Patient experiences of psychological therapy for depression: a qualitative metasynthesis
Open accessAbstract
BACKGROUND: Globally, national guidelines for depression have prioritised evidence from randomised controlled trials and quantitative meta-analyses, omitting qualitative research concerning patient experience of treatments. A review of patient experience research can provide a comprehensive overview of this important form of evidence and thus enable the voices and subjectivities of those affected by depression to have an impact on the treatments and services they are offered. This review aims to seek a comprehensive understanding of patient experiences of psychological therapies for depression using a systematic and rigorous approach to review and synthesis of qualitative research. METHOD: PsychINFO, PsychARTICLES, MEDLINE, and CINAHL were searched for published articles using a qualitative approach to examine experiences of psychological therapies for depression. All types of psychological therapy were included irrespective of model or modes of delivery (e.g. remote or in person; group or individual). Each article was assessed following guidance provided by the Critical Appraisal Skill Programme tool. Articles were entered in full into NVIVO and themes were extracted and synthesized following inductive thematic analysis. RESULTS: Thirty-seven studies, representing 671 patients were included. Three main themes are described; the role of therapy features and setting; therapy processes and how they impact on outcomes; and therapy outcomes (benefits and limitations). Subthemes are described within these themes and include discussion of what works and what's unhelpful; issues integrating therapy with real life; patient preferences and individual difference; challenges of undertaking therapy; influence of the therapist; benefits of therapy; limits of therapy and what happens when therapy ends. CONCLUSIONS: Findings point to the importance of common factors in psychotherapies; highlight the need to assess negative outcomes; and indicate the need for patients to be more involved in discussions and decisions about therapy, including tailoring therapy to individual needs and taking social and cultural contexts into account.
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Group therapy might be especially beneficial among adolescents as it facilitates togetherness and belonging to peers, which are crucial developmental tasks for this age group.
“Group therapy might also be especially beneficial among adolescents as it facilitates togetherness and belonging to peers, which are crucial developmental tasks for this age group”
From “And I Can Remind Myself That I Am All Of This”: adolescents’ experiences of group-based acceptance and commitment therapy (2024) · cites this paper as McPherson et al., 2020
The Results (Therapy processes and how they impact on outcomes; page unavailable) report that group therapy provided social support and comfort through shared experiences. But the Methods (Eligibility criteria; page unavailable) state that studies of adolescents and children were excluded. The paper therefore does not support the claim that group therapy is especially beneficial for adolescents or that peer belonging is a crucial developmental task for them. (LLM, conf=0.90)
Experimental — accuracy not yet measuredSome challenges are associated with group therapy format, e.g., self-censoring and tailoring therapy to individual needs.
“but some challenges are also associated with the format, e.g., self-censoring, tailoring therapy to individual needs, etc. (Gjesvik et al., 2018; McPherson et al., 2020).”
From “And I Can Remind Myself That I Am All Of This”: adolescents’ experiences of group-based acceptance and commitment therapy (2024) · cites this paper as McPherson et al., 2020
The Results section reports that group psychotherapy patients sometimes censored themselves when sharing problems. It also says therapy may need tailoring to individual needs, but discusses this across approaches or specifically for cognitive-behavioural approaches, not as a challenge particular to the group format. Page numbers are unavailable in our copy. (LLM, conf=0.86)
Experimental — accuracy not yet measuredMcPherson et al. (2020) reported that patients undergoing group psychotherapy for depression sometimes found it difficult to share their problems with the group, as they saw their problems as "minor" or "not permissible."
“Similar findings were also reported by McPherson et al. (2020, p. 11), where patients undergoing group psychotherapy for depression sometimes found it difficult to share their problems with the group, as they saw their problems as “minor” or “not permissible.””
From “And I Can Remind Myself That I Am All Of This”: adolescents’ experiences of group-based acceptance and commitment therapy (2024) · cites this paper as McPherson et al., 2020
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The User Experience Framework for Health Interventions
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“New insights and reframing of the problems have previously been shown to be important for clients in the treatment of depression (McPherson et al., 2020; Timulak, 2007).”
A proverbial double-edged sword
McPherson, S., & Oute, J. (2021) · Tidsskrift for Forskning i Sygdom og Samfund · doi:10.7146/tfss.v18i34.127172 · Cited by 3 · see citing works
Brovold, F., Laugen, N. J., & Grøtte, T. (2024) · Frontiers in Psychology · doi:10.3389/fpsyg.2024.1458421 · Cited by 2 · see citing works
Serbetci, D., Koh, Z. H., Murray, G., & Tremain, H. (2024) · Bipolar Disorders · doi:10.1111/bdi.13464 · Cited by 2 · see citing works
“25 Although there is an increasing emphasis on empirical investigations into these interactions, they remain uncommon.”
Finazzi, E., MacLeod, E., & MacBeth, A. M. (2023) · PLoS ONE · doi:10.1371/journal.pone.0279263 · Cited by 2 · see citing works
“McPherson and colleagues’ [87] meta-synthesis recommended the importance for patients of being informed and involved in initial discussions and decision about their treatment.”
BackgroundResultCasarez, R. L., Johnson, C., Soares, J. C., & Meyer, T. D. (2024) · Archives of Psychiatric Nursing · doi:10.1016/j.apnu.2024.02.003 · Cited by 2 · see citing works
Yarwood, B., Angelakis, I., & Taylor, R. (2025) · The Cognitive Behaviour Therapist · doi:10.1017/s1754470x25000091 · Cited by 2 · see citing works
“One such example is a lack of individualisation by assessing outcomes in a way that do not reflect user priorities, specifically a measurement of symptoms, not client-preferred outcomes (McPherson et al ., 2020).”
Cui, L.-C., Qin, Y., Feng, L.-L., Li, H., Huang, Z.-Q., Zhu, Y., Shen, S., Li, J.-N., Zhang, H.-P., & Tang, X.-F. (2025) · British Journal of Social Work · doi:10.1093/bjsw/bcaf191 · Cited by 2 · see citing works
Wedema, D., Hovenkamp-Hermelink, J., Korevaar, E. L., Wardenaar, K. J., & Schoevers, R. A. (2025) · Psychotherapy and Psychosomatics · doi:10.1159/000548808 · Cited by 1 · see citing works
“…emphasized in previous qualitative syntheses, which have highlighted that recovery requires Systematic Review of Subjective Recovery Factors in Depression individuals to be actively involved in defining their goals, with personal context shaping both the meaning and process of recovery [22, 23].”
Multiracial emerging adults’ experiences with mental health care: ‘To me, it's complicated’
Weller, B. E., Jean-Baptiste, K. E., & Giroux, D. M. (2025) · Ethnicity and Health · doi:10.1080/13557858.2025.2602615 · Cited by 1 · see citing works
“Further, another meta-synthesis of 38 qualitative studies of people’s experiences with clinical care found that most study participants were White with some representation of individuals who were monoracial people of color (McPherson, Wicks, and Tercelli 2020).”
Yüksel-Şahin, F. (2026) · Buca eğitim fakültesi dergisi (Online)/Buca Eğitim Fakültesi dergisi · doi:10.53444/deubefd.1595710 · Cited by 1 · see citing works
Tercelli, I., McPherson, S., & Senra, H. (2024) · British Journal of Psychotherapy · doi:10.1111/bjp.12879 · Cited by 1 · see citing works
Børtveit, L., Nordgreen, T., & Nordahl‐Hansen, A. (2024) · Acta Psychologica · doi:10.1016/j.actpsy.2024.104510 · Cited by 1 · see citing works
Mowat, R. M., Lewis, G. N., & Borotkanics, R. (2021) · Australian Health Review · doi:10.1071/ah21018
The Promise and Challenges of Practice-Oriented Research: A Commentary on the Special Issue
Tasca, G. A. (2024) · Administration and Policy in Mental Health and Mental Health Services Research · doi:10.1007/s10488-024-01370-6
“Whereas an apparent application of AI technologies might be to mimic or produce interventions that are technically sound and symptom-focused, these may not align with client needs or wishes for therapists to listen and to be understanding (McPherson et al., 2020).”
Drummond, K. N., Guzick, A. G., Spencer, S. D., Pinciotti, C. M., Bivins, E. J., Minhajuddin, A., Slater, H., Gorman, A., Goodman, L. C., Walker, R. A., et al. (2025) · Clinical Psychology & Psychotherapy · doi:10.1002/cpp.70088
Holmegaard, K., Smith‐Nielsen, J., Stuart, A. C., Frees, A., Lassen, N. M., & Væver, M. S. (2025) · Journal of Child and Family Studies · doi:10.1007/s10826-025-03149-1
“Recent studies highlight that not all individuals bene fi t equally from group-based approaches, and that some report emotional overwhelm when exposed to others ’ distress or when asked to engage in emotionally intensive techniques (McPherson et al., 2020).”
Massoudi, P., Strömwall, L. A., Åhlén, J., Fredriksson, M. K., Dencker, A., & Andersson, E. P. (2023) · Figshare · doi:10.6084/m9.figshare.24564083
Kellerwessel, K., Kovács, A., & Ujhelyi, A. (2026) · Exploration of Digital Health Technologies · doi:10.37349/edht.2026.101180
Ramaekers, R. M. D., van Dijk, D. A., Veenstra, M. Y., Schruers, K. R. J., van Bronswijk, S. C., & Leibold, N. K. (2026) · Journal of Clinical Psychology · doi:10.1002/jclp.70092
“Clients and informal caregivers find the therapeutic alliance important to treatment success and seem to attribute the alliance more to the clinician than to the client, as shown by this study and previous research (Bachelor 1995; McPherson et al. 2020).”
Amonoo, H. L., Keane, E. P., Guo, M., Gudenkauf, L. M., Boardman, A. C., Larizza, I. S., Wolfe, E. D., Mate-Kole, M., Healy, B. C., Cutler, C. S., et al. (2026) · Blood Advances · doi:10.1182/bloodadvances.2025018918
“57,58 STEPP’s effects on PROs require further investigation in a larger, fully powered efficacy RCT with longer follow-up and measures assessing skills practice.”
Client perspectives of internet-based treatment for depression in Arabic-speaking countries
El‐Haj‐Mohamad, R., Nohr, L., Stammel, N., Salloum, Z., Böhm, M., Nesterko, Y., Wagner, B., Böttche, M., & Knaevelsrud, C. (2026) · BMC Psychology · doi:10.1186/s40359-026-04463-z
“While McPherson et al. [37] emphasized that treatment guidelines often fail to include qualitative research on patient experiences, this perspective is crucial for improving treatment effectiveness.”
InfluentialMolloy, N., Fabian, H., Madigan, A., Mitchell, A., Moser, M., Barrett, K., Hill, R., Michailidou, K., Jin, H., & Wykes, T. (2026) · The British Journal of Psychiatry · doi:10.1192/bjp.2026.10765
A model of engagement in psychological therapy
Thew, G. R. (2026) · Behavioural and Cognitive Psychotherapy · doi:10.1017/s135246582610143x
Hall, A., Gregg, L., O’Ceallaigh, B., & Wittkowski, A. (2026) · Research Square · doi:10.21203/rs.3.rs-10944017/v1
Casino, F., Martínez-Ballesté, A., & Batista, E. (2026) · JMIR Medical Informatics · doi:10.2196/100369
- Authors
- McPherson, S., Wicks, C., & Tercelli, I.
- Affiliations
- University of Essex (GB)
- Corresponding author
- McPherson, Susan
- Venue
- BMC Psychiatry
- Published
- 2020-06-18
- Volume
- 20
- Issue
- 1
- Pages
- 313-313
- ISSN
- 1471-244X (ISSN-L)
- PMC
- PMC7302137
- OpenAlex
- W3035994701
- Cited by
- 52
- References
- 63
- Citations by year
- 2026: 9 · 2025: 9 · 2024: 12 · 2023: 7 · 2022: 5 · 2021: 9 · 2020: 1
- FWCI
- 2.20
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- BMC Psychiatry (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Open Access at Essex (University of Essex) (acceptedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Social Sciences › Psychology › Clinical Psychology › Psychological Treatments and Disorders
- Keywords
- depression, psychotherapy, patient experience, common factors, therapist influence, patient preferences, individual differences, treatment outcomes, patient involvement in treatment decisions, cultural context of therapy
- MeSH terms
- Depression, Humans, Patients, Qualitative Research, Psychotherapy, Psychodynamic
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