Identifying barriers and facilitators to successful implementation of computerized clinical decision support systems in hospitals: a NASSS framework-informed scoping review
Open accessAbstract
Background: Successful implementation and utilization of Computerized Clinical Decision Support Systems (CDSS) in hospitals is complex and challenging. Implementation science, and in particular the Nonadoption, Abandonment, Scale-up, Spread and Sustainability (NASSS) framework, may offer a systematic approach for identifying and addressing these challenges. This review aimed to identify, categorize, and describe barriers and facilitators to CDSS implementation in hospital settings and map them to the NASSS framework. Exploring the applicability of the NASSS framework to CDSS implementation was a secondary aim. Methods: Electronic database searches were conducted (21 July 2020; updated 5 April 2022) in Ovid MEDLINE, Embase, Scopus, PyscInfo, and CINAHL. Original research studies reporting on measured or perceived barriers and/or facilitators to implementation and adoption of CDSS in hospital settings, or attitudes of healthcare professionals towards CDSS were included. Articles with a primary focus on CDSS development were excluded. No language or date restrictions were applied. We used qualitative content analysis to identify determinants and organize them into higher-order themes, which were then reflexively mapped to the NASSS framework. Results: Forty-four publications were included. These comprised a range of study designs, geographic locations, participants, technology types, CDSS functions, and clinical contexts of implementation. A total of 227 individual barriers and 130 individual facilitators were identified across the included studies. The most commonly reported influences on implementation were fit of CDSS with workflows (19 studies), the usefulness of the CDSS output in practice (17 studies), CDSS technical dependencies and design (16 studies), trust of users in the CDSS input data and evidence base (15 studies), and the contextual fit of the CDSS with the user’s role or clinical setting (14 studies). Most determinants could be appropriately categorized into domains of the NASSS framework with barriers and facilitators in the “Technology,” “Organization,” and “Adopters” domains most frequently reported. No determinants were assigned to the “Embedding and Adaptation Over Time” domain. Conclusions: This review identified the most common determinants which could be targeted for modification to either remove barriers or facilitate the adoption and use of CDSS within hospitals. Greater adoption of implementation theory should be encouraged to support CDSS implementation.
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Increased workload and misalignment with clinical workflows are among the most common barriers to CDS adoption in clinical settings.
“Increased workload and misalignment with clinical workflows are among the most common barriers to CDS adoption in clinical settings.12,13”
From Electronic health record activity changes around new decision support implementation: monitoring using audit logs and topic modeling (2025) · cites this paper as [12]
The Results identify fit with workflows as the most commonly reported determinant of hospital CDSS implementation (19 of 44 studies). They also report that perceived time and effort and loss of productivity can deter use, but do not establish increased workload as one of the most common barriers. The review concerns hospital settings, rather than clinical settings generally; page numbers were not supplied. (LLM, conf=0.84)
Experimental — accuracy not yet measuredIncreased workload (either perceived or experienced) associated with CDS has been identified as a major barrier to CDS adoption.
“In addition, increased workload (either perceived or experienced) associated with CDS has been identified as a major barrier to CDS adoption.12,13”
From Electronic health record activity changes around new decision support implementation: monitoring using audit logs and topic modeling (2025) · cites this paper as [12]
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Wenderott, K., Krups, J., Luetkens, J. A., & Weigl, M. (2024) · Applied Ergonomics · doi:10.1016/j.apergo.2024.104243 · Cited by 33 · see citing works
Chen, J., Cutrona, S. L., Dharod, A., Moses, A., Bridges, A., Ostasiewski, B., Foley, K. L., Houston, T. K., iDAPT (Implementation & Informatics Developing Adaptable Processes and Technologies for Cancer Control) Implementation Science Center for Cancer Control, Chen, J., et al. (2025) · JAMIA Open · doi:10.1093/jamiaopen/ooaf050 · Cited by 3 · see citing works
- Authors
- Abell, B., Naicker, S., Rodwell, D., Donovan, T., Tariq, A., Baysari, M., Blythe, R., Parsons, R., & McPhail, S. M.
- Affiliations
- Queensland University of Technology (AU)
- The University of Sydney (AU)
- Corresponding author
- Naicker, Sundresan
- ORCID
- Venue
- Implementation Science
- Published
- 2023-07-26
- Volume
- 18
- Issue
- 1
- Pages
- 32-32
- ISSN
- 1748-5908 (ISSN-L)
- PMC
- PMC10373265
- OpenAlex
- W4385281466
- Cited by
- 131
- References
- 15
- Citations by year
- 2026: 52 · 2025: 49 · 2024: 26 · 2023: 4
- FWCI
- 5.13
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Implementation Science (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Digital Health Cooperative Research Centre (DHCRC-0058)
- Topics
- Health Sciences › Health Professions › Health Information Management › Electronic Health Records Systems
- Health Sciences › Health Professions › General Health Professions › Health Policy Implementation Science
- Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
- Keywords
- computerized clinical decision support systems, implementation barriers, implementation facilitators, NASSS framework, hospital implementation, clinician attitudes, technology adoption, implementation theory
- MeSH terms
- Health Personnel, Hospitals, Humans, Technology, Decision Support Systems, Clinical
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