Cited by 32Suicide and Self-Harm StudiesPersonality Disorders and PsychopathologyBipolar Disorder and Treatment

Borderline personality disorder and prior suicide attempts define a severity gradient among hospitalized adolescent suicide attempters

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Aouidad, Aveline, Cohen, David, Mirkovic, Bojan, Pellerin, Hugues, Garny de La Rivière, Sébastien, Consoli, Angèle, Gérardin, Priscille, Guilé, Jean-Marc·2020·BMC Psychiatry

Abstract

BACKGROUND: Borderline personality disorder (BPD) and history of prior suicide attempt (SA) have been shown to be high predictors for subsequent suicide. However, no previous study has examined how both factors interact to modify clinical and suicide severity among adolescents. METHODS: This study presents a comprehensive assessment of 302 adolescents (265 girls, mean age = 14.7 years) hospitalized after a SA. To test clinical interactions between BPD and history of prior SA, the sample was divided into single attempters without BPD (non-BPD-SA, N = 80), single attempters with BPD (BPD-SA, N = 127) and multiple attempters with BPD (BPD-MA, N = 95). RESULTS: Univariate analyses revealed a severity gradient among the 3 groups with an additive effect of BPD on the clinical and suicide severity already conferred by a history of SA. This gradient encompassed categorical (anxiety and conduct disorders and non-suicidal-self-injury [NSSI]) and dimensional comorbidities (substance use and depression severity) and suicide characteristics (age at first SA). According to regression analyses, the BPD-MA group that was associated with the most severe clinical presentation also showed specific features: the first SA at a younger age and a higher prevalence of non-suicidal self-injury (NSSI) and anxiety disorders. The BPD-MA group was not associated with higher impulsivity or frequency of negative life events. CONCLUSIONS: Based on these findings and to improve youth suicide prevention, future studies should systematically consider BPD and the efficacy of reinforcing early interventions for anxiety disorders and NSSI.

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  • Risk of suicide attempt is further heightened among those with an earlier age of occurrence of first attempt, as well as those with borderline personality disorder features.

    “Risk is further heightened among those with an earlier age of occurrence of first attempt, as well as those with borderline personality disorder (features) (100).”

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Authors
Aouidad, A., Cohen, D., Mirkovic, B., Pellerin, H., Garny de La Rivière, S., Consoli, A., Gérardin, P., & Guilé, J.-M.
Affiliations
  • Assistance Publique – Hôpitaux de Paris (FR)
  • Sorbonne Université (FR)
  • Hôpital Charles-Nicolle (FR)
  • Centre Hospitalier Universitaire Amiens-Picardie (FR)
Corresponding author
Aouidad, Aveline
Venue
BMC Psychiatry
Published
2020-11-04
Volume
20
Issue
1
Pages
525-525
ISSN
1471-244X (ISSN-L)
OpenAlex
W3095755089
Cited by
32
References
76
Citations by year
2026: 2 · 2025: 4 · 2024: 5 · 2023: 9 · 2022: 7 · 2021: 4 · 2020: 1
FWCI
2.10
Type
journal article
Language
en
Open access
Locations
  • BMC Psychiatry (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • HAL (submittedVersion, other-oa)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • Pfizer Foundation
  • Fondation de France
Topics
  • Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
  • Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
  • Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
Keywords
borderline personality disorder, suicide attempts, adolescents, suicide severity, repeated suicide attempts, non-suicidal self-injury, anxiety disorders, substance use, depression, impulsivity, negative life events, youth suicide prevention, hospitalized adolescents
MeSH terms
Adolescent, Adolescent, Hospitalized, Anxiety Disorders, Borderline Personality Disorder, Female, Humans, Suicide, Attempted, Self-Injurious Behavior

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