Cited by 1,735Mental Health Treatment and AccessTreatment of Major DepressionHealth Systems, Economic Evaluations, Quality of Life

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Global burden of depressive disorders in the year 2000

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Üstün, T. B., Ayuso-Mateos, J. L., Chatterji, S., Mathers, C., Murray, C. J. L.·2004·British Journal of Psychiatry

DOI 10.1192/bjp.184.5.386

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Abstract

BACKGROUND: The initial Global Burden of Disease study found that depression was the fourth leading cause of disease burden, accounting for 3.7% of total disability adjusted life years (DALYs) in the world in 1990. AIMS: To present the new estimates of depression burden for the year 2000. METHOD: DALYs for depressive disorders in each world region were calculated, based on new estimates of mortality, prevalence, incidence, average age at onset, duration and disability severity. RESULTS: Depression is the fourth leading cause of disease burden, accounting for 4.4% of total DALYs in the year 2000, and it causes the largest amount of non-fatal burden, accounting for almost 12% of all total years lived with disability worldwide. CONCLUSIONS: These data on the burden of depression worldwide represent a major public health problem that affects patients and society.

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Authors: Üstün, T. B., Ayuso-Mateos, J. L., Chatterji, S., Mathers, C., & Murray, C. J. L.
Affiliations: World Health Organization (CH)
Corresponding author: Üstün, T. B.
ORCID: Chatterji, S.
Mathers, C.
Murray, C. J. L.
Venue: British Journal of Psychiatry
Publisher: Royal College of Psychiatrists
Published: 2004-05
Volume: 184
Issue: 5
Pages: 386-392
ISSN: 0007-1250 (ISSN-L)
1472-1465
DOI: 10.1192/bjp.184.5.386
OpenAlex: W2145151017
Cited by: 1,735
References: 37
Citations by year: 2026: 13 · 2025: 17 · 2024: 26 · 2023: 54 · 2022: 47 · 2021: 50 · 2020: 59 · 2019: 66 · 2018: 81 · 2017: 126 · 2016: 88 · 2015: 120 · 2014: 124 · 2013: 134 · 2012: 113
FWCI: 83.74
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.cambridge.org/core/terms (unspecified, 4994 d)
Locations: The British Journal of Psychiatry (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5u01mh035883-17)
National Institute of Mental Health (MH35883)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
Keywords: depressive disorders, depression, global burden of disease, disability-adjusted life years, years lived with disability, depression prevalence, depression incidence, age of onset, disease duration, disability severity, public health burden
MeSH terms: Adult, Depressive Disorder, Disability Evaluation, Female, Humans, Male, Public Health, Global Health, Incidence, Prevalence, Cost of Illness, Quality-Adjusted Life Years

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