Helminth control in kennels: is the combination of milbemycin oxime and praziquantel a right choice?
Open accessAbstract
BACKGROUND: Kennel dogs are at the high risk of infections with intestinal and extra-intestinal helminths. Therefore, regular parasitological surveillance, appropriate treatment strategies and high quality standard of hygiene are required to guarantee the health and welfare of kennel dogs. The aim of the present study was to evaluate the efficacy of helminth control in kennels using different broad-spectrum anthelmintics that are routinely used in canine veterinary practice. Particular attention was given to the field efficacy and ease-of-use of each product. METHODS: The study was conducted in 3 public kennels in the Campania region (southern Italy). Eighteen boxes from each of the three kennels were selected for treatment based on faecal egg counts (FECs) at Day -30. The treatments were conducted using tablets containing combinations of: i) milbemycin oxime and praziquantel (Milbemax®); ii) pyrantel embonate, febantel and praziquantel (Drontal Plus Flavour®), and; iii) pyrantel pamoate, oxantel pamoate and praziquantel (Nemex® POP). All dogs were treated on Day 0 and sampled on Days 0, 7, 14 and 21 for copromicroscopic analyses. The FLOTAC dual technique on pooled samples was used with efficacy determined by reduction in FECs. RESULTS: At Day -30 intestinal nematodes (hookworms, Toxocara, Trichuris) and cestodes (Dypilidium caninum) were found. Milbemax® showed 100% efficacy against all the helminths in all the kennels. Drontal Plus Flavour® was 100% effective against hookworms in all the kennels but gave lower efficacy against T. canis (range=97.1-100%) and T. vulpis (range=95.6-100%). Nemex® POP was also 100% effective against hookworms in all kennels but less effective against T. canis (range=95.7-100%) and T. vulpis (range=95.7-100%). All three drugs were 100% effective against D.caninum. CONCLUSIONS: Milbemax®was fully effective against all the helminthes and was palatable and ease-of-use for all the dogs. It is the optimum choice for the treatment and prevention of helminth infections in kennel dogs under field conditions.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Polyparasitism is the rule in the studied kennels in southern Italy.
“The main findings of the present survey confirm that polyparasitism is the rule in the studied kennels in southern Italy as already described by Rinaldi et al. [24] concerning other endoparasites.”
From Dirofilaria immitis and Angiostrongylus vasorum: the contemporaneous detection in kennels (2015) · cites this paper as [24]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Wood, I. B., Amaral, N. K., Bairden, K., Duncan, J. L., Kassai, T., Malone, J. B., Pankavich, J. A., Reinecke, R. K., Slocombe, O., Taylor, S. M., et al. (1995) · Veterinary Parasitology · doi:10.1016/0304-4017(95)00806-2 · Cited by 668 · see citing works
Cringoli, G., Rinaldi, L., Maurelli, M. P., & Utzinger, J. (2010) · Nature Protocols · doi:10.1038/nprot.2009.235 · Cited by 513 · see citing works
Self-citationPet roundworms and hookworms: A continuing need for global worming
Traversa, D. (2012) · Parasites & Vectors · doi:10.1186/1756-3305-5-91 · Cited by 221 · see citing works
Environmental contamination by canine geohelminths
Traversa, D., di Regalbono, A. F., Cesare, A. D., Torre, F. L., Drake, J., & Pietrobelli, M. (2014) · Parasites & Vectors · doi:10.1186/1756-3305-7-67 · Cited by 215 · see citing works
Traversa, D. (2011) · Parasites & Vectors · doi:10.1186/1756-3305-4-32 · Cited by 148 · see citing works
Jacobs, D. E., Arakawa, A., Courtney, C. H., GEMMELL, M. A., McCall, J. W., Myers, G. H., & Vanparijs, O. (1994) · Veterinary Parasitology · doi:10.1016/0304-4017(94)90110-4 · Cited by 135 · see citing works
Regnier, B. (1990) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/bf01964295 · Cited by 134 · see citing works
Conboy, G. A. (2004) · Veterinary Record · doi:10.1136/vr.155.1.16 · Cited by 129 · see citing works
Sager, H., Moret, C. S., Grimm, F., Deplazes, P., Doherr, M. G., & Gottstein, B. (2006) · Parasitology Research · doi:10.1007/s00436-005-0093-8 · Cited by 116 · see citing works
Effects of aggregation and sample size on composite faecal egg counts in sheep
Morgan, E. R., Cavill, L., Curry, G. E., et al. (2005) · Veterinary Parasitology · doi:10.1016/j.vetpar.2005.04.021 · Cited by 113 · see citing works
Morgan, E., & Shaw, S. (2010) · Journal of Small Animal Practice · doi:10.1111/j.1748-5827.2010.01000.x · Cited by 89 · see citing works
Frequency of intestinal parasites in pet dogs from an urban area (Greater Oporto, northern Portugal)
Neves, D., Lobo, L., Brilhante-Simões, P., & Cardoso, L. (2013) · Veterinary Parasitology · doi:10.1016/j.vetpar.2013.11.005 · Cited by 69 · see citing works
The Prostigmatic Mites of South African Lizards
Lawrence, R. F. (1936) · Parasitology · doi:10.1017/s0031182000022228 · Cited by 60 · see citing works
Motta, B., Schnyder, M., Basano, F. S., Nägeli, F., Nägeli, C., Schiessl, B., Mallìa, E., Lia, R. P., Dantas‐Torres, F., & Otranto, D. (2012) · Parasites & Vectors · doi:10.1186/1756-3305-5-85 · Cited by 54 · see citing works
Factors associated with gastrointestinal parasite infection in dogs in Rio de Janeiro, Brazil
Balassiano, B. C. C., Campos, M. R., Menezes, R., & Pereira, M. J. S. (2009) · Preventive Veterinary Medicine · doi:10.1016/j.prevetmed.2009.05.030 · Cited by 45 · see citing works
Rinaldi, L., Calabria, G., Carbone, S., Carrella, A., & Cringoli, G. (2007) · Parasitology Research · doi:10.1007/s00436-007-0835-x · Cited by 44 · see citing works
Self-citationGrandemange, E., Claerebout, E., Genchi, C., et al. (2006) · Veterinary Parasitology · doi:10.1016/j.vetpar.2006.11.013 · Cited by 42 · see citing works
Schnyder, M., Maurelli, M. P., Morgoglione, M. E., Kohler, L., Deplazes, P., Torgerson, P., Cringoli, G., & Rinaldi, L. (2011) · Parasitology Research · doi:10.1007/s00436-010-2221-3 · Cited by 42 · see citing works
Self-citationCanine leishmaniasis surveillance in a northern Italy kennel
Baldelli, R., Piva, S., Salvatore, D., Parigi, M., Melloni, O., Tamba, M., Bellini, R., & Poglayen, G. (2011) · Veterinary Parasitology · doi:10.1016/j.vetpar.2011.01.052 · Cited by 36 · see citing works
Cringoli, G., Rinaldi, L., Maurelli, M. P., Morgoglione, M. E., Musella, V., & Utzinger, J. (2011) · Experimental Parasitology · doi:10.1016/j.exppara.2011.01.014 · Cited by 33 · see citing works
Self-citationAltreuther, G., Radeloff, I., LeSueur, C., Schimmel, A., & Krieger, K. J. (2009) · Parasitology Research · doi:10.1007/s00436-009-1492-z · Cited by 27 · see citing works
Conboy, G. A., Bourque, A. C., Miller, L., et al. (2013) · Veterinary Parasitology · doi:10.1016/j.vetpar.2013.09.016 · Cited by 19 · see citing works
FLOTAC: An improved method for diagnosis of lungworm infections in sheep
Rinaldi, L., Maurelli, M. P., Musella, V., et al. (2010) · Veterinary Parasitology · doi:10.1016/j.vetpar.2010.01.008 · Cited by 15 · see citing works
Self-citationHellmann, K., Knoppe, T. N., Radeloff, I., et al. (2003) · Parasitology Research · doi:10.1007/s00436-003-0919-1 · Cited by 10 · see citing works
Exploring the interface between diagnostics and maps of neglected parasitic diseases
Rinaldi, L., & Cringoli, G. (2014) · Parasitology · doi:10.1017/s0031182013002230 · Cited by 10 · see citing works
Self-citationRinaldi, L., Calabria, G., Carbone, S., Carrella, A., & Cringoli, G. (2007) · Parasitology Research · doi:10.1007/s00436-007-0713-6 · Cited by 9 · see citing works
Self-citation
Flagged first, then by citations
Research works printed but not linked: 1
- [6]Rinaldi L Pennacchio S Musella V Maurelli MP Guariglia I Cappelli G Rolando Kennel dogs and helminth infections in the Campania region Proceedings of the Italian Conference of the Italian Society of Parasitology (SOIPA): 26–29 June 2012 2012 Italy Alghero (SS) 45
Cited by
Sorted by citations
Sauda, F., Malandrucco, L., Macrì, G., Scarpulla, M., De Liberato, C., Terracciano, G., Fichi, G., Berrilli, F., & Perrucci, S. (2018) · Parasite · doi:10.1051/parasite/2018001 · Cited by 52 · see citing works
Dirofilaria immitis and Angiostrongylus vasorum: the contemporaneous detection in kennels
Del Prete, L., Maurelli, M. P., Pennacchio, S., Bosco, A., Musella, V., Ciuca, L., Cringoli, G., & Rinaldi, L. (2015) · BMC Veterinary Research · doi:10.1186/s12917-015-0619-y · Cited by 19 · see citing works
Self-citation
- Authors
- Rinaldi, L., Pennacchio, S., Musella, V., Maurelli, M., La Torre, F., & Cringoli, G.
- Affiliations
- University of Naples Federico II (IT)
- Magna Graecia University (IT)
- Corresponding author
- Rinaldi, Laura
- Venue
- Parasites & Vectors
- Published
- 2015
- Volume
- 8
- Issue
- 1
- Pages
- 30
- ISSN
- 1756-3305 (ISSN-L)
- PMC
- PMC4304623
- OpenAlex
- W1998112380
- Cited by
- 23
- References
- 26
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 1 · 2023: 3 · 2022: 2 · 2021: 3 · 2020: 1 · 2018: 3 · 2017: 2 · 2016: 1 · 2015: 3
- FWCI
- 4.83
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Parasites & Vectors (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- Università degli Studi di Napoli Federico II
- University of Bristol
- Topics
- Health Sciences › Veterinary › Small Animals › Helminth infection and control
- Life Sciences › Immunology and Microbiology › Parasitology › Parasites and Host Interactions
- Health Sciences › Medicine › Pathology and Forensic Medicine › Parasitic infections in humans and animals
- Keywords
- helminth control, kennel dogs, anthelmintic efficacy, milbemycin oxime, praziquantel, pyrantel embonate, febantel, pyrantel pamoate, hookworm, Toxocara canis, faecal egg count reduction, drug palatability
- MeSH terms
- Animals, Anthelmintics, Dog Diseases, Dogs, Drug Combinations, Female, Helminthiasis, Animal, Housing, Animal, Italy, Male, Praziquantel, Macrolides
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
