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Beige Fat, Adaptive Thermogenesis, and Its Regulation by Exercise and Thyroid Hormone

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Fibroblast growth Factor-21 promotes ketone body utilization in neurons through activation of AMP-dependent kinase

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Impact of adipokines and myokines on fat browning

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A Brain-Melanocortin-Vagus Axis Mediates Adipose Tissue Expansion Independently of Energy Intake

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Fibroblast growth factor 21 and autophagy: A complex interplay in Parkinson disease

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Levels of β-klotho determine the thermogenic responsiveness of adipose tissues: involvement of the autocrine action of FGF21

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Adapting to the cold: A role for endogenous fibroblast growth factor 21 in thermoregulation?

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Sensing and signaling mechanisms linking dietary methionine restriction to the behavioral and physiological components of the response

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Hepatic Phospholipid Remodeling Modulates Insulin Sensitivity and Systemic Metabolism

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MANF in POMC Neurons Promotes Brown Adipose Tissue Thermogenesis and Protects Against Diet-Induced Obesity

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A low-protein, high-carbohydrate diet increases browning in perirenal adipose tissue but not in inguinal adipose tissue

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FGF21 Induces Skeletal Muscle Atrophy and Increases Amino Acids in Female Mice: A Potential Role for Glucocorticoids

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Endocrine Fibroblast Growth Factors in Relation to Stress Signaling

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Nutritional regulation of fibroblast growth factor 21: from macronutrients to bioactive dietary compounds

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Roux-en-Y gastric bypass surgery is effective in fibroblast growth factor-21 deficient mice

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Hormonal factors in the control of the browning of white adipose tissue

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A pyrexic effect of FGF21 independent of energy expenditure and UCP1

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The autocrine role of FGF21 in cultured adipocytes

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Fibroblast growth factor 21: A “rheostat” for metabolic regulation?

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Hepatoprotective effects of the long-acting fibroblast growth factor 21 analog PF-05231023 in the GAN diet-induced obese and biopsy-confirmed mouse model of nonalcoholic steatohepatitis

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The Pan-liver Network Theory

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Prolonged FGF21 treatment increases energy expenditure and induces weight loss in obese mice independently of UCP1 and adrenergic signaling

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Whole-body and adipose tissue-specific mechanisms underlying the metabolic effects of fibroblast growth factor 21 in the Siberian hamster

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Brown adipose tissue lipoprotein and glucose disposal is not determined by thermogenesis in uncoupling protein 1-deficient mice

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Adipose-specific ablation of Nrf2 transiently delayed high-fat diet-induced obesity by altering glucose, lipid and energy metabolism of male mice.

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Effects of Fibroblast Growth Factor 21 on Lactate Uptake and Usage in Mice with Diabetes-Associated Cognitive Decline

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Alcohol, White Adipose Tissue, and Brown Adipose Tissue: Mechanistic Links to Lipogenesis and Lipolysis

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Spermidine activates adipose tissue thermogenesis through autophagy and fibroblast growth factor 21

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Hormonal and nutritional signalling in the control of brown and beige adipose tissue activation and recruitment

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FGF21 decreases food intake and body weight in obese Göttingen minipigs

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Phosphorylation of RXRα mediates the effect of JNK to suppress hepatic FGF21 expression and promote metabolic syndrome

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Fibroblast Growth Factor 21-Null Mice Do Not Exhibit an Impaired Response to Fasting

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Glucagon and energy expenditure; Revisiting amino acid metabolism and implications for weight loss therapy

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Exploring endocrine FGFs - structures, functions and biomedical applications

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FGF21 mediating the Sex-dependent Response to Dietary Macronutrients

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Nobiletin and 3′-Demethyl Nobiletin Activate Brown Adipocytes upon β-Adrenergic Stimulation

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ATF4 expression in thermogenic adipocytes is required for cold-induced thermogenesis in mice via FGF21-independent mechanisms

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GLP-1R/GCGR dual agonism dissipates hepatic steatosis to restore insulin sensitivity and rescue pancreatic β-cell function in obese male mice

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Innate immunity orchestrates adipose tissue homeostasis

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Prolonged Chronic Stress and Persistent Iron Dysregulation Prevent Anemia Recovery Following Trauma

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Whole transcriptome analysis and validation of metabolic pathways in subcutaneous adipose tissues during FGF21-induced weight loss in non-human primates

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The Possible Role of Metformin and Fibroblast Growth Factor‐21 in Multiple Sclerosis Neuropathology: Birds of a Feather Flock Together

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Beyond obesity – thermogenic adipocytes and cardiometabolic health

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Reduced adiposity attenuates FGF21 mediated metabolic improvements in the Siberian hamster

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Adrenergic receptor-mediated activation of FGF-21-adiponectin axis exerts atheroprotective effects in brown adipose tissue-transplanted apoE mice

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Endocrine FGFs and their signaling in the brain: Relevance for energy homeostasis

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FGF21 contributes to metabolic improvements elicited by combination therapy with exenatide and pioglitazone in patients with type 2 diabetes

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Amino acids contribute to adaptive thermogenesis. New insights into the mechanisms of action of recent drugs for metabolic disorders are emerging

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Circulating fibroblast growth factor 21 is reduced, whereas its production is increased in a fat depot-specific manner in cold-acclimated rats

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Biology of Stress Responses in Aging

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The Sweetest Thing: Regulation of Macronutrient Preference by FGF21

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ATF4-dependent and independent mitokine secretion from OPA1 deficient skeletal muscle in mice is sexually dimorphic

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Dietary Essential Amino Acid Restriction Promotes Hyperdipsia via Hepatic FGF21

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IUPHAR review: From foe to friend: Repurposing glucagon to treat obesity and type 2 diabetes

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Liver-Specific Nonviral Gene Delivery of Fibroblast Growth Factor 21 Protein Expression in Mice Regulates Body Mass and White/Brown Fat Respiration

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FGF21 protects against ischaemia reperfusion injury in normal and fatty livers

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The effects of selective beta-adrenergic blockade on bone marrow dysfunction following severe trauma and chronic stress

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Effects of central FGF21 infusion on the glucose homeostasis in rats (brain–pancreas axis)

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Circulating molecules that control brown/beige adipocyte differentiation and thermogenic capacity

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Reducing branched‐chain amino acid intake to reverse metabolic complications in obesity and type 2 diabetes

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New insights and advances of sodium-glucose cotransporter 2 inhibitors in heart failure

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Cross-Talk Between Signaling and Transcriptional Networks Regulating Thermogenesis—Insights into Canonical and Non-Canonical Regulatory Pathways

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Animal Models for Manipulation of Thermogenesis

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Bibliometric analysis of fibroblast growth factor 21 research over the period 2000 to 2021

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FGF-21 Conducts a Liver-Brain-Kidney Axis to Promote Renal Cell CarcinomaPreprint

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Fenofibrate treatment during lactation prevents liver and adipose tissue associated metabolic dysfunction in a rat model of childhood obesity

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FGF21 acting on the noradrenergic nervous system protects against influenza virus infection

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FGF21 signals through hindbrain neurons to alter food intake and energy expenditure during dietary protein restriction

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FGF21 Levels in Pheochromocytoma/Functional Paraganglioma

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Fluctuations of serum fibroblast growth factor-21 levels in prolonged fasting in male adults

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The role of increased FGF21 in VLDL-TAG secretion and thermogenic gene expression in mice under protein malnutrition

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