Cited by 374Protein Hydrolysis and Bioactive PeptidesFood and Agricultural SciencesPhytochemicals and Antioxidant Activities

Antioxidant properties of Milk and dairy products: A comprehensive review of the current knowledge

Open access
Khan, Imran Taj, Nadeem, Muhammad, Imran, Muhammad, Ullah, Rahman, Ajmal, Muhammad, Jaspal, Muhammad Hayat·2019·Lipids in Health and Disease

Abstract

Milk and dairy products are integral part of human nutrition and they are considered as the carriers of higher biological value proteins, calcium, essential fatty acids, amino acids, fat, water soluble vitamins and several bioactive compounds that are highly significant for several biochemical and physiological functions. In recent years, foods containing natural antioxidants are becoming popular all over the world as antioxidants can neutralize and scavenge the free radicals and their harmful effects, which are continuously produced in the biological body. Uncontrolled free radicals activity can lead to oxidative stresses, which have been implicated in breakdown of vital biochemical compounds such as lipids, protein, DNA which may lead to diabetes, accelerated ageing, carcinogenesis and cardiovascular diseases. Antioxidant capacity of milk and milk products is mainly due to sulfur containing amino acids, such as cysteine, phosphate, vitamins A, E, carotenoids, zinc, selenium, enzyme systems, superoxide dismutase, catalase, glutathione peroxidase, milk oligosaccharides and peptides that are produced during fermentation and cheese ripening. Antioxidant activity of milk and dairy products can be enhanced by phytochemicals supplementation while fermented dairy products have been reported contained higher antioxidant capacity as compared to the non-fermented dairy products. Literature review has shown that milk and dairy products have antioxidant capacity, however, information regarding the antioxidant capacity of milk and dairy products has not been previously compiled. This review briefly describes the nutritional and antioxidant capacity of milk and dairy products.

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Crossref · 10.1186/s12944-019-0969-8

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129 of 129 references verified0 citation errors · 0 not checkable

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  • During ripening, lipolytic enzymes present in lactic acid bacteria can hydrolyze a substrate to generate free fatty acid esters, triacylglycerides, diacylglycerides, and monoacylglycerides.

    “During ripening, lipolytic enzymes present in lactic acid bacteria (LAB) can hydrolyze a substrate to generate free fatty acid esters, triacylglycerides, diacylglycerides, and monoacylglycerides (Khan et al., 2019, Xiaochun et al., 2021).”

    From Antioxidant and antihypertensive activity of Gouda cheese at different stages of ripening (2022) · cites this paper as Khan et al., 2019

    The section “Ripening effect on antioxidant characteristics of cheese” discusses peptides and proteolysis during ripening, not lipolytic enzymes or their products. Searches for lipolysis, hydrolysis, and the named glycerides found no passage in our copy supporting the claimed reaction. (LLM, conf=0.76)

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Cites

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4 of the 133 references couldn’t be matched to a known paper.

Research works printed but not linked: 4

  1. [26]Kim HJ, Min DB. Chemistry and reactions of singlet and triplet oxygen in lipid oxidation. In: Kamal-Eldin A and Min DB. Lipid Oxidation Pathways. Urbana, IL: AOCS Press. 2003;1–30.
  2. [47]Fox PF, McSweeney PLH. Dairy Chemistry and Biochemistry. First edition. Blackie Academic and Professional, Thomson Science, London. 1998;1:265–340.
  3. [113]Ruiz de Gordoa JC, Bustamante M, Arranz J, Virto M, Barrón LJR, Beltrán de Heredia I, Amores G, Abilleira E, Nájera AI, Ruiz R, Albisu M, Pérez-Elortondo FJ, Mandaluniz N. Increase in water-soluble total antioxidant capacity of sheep's milk as a result of increased grazing time. Options Méditerranéennes. 2011;99:267–271.
  4. [120]Balakrishnan G Agrawal R 2012. Antioxidant activity and fatty acid profile of fermented milk prepared by Pediococcus pentosaceus J Food Sci Technol 2012 51 4138 4142 10.1007/s13197-012-0891-9 25477694 PMC4252412 · DOI

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Authors
Khan, I. T., Nadeem, M., Imran, M., Ullah, R., Ajmal, M., & Jaspal, M. H.
Affiliations
  • University of Veterinary and Animal Sciences (PK)
  • Government College University, Faisalabad (PK)
Corresponding author
Nadeem, Muhammad
Venue
Lipids in Health and Disease
Published
2019-02-04
Volume
18
Issue
1
Pages
41-41
ISSN
1476-511X (ISSN-L)
OpenAlex
W2922199485
Cited by
374
References
133
Citations by year
2026: 33 · 2025: 51 · 2024: 57 · 2023: 52 · 2022: 79 · 2021: 58 · 2020: 35 · 2019: 9
FWCI
4.00
Type
journal article
Language
en
Open access
Locations
  • Lipids in Health and Disease (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, other-oa)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
Funders
  • Government College University, Lahore
  • University of Veterinary and Animal Sciences
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Hydrolysis and Bioactive Peptides
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Food and Agricultural Sciences
  • Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
Keywords
milk, dairy products, antioxidant capacity, free radicals, oxidative stress, bioactive compounds, sulfur-containing amino acids, cysteine, milk oligosaccharides, fermented dairy products, cheese ripening, superoxide dismutase, catalase, glutathione peroxidase, carotenoids, selenium, zinc, vitamins
MeSH terms
Whey Proteins, Amino Acids, Animals, Antioxidants, Buffaloes, Caseins, Cattle, Dairy Products, Goats, Humans, Milk, Nutritive Value, Sheep

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