Types of Unintended Consequences Related to Computerized Provider Order Entry
Open accessAbstract
OBJECTIVE: To identify types of clinical unintended adverse consequences resulting from computerized provider order entry (CPOE) implementation. DESIGN: An expert panel provided initial examples of adverse unintended consequences of CPOE. The authors, using qualitative methods, gathered and analyzed additional examples from five successful CPOE sites. METHODS: Using a card sort method, the authors developed a categorization scheme for the 79 unintended consequences initially identified and then iteratively modified the scheme to categorize 245 additional adverse consequences resulting from fieldwork. Because the focus centered on consequences requiring prevention or remedial action, the authors did not further analyze reported unintended beneficial (positive) consequences. RESULTS: Unintended adverse consequences (UACs) fell into nine major categories (in order of decreasing frequency): 1) more/new work for clinicians; 2) unfavorable workflow issues; 3) never ending system demands; 4) problems related to paper persistence; 5) untoward changes in communication patterns and practices; 6) negative emotions; 7) generation of new kinds of errors; 8) unexpected changes in the power structure; and 9) overdependence on the technology. Clinical decision support features introduced many of these unintended consequences. CONCLUSION: Identifying and understanding the types and in some instances the causes of unintended adverse consequences associated with CPOE will enable system developers and implementers to better manage implementation and maintenance of future CPOE projects.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
7 of 26 cited sources checked · 4 supported · 0 flagged · accuracy not yet measured
- Interpretationcitation
If patient loads are not decreased temporarily during training periods, clinicians work longer hours to complete their combined electronic and clinical work.
“If their patient loads are not decreased temporarily during training periods, clinicians work longer hours to complete their combined electronic and clinical work.13”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites [13] 13. Scott JT, Rundall TG, Vogt TM, Hsu J. Kaiser Permanente's experience of implementing an electronic medical record: a qualitative study. Br Med J 2005;331(7528):1313-6. source
In “Adaptation of the organisation to the new electronic medical record environment” (p. 1314), clinicians report an additional 30–75 minutes of electronic-record work per day, and the implementation provided extra clinicians to help with the initial workload. The paper does not establish the claimed condition that patient loads were not temporarily reduced during training, or that this caused clinicians to work longer hours. (LLM, conf=0.84)
Experimental — accuracy not yet measured
- Findingcitation
Loss of efficiency from CPOE often recovers over time.
“This loss of efficiency often recovers over time.12”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites [12] 12. Overhage JM, Perkins S, Tierney WM, McDonald CJ. Controlled trial of direct physician order entry: effects on physicians' time utilization in ambulatory primary care internal medicine prac- tices. J Am Med Inform Assoc 2001;8(4):361-71. source
- Premisecitation
CPOE adoption can generate new kinds of health care-practice related errors.
“Studies have indicated that CPOE adoption can generate new kinds of health care-practice related errors, while others have described roles for CPOE in both preventing and causing medication errors.(4,20 -25 )”
Quote in the paperSubstantial claim1 of 7 sources checked- cites [4] 4. Koppel R, Metlay JP, Cohen A, et al. Role of computerized physician order entry systems in facilitating medication errors. J Am Med Inform Assoc 2005;293(10):1197-203. source
- cites [20] 20. Bates DW, Kuperman GJ, Rittenberg E, et al. A randomized trial of a computer-based intervention to reduce utilization of redun- dant laboratory tests. Am J Med 1999;106(2):144 -50. source
- cites [21] 21. Bates DW, Teich JM, Lee J, et al. The impact of computerized physician order entry on medication error prevention. J Am Med Inform Assoc 1999;6(4):313-21. source
- cites [22] 22. Bobb A, Gleason K, Husch M, Feinglass J, Yarnold PR, Noskin GA. The epidemiology of prescribing errors: the potential impact of computerized prescriber order entry. Arch Intern Med 2004;164(7):785-92. source
- cites [23] 23. Horsky J, Kuperman GJ, Patel VL. Comprehensive analysis of a medication dosing error related to CPOE. J Am Med Inform Assoc 2005;12(4):377-82. source
- cites [24] 24. Kaushal R, Shojania KG, Bates DW. Effects of computerized physician order entry and clinical decision support systems on medication safety: a systematic review. [see comment]. Arch Intern Med 2003;163(12):1409 -16. source
- cites [25] 25. Oren E, Shaffer ER, Guglielmo BJ. Impact of emerging technol- ogies on medication errors and adverse drug events. Am J Health-System Pharm 2003;60(14):1447-58. source
- Findingreasoning
CPOE systems can add to ineffective or dysfunctional workflows when CPOE developers' computational models do not reflect actual clinical practices.
“These systems can add to ineffective or dysfunctional workflows when CPOE developers' computational models do not reflect actual clinical practices.”
Quote in the paperSubstantial claim - Findingreasoning
It is difficult to reconcile old order sets with new institutional initiatives to streamline care processes and follow recent evidence-based clinical practice guidelines.
“It is also difficult to reconcile old order sets with new institutional initiatives to streamline care processes and to follow the most recent evidence-based clinical practice guidelines.”
Quote in the paperSubstantial claim
- Findingnone given
The indiscriminant, excessive generation of clinical alerts by CPOE systems can slow clinicians as they pause to decipher alerts, deliberate on whether and how to respond, and potentially document reasons for not complying with alerts.
“The indiscriminant, excessive generation of clinical alerts by CPOE systems can also slow clinicians as they pause to decipher alerts, deliberate on whether and how to respond, and potentially document reasons for not complying with alerts.”
Quote in the paperNot a substantial claim - Findingreasoning
Many CPOE implementations change or eliminate multiple interdependent steps in the ordering process, resulting in fewer process reviews and greater potential difficulties.
“Many CPOE implementations change or eliminate these multiple interdependent steps, resulting in fewer process reviews and greater potential difficulties.”
Quote in the paperSubstantial claim - Findingreasoning
CPOE adoption transforms some acute problems into subtle and insidious ones.
“CPOE adoption transforms some acute problems into subtle and insidious ones.”
Quote in the paperSubstantial claim - Findingnone given
When CPOE systems are poorly integrated with other clinical information systems, clinicians find it time-consuming to log in to different systems using different account names and passwords.
“When CPOE systems are poorly integrated with other clinical information systems, clinicians find it time-consuming to log in to different systems using different account names and passwords.”
Quote in the paperNot a substantial claim - Findingreasoning
CPOE systems may engender new work by requiring clinicians to respond to excessive alerts that may contain non-helpful information.
“(b) respond to excessive alerts that may contain non-helpful information (e.g., non-specific medication interactions with no application to the current patient);”
Quote in the paperSubstantial claim - Findingown data
In one case, automated daily chest x-ray orders went on ad infinitum until an intervention addressed it.
“Once we automated those daily chest x-ray orders, [they] went on ad infinitum until we came up with an intervention to address that.”
Quote in the paperNot a substantial claim - Findingnone given
Clinical decision support features introduced many of the unintended consequences.
“Clinical decision support features introduced many of these unintended consequences.”
Quote in the paperNot a substantial claim - Findingown data
The project team noted many instances where fewer process reviews led to problems.
“The project team noted many instances where fewer process reviews led to problems.”
Quote in the paperSubstantial claim - Findingreasoning
Overhead in maintaining systems and data increases regularly.
“Overhead in maintaining systems and data increases regularly.”
Quote in the paperSubstantial claim - Findingreasoning
In some cases, data from one system must be entered manually into another, doubling the work.
“In some cases, data from one system must be entered manually into another, doubling the work.”
Quote in the paperNot a substantial claim - Findingreasoning
When CPOE systems allow clinicians to create their own order sets, disparate single-user sets proliferate, making it progressively difficult to standardize, update, or maintain them over time.
“When CPOE systems allow clinicians to create their own order sets, disparate single-user sets proliferate.It becomes progressively difficult to standardize, update, or maintain these over time.”
Quote in the paperSubstantial claim - Findingreasoning
CPOE systems may engender new work by requiring clinicians to expend extra time in completing non-routine, complex orders.
“(c) expend extra time in completing non-routine, complex orders (e.g., selecting among differing doses and types of insulin to be administered at different times for a diabetic patient).”
Quote in the paperSubstantial claim - Findingreasoning
Clinicians complain when contention for access to computers interferes with accomplishing clinical tasks, particularly during the busiest hours.
“Clinicians complain when contention for access to computers interferes with accomplishing clinical tasks, particularly during the busiest hours (e.g., after morning rounds).”
Quote in the paperNot a substantial claim - Findingreasoning
CPOE systems may engender new work by requiring clinicians to enter new information not previously required.
“The CPOE systems may engender new work by requiring that clinicians: (a) enter new information (e.g., justification for a treatment selection) not previously required;”
Quote in the paperSubstantial claim - Findingown data
New workflows allowing clinicians to enter orders from anywhere can cause unexpected duplications or contradictions among orders, to the point of endangering patient care.
“However, such new workflows can cause unexpected duplications or contradictions among orders, to the point of endangering patient care.”
Quote in the paperSubstantial claim - Findingreasoning
System failures increasingly wreak havoc when paper backup systems are not in place.
“System failures increasingly wreak havoc when paper backup systems are not in place:”
Quote in the paperSubstantial claim - Findingreasoning
The burden on technical support staff rarely levels off.
“The burden on the technical support staff rarely levels off.”
Quote in the paperNot a substantial claim - Findingreasoning
The IT department gains power as the new enforcer of standards, even when other departments mandate the standards.
“Viewed as the new enforcer of standards, the IT department gains power, even when other departments mandate the standards.”
Quote in the paperSubstantial claim - Findingown data
Nurses were typically seen manually transcribing allergy, blood type, and medication information from the CPOE system to paper-based medication administration records.
“We typically saw nurses manually transcribing allergy, blood type, and medication information from the CPOE system to paper-based medication administration records.”
Quote in the paperSubstantial claim - Findingown data
In hospitals where CPOE systems generated and printed patient summary sheets, some providers documented patient progress notes on these printouts.
“In hospitals where CPOE systems generated and printed patient summary sheets, we noticed some providers documenting patient progress notes on these printouts.”
Quote in the paperSubstantial claim - Findingreasoning
Administration and quality assurance departments gain power by requiring users to comply with CPOE-based directives.
“Administration and quality assurance departments gain power by requiring users to comply with CPOE-based directives:”
Quote in the paperSubstantial claim - Findingreasoning
CPOE systems can exacerbate problems related to the use of verbal orders in conjunction with system entry.
“CPOE systems can exacerbate problems related to the use of verbal orders in conjunction with system entry; some institutions have gone to the extreme of banning verbal orders except in the case of emergencies:”
Quote in the paperSubstantial claim - Findingreasoning
Long, dense pick lists predispose a provider to selecting a patient name adjacent to the intended name.
“For example, long, dense pick lists predispose a provider to selecting a patient name adjacent to the intended name.”
Quote in the paperSubstantial claim - Findingnone given
Doctors, nurses and other providers consistently report that clinical systems like CPOE can cause unsatisfactory reductions in face-to-face communication regarding patient care.
“Doctors, nurses and other providers consistently report that clinical systems like CPOE can cause unsatisfactory reductions in face-to-face communication regarding patient care.”
Quote in the paperNot a substantial claim - Findingown data
Use of paper was especially pronounced when paper interfaces substituted for lack of electronic CPOE system integration with other clinical systems.
“Use was especially pronounced when paper interfaces substituted for lack of electronic CPOE system integration with other clinical systems (e.g., medication administration recording, pharmacy dispensing, or laboratory ordering).”
Quote in the paperSubstantial claim - Findingown data
Use of paper was endemic in the five institutions visited.
“Use of paper was endemic in the five institutions we visited.”
Quote in the paperSubstantial claim - Findingown data
Despite an explicit directive on CPOE printouts not to do so, and counter to current recommendations by the American Hospital Information Management Association, clinicians placed annotated printouts in the patient's chart as formal documentation.
“Despite an explicit directive on CPOE printouts not to do so, and counter to current recommendations by the American Hospital Information Management Association, 17 clinicians placed annotated printouts in the patient's chart as formal documentation.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [17] 17. AHIMA e-HIM Work Group on Health Information in a Hybrid Environment. The Complete Medical Record in a Hybrid EHR Environment. Part III. Authorship of and Printing the Health Record (AHIMA Practice Brief). Available at: http://library. ahima.org/xpedio/groups/public/documents/ahima/bok1_ 021583.hcsp?dDocNameϭbok1_021583. Accessed Apr 29, 2006.
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Findingreasoning
Paper often serves as a necessary, sometimes superior, cognitive memory aid.
“By contrast, paper often serves as a necessary, sometimes superior, cognitive memory aid.”
Quote in the paperNot a substantial claim - Findingreasoning
CPOE systems often dramatically alter traditional communication patterns among care providers, ancillary services, and clinical departments.
“CPOE systems often dramatically alter traditional communication patterns among care providers, ancillary services, and clinical departments.”
Quote in the paperSubstantial claim - Findingreasoning
Many new errors result from straightforward system interface design problems, such as dense pick lists that cause juxtaposition problems.
“Many new errors result from straightforward system interface design problems, such as dense pick lists that cause juxtaposition problems.”
Quote in the paperSubstantial claim - Findingreasoning
When many departments participate in CPOE implementation, significant unanticipated power shifts occur.
“When many departments participate in CPOE implementation, significant unanticipated power shifts occur.”
Quote in the paperSubstantial claim - Findingnone given
CPOE systems can significantly increase clinician workload.
“CPOE systems can significantly increase clinician workload, and improved system design may not reduce the amount of new work such systems require.”
Quote in the paperSubstantial claim - Findingown data
In hospitals where CPOE and ancillary system integration was incomplete, computerized orders were printed out in processing departments and then re-entered into the local department's clinical information system.
“In hospitals where CPOE and ancillary system integration was incomplete, we observed computerized orders being printed out in the processing departments, then re-entered into the local department's clinical information system.”
Quote in the paperSubstantial claim - Findingnone given
Installation of CPOE replaces the nexus of previously interpersonal conversations regarding provision of care with a computer system.
“Installation of CPOE replaces the nexus of previously interpersonal conversations regarding provision of care with a computer system.”
Quote in the paperSubstantial claim - Findingreasoning
Similar errors occur whenever pick lists facilitate selection of other order parameters.
“Similar errors occur whenever pick lists facilitate selection of other order parameters.”
Quote in the paperNot a substantial claim - Findingown data
Emergency orders were often placed in the CPOE system and also redundantly phoned in to assure immediate execution.
“We observed many instances where emergency orders were not only placed in the CPOE system but were also (redundantly) phoned in to assure they took place immediately.”
Quote in the paperSubstantial claim - Findingnone given
The amount of time a CPOE system had been in use strongly correlated with the level of positive emotions the system elicited.
“The amount of time a CPOE system had been in use strongly correlated with the level of positive emotions the system elicited.”
Quote in the paperNot a substantial claim - Findingown data
The nine types of unintended consequences emerged with surprising regularity at the sites visited.
“We found that the nine types of unintended consequences emerged with surprising regularity at the sites visited.”
Quote in the paperSubstantial claim - Findingown data
This study identified types of unintended, negative (adverse) consequences resulting from CPOE implementation.
“This study identified types of unintended, negative (adverse) consequences resulting from CPOE implementation.”
Quote in the paperSubstantial claim - Findingnone given
UACs pose significant consequences for clinicians, technical staff, and organizations as a whole.
“The UACs pose significant consequences for clinicians, technical staff, and organizations as a whole.”
Quote in the paperSubstantial claim - Findingnone given
Poorly designed alerts constantly interrupt providers, often with trivial, redundant, or already known information.
“Poorly designed alerts constantly interrupt providers, often with trivial, redundant, or already known information.”
Quote in the paperSubstantial claim - Premisecitation
Many CPOE systems slow the speed at which clinicians can carry out clinical documentation and ordering processes.
“Many CPOE systems slow the speed at which clinicians can carry out the clinical documentation and ordering processes.11”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [11] 11. Poissant L, Pereira J, Tamblyn R, Kawasumi Y. The impact of electronic health records on time efficiency of physicians and nurses: a systematic review. J Am Med Inform Assoc 2005;12(5): 505-16. source
- Premisecitation
In actual clinical practice, the clinical ordering process is much more adaptable than a predictable step sequence, and includes a variety of checks, balances, interventions, and exceptions.
“However, in actual clinical practice the process is much more adaptable, and includes a variety of checks, balances, interventions, and exceptions.14”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [14] 14. Hazlehurst B, McMullen C, Gorman PN, Sittig DF. How the ICU follows orders: Care delivery as a complex activity system. AMIA Ann Symp. 2003:284 -88.
- Interpretationreasoning
If CPOE designers have not considered the appropriate range of workflow perspectives, the resulting technological system cannot accommodate comprehensive, fully integrated clinical workflows.
“Furthermore, if CPOE designers have not considered the appropriate range of workflow perspectives (e.g., those of the nursing or clerical staff, as well as of physicians), the resulting technological system cannot accommodate comprehensive, fully integrated clinical workflows.”
Quote in the paperSubstantial claim - Premisenone given
Certain free-text fields cannot be processed by CDS components of CPOE.
“For example, certain free-text fields cannot be processed by CDS components of CPOE.”
Quote in the paperSubstantial claim - Interpretationreasoning
Depending on an individual's learning style and the type and amount of available decision support, CDS may enrich clinical training.
“Thus, depending on an individual's learning style and the type and amount of available decision support, CDS may actually enrich clinical training.”
Quote in the paperNot a substantial claim - Interpretationreasoning
Rapid and significant changes in a patient's condition in the time interval between order discussion and order entry may lead to omission or delayed entry of some relevant orders.
“Rapid and significant changes in the patient's condition in the time interval between order discussion and order entry may lead to omission or delayed entry of some relevant orders.”
Quote in the paperSubstantial claim - Interpretationreasoning
Improper data placement may impede other clinicians from finding important information.
“Furthermore, improper data placement may impede other clinicians from finding important information:”
Quote in the paperSubstantial claim - Interpretationcitation
As CPOE technology diffuses and becomes entrenched, clinical care delivery becomes inextricably dependent upon it.
“As CPOE technology diffuses and becomes entrenched within organizations, clinical care delivery becomes inextricably dependent upon it.”
Quote in the paperSubstantial claim- Rests on an assumption: Health care is increasingly dependent on technology and this is unlikely to change.
- Interpretationreasoning
No CPOE system fits all workflows of a given hospital perfectly.
“No CPOE system fits all workflows of a given hospital perfectly.”
Quote in the paperSubstantial claim - Interpretationreasoning
CPOE systems may induce changes in the power structure and culture of an organization as they enforce clinical practice patterns and monitor clinicians' behaviors.
“As CPOE systems enforce specific clinical practice patterns, while at the same time monitoring clinicians' behaviors, they may induce changes in the power structure and culture of an organization.”
Quote in the paperSubstantial claim - Interpretationreasoning
Whether the power base is centralized or decentralized plays an important role in occurrence of UACs.
“Whether the power base is centralized or decentralized plays an important role in occurrence of UACs.”
Quote in the paperSubstantial claim - Interpretationreasoning
If the system does not provide adequate feedback on who was selected, the user may proceed to enter an entire set of orders on the wrong patient.
“The system should provide adequate feedback on who was selected (e.g., displaying the selected name in large letters on the next screen).If this does not occur, the user may proceed to enter an entire set of orders on the wrong patient.”
Quote in the paperSubstantial claim - Interpretationreasoning
CPOE systems may subtly bring important power issues to the surface.
“For these reasons, CPOE systems may subtly bring important power issues to the surface.”
Quote in the paperSubstantial claim - Interpretationreasoning
Clinicians must navigate serially through CPOE interface screens to perform their work.
“Thus, clinicians must learn to navigate serially through CPOE interface screens to perform their work.”
Quote in the paperSubstantial claim- Rests on an assumption: CPOE workstation screens cannot display large amounts of clinical data simultaneously.
- Interpretationreasoning
Constraints from narrowly defined authorizations may redistribute work in unexpected ways, causing frustration.
“the constraints may also redistribute work in unexpected ways, causing frustration.”
Quote in the paperSubstantial claim - Interpretationreasoning
Poor coordination in deploying test, training, and production versions of CPOE systems can create new kinds of errors.
“Poor coordination in deploying test, training, and production versions of CPOE systems can create new kinds of errors.”
Quote in the paperSubstantial claim - Interpretationreasoning
Shifting from paper-based order generation to CPOE is bound to evoke strong emotional responses as users struggle to adapt to the new technology.
“Shifting from paper-based order generation to CPOE is bound to evoke strong emotional responses as users struggle to adapt to the new technology.”
Quote in the paperNot a substantial claim - Interpretationreasoning
Important knowledge gaps might emerge for a clinician who relied on CDS to provide real-time information or error prevention.
“Important knowledge gaps might emerge for the clinician who relied on CDS to provide real-time information and/or error prevention.”
Quote in the paperSubstantial claim
- May combine two claims. 26
- Classified as probably not a substantial claim. 12
- The quote only partly states this claim. 1
May combine two claims.
InterpretationcitationEmbedding clinical decision support within CPOE systems may increase clinician-users' access to educational material and may affect learning and retention.
“Although limited experience exists, embedding clinical decision support (CDS) within CPOE systems may increase clinician-users' access to educational material 30,31 and may affect learning and retention.32”
Quote in the paperSubstantial claim2 of 3 sources checked- cites [30] 30. Rosenbloom S, Geissbuhler A, Dupont W, et al. Effect of CPOE user interface design on user-initiated access to educational and patient information during clinical care. J Am Med Inform Assoc 2005;12(4):458 -73. source
- cites [31] 31. Bochicchio GV, Smit PA, Moore R, et al. Pilot Study of a Web-Based Antibiotic Decision Management Guide. J Am Coll Surg 2006;202(3):459 -67. source
- cites [32] 32. Knight A, Kravet S, Harper G, Leff B. The effect of computerized provider order entry on medical student clerkship experiences. J Am Med Inform Assoc 2005;12(5):554 -60. source
Citation 32 is attached to the claim that CPOE may affect learning and retention, not to the preceding claim about access to educational material. The Discussion reports that CPOE may affect medical students’ learning experiences, but the paper does not address retention or establish the effect for clinician-users generally. No page number is available in our copy. (LLM, conf=0.84)
Experimental — accuracy not yet measured
May combine two claims.
FindingcitationCPOE systems prevent some types of errors while creating or propagating new ones.
“CPOE systems prevent some types of errors while creating or propagating new ones.4,5,21,22,24,25,33,54 -61”
Quote in the paperSubstantial claim2 of 10 sources checked- cites [4] 4. Koppel R, Metlay JP, Cohen A, et al. Role of computerized physician order entry systems in facilitating medication errors. J Am Med Inform Assoc 2005;293(10):1197-203. source
- cites [5] 5. Ash JS, Berg M, Coiera E. Some unintended consequences of information technology in health care: the nature of patient care information system-related errors. J Am Med Inform Assoc 2004;11(2):104 -12. source
- cites [21] 21. Bates DW, Teich JM, Lee J, et al. The impact of computerized physician order entry on medication error prevention. J Am Med Inform Assoc 1999;6(4):313-21. source
- cites [22] 22. Bobb A, Gleason K, Husch M, Feinglass J, Yarnold PR, Noskin GA. The epidemiology of prescribing errors: the potential impact of computerized prescriber order entry. Arch Intern Med 2004;164(7):785-92. source
- cites [24] 24. Kaushal R, Shojania KG, Bates DW. Effects of computerized physician order entry and clinical decision support systems on medication safety: a systematic review. [see comment]. Arch Intern Med 2003;163(12):1409 -16. source
- cites [25] 25. Oren E, Shaffer ER, Guglielmo BJ. Impact of emerging technol- ogies on medication errors and adverse drug events. Am J Health-System Pharm 2003;60(14):1447-58. source
- cites [33] 33. Galanter WL, Polikaitis A, DiDomenico RJ. A trial of automated safety alerts for inpatient digoxin use with computerized phy- sician order entry. J Am Med Inform Assoc 2004;11(4):270 -7. source
The Abstract (page unavailable) says CPOE combined with basic clinical decision support decreases the likelihood of serious medication errors. Neither that passage nor the Discussion (page unavailable) says CPOE creates or propagates new errors; the Discussion addresses alerts that clinicians may ignore, not errors caused by CPOE. (LLM, conf=0.88)
Experimental — accuracy not yet measured - cites [54] 54. Berger RG, Kichak JP. Computerized physician order entry: helpful or harmful? J Am Med Inform Assoc 2004;11(2):100 -3. source
- cites [55] 55. Hagland M. Safe ways. Hospitals looking to improve patient safety are turning to CPOE, bar coding and e-prescribing. Healthcare Inform 2004;21(8):20 -5.
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites [56] 56. King WJ, Paice N, Rangrej J, Forestell GJ, Swartz R. The effect of computerized physician order entry on medication errors and adverse drug events in pediatric inpatients. Pediatrics 2003; 112(3 Pt 1):506 -9. source
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
FindingreasoningImplementation of CPOE requires advanced hardware platforms that can support clinical software, and purchasing or upgrading hardware is an ongoing need.
“Implementation of CPOE requires advanced hardware platforms that can support clinical software.Purchasing or upgrading hardware is not a one-time event, as future technology advances make this an ongoing need.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing). May combine two claims.
FindingreasoningAll employees must be trained in system use and retrained after substantive system changes.
“All employees must be trained in system use, and retrained after substantive system changes.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Findingnone givenAs clinical software systems increase in scope and capabilities, more users require more computer access time via more computers.
“As clinical software systems increase in scope and capabilities, more users require more computer access time, via more computers.”
Quote in the paperNot a substantial claimMay combine two claims.
FindingreasoningWhen the system fails to support all the individual role-players who must interact with it, work-shifting to others may occur, leading to resentment and ineffective work activity synchronization.
“When the system fails to support all the individual role-players who must interact with it, work-shifting to others may occur, leading to resentment and ineffective work activity synchronization.”
Quote in the paperSubstantial claimMay combine two claims.
FindingreasoningAfter go-live, ongoing work begins: the system must be tuned, upgraded, tested, interfaced, and backed up regularly.
“But after go-live, ongoing work begins.The system must be tuned, upgraded, tested, interfaced with other systems, and backed up regularly.”
Quote in the paperSubstantial claimMay combine two claims.
FindingreasoningNever-ending system demands arise regarding hardware and software purchases, implementation tasks, and maintenance issues, and represent UACs from the perspective of both administration and IT staff.
“Never-ending system demands arise regarding hardware and software purchases, implementation tasks, and maintenance issues.They represent UACs from the perspective of both administration and IT staff.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S2 (checkable).
FindingreasoningSoftware application demands are never-ending.
“Software application demands are also never-ending.”
Quote in the paperNot a substantial claimMay combine two claims. The quote only partly states this claim.
Findingown dataUnintended adverse consequences (UACs) of CPOE fall into nine major categories, in order of decreasing frequency: more/new work for clinicians; unfavorable workflow issues; never ending system demands; problems related to paper persistence; untoward changes in communication patterns and practices; negative emotions; generation of new kinds of errors; unexpected changes in the power structure; and,
“Unintended adverse consequences (UACs) fell into nine major categories (in order of decreasing frequency): 1) more/new work for clinicians; 2) unfavorable workflow issues; 3) never ending system demands; 4) problems related to paper persistence; 5) untoward changes in communication patterns and practices; 6) negative emotions; 7) generation of new kinds of errors; 8) unexpected changes in the”
Quote in the paperSubstantial claim- Rests on an assumption: The five selected hospitals are representative of successful CPOE implementations, so the UACs observed there generalize to other successful CPOE sites.
- Rests on an assumption: The frequency of occurrence of UAC types in the data (Table 2) accurately reflects their relative frequency in CPOE implementations.
- Rests on an assumption: The UACs observed are caused by CPOE rather than other organizational changes or site-specific factors.
- Rests on an assumption: The perspectives of clinical end-users, IT staff, and administrators are sufficient to identify the major types of UACs.
May combine two claims.
Findingnone givenAdministrators and researchers commonly leverage CPOE to collect information not directly related to patient care, and the time burden for doing so usually falls on clinicians.
“Administrators and researchers commonly leverage CPOE to collect information not directly related to patient care.The time burden for doing so usually falls on clinicians.”
Quote in the paperNot a substantial claimMay combine two claims.
FindingreasoningAs clinical staff increasingly depends on the technology, pressure to keep the system operational 24x7x365 increases, and round-the-clock help-desk support becomes necessary.
“As the clinical staff increasingly depends on the technology for their daily work, pressure to keep the system operational 24ϫ7ϫ365 increases.Roundthe-clock help-desk support becomes necessary.”
Quote in the paperSubstantial claimMay combine two claims.
FindingreasoningProviders suggest that reduction in communication increases the likelihood of errors due to miscommunication, delayed initiation and execution of orders, and fewer team-wide discussions regarding planning and coordination of care.
“The providers further suggest that reduction in communication increases the likelihood of errors due to miscommunication, delayed initiation and execution of orders, and fewer team-wide discussions regarding planning and coordination of care.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataPhysicians report loss of professional autonomy when CPOE systems prevent them from ordering preferred tests or medications, force compliance with guidelines, or limit narrative flexibility.
“Physicians report loss of professional autonomy when CPOE systems prevent them from ordering the types of tests or medications they prefer, or force them to comply with clinical guidelines they may not embrace, or limit their narrative flexibility through structured rather than free-text clinical documentation.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataClinical decision support generates a disproportionately large number, over 25%, of UACs, spanning all 9 types.
“During analysis of unintended consequences, the researchers learned that clinical decision support generates a disproportionately large number (over 25%) of UACs, spanning all 9 types above.”
Quote in the paperSubstantial claimMay combine two claims.
FindingcitationCPOE-based CDS is not consistently useful for clinicians, is impractical to maintain, and is less than fully reliable in complex situations.
“Accordingly, CPOE-based CDS is not consistently useful for clinicians, is impractical to maintain, and is less than fully reliable in complex situations.19,24,[33][34][35][36][37][38]”
Quote in the paperSubstantial claim0 of 1 sources checked- cites 19,24,[33][34][35][36][37][38]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
May combine two claims.
FindingreasoningSystem designs (including poor data organization, data omissions, etc.) and end-user confusion about system functionality contribute to new forms of errors.
“System designs (including poor data organization, data omissions, etc.), and end-user confusion about system functionality contribute to new forms of errors.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataUACs occur during all CPOE implementations, though not all institutions experience all of the types of UACs.
“First, UACs occur during all CPOE implementations, though not all institutions experience all of the types of UACs.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataThe project identified hundreds of UACs and grouped them into nine categories.
“The project identified hundreds of UACs and grouped them into nine categories.”
Quote in the paperSubstantial claimMay combine two claims.
Findingnone givenAlthough consequences of CPOE can be anticipated, their extent is typically underestimated.
“Although these consequences can be anticipated, their extent is typically underestimated.”
Quote in the paperNot a substantial claimMay combine two claims.
FindingreasoningProlonged system failures lasting hours can halt the flow of clinical information so that outpatient activities may be curtailed or canceled and emergency rooms at trauma centers may divert admissions until vital systems are restored.
“Prolonged system failures (lasting hours) can so dramatically halt the flow of clinical information that outpatient activities may be curtailed or canceled and emergency rooms at trauma centers may divert admissions until vital systems are restored.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
FindingreasoningBackup systems must operate if the primary system fails.
“Backup systems must operate if the primary system fails.”
Quote in the paperNot a substantial claimMay combine two claims.
FindingreasoningNew CPOE-related errors result from problematic electronic data presentations, confusing order option presentations and selection methods, inappropriate text entries, misunderstandings related to test, training, and production versions of the system, and workflow process mismatches.
“New CPOE-related errors result from: problematic electronic data presentations; confusing order option presentations and selection methods; inappropriate text entries; misunderstandings related to test, training, and production versions of the system; and workflow process mismatches.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataProviders used paper for temporary, handwritten data storage for later entry into the computer and as a portable, disposable, computer output display medium for quick reference.
“We observed providers using paper for temporary, handwritten data storage for later entry into the computer and conversely as a portable, disposable, computer output display medium for quick reference use during their workdays.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S4 (based). May combine two claims.
Findingnone givenAs a CPOE system evolves, users rely more completely on the software and demand ever more sophisticated functionality for clinical support.
“As a CPOE system evolves, users rely more completely on the software and demand ever more sophisticated functionality for clinical support.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataA wide variety of emotional responses to CPOE were noted, including both strongly negative and highly positive emotions, with negative comments predominating.
“We noted a wide variety of emotional responses to CPOE, including both strongly negative and highly positive emotions.Negative comments predominated.”
Quote in the paperNot a substantial claimMay combine two claims.
FindingreasoningAlerts present a major workflow process issue, adding to the steps required to enter an order.
“Alerts present a major workflow process issue, adding to the steps required to enter an order.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Findingnone givenNot all types of UACs may occur with every CPOE implementation.
“Not all types of UACs may occur with every CPOE implementation.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S4 (based).
Findingnone givenMost often it is the physician who loses power in CPOE-related power changes.
“Most often it is the physician who loses power: this must be recognized and dealt with explicitly during the CPOE planning process.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingnone givenClinicians report inappropriate alerts as highly frustrating nuisances.
“Clinicians report inappropriate alerts as highly frustrating nuisances.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing), S4 (based).
InterpretationreasoningWhenever there are adjustments, there will be unintended consequences.
“Whenever there are adjustments, there will be unintended consequences.”
Quote in the paperNot a substantial claimMay combine two claims.
InterpretationreasoningPaper-based clinical record storage will become obsolete, but use of paper in the clinical setting will not.
“Paper-based clinical record storage will become obsolete, but use of paper in the clinical setting will not.”
Quote in the paperSubstantial claim- Rests on an assumption: Paper remains the most malleable, flexible, and easily transportable data medium available.
May combine two claims.
InterpretationreasoningOrder standardization may confuse clinicians and forced awkward terminology may compromise patient care.
“While order standardization may benefit the organization, it may confuse clinicians.”
- Also stated in: § CPOE system configurations control who may do what (and when) through the use of clinical, role-based authorizations. · hedged
“Such terminology not only disrupts clinicians' workflows, but might also compromise patient care.”
Quote in the paperSubstantial claim- Also stated in: § CPOE system configurations control who may do what (and when) through the use of clinical, role-based authorizations. · hedged
Classified as probably not a substantial claim.
Interpretationnone givenUACs are the result of a constellation of factors.
“It is important to view UACs as the result of a constellation of factors.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Interpretationnone givenBuilding and maintaining an appropriate set of CPOE alerts based on an up-to-date evidence base is an onerous, never-ending task.
“Building and maintaining an appropriate set of CPOE alerts based on an up-to-date evidence base is an onerous, never-ending task.”
Quote in the paperNot a substantial claim
The paper relies on this without support.
The five selected hospitals are representative of successful CPOE implementations, so the UACs observed there generalize to other successful CPOE sites.
“The initial expert panel helped the authors to identify five hospitals in three different organizations where successful CPOE implementation occurred (See Table 1).To study a range of successful CPOE implementations, the project selected both academic and non-academic hospitals of differing sizes and geographic locations.”
The paper relies on this without support.
The frequency of occurrence of UAC types in the data (Table 2) accurately reflects their relative frequency in CPOE implementations.
“Table 2 lists the UACs and their frequencies of occurrence.”
The paper relies on this without support.
The UACs observed are caused by CPOE rather than other organizational changes or site-specific factors.
“To identify types of clinical unintended adverse consequences resulting from computerized provider order entry (CPOE) implementation.”
The paper relies on this without support.
The perspectives of clinical end-users, IT staff, and administrators are sufficient to identify the major types of UACs.
“Specifically, we gathered perspectives regarding CPOE from three groups: clinical end-users, IT staff, and administrators.”
The paper relies on this without support.
Paper remains the most malleable, flexible, and easily transportable data medium available.
“Furthermore, paper remains the most malleable, flexible, and easily transportable data medium available.”
The paper relies on this without support.
CPOE workstation screens cannot display large amounts of clinical data simultaneously.
“However, CPOE workstation screens cannot display large amounts of data simultaneously.”
The paper relies on this without support.
Health care is increasingly dependent on technology and this is unlikely to change.
“Health care is increasingly dependent on technology and this is unlikely to change.”
The paper relies on this without support.
Emotional responses to change are inevitable.
“Emotional responses to change are inevitable.”
The paper relies on this without support.
Currently, CPOE technology is immature and rapidly evolving.
“Currently, CPOE technology is immature and rapidly evolving.”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Some CDSSs are highly sophisticated, well developed, and extensively evaluated, but they tend to come from a small number of internationally recognized medical informatics institutions.
“Some CDSSs are highly sophisticated, well developed and evaluated extensively, however they tend to come from a small number of institutions recognized internationally for their work in medical informatics.19 20 30 32 33 44 -46 66”
From Computerized clinical decision support for prescribing: provision does not guarantee uptake (2010) · cites this paper as [30]
The fifth study found that 31% of physicians and 56% of nurses thought the EHR improved overall care.
“The fifth study found that only thirty-one percent of physicians and fifty-six percent of nurses believed that the EHR contributed to improvement of care overall.25”
From EHR Safety: The Way Forward to Safe and Effective Systems (2008) · cites this paper as [25]
Only five studies have examined overall safety and effectiveness.
“Although some measures of error showed improvement, overall safety and effectiveness have been addressed in only five studies.[21][22][23][24][25]”
From EHR Safety: The Way Forward to Safe and Effective Systems (2008) · cites this paper as [25]
Computerized information systems themselves can lead to unintended errors including those that involve communication processes.
“For instance, computerized information systems themselves can lead to unintended errors including those that involve communication processes.25,34,42”
From Reducing Diagnostic Errors through Effective Communication: Harnessing the Power of Information Technology (2008) · cites this paper as [42]
IT-based interventions alone cannot assure improvements in communication.
“IT-based interventions alone, however, cannot assure improvements in communication.”
From Reducing Diagnostic Errors through Effective Communication: Harnessing the Power of Information Technology (2008) · cites this paper as [42]
Research on clinical information systems repeatedly finds that CPOE integration fundamentally alters how clinicians coordinate and collaborate in care delivery.
“one theme consistently emerges: embedding CPOE in healthcare fundamentally changes the way clinicians coordinate their work activities and collaborate to deliver care.[18][19][20][21]”
From Computerized Provider Order Entry Adoption: Implications for Clinical Workflow (2009) · cites this paper as [18]
A sociotechnical framework treats activities, technologies, environments, people, and organizations as one work system that must be studied together.
“A sociotechnical evaluation framework 18,[23][24][25] views these five components of clinical work as a single work system; that is, the components cannot be effectively analyzed in isolation.”
From Computerized Provider Order Entry Adoption: Implications for Clinical Workflow (2009) · cites this paper as [18]
The authors' earlier research found nine broad types of unintended CPOE consequences, with workflow impact being the most common theme.
“in our prior work we identified nine broad categories of unintended adverse consequences related to CPOE, negative impact on workflow emerged as the most frequently occurring theme.18,22”
From Computerized Provider Order Entry Adoption: Implications for Clinical Workflow (2009) · cites this paper as [18]
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- Authors
- Campbell, E. M., Sittig, D. F., Ash, J. S., Guappone, K. P., & Dykstra, R. H.
- Affiliations
- Oregon Health & Science University (US)
- Corresponding author
- Campbell, E. M.
- Venue
- Journal of the American Medical Informatics Association
- Publisher
- Oxford University Press (OUP)
- Published
- 2006-09-01
- Volume
- 13
- Issue
- 5
- Pages
- 547-556
- ISSN
- 1067-5027 (ISSN-L)
- 1527-974X
- PMC
- PMC1561794
- OpenAlex
- W2160382101
- Semantic Scholar
- 90391845572d1d2d9424cddcbdfdb4867be5e69c
- Cited by
- 823
- References
- 61
- Citations by year
- 2026: 9 · 2025: 18 · 2024: 24 · 2023: 29 · 2022: 29 · 2021: 27 · 2020: 27 · 2019: 59 · 2018: 32 · 2017: 44 · 2016: 48 · 2015: 48 · 2014: 52 · 2013: 80 · 2012: 46
- FWCI
- 86.07
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of the American Medical Informatics Association (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- U.S. Public Health Service (ASMM10031)
- U.S. National Library of Medicine (R01LM006942, LM06942, R56LM006942)
- Topics
- Health Sciences › Health Professions › Health Information Management › Electronic Health Records Systems
- Social Sciences › Sociology and Political Science › Information Systems Theories and Implementation
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Technology and Human Factors in Education and Health
- Keywords
- computerized physician order entry, clinical workflow, clinical decision support, clinician workload, communication patterns, medical errors, health information technology implementation
- MeSH terms
- Communication, Humans, Organizational Innovation, Organizational Culture, Workload, Medical Errors, Medical Order Entry Systems
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