H, Thowfeequ S, Tosh D, Carvalho F, Porto G: Erythropoietin mediates hepcidin expression in hepatocytes through EPOR signaling and regulation of C/EBPalpha. Blood. 2008, 111: 5727-5733. · DOI
- Vokurka M, Krijt J, Sulc K, Necas E: Hepcidin mRNA levels in mouse liver respond to inhibition of erythropoiesis. Physiol Res. 2006, 55: 667-674. · DOI · Paper page
- Ramirez JM, Schaad O, Durual S, Cossali D, Docquier M, Beris P, Descombes P, Matthes T: Growth differentiation factor 15 production is necessary for normal erythroid differentiation and is increased in refractory anaemia with ring-sideroblasts. Brit J Haematol. 2009, 144: 251-262. · DOI · Paper page
- Forejtnikovà H, Vieillevoye M, Zermati Y, Lambert M, Pellegrino RM, Guihard S, Gaudry M, Camaschella C, Lacombe C, Roetto A, Mayeux P, Verdier F: Transferrin receptor 2 is a component of the erythropoietin receptor complex and is required for efficient erythropoiesis. Blood. 2010, 116: 5357-5367. · DOI · Paper page
- Tanno T, Bhanu NV, Oneal PA, Goh SH, Staker P, Lee YT, Moroney JW, Reed CH, Luban NL, Wang RH, Eling TE, Childs R, Ganz T, Leitman SF, Fucharoen S, Miller JL: High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin. Nat Med. 2007, 13: 1096-1101. · DOI · Paper page
- Tanno T, Porayette P, Sripichai O, Noh SJ, Byrnes C, Bhupatiraju A, Lee YT, Goodnough JB, Harandi O, Ganz T, Paulson RF, Miller JL: Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells. Blood. 2009, 114: 181-186. · DOI · Paper page
- Casanovas G, Spasic MV, Casu C, Rivella S, Strelau J, Unsicker K, Muckenthaler MU: The murine growth differentiation factor 15 is not essential for systemic iron homeostasis in phlebotomized mice. Haematologica. 2013, 98: 444-447. · DOI
- Son HJ, Kim HJ, Kim JH, Ohno H, Kim CK: Erythropoietin, 2, 3 DPG, oxygen transport capacity, and altitude training in adolescent Alpine skiers. Aviat Space Envir Md. 2012, 83: 50-53. · DOI
- Christoulas K, Karamouzis M, Mandroukas K: “Living high - training low” vs. “living high - training high”: erythropoietic responses and performance of adolescent cross-country skiers. J Sport Med Phys Fit. 2011, 51: 74-81.
- Goetze O, Schmitt J, Spliethoff K, Theurl I, Weiss G, Swinkels DW, Tjalsma H, Maggiorini M, Krayenbuhl P, Rau M, Fruehauf H, Wojtal KA, Müllhaupt B, Fried M, Gassmann M, Lutz T, Geier A: Adaptation of iron transport and metabolism to acute high-altitude hypoxia in mountaineers. Hepatology. 2013, 58: 2153-2162. · DOI
- Lakhal S, Schodel J, Townsend AR, Pugh CW, Ratcliffe PJ, Mole DR: Regulation of type II transmembrane serine proteinase TMPRSS6 by hypoxia-inducible factors: new link between hypoxia signaling and iron homeostasis. J Biol Chem. 2011, 286: 4090-4097. · DOI
- Babitt JL, Huang FW, Xia Y, Sidis Y, Andrews NC, Lin HY: Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance. J Clin Invest. 2007, 117: 1933-1939. · DOI · Paper page
- Ganz T, Olbina G, Girelli D, Nemeth E, Westerman M: Immunoassay for human serum hepcidin. Blood. 2008, 112: 4292-4297. · DOI · Paper page
- Guo W, Bachman E, Li M, Roy CN, Blusztajn J, Wong S, Chan SY, Serra C, Jasuja R, Travison TG, Muckenthaler MU, Nemeth E, Bhasin S: Testosterone administration inhibits hepcidin transcription and is associated with increased iron incorporation into red blood cells. Aging Cell. 2013, 12: 280-291. · DOI · Paper page
- Swinkels DW, Girelli D, Laarakkers C, Kroot J, Campostrini N, Kemna EH, Tjalsma H: Advances in quantitative hepcidin measurements by time-of-flight mass spectrometry. PloS One. 2008, 3: e2706. · DOI
- Kroot JJ, Laarakkers CM, Geurts-Moespot AJ, Grebenchtchikov N, Pickkers P, van Ede AE, Peters HP, van Dongen-Lases E, Wetzels JF, Sweep FC, Tjalsma H, Swinkels DW: Immunochemical and mass-spectrometry-based serum hepcidin assays for iron metabolism disorders. Clin Chem. 2010, 56: 1570-1579. · DOI
- Bansal SS, Abbate V, Bomford A, Halket JM, Macdougall IC, Thein SL, Hider RC: Quantitation of hepcidin in serum using ultra-high-pressure liquid chromatography and a linear ion trap mass spectrometer. Rapid Commun Mass Spectrom. 2010, 24: 1251-1259. · DOI
- Laarakkers CM, Wiegerinck ET, Klaver S, Kolodziejczyk M, Gille H, Hohlbaum AM, Tjalsma H, Swinkels DW: Improved mass spectrometry assay for plasma hepcidin: detection and characterization of a novel hepcidin isoform. PloS One. 2013, 8: e75518. · DOI
- Busbridge M, Griffiths C, Ashby D, Gale D, Jayantha A, Sanwaiya A, Chapman RS: Development of a novel immunoassay for the iron regulatory peptide hepcidin. Brit J Biomed Sci. 2009, 66: 150-157. · DOI
- Schwarz P, Strnad P, von Figura G, Janetzko A, Krayenbuhl P, Adler G, Kulaksiz H: A novel monoclonal antibody immunoassay for the detection of human serum hepcidin. J Gastroenterol. 2011, 46: 648-656. · DOI
- Garza D, Shrier I, Kohl HW, Ford P, Brown M, Matheson GO: The clinical value of serum ferritin tests in endurance athletes. Clin J Sport Med. 1997, 7: 46-53. · DOI
- Mettler S, Zimmermann MB: Iron excess in recreational marathon runners. Eur J Clin Nutr. 2010, 64: 490-494. · DOI
- Cooke KS, Hinkle B, Salimi-Moosavi H, Foltz I, King C, Rathanaswami P, Winters A, Steavenson S, Begley CG, Molineux G, Sasu BJ: A fully-human anti-hepcidin antibody modulates iron metabolism in both mice and non-human primates. Blood. 2013, 122: 3054-3061. · DOI · Paper page
- Gaudard A, Varlet-Marie E, Bressolle F, Audran M: Drugs for increasing oxygen and their potential use in doping: a review. Sports Med. 2003, 33: 187-212. · DOI
- John MJ, Jaison V, Jain K, Kakkar N, Jacob JJ: Erythropoietin use and abuse. Indian J Endocrinol Metabol. 2012, 16: 220-227. · DOI
- Kong WN, Zhao SE, Duan XL, Yang Z, Qian ZM, Chang YZ: Decreased DMT1 and increased ferroportin 1 expression is the mechanisms of reduced iron retention in macrophages by erythropoietin in rats. J Cell Biochem. 2008, 104: 629-641. · DOI
- Piloto N, Teixeira HM, Teixeira-Lemos E, Parada B, Garrido P, Sereno J, Pinto R, Carvalho L, Costa E, Belo L, Santos-Silva A, Teixeira F, Reis F: Erythropoietin promotes deleterious cardiovascular effects and mortality risk in a rat model of chronic sports doping. Cardiovasc Toxicol. 2009, 9: 201-210. · DOI
- Nishimoto N, Kanakura Y, Aozasa K, Johkoh T, Nakamura M, Nakano S, Nakano N, Ikeda Y, Sasaki T, Nishioka K, Hara M, Taguchi H, Kimura Y, Kato Y, Asaoku H, Kumagai S, Kodama F, Nakahara H, Hagihara K, Yoshizaki K, Kishimoto T: Humanized anti-interleukin-6 receptor antibody treatment of multicentric Castleman disease. Blood. 2005, 106: 2627-2632. · DOI · Paper page
- Shin DY, Chung J, Joe Y, Pae HO, Chang KC, Cho GJ, Ryter SW, Chung HT: Pretreatment with CO-releasing molecules suppresses hepcidin expression during inflammation and endoplasmic reticulum stress through inhibition of the STAT3 and CREBH pathways. Blood. 2012, 119: 2523-2532. · DOI
- van de Vosse E, van Agtmael MA: Targets of anticytokine therapy and the risk of infections in humans and mice. Curr Opin Rheumatol. 2007, 19: 626-635. · DOI
- Yu PB, Hong CC, Sachidanandan C, Babitt JL, Deng DY, Hoyng SA, Lin HY, Bloch KD, Peterson RT: Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nat Chem Biol. 2008, 4: 33-41. · DOI · Paper page
- Poli M, Girelli D, Campostrini N, Maccarinelli F, Finazzi D, Luscieti S, Nai A, Arosio P: Heparin: a potent inhibitor of hepcidin expression in vitro and in vivo. Blood. 2011, 117: 997-1004. · DOI · Paper page
Cited by
The Association between Iron and Vitamin D Status in Female Elite Athletes
Malczewska-Lenczowska, J., Sitkowski, D., Surała, O., Orysiak, J., Szczepańska, B., & Witek, K. (2018) · Nutrients · doi:10.3390/nu10020167 · Cited by 76
Mydłowska, M., Kasperska, A., Cichoń-Woźniak, J., Dziewiecka, H., Ostapiuk-Karolczuk, J., & Skarpańska-Stejnborn, A. (2025) · Scientific Reports · doi:10.1038/s41598-025-29551-9 · Cited by 2
Metadata
- Authors
- Kong, W.-N., Gao, G., & Chang, Y.-Z.
- Venue
- Cell & Bioscience
- Published
- 2014-04-14
- Volume
- 4
- Issue
- 1
- ISSN
- 2045-3701
- Cited by
- 54
- References
- 37
- Language
- en
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Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Hepcidin and sports anemia. https://app.cochat.ai/papers/10.1186/2045-3701-4-19
- The paper
- Kong, W.-N., Gao, G., & Chang, Y.-Z. (2014). Hepcidin and sports anemia. Cell & Bioscience. https://doi.org/10.1186/2045-3701-4-19
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.