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Cell Biology by the Numbers
Open accessAbstract
A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid
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Cited by
Greenwald, N. F., Miller, G., Moen, E., Kong, A., Kagel, A., Dougherty, T., Fullaway, C. C., McIntosh, B. J., Leow, K. X., Schwartz, M. S., et al. (2022) · Nature Biotechnology · doi:10.1038/s41587-021-01094-0 · Cited by 953
Mayr, C. (2019) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a034728 · Cited by 519
Reconstructing organisms in silico: genome-scale models and their emerging applications
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Root of the Tree: The Significance, Evolution, and Origins of the Ribosome
Bowman, J. C., Petrov, A. S., Frenkel-Pinter, M., Penev, P. I., & Williams, L. D. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.9b00742 · Cited by 197
Molecular Mechanisms for Bacterial Potassium Homeostasis
Stautz, J., Hellmich, Y., Fuss, M. F., Silberberg, J. M., Devlin, J. R., Stockbridge, R. B., & Hänelt, I. (2021) · Journal of Molecular Biology · doi:10.1016/j.jmb.2021.166968 · Cited by 189
Gorin, G., Fang, M., Chari, T., & Pachter, L. (2022) · PLOS Computational Biology · doi:10.1371/journal.pcbi.1010492 · Cited by 186
Sustained enzymatic activity and flow in crowded protein droplets
Testa, A., Dindo, M., Rebane, A. A., Nasouri, B., Style, R. W., Golestanian, R., Dufresne, E. R., & Laurino, P. (2021) · Nature Communications · doi:10.1038/s41467-021-26532-0 · Cited by 144
RNA polymerases as moving barriers to condensin loop extrusion
Brandão, H. B., Paul, P., van den Berg, A. A., Rudner, D. Z., Wang, X., & Mirny, L. A. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1907009116 · Cited by 143
“Although the size of isolated eukaryotic RNAPs are comparable to their bacterial counterparts [ ∼ 10 – 15 nm in diameter (56)], sizes of whole elongating transcription complexes in eukaryotes can be considerably larger.”
Na, K., Shin, S., Lee, H., Shin, D., Baek, J., Kwak, H., Park, M., Shin, J., & Hyun, J. (2018) · Journal of Industrial and Engineering Chemistry · doi:10.1016/j.jiec.2017.12.032 · Cited by 117
Stochastic motion and transcriptional dynamics of pairs of distal DNA loci on a compacted chromosome
Brückner, D. B., Chen, H., Barinov, L., Zoller, B., & Gregor, T. (2023) · Science · doi:10.1126/science.adf5568 · Cited by 112
Evolutionary transitions in learning and cognition
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Translation fidelity coevolves with longevity
Ke, Z., Mallik, P., Johnson, A. B., Luna, F., Nevo, E., Zhang, Z. D., Gladyshev, V. N., Seluanov, A., & Gorbunova, V. (2017) · Aging Cell · doi:10.1111/acel.12628 · Cited by 82
Water and Life: The Medium is the Message
Frenkel-Pinter, M., Rajaei, V., Glass, J. B., Hud, N. V., & Williams, L. D. (2021) · Journal of Molecular Evolution · doi:10.1007/s00239-020-09978-6 · Cited by 71
The correlation between cell and nucleus size is explained by an eukaryotic cell growth model
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Population-based heteropolymer design to mimic protein mixtures
Ruan, Z., Li, S., Grigoropoulos, A., Amiri, H., Hilburg, S. L., Chen, H., Jayapurna, I., Jiang, T., Gu, Z., Alexander-Katz, A., et al. (2023) · Nature · doi:10.1038/s41586-022-05675-0 · Cited by 64
Autophagy adaptors mediate Parkin-dependent mitophagy by forming sheet-like liquid condensates
Yang, Z., Yoshii, S. R., Sakai, Y., Zhang, J., Chino, H., Knorr, R. L., & Mizushima, N. (2024) · The EMBO Journal · doi:10.1038/s44318-024-00272-5 · Cited by 47
Homeostasis in the Central Dogma of molecular biology: the importance of mRNA instability
Pérez-Ortín, J. E., Tordera, V., & Chávez, S. (2019) · RNA Biology · doi:10.1080/15476286.2019.1655352 · Cited by 35
Fundamental constraints to the logic of living systems
Solé, R., Kempes, C. P., Corominas-Murtra, B., De Domenico, M., Kolchinsky, A., Lachmann, M., Libby, E., Saavedra, S., Smith, E., & Wolpert, D. (2024) · Interface Focus · doi:10.1098/rsfs.2024.0010 · Cited by 34
Kögler, M., Itkonen, J., Viitala, T., & Casteleijn, M. G. (2020) · Scientific Reports · doi:10.1038/s41598-020-59091-3 · Cited by 29
Kinetic modeling of the genetic information processes in a minimal cell
Thornburg, Z. R., Melo, M. C. R., Bianchi, D., Brier, T. A., Crotty, C., Breuer, M., Smith, H. O., Hutchison, C. A., Glass, J. I., & Luthey-Schulten, Z. (2019) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2019.00130 · Cited by 22
Spiers Memorial Lecture: Quantum chemistry, classical heuristics, and quantum advantage
Chan, G. K.-L. (2024) · Faraday Discussions · doi:10.1039/d4fd00141a · Cited by 20
Resource allocation in mammalian systems
Baghdassarian, H. M., & Lewis, N. E. (2024) · Biotechnology Advances · doi:10.1016/j.biotechadv.2023.108305 · Cited by 17
Unfolding and identification of membrane proteins in situ
Galvanetto, N., Ye, Z., Marchesi, A., Mortal, S., Maity, S., Laio, A., & Torre, V. (2022) · eLife · doi:10.7554/elife.77427 · Cited by 13
Glycolysis model shows that allostery maintains high ATP and limits accumulation of intermediates
Choe, M., Einav, T., Phillips, R., & Titov, D. V. (2025) · Biophysical Journal · doi:10.1016/j.bpj.2025.03.037 · Cited by 13
Self-citationData mining for traffic information
Clague, M. J., & Urbé, S. (2020) · Traffic · doi:10.1111/tra.12702 · Cited by 6
Biological processes as exploratory dynamics
Kondev, J., Kirschner, M., Garcia, H. G., Salmon, G. L., & Phillips, R. (2026) · Biophysical Journal · doi:10.1016/j.bpj.2025.09.009 · Cited by 4
Self-citationHomeostasis in the Central Dogma of Molecular Biology: the importance of mRNA instability
Pérez-Ortín, J. E., Tordera, V., & Chávez, S. (2019) · doi:10.1101/599050 · Cited by 1
Metadata
- Authors
- Milo, R., & Phillips, R.
- Venue
- Garland Science eBooks
- Publisher
- Garland Science
- Published
- 2015-12-07
- OpenAlex
- W2785199982
- Cited by
- 1,014
- References
- 0
- FWCI
- 42.79
- Type
- book
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.