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Cited by 366

The DOI matches its Crossref record; 73 of the 73 references it cites were found in a registry or an index.

Potentially Curable Pancreatic Cancer: American Society of Clinical Oncology Clinical Practice Guideline

Khorana, Alok A., Mangu, Pamela B., Berlin, Jordan, Engebretson, Anitra, Hong, Theodore S., Maitra, Anirban, Mohile, Supriya G., Mumber, Matthew, Schulick, Richard, Shapiro, Marc, Urba, Susan, Zeh, Herbert J., Katz, Matthew H.G.·2016·Journal of Clinical Oncology

Abstract

Purpose: To provide evidence-based recommendations to oncologists and others on potentially curative therapy for patients with localized pancreatic cancer. Methods: ASCO convened a panel of medical oncology, radiation oncology, surgical oncology, palliative care, and advocacy experts and conducted a systematic review of literature from January 2002 to June 2015. Outcomes included overall survival, disease-free survival, progression-free survival, and adverse events. Results: Nine randomized controlled trials met the systematic review criteria. Recommendations: A multiphase computed tomography scan of the abdomen and pelvis or magnetic resonance imaging should be performed for all patients to assess the anatomic relationships of the primary tumor and for the presence of intra-abdominal metastases. Baseline performance status, comorbidity profile, and goals of care should be evaluated and established. Primary surgical resection is recommended for all patients who have no metastases, appropriate performance and comorbidity profiles, and no radiographic interface between primary tumor and mesenteric vasculature. Preoperative therapy is recommended for patients who meet specific characteristics. All patients with resected pancreatic cancer who did not receive preoperative therapy should be offered 6 months of adjuvant chemotherapy in the absence of contraindications. Adjuvant chemoradiation may be offered to patients who did not receive preoperative therapy with microscopically positive margins (R1) after resection and/or who had node-positive disease after completion of 4 to 6 months of systemic adjuvant chemotherapy. Patients should have a full assessment of symptoms, psychological status, and social supports and should receive palliative care early. Patients who have completed treatment and have no evidence of disease should be monitored. Additional information is available at www.asco.org/guidelines/PCPC and www.asco.org/guidelineswiki .

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Metadata

Authors
Khorana, A. A., Mangu, P. B., Berlin, J., Engebretson, A., Hong, T. S., Maitra, A., Mohile, S. G., Mumber, M., Schulick, R., Shapiro, M., Urba, S., Zeh, H. J., & Katz, M. H. G.
Venue
Journal of Clinical Oncology
Published
2016-07-20
Volume
34
Issue
21
Pages
2541-2556
ISSN
  • 0732-183X (ISSN-L)
  • 1527-7755
OpenAlex
W2416383077
Cited by
366
References
73
FWCI
22.87
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Potentially Curable Pancreatic Cancer: American Society of Clinical Oncology Clinical Practice Guideline. https://app.cochat.ai/papers/10.1200/jco.2016.67.5553
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Khorana, A. A., Mangu, P. B., Berlin, J., Engebretson, A., Hong, T. S., Maitra, A., Mohile, S. G., Mumber, M., Schulick, R., Shapiro, M., Urba, S., Zeh, H. J., & Katz, M. H. G. (2016). Potentially Curable Pancreatic Cancer: American Society of Clinical Oncology Clinical Practice Guideline. Journal of Clinical Oncology. https://doi.org/10.1200/jco.2016.67.5553

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.