The hCMEC/D3 cell line as a model of the human blood brain barrier

Blood‐brain barrier‐specific properties of a human adult brain endothelial cell line

Weksler, B. B., Subileau, E.-A., Perrière, N., Charneau, P., Holloway, K. E., Leveque, M., Tricoire-Leignel, H., Nicotra, A., Bourdoulous, S., Turowski, P., et al. (2005) · The FASEB Journal · doi:10.1096/fj.04-3458fje · Cited by 1,325

Wnt/β-catenin signaling controls development of the blood–brain barrier

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Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells

Lippmann, E. S., Azarin, S. M., Kay, J. E., Nessler, R. A., Wilson, H. K., Al-Ahmad, A., Palecek, S. P., & Shusta, E. V. (2012) · Nature Biotechnology · doi:10.1038/nbt.2247 · Cited by 800

Electrical resistance across the blood-brain barrier in anaesthetized rats: a developmental study.

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Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation

Luissint, A.-C., Artus, C., Glacial, F., Ganeshamoorthy, K., & Couraud, P.-O. (2012) · Fluids and Barriers of the CNS · doi:10.1186/2045-8118-9-23 · Cited by 654

ABC transporters, cytochromes P450 and their main transcription factors: expression at the human blood–brain barrier

Dauchy, S., Dutheil, F., Weaver, R. J., Chassoux, F., Daumas‐Duport, C., Couraud, P., Scherrmann, J., de Waziers, I., & Declèves, X. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05720.x · Cited by 361

Development of a three-dimensional, all-human in vitro model of the blood–brain barrier using mono-, co-, and tri-cultivation Transwell models

Hatherell, K. E., Couraud, P., Romero, I. A., Weksler, B. B., & Pilkington, G. J. (2011) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2011.05.012 · Cited by 358

The human brain endothelial cell line hCMEC/D3 as a human blood‐brain barrier model for drug transport studies

Poller, B., Gutmann, H., Krähenbühl, S., Weksler, B. B., Romero, I. A., Couraud, P., Tuffin, G., Drewe, J., & Huwyler, J. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05730.x · Cited by 318

Differential effects of hydrocortisone and TNFα on tight junction proteins in an in vitro model of the human blood–brain barrier

Förster, C. Y., Burek, M., Romero, I. A., Weksler, B. B., Couraud, P., & Drenckhahn, D. (2008) · The Journal of Physiology · doi:10.1113/jphysiol.2007.146852 · Cited by 306

Immortalized Human Brain Endothelial Cells and Flow-Based Vascular Modeling: A Marriage of Convenience for Rational Neurovascular Studies

Cucullo, L., Couraud, P., Weksler, B. B., Romero, I. A., Hossain, M. K., Rapp, E., & Janigro, D. (2007) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/sj.jcbfm.9600525 · Cited by 266

Antiretroviral drugs efavirenz, dolutegravir and bictegravir dysregulate blood-brain barrier integrity and function

Huang, C., Hoque, M. T., & Bendayan, R. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1118580 · Cited by 25

Iron oxide nanoparticles surface coating and cell uptake affect biocompatibility and inflammatory responses of endothelial cells and macrophages

Orlando, A., Colombo, M., Prosperi, D., Gregori, M., Panariti, A., Rivolta, I., Masserini, M., & Cazzaniga, E. (2015) · Journal of Nanoparticle Research · doi:10.1007/s11051-015-3148-5 · Cited by 25

Functional Investigation of Solute Carrier Family 35, Member F2, in Three Cellular Models of the Primate Blood-Brain Barrier

Mochizuki, T., Mizuno, T., Kurosawa, T., Yamaguchi, T., Higuchi, K., Tega, Y., Nozaki, Y., Kawabata, K., Deguchi, Y., & Kusuhara, H. (2020) · Drug Metabolism and Disposition · doi:10.1124/dmd.120.000115 · Cited by 25

Alzheimer's disease‐associated P460L variant of EphA1 dysregulates receptor activity and blood‐brain barrier function

Owens, H., Thorburn, L. E., Walsby, E. J., Moon, O. R., Rizkallah, P. J., Sherwani, S., Tinsley, C. L., Rogers, L., Cerutti, C., Ridley, A. J., et al. (2024) · Alzheimer s & Dementia · doi:10.1002/alz.13603 · Cited by 24

MiR-34a regulates blood–tumor barrier function by targeting protein kinase Cε

Zhao, W., Wang, P., Ma, J., Liu, Y., Li, Z., Li, Z., Wang, Z., Chen, L., & Xue, Y. (2015) · Molecular Biology of the Cell · doi:10.1091/mbc.e14-10-1474 · Cited by 24

Transport of a Prolyl Endopeptidase Inhibitory Peptide across the Blood–Brain Barrier Demonstrated Using the hCMEC/D3 Cell Line Transcytosis Assay

Hayes, M., Moen, L. F., Auty, M. A. E., & Lea, T. (2015) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5b04696 · Cited by 24

Modeling the blood-brain barrier for treatment of central nervous system (CNS) diseases

Rice, O., Surian, A., & Chen, Y. (2022) · Journal of Tissue Engineering · doi:10.1177/20417314221095997 · Cited by 25

Bisdemethoxycurcumin (BDC)-Loaded H-Ferritin-Nanocages Mediate the Regulation of Inflammation in Alzheimer’s Disease Patients

Gagliardi, S., Truffi, M., Tinelli, V., Garofalo, M., Pandini, C., Ramusino, M. C., Perini, G., Costa, A. C., Negri, S., Mazzucchelli, S., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23169237 · Cited by 25

Curcumin and N-Acetylcysteine Nanocarriers Alone or Combined with Deferoxamine Target the Mitochondria and Protect against Neurotoxicity and Oxidative Stress in a Co-Culture Model of Parkinson’s Disease

Mursaleen, L., Chan, S. H. Y., Noble, B., Somavarapu, S., & Zariwala, M. G. (2023) · Antioxidants · doi:10.3390/antiox12010130 · Cited by 23

Histidine-rich protein II nanoparticle delivery of heme iron load drives endothelial inflammation in cerebral malaria

Nguyen, S. T., Du, D., Wychrij, D., Cain, M. D., Wu, Q., Klein, R. S., Russo, I., & Goldberg, D. E. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2306318120 · Cited by 24

Cell-based in vitro models for studying blood–brain barrier (BBB) permeability

Gomes, M. J., Mendes, B. B., Martins, S., & Sarmento, B. F. C. C. (2015) · Elsevier eBooks · doi:10.1016/b978-0-08-100094-6.00011-0 · Cited by 24

Constitutive Androstane Receptor: A Peripheral and a Neurovascular Stress or Environmental Sensor

Oliviero, F., Lukowicz, C., Boussadia, B., Forner-Piquer, I., Pascussi, J., Marchi, N., & Mselli-Lakhal, L. (2020) · Cells · doi:10.3390/cells9112426 · Cited by 25

Cryopreservation of human cerebral microvascular endothelial cells and astrocytes in suspension and monolayers

Marquez‐Curtis, L. A., Bokenfohr, R., McGann, L. E., & Elliott, J. A. W. (2021) · PLoS ONE · doi:10.1371/journal.pone.0249814 · Cited by 24

Customized blood-brain barrier shuttle peptide to increase AAV9 vector crossing the BBB and augment transduction in the brain

Zhang, X., Chai, Z., Lee Dobbins, A., Itano, M. S., Askew, C., Miao, Z., Niu, H., Samulski, R. J., & Li, C. (2022) · Biomaterials · doi:10.1016/j.biomaterials.2021.121340 · Cited by 23

Angiopoietin-like 4 protects against endothelial dysfunction during bacterial sepsis

Ziveri, J., Guennec, L. L., Souza, I. D. S., Barnier, J., Walter, S. M., Diallo, Y., Smail, Y., Seac’h, E. L., Bouzinba-Ségard, H., Faure, C., et al. (2024) · Nature Microbiology · doi:10.1038/s41564-024-01760-4 · Cited by 23

Amyloid beta25‐35 impairs docosahexaenoic acid efflux by down‐regulating fatty acid transport protein 1 (FATP1/SLC27A1) protein expression in human brain capillary endothelial cells

Ochiai, Y., Uchida, Y., Tachikawa, M., Couraud, P., & Terasaki, T. (2019) · Journal of Neurochemistry · doi:10.1111/jnc.14722 · Cited by 23

Identification of Cell-Surface Proteins Endocytosed by Human Brain Microvascular Endothelial Cells In Vitro

Ito, S., Oishi, M., Ogata, S., Uemura, T., Couraud, P., Masuda, T., & Ohtsuki, S. (2020) · Pharmaceutics · doi:10.3390/pharmaceutics12060579 · Cited by 23

Aryl hydrocarbon receptor regulates CYP1B1 but not ABCB1 and ABCG2 in hCMEC/D3 human cerebral microvascular endothelial cells after TCDD exposure

Jacob, A., Potin, S., Chapy, H., Crété, D., Glacial, F., Ganeshamoorthy, K., Couraud, P., Scherrmann, J., & Declèves, X. (2015) · Brain Research · doi:10.1016/j.brainres.2015.03.049 · Cited by 23

Adenosine receptors regulate gap junction coupling of the human cerebral microvascular endothelial cells hCMEC/D3 by Ca2+influx through cyclic nucleotide‐gated channels

Bader, A., Bintig, W., Begandt, D., Klett, A., Siller, I. G., Gregor, C., Schaarschmidt, F., Weksler, B. B., Romero, I. A., Couraud, P., et al. (2017) · The Journal of Physiology · doi:10.1113/jp273150 · Cited by 23

Selective stimulation of the JAK/STAT signaling pathway by silica nanoparticles in human endothelial cells

Siegrist, S., Kettiger, H., Fasler‐Kan, E., & Huwyler, J. (2017) · Toxicology in Vitro · doi:10.1016/j.tiv.2017.05.002 · Cited by 23

The interaction of clozapine loaded nanocapsules with the hCMEC/D3 cells – In vitro model of blood brain barrier

Łukasiewicz, S., Błasiak, E., Szczepanowicz, K., Guzik, K., Bzowska, M., Warszyński, P., & Dziedzicka‐Wasylewska, M. (2017) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2017.07.053 · Cited by 23

Glutamate affects the CYP1B1- and CYP2U1-mediated hydroxylation of arachidonic acid metabolism via astrocytic mGlu5 receptor

Yu, X., Wu, J., Hu, M.-B., Wu, J., Zhu, Q., Yang, Z., Xie, X., Feng, Y., & Yue, J. (2019) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2019.03.001 · Cited by 23

A Microfluidic Human Model of Blood–Brain Barrier Employing Primary Human Astrocytes

Lauranzano, E., Campo, E., Rasile, M., Molteni, R., Pizzocri, M., Passoni, L., Bello, L., Pozzi, D., Pardi, R., Matteoli, M., et al. (2019) · Advanced Biosystems · doi:10.1002/adbi.201800335 · Cited by 23

Co-culture model consisting of human brain microvascular endothelial and peripheral blood mononuclear cells

Strazza, M., Maubert, M. E., Pirrone, V., Wigdahl, B. L., & Nonnemacher, M. R. (2016) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2016.05.016 · Cited by 24

Paracellular tightness and the functional expression of efflux transporters P-gp and BCRP in bEnd3 cells

Yang, S., Jin, H. W., & Zhao, Z. (2018) · Neurological Research · doi:10.1080/01616412.2018.1460701 · Cited by 22

Cell-type specific differences in antiretroviral penetration and the effects of HIV-1 Tat and morphine among primary human brain endothelial cells, astrocytes, pericytes, and microglia

Patel, S., Ismaiel, O. A., Mylott, W. R., Jr., Yuan, M., McClay, J. L., Paris, J. J., Hauser, K. F., & McRae, M. (2019) · Neuroscience Letters · doi:10.1016/j.neulet.2019.134475 · Cited by 22

High-Density Lipoprotein Mimetic Peptide 4F Efficiently Crosses the Blood-Brain Barrier and Modulates Amyloid-β Distribution between Brain and Plasma

Swaminathan, S. K., Zhou, A. L., Ahlschwede, K. M., Curran, G. L., Lowe, V. J., Li, L., & Kandimalla, K. K. (2020) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.120.265876 · Cited by 25

Functional and dynamic mitochondrial damage by chloromethylisothiazolinone/methylisothiazolinone (CMIT/MIT) mixture in brain endothelial cell lines and rat cerebrovascular endothelium

Kim, D., Shin, Y., Kim, E.-H., Lee, Y., Kim, S., Kim, H. S., Kim, H., Leem, J., Kim, H. R., & Bae, O. (2022) · Toxicology Letters · doi:10.1016/j.toxlet.2022.06.010 · Cited by 22

Development of a multicellular in vitro model of the meningeal blood-CSF barrier to study Neisseria meningitidis infection

Endres, L. M., Jungblut, M., Divyapicigil, M., Sauer, M., Stigloher, C., Christodoulides, M., Kim, B. J., & Schubert‐Unkmeir, A. (2022) · Fluids and Barriers of the CNS · doi:10.1186/s12987-022-00379-z · Cited by 24

A high-throughput sequencing approach identifies immunotherapeutic targets for bacterial meningitis in neonates

Pons, S., Frapy, E., Sérémé, Y., Gaultier, C., Lebreton, F., Kropec, A., Danilchanka, O., Schlemmer, L., Schrimpf, C., Allain, M., et al. (2023) · EBioMedicine · doi:10.1016/j.ebiom.2023.104439 · Cited by 24

Protective Effect of Ergothioneine against 7-Ketocholesterol-Induced Mitochondrial Damage in hCMEC/D3 Human Brain Endothelial Cells

Leow, D. M.-K., Cheah, I. K.-M., Fong, Z. W., Halliwell, B. B., & Ong, W. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24065498 · Cited by 24

Quantitative Targeted Proteomics for Membrane Transporter Proteins: Method and Application

Qiu, X., Zhang, H., & Lai, Y. (2014) · The AAPS Journal · doi:10.1208/s12248-014-9607-6 · Cited by 22

New thrombolytic strategy providing neuroprotection in experimental ischemic stroke: MMP10 alone or in combination with tissue-type plasminogen activator

Roncal, C., de Lizarrondo, S. M., Salicio, A., Chevilley, A., Rodríguez, J. A., Rosell, A., Couraud, P., Weksler, B. B., Montaner, J., Vivien, D., et al. (2017) · Cardiovascular Research · doi:10.1093/cvr/cvx069 · Cited by 22

3D Bioprinting Models for Glioblastoma: From Scaffold Design to Therapeutic Application

Branco, F., Cunha, J., Mendes, M., Sousa, J., & Vitorino, C. (2025) · Advanced Materials · doi:10.1002/adma.202501994 · Cited by 24

Optimizing Angiopep‐2 Density on Polymeric Nanoparticles for Enhanced Blood–Brain Barrier Penetration and Glioblastoma Targeting: Insights From In Vitro and In Vivo Experiments

Zhang, W., Refaat, A., Li, H., Zhu, D., Tong, Z., Nicolazzo, J. A., Peng, B., Bai, H., Esser, L., & Voelcker, N. H. (2025) · Advanced Functional Materials · doi:10.1002/adfm.202425165 · Cited by 22

A brain glioma gene delivery strategy by angiopep-2 and TAT-modified magnetic lipid-polymer hybrid nanoparticles

Qiao, L., Qin, Y., Wang, Y., Liang, Y., Zhu, D., Xiong, W., Li, L., Bao, D., Zhang, L., & Jin, X. (2020) · RSC Advances · doi:10.1039/d0ra07161g · Cited by 21

CdSe/ZnS Core-Shell-Type Quantum Dot Nanoparticles Disrupt the Cellular Homeostasis in Cellular Blood–Brain Barrier Models

Kania, K., Wagner, W., & Pułaski, Ł. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22031068 · Cited by 21

Synergistic Impairment of the Neurovascular Unit by HIV-1 Infection and Methamphetamine Use: Implications for HIV-1-Associated Neurocognitive Disorders

Fattakhov, N. S., Torices, S., Stangis, M., Park, M., & Toborek, M. J. (2021) · Viruses · doi:10.3390/v13091883 · Cited by 22

Inhibition of the HEG1–KRIT1 interaction increases KLF4 and KLF2 expression in endothelial cells

Lopez‐Ramirez, M. A., McCurdy, S., Li, W., Haynes, M. K., Hale, P., Francisco, K. R., Oukoloff, K., Bautista, M., Choi, C. H. J., Sun, H., et al. (2021) · FASEB BioAdvances · doi:10.1096/fba.2020-00141 · Cited by 20

Blood–Brain Barrier Dynamic Device with Uniform Shear Stress Distribution for Microscopy and Permeability Measurements

Choublier, N., Müller, Y., Baisac, L. G., Laedermann, J., de Rham, C., Declèves, X., & Roux, A. (2021) · Applied Sciences · doi:10.3390/app11125584 · Cited by 21

A hydrogel model of the human blood-brain barrier using differentiated stem cells

Singh, N. R., Gromnicova, R., Brachner, A., Kraev, I., Romero, I. A., Neuhaus, W., & Male, D. K. (2023) · PLoS ONE · doi:10.1371/journal.pone.0283954 · Cited by 20

Characterization of an iPSC-based barrier model for blood-brain barrier investigations using the SBAD0201 stem cell line

Ozgür, B., Puris, E., Brachner, A., Appelt‐Menzel, A., Oerter, S., Balzer, V., Holst, M. R., Christiansen, R. F., Hyldig, K., Buckley, S. T., et al. (2023) · Fluids and Barriers of the CNS · doi:10.1186/s12987-023-00501-9 · Cited by 20

How do the physicochemical properties of nanoliposomes affect their interactions with the hCMEC/D3 cellular model of the BBB?

Παπαδιά, Κ., Markoutsa, E., & Antimisiaris, S. G. (2016) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2016.06.019 · Cited by 19

Prolonged Morphine Exposure Induces Increased Firm Adhesion in an in Vitro Model of the Blood–Brain Barrier

Strazza, M., Pirrone, V., Wigdahl, B. L., Dampier, W., Lin, W. C., Feng, R., Maubert, M. E., Weksler, B. B., Romero, I. A., Couraud, P., et al. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17060916 · Cited by 20

A proton-coupled organic cation antiporter is involved in the blood-brain barrier transport of Aconitum alkaloids

Cong, J., Ruan, Y., Lyu, Q., Qin, X., Qi, X., Liu, W., Kang, L., Zhang, J., & Wu, C. (2020) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2020.112581 · Cited by 20

3D in vitro blood–brain barrier models: recent advances and their role in brain disease research and therapy

O’Halloran, L., Akinsete, O., Kogan, A. L., Wrona, M., & Mahdi, A. F. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1637602 · Cited by 23

Functionalized retinoic acid lipid nanocapsules promotes a two-front attack on inflammation and lack of demyelination on neurodegenerative disorders

Moura, R. P., Carvalho, E. D., Martins, C., Rieux, A. D., Pêgo, A. P., & Sarmento, B. F. C. C. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.04.034 · Cited by 19

Genetic Engineering of Bacteriophage K1F with Human Epidermal Growth Factor to Enhance Killing of Intracellular E. coli K1

Williams, J., Kerven, J., Chen, Y., & Sagona, A. P. (2023) · ACS Synthetic Biology · doi:10.1021/acssynbio.3c00135 · Cited by 19

The use of a multicellular in vitro model to investigate uptake and migration of bacterial extracellular vesicles derived from the human gut commensal Bacteroides thetaiotaomicron

Modasia, A. A., Jones, E. J., Martel, L. M., Louvel, H., Couraud, P., Blackshaw, L. A., & Carding, S. R. (2023) · Journal of Extracellular Biology · doi:10.1002/jex2.93 · Cited by 19

A 3D-printed blood-brain barrier model with tunable topology and cell-matrix interactions

Paone, L. S., Benmassaoud, M. M., Curran, A., Vega, S. L., & Galie, P. A. (2023) · Biofabrication · doi:10.1088/1758-5090/ad0260 · Cited by 19

P. falciparum Isolate-Specific Distinct Patterns of Induced Apoptosis in Pulmonary and Brain Endothelial Cells

N’dilimabaka, N., Taoufiq, Z., Zougbédé, S., Bonnefoy, S., Lorthiois, A., Couraud, P. O., Rebollo, A., Snounou, G., Mazier, D., & Sabater, A. M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0090692 · Cited by 19

Ocimum sanctum Linn. stimulate the expression of choline acetyltransferase on the human cerebral microvascular endothelial cells

Kusindarta, D. L., Wihadmadyatami, H., & Haryanto, A. T. (2016) · Veterinary World · doi:10.14202/vetworld.2016.1348-1354 · Cited by 19

Selective blood-brain barrier permeabilization of brain metastases by a type 1 receptor-selective tumor necrosis factor mutein

Muñoz, M., Campbell, S. J., Karali, C. S., Johanssen, V. A., Bristow, C., Cheng, V. W. T., Zarghami, N., Larkin, J. R., Pannell, M., Hearn, A. R., et al. (2021) · Neuro-Oncology · doi:10.1093/neuonc/noab177 · Cited by 19

Brain endothelial cells promote breast cancer cell extravasation to the brain via EGFR-DOCK4-RAC1 signalling

Galloni, C., Egnuni, T., Mohajerani, S. Z., Ye, J., Mittnacht, S., Speirs, V., Lorger, M., & Mavria, G. (2024) · Communications Biology · doi:10.1038/s42003-024-06200-x · Cited by 19

Encapsulation of clozapine into polycaprolactone nanoparticles as a promising strategy of the novel nanoformulation of the active compound

Łukasiewicz, S., Mikołajczyk, A., Szczęch, M., Szczepanowicz, K., Warszyński, P., & Dziedzicka‐Wasylewska, M. (2019) · Journal of Nanoparticle Research · doi:10.1007/s11051-019-4587-1 · Cited by 18

Allyl Isothiocianate Induces Ca2+ Signals and Nitric Oxide Release by Inducing Reactive Oxygen Species Production in the Human Cerebrovascular Endothelial Cell Line hCMEC/D3

Berra‐Romani, R., Brunetti, V., Pellavio, G., Soda, T., Laforenza, U., Scarpellino, G., & Moccia, F. D. (2023) · Cells · doi:10.3390/cells12131732 · Cited by 19

Trimethylamine N-Oxide as a Mediator Linking Peripheral to Central Inflammation: An In Vitro Study

Janeiro, M. H., Solas, M., Orbe, J., Rodríguez, J. A., de Muniain, L. S., Escalada, P., Yip, P. K., & Ramírez, M. J. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242417557 · Cited by 20

Increased Transendothelial Transport of CCL3 Is Insufficient to Drive Immune Cell Transmigration through the Blood–Brain Barrier under Inflammatory Conditions In Vitro

Laere, M. D., Sousa, C. P., Meena, M., Buckinx, R., Timmermans, J., Berneman, Z. N., & Cools, N. (2017) · Mediators of Inflammation · doi:10.1155/2017/6752756 · Cited by 18

PI3KC2β inactivation stabilizes VE-cadherin junctions and preserves vascular integrity

Anquetil, T., Solinhac, R., Jaffre, A., Chicanne, G., Viaud, J., Darcourt, J., Orset, C., Geuß, E., Kleinschnitz, C., Vanhaesebroeck, B., et al. (2021) · EMBO Reports · doi:10.15252/embr.202051299 · Cited by 18

Proteome profile differences among human, monkey, and mouse brain microvessels and cultured brain microvascular endothelial cells

Kumabe, H., Masuda, T., Ito, S., Furihata, T., Toda, A., Mogi, M., Araki, N., & Ohtsuki, S. (2025) · Fluids and Barriers of the CNS · doi:10.1186/s12987-025-00650-z · Cited by 16

Brain and Retinal Organoids for Disease Modeling: The Importance of In Vitro Blood–Brain and Retinal Barriers Studies

Martinelli, I., Tayebati, S. K., Tomassoni, D., Nittari, G., Roy, P., & Amenta, F. (2022) · Cells · doi:10.3390/cells11071120 · Cited by 17

Brain Endothelial Cells in Contrary to the Aortic Do Not Transport but Degrade Low-Density Lipoproteins via Both LDLR and ALK1

Kakava, S., Schlumpf, E., Panteloglou, G., Tellenbach, F. L., von Eckardstein, A., & Robert, J. (2022) · Cells · doi:10.3390/cells11193044 · Cited by 20

Antiviral and Immunomodulatory Activities of Clinacanthus nutans (Burm. f.) Lindau

Lin, C.-M., Chen, H., Lung, C.-W., & Chen, H. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241310789 · Cited by 20

On-chip modeling of physiological and pathological blood-brain barrier microenvironment for studying glial responses to neuroinflammation

Zeng, Y.-L., Du, Y., Xu, X., Wang, Y., Yu, S., Liu, T., Luo, S., Xiang, X., Liu, W., Chen, Y.-C., et al. (2023) · Nano Today · doi:10.1016/j.nantod.2023.101947 · Cited by 18

Extracellular Vesicles Generated by Mesenchymal Stem Cells in Stirred Suspension Bioreactors Promote Angiogenesis in Human-Brain-Derived Endothelial Cells

Phelps, J., Hart, D. A., Mitha, A. P., Duncan, N. A., & Sen, A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25105219 · Cited by 17

Dengue virus NS1 hits hard at the barrier integrity of human cerebral microvascular endothelial cells via cellular microRNA dysregulations

Apoorva, Kumar, A., & Singh, S. K. (2024) · Tissue Barriers · doi:10.1080/21688370.2024.2424628 · Cited by 17

Novel Anti-Inflammatory Peptides Based on Chemokine–Glycosaminoglycan Interactions Reduce Leukocyte Migration and Disease Severity in a Model of Rheumatoid Arthritis

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Conjugation of the T1 sequence from CCN1 to fibrin hydrogels for therapeutic vascularization

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