Cited by 167Hormonal and reproductive studiesAdrenal Hormones and DisordersSperm and Testicular Function

The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.

Correlates of Low Testosterone and Symptomatic Androgen Deficiency in a Population-Based Sample

Open access

Hall, Susan A., Esche, Gretchen R., Araujo, Andre B., Travison, Thomas G., Clark, Richard V., Williams, Rachel E., McKinlay, John B.·2008·The Journal of Clinical Endocrinology & Metabolism

DOI 10.1210/jc.2008-0021PMC PMC2579652

Open this paper in CoChat — free account Open PDF

Abstract

CONTEXT: Risk factors for low testosterone and symptomatic androgen deficiency (AD) may be modifiable. OBJECTIVE: Our objective was to examine demographic, anthropometric, and medical correlates of low testosterone and symptomatic AD. DESIGN: Data were used from the Boston Area Community Health Survey, an epidemiological study conducted from 2002-2005. SETTING: Data were obtained from a community-based random sample of racially and ethnically diverse men. PATIENTS OR OTHER PARTICIPANTS: Data were available for 1822 men. MAIN OUTCOME MEASURES: Multivariate logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals (CI) for associations of covariates with 1) low testosterone and 2) symptomatic AD. The operational definition of low testosterone was serum total testosterone less than 300 ng/dl and free testosterone less than 5 ng/dl; symptomatic AD was defined as the additional presence of symptoms: any of low libido, erectile dysfunction, or osteoporosis or two or more of sleep disturbance, depressed mood, lethargy, or diminished physical performance. RESULTS: Factors associated with low testosterone included age (OR = 1.36; 95% CI= 1.11-1.66, per decade), low per-capita income ($6000 or less per household member vs. more than $30,000; OR = 2.86; 95% CI = 1.39-5.87), and waist circumference (per 10-cm increase; OR = 1.75; 95% CI = 1.45-2.12). Only age (OR = 1.36; 95% CI = 1.04-1.77), waist circumference (OR = 1.88; 95% CI = 1.44-2.47), and health status (OR = 0.21; 95% CI = 0.05-0.92, excellent vs. fair/poor) were associated with our construct of symptomatic AD. Of all variables, waist circumference was the most important contributor in both models. CONCLUSIONS: Waist circumference is a potentially modifiable risk factor for low testosterone and symptomatic AD. Manifestation of symptoms may be a consequence of generally poor health status.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1210/jc.2008-0021

Cites

38 of 38 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Applied logistic regression
(1990) · Choice Reviews Online · doi:10.5860/choice.27-3338 · Cited by 35,305
A 12-Item Short-Form Health Survey: Construction of Scales and Preliminary Tests of Reliability and Validity
WARE, J. E., KOSINSKI, M., & KELLER, S. D. (1996) · Medical Care · doi:10.1097/00005650-199603000-00003 · Cited by 17,392
Analysis of Incomplete Multivariate Data
Booth, D. E., & Schafer, J. L. (2000) · Technometrics · doi:10.2307/1271466 · Cited by 5,627
A Critical Evaluation of Simple Methods for the Estimation of Free Testosterone in Serum
Vermeulen, A., Verdonck, L., & Kaufman, J. M. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.10.6079 · Cited by 3,824
The physical activity scale for the elderly (PASE): Development and evaluation
Washburn, R. A., Smith, K. W., Jette, A. M., & Janney, C. A. (1993) · Journal of Clinical Epidemiology · doi:10.1016/0895-4356(93)90053-4 · Cited by 3,256
Development and evaluation of an abridged, 5-item version of the International Index of Erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction
Rosen, R., Cappelleri, J. C., Smith, M., Lipsky, J., & Peña, B. (1999) · International Journal of Impotence Research · doi:10.1038/sj.ijir.3900472 · Cited by 3,095
Longitudinal Effects of Aging on Serum Total and Free Testosterone Levels in Healthy Men
Harman, S. M., Metter, E. J., Tobin, J. D., Pearson, J., & Blackman, M. R. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.2.7219 · Cited by 2,760
Age trends in the level of serum testosterone and other hormones in middle-aged men: longitudinal results from the Massachusetts Male Aging Study
Feldman, H. A., Longcope, C., Derby, C. A., Johannes, C. B., Araujo, A. B., Coviello, A. D., Bremner, W. J., & McKinlay, J. B. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.2.8201 · Cited by 1,861
Self-citation
Utility, Limitations, and Pitfalls in Measuring Testosterone: An Endocrine Society Position Statement
Rosner, W., Auchus, R. J., Azziz, R., Sluss, P. M., & Raff, H. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-1864 · Cited by 1,176
Calculation of free and bound fractions of testosterone and estradiol-17β to human plasma proteins at body temperature
Södergard, R., Bäckström, T., Shanbhag, V., & Carstensen, H. (1982) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(82)90038-3 · Cited by 1,080

Show all 38 references

Sorted by citations

Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society Clinical Practice Guideline
Bhasin, S., Cunningham, G. R., Hayes, F. J., Matsumoto, A. M., Snyder, P. J., Swerdloff, R. S., & Montori, V. M. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-2354 · Cited by 1,954
Low Testosterone in Men with Type 2 Diabetes: Significance and Treatment
Grossmann, M. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-0118 · Cited by 350
Male hypogonadism
Basaria, S. (2014) · The Lancet · doi:10.1016/s0140-6736(13)61126-5 · Cited by 328
Lowered testosterone in male obesity: Mechanisms, morbidity and management
Grossmann, M., Tang Fui, M., & Dupuis, P. (2014) · Asian Journal of Andrology · doi:10.4103/1008-682x.122365 · Cited by 293
A Perspective on Middle-Aged and Older Men With Functional Hypogonadism: Focus on Holistic Management
Grossmann, M., & Matsumoto, A. M. (2017) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2016-3580 · Cited by 246
Endocrine Aspects of Male Sexual Dysfunctions
Buvat, J., Maggi, M., Gooren, L., Guay, A. T., Kaufman, J., Morgentaler, A., Schulman, C., Tan, H. M., Torres, L. O., Yassin, A., et al. (2010) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2010.01780.x · Cited by 221
Obesity and testicular function
Mah, P., & Wittert, G. (2009) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2009.06.007 · Cited by 183
Systematic literature review of the risk factors, comorbidities, and consequences of hypogonadism in men
Zarotsky, V., Huang, M., Carman, W. J., Morgentaler, A., Singhal, P. K., Coffin, D., & Jones, T. H. (2014) · Andrology · doi:10.1111/andr.274 · Cited by 178
Androgens and obesity
Allan, C. A., & McLachlan, R. I. (2010) · Current Opinion in Endocrinology, Diabetes & Obesity · doi:10.1097/med.0b013e3283398ee2 · Cited by 168
Hypogonadism and male obesity: Focus on unresolved questions
Grossmann, M. (2018) · Clinical Endocrinology · doi:10.1111/cen.13723 · Cited by 164
Aging and the Male Reproductive System
Kaufman, J., Lapauw, B., Mahmoud, A., T'Sjoen, G. G., & Huhtaniemi, I. T. (2019) · Endocrine Reviews · doi:10.1210/er.2018-00178 · Cited by 150
British Society for Sexual Medicine Guidelines on Adult Testosterone Deficiency, with Statements for UK Practice
Hackett, G. I., Kirby, M. G., Edwards, D., Jones, T. H., Wylie, K. R., Ossei‐Gerning, N., David, J., & Muneer, A. (2017) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2017.10.067 · Cited by 151
Outcomes of clomiphene citrate treatment in young hypogonadal men
Katz, D. J., Nabulsi, O., Tal, R., & Mulhall, J. P. (2012) · BJU International · doi:10.1111/j.1464-410x.2011.10702.x · Cited by 142
Sex hormone activity in alcohol addiction: Integrating organizational and activational effects
Lenz, B., Müller, C. P., Stoessel, C., Sperling, W., Biermann, T., Hillemacher, T., Bleich, S., & Kornhuber, J. (2011) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2011.11.001 · Cited by 145
Hormone Replacement Therapy and Physical Function in Healthy Older Men. Time to Talk Hormones?
Giannoulis, M. G., Martin, F. C., Nair, K. S., Umpleby, A. M., & Sonksen, P. (2012) · Endocrine Reviews · doi:10.1210/er.2012-1002 · Cited by 132
Diagnosis and management of testosterone deficiency syndrome in men: clinical practice guideline
Morales, Á., Bebb, R. A., Manjoo, P., Assimakopoulos, P., Axler, J., Collier, C. P., Elliott, S., Goldenberg, L., Gottesman, I. S., Grober, E. D., et al. (2015) · Canadian Medical Association Journal · doi:10.1503/cmaj.150033 · Cited by 117
Mechanisms of obesity and related pathologies: Androgen deficiency and endothelial dysfunction may be the link between obesity and erectile dysfunction
Traish, A. M., Feeley, R. J., & Guay, A. T. (2009) · FEBS Journal · doi:10.1111/j.1742-4658.2009.07305.x · Cited by 115
Predictors of sexual dysfunction incidence and remission in men
Martin, S. A., Atlantis, E., Lange, K., Taylor, A. W., O'Loughlin, P., & Wittert, G. A. (2014) · The Journal of Sexual Medicine · doi:10.1111/jsm.12483 · Cited by 105
Evidence for geographical and racial variation in serum sex steroid levels in older men
Orwoll, E. S., Nielson, C. M., Labrie, F., Barrett-Connor, E., Cauley, J. A., Cummings, S. R., Ensrud, K., Karlsson, M., Lau, E., Leung, P. C., et al. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-2435 · Cited by 100
Hypogonadism in the HIV-infected man
Rochira, V., & Guaraldi, G. (2014) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2014.06.005 · Cited by 95
Late‐onset hypogonadism: metabolic impact
Grossmann, M., Ng Tang Fui, M., & Cheung, A. S. (2020) · Andrology · doi:10.1111/andr.12705 · Cited by 95
Prevalence of low testosterone levels in men with type 2 diabetes mellitus: a cross-sectional study
Al Hayek, A., Khader, Y., Jafal, S., Khawaja, N., Robert, A., & Ajlouni, K. (2013) · Journal of Family and Community Medicine · doi:10.4103/2230-8229.122006 · Cited by 94
Diagnosis and treatment of hypogonadism in men
Bhasin, S., & Basaria, S. S. (2011) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2010.12.002 · Cited by 89
Sex Steroid Hormone Levels and Body Composition in Men
Gates, M. A., Mekary, R. A., Chiu, G. R., Ding, E. L., Wittert, G., & de Araújo, A. B. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-2582 · Cited by 85
Abdominal Obesity and Physical Inactivity Are Associated with Erectile Dysfunction Independent of Body Mass Index
Janiszewski, P. M., Janssen, I., & Ross, R. (2009) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2009.01302.x · Cited by 75
The practical management of testosterone deficiency in men
Aversa, A., & Morgentaler, A. (2015) · Nature Reviews Urology · doi:10.1038/nrurol.2015.238 · Cited by 75
MOSH Syndrome (Male Obesity Secondary Hypogonadism): Clinical Assessment and Possible Therapeutic Approaches
De Lorenzo, A., Noce, A., Moriconi, E., Rampello, T., Marrone, G., Di Daniele, N., & Rovella, V. (2018) · Nutrients · doi:10.3390/nu10040474 · Cited by 68
Male hypogonadism: pathogenesis, diagnosis, and management
de Silva, N. L., Papanikolaou, N., Grossmann, M., Antonio, L., Quinton, R., Anawalt, B. D., & Jayasena, C. N. (2024) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(24)00199-2 · Cited by 68
Predicting low testosterone in aging men: a systematic review
Millar, A. C., Lau, A. N. C., TOMLINSON, G. A., Kraguljac, A. P., Simel, D. L., Detsky, A. S., & Lipscombe, L. L. (2016) · Canadian Medical Association Journal · doi:10.1503/cmaj.150262 · Cited by 58
Clomiphene citrate for men with hypogonadism: a systematic review and meta‐analysis
Huijben, M., Lock, M. T. W. T., de Kemp, V. F., de Kort, L. M. O., & van Breda, J. (2021) · Andrology · doi:10.1111/andr.13146 · Cited by 59
Testosterone deficiency in adults and corresponding treatment patterns across the globe
Anaissie, J. E., DeLay, K. J., Wang, W., Hatzichristodoulou, G., & Hellstrom, W. J. G. (2017) · Translational Andrology and Urology · doi:10.21037/tau.2016.11.16 · Cited by 57
Do low testosterone levels contribute to ill-health during male ageing?
Yeap, B. B., de Araújo, A. B., & Wittert, G. (2012) · Critical Reviews in Clinical Laboratory Sciences · doi:10.3109/10408363.2012.725461 · Cited by 53
Metabolic Effects of Testosterone Replacement Therapy in Patients with Type 2 Diabetes Mellitus or Metabolic Syndrome: A Meta-Analysis
Li, S., Zhao, Y., Yang, Y., Wang, X., Nie, M., Wu, X., Mao, J., & Veglio, F. (2020) · International Journal of Endocrinology · doi:10.1155/2020/4732021 · Cited by 57
Adverse health effects of testosterone deficiency (TD) in men
Traish, A. M. (2014) · Steroids · doi:10.1016/j.steroids.2014.05.010 · Cited by 51
Prevalence of low testosterone and its relationship to body mass index in older men with lower urinary tract symptoms associated with benign prostatic hyperplasia
Kaplan, S. A., Lee, J. Y., O’Neill, E. A., Meehan, A. G., & Kusek, J. W. (2013) · The Aging Male · doi:10.3109/13685538.2013.844786 · Cited by 51
Función endocrina en la obesidad
Álvarez-Castro, P., Sangiao‐Alvarellos, S., Brandón-Sandá, I., & Cordido, F. (2011) · Endocrinología y Nutrición · doi:10.1016/j.endonu.2011.05.015 · Cited by 53
Partial Androgen Deficiency, Depression, and Testosterone Supplementation in Aging Men
Amore, M., Innamorati, M., Costi, S., Sher, L., Girardi, P., & Pompili, M. (2012) · International Journal of Endocrinology · doi:10.1155/2012/280724 · Cited by 46
Regulation of the Hypothalamic-Pituitary-Testicular Axis: Pathophysiology of Hypogonadism
Sharma, A., Jayasena, C. N., & Dhillo, W. S. (2022) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2021.11.010 · Cited by 50
Diagnosis and management of testosterone deficiency
Coward, R. M., McBride, J., & Carson, C. (2014) · Asian Journal of Andrology · doi:10.4103/1008-682x.143317 · Cited by 45
Late-onset hypogonadism
Dudek, P., Kozakowski, J., & Zgliczyński, W. (2017) · Menopause Review/Przegląd Menopauzalny · doi:10.5114/pm.2017.68595 · Cited by 43
Endocrine function in obesity
Álvarez-Castro, P., Sangiao‐Alvarellos, S., Brandón-Sandá, I., & Cordido, F. (2011) · Endocrinología y Nutrición (English Edition) · doi:10.1016/j.endoen.2011.05.008 · Cited by 41
Serum estradiol is associated with lean mass in elderly Swedish men
Vandenput, L., Mellström, D., Karlsson, M. K., ORWOLL, E. S., Labrie, F., Ljunggren, Ö., & Ohlsson, C. (2010) · European Journal of Endocrinology · doi:10.1530/eje-09-0696 · Cited by 38
Clinical and Biopsychosocial Determinants of Sexual Dysfunction in Middle‐Aged and Older Australian Men
Martin, S., Atlantis, E. E., Wilson, D. H., Lange, K. M., Haren, M. T., Taylor, A. W., & Wittert, G. (2012) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2012.02805.x · Cited by 38
Testosterone, physical activity, and somatic outcomes among Filipino males
Gettler, L. T., Agustin, S. S., & Kuzawa, C. W. (2010) · American Journal of Physical Anthropology · doi:10.1002/ajpa.21282 · Cited by 37
Hypogonadism in men with erectile dysfunction may be related to a host of chronic illnesses
Guay, A., Seftel, A. D., & Traish, A. M. (2009) · International Journal of Impotence Research · doi:10.1038/ijir.2009.46 · Cited by 37
The Optimal Indication for Testosterone Replacement Therapy in Late Onset Hypogonadism
Shin, Y. S., & Park, J. K. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8020209 · Cited by 34
Validation of the American Society for Reproductive Medicine guidelines/recommendations in white European men presenting for couple's infertility
Ventimiglia, E., Capogrosso, P., Boeri, L., Ippolito, S., Scano, R., Moschini, M., Gandaglia, G., Papaleo, E., Montorsi, F., & Salonia, A. (2016) · Fertility and Sterility · doi:10.1016/j.fertnstert.2016.06.044 · Cited by 32
Low testosterone levels may be associated with suicidal behavior in older men while high testosterone levels may be related to suicidal behavior in adolescents and young adults: a hypothesis
Sher, L. (2013) · International Journal of Adolescent Medicine and Health · doi:10.1515/ijamh-2013-0060 · Cited by 30
Clinical correlates of sex hormones in women: The study of health in Pomerania
Kische, H., Groß, S., Wallaschofski, H., Völzke, H., Dörr, M., Nauck, M. A., & Haring, R. (2016) · Metabolism · doi:10.1016/j.metabol.2016.05.011 · Cited by 31
Adolescent Psychiatry
Merrick, J., & Sher, L. (2013) · De Gruyter eBooks · doi:10.1515/9783110316612 · Cited by 29
Role of Metabolic Factors in the Association Between Osteocalcin and Testosterone in Chinese Men
Liao, M., Guo, X., Yu, X., Pang, G., Zhang, S., Li, J., Tan, A., Gao, Y., Yang, X., Zhang, H., et al. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-1805 · Cited by 27
Tribulus terrestris versus placebo in the treatment of erectile dysfunction and lower urinary tract symptoms in patients with late-onset hypogonadism: A placebo-controlled study
Din, S. F. G., Salam, M. A. A., Mohamed, M. S., Ahmed, A. R., Motawi, A. T., Saadeldin, O. A., & Elnabarawy, R. (2018) · Urologia Journal · doi:10.1177/0391560318802160 · Cited by 28
Sperm Concentration Is Poorly Associated With Hypoandrogenism in Infertile Men
Patel, D. P., Brant, W. O., Myers, J. B., Zhang, C., Presson, A. P., Johnstone, E. B., Dorais, J., Aston, K. I., Carrell, D. T., & Hotaling, J. M. (2015) · Urology · doi:10.1016/j.urology.2015.01.014 · Cited by 25
MANAGEMENT OF ENDOCRINE DISEASE: Rationale and current evidence for testosterone therapy in the management of obesity and its complications
Lapauw, B., & Kaufman, J. (2020) · European Journal of Endocrinology · doi:10.1530/eje-20-0394 · Cited by 24
Testosterone and depressive symptoms among men in the Diabetes Prevention Program
Kim, C., Barrett-Connor, E. L., Aroda, V. R., Mather, K. J., Christophi, C. A., Horton, E. S., Pi-Sunyer, X., Bray, G. A., Labrie, F., & Golden, S. H. (2016) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2016.06.009 · Cited by 24
Obesity, Body Composition, and Sex Hormones: Implications for Cardiovascular Risk
Singh, P., Covassin, N., Marlatt, K. L., Gadde, K. M., & Heymsfield, S. B. (2021) · Comprehensive physiology · doi:10.1002/cphy.c210014 · Cited by 44
Efficacy of Non-Testosterone-Based Treatment in Hypogonadal Men: A Review.
Raheem, O. A., Chen, T., Akula, K. P., Greenberg, J., Le, T. V., Chernobylsky, D., Sikka, S. C., & Walsh, T. J. (2021) · Sexual Medicine Reviews · doi:10.1016/j.sxmr.2020.08.003 · Cited by 22
Effects of testosterone supplement treatment in hypogonadal adult males with T2DM: a meta-analysis and systematic review
Zhang, J., Yang, B., Xiao, W., Li, X., & Li, H. (2018) · World Journal of Urology · doi:10.1007/s00345-018-2256-0 · Cited by 23
Impact of Diet-Induced Obesity and Testosterone Deficiency on the Cardiovascular System: A Novel Rodent Model Representative of Males with Testosterone-Deficient Metabolic Syndrome (TDMetS)
Donner, D. G., Elliott, G. E., Beck, B. R., Bulmer, A. C., & Toit, E. F. D. (2015) · PLoS ONE · doi:10.1371/journal.pone.0138019 · Cited by 22
Evaluating incidence, prevalence, and treatment trends in adult men with hypogonadism in the United States
Auerbach, J. M., Moghalu, O. I., Das, R., Horns, J. J., Campbell, A., Hotaling, J. M., & Pastuszak, A. W. (2021) · International Journal of Impotence Research · doi:10.1038/s41443-021-00471-2 · Cited by 21
Physiology of Penile Erection and Pathophysiology of Erectile Dysfunction
Lue, T. F. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4160-6911-9.00023-2 · Cited by 21
The Utility of Sex Hormone-Binding Globulin in Hypogonadism and Infertile Males
Ring, J. D., Welliver, C., Parenteau, M., Markwell, S. J., Brannigan, R. E., & Köhler, T. (2017) · The Journal of Urology · doi:10.1016/j.juro.2017.01.018 · Cited by 21
Clomiphene citrate: A potential alternative for testosterone therapy in hypogonadal males
Huijben, M., Lock, M. T. W. T., de Kemp, V. F., Beck, J. J. H., de Kort, L. M. O., & van Breda, J. (2023) · Endocrinology Diabetes & Metabolism · doi:10.1002/edm2.416 · Cited by 20
Cohort Profile: The Boston Area Community Health (BACH) survey
Piccolo, R., de Araújo, A. B., Pearce, N. E., & McKinlay, J. B. (2012) · International Journal of Epidemiology · doi:10.1093/ije/dys198 · Cited by 20
Self-citation
Relative contributions of multiple determinants to bone mineral density in men
Chiu, G. R., de Araújo, A. B., Travison, T. G., Hall, S. A., & McKinlay, J. B. (2009) · Osteoporosis International · doi:10.1007/s00198-009-0895-0 · Cited by 19
Self-citation
Development of a men's Preference for Testosterone Replacement Therapy (P-TRT) instrument
Szeinbach, S. L., Seoane-Vazquez, E. C., & Summers, K. H. (2012) · Patient Preference and Adherence · doi:10.2147/ppa.s35840 · Cited by 19
Testosterone therapy in older men with late-onset hypogonadism: a counter-rationale
Basaria, S. (2013) · Endocrine Practice · doi:10.4158/ep13318.ra · Cited by 18
Testosterone Supplementation Therapy in the Treatment of Patients with Metabolic Syndrome
Kovac, J. R., Pastuszak, A. W., Lamb, D. J., & Lipshultz, L. I. (2014) · Postgraduate Medicine · doi:10.3810/pgm.2014.11.2843 · Cited by 18
Validation of an Arabic ADAM questionnaire for androgen deficiency screening in the Arab community
Rabah, D. M., & Arafa, M. A. (2009) · The Aging Male · doi:10.3109/13685530903265065 · Cited by 18
JATENZO®: Challenges in the development of oral testosterone
Patel, M., Muthigi, A., & Ramasamy, R. (2021) · International Journal of Impotence Research · doi:10.1038/s41443-021-00461-4 · Cited by 17
The effect of testosterone on mood and well‐being in men with erectile dysfunction in a randomized, placebo‐controlled trial
Spitzer, M., Basaria, S. S., Travison, T. G., Davda, M. N., Derogatis, L. R., & Bhasin, S. (2013) · Andrology · doi:10.1111/j.2047-2927.2013.00075.x · Cited by 17
Self-citation
The association of cardiorespiratory fitness, body mass index, and age with testosterone levels at screening of healthy men undergoing preventive medical examinations: The Cooper Center Longitudinal Study
DeFina, L. F., Radford, N. B., Leonard, D. S., Wilson, R. K., Cooper, T. C., Clark, S. M., Willis, B. L., Vega, G. L., Barlow, C. E., Farrell, S. W., et al. (2018) · Maturitas · doi:10.1016/j.maturitas.2018.09.004 · Cited by 16
Is there an increased cardiovascular risk in patients with prolactinoma? A challenging question
Yazıcı, D., Sünbül, M., Yasar, M., Deyneli, O., & Yavuz, D. G. (2021) · Journal of Clinical Ultrasound · doi:10.1002/jcu.23030 · Cited by 16
The prevalence of Hypogonadism among diabetic and non-diabetic men in Jordan
Hayek, A. A., Khawaja, N. M., Khader, Y. S., Jafal, S., & Ajlouni, K. M. (2013) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2013.11.004 · Cited by 15
Testosterone therapy improves well being and psychological health
Akerman, J., Kovac, J. R., & Lipshultz, L. I. (2017) · Current Opinion in Urology · doi:10.1097/mou.0000000000000440 · Cited by 16
Advanced Chronic Kidney Disease is a Strong Predictor of Hypogonadism and is Associated with Decreased Lean Tissue Mass
Skiba, R., Matyjek, A., Syryło, T., Niemczyk, S., & Rymarz, A. (2020) · International Journal of Nephrology and Renovascular Disease · doi:10.2147/ijnrd.s275554 · Cited by 15
Age-related changes in serum reproductive hormone levels and prevalence of androgen deficiency in Chinese community-dwelling middle-aged and aging men
Zhou, S.-J., Zhao, M., Yang, Y., Guan, D., Li, Z.-G., Ji, Y.-D., Zhang, B., Shang, X., Xiong, C., & Gu, Y. (2020) · Medicine · doi:10.1097/md.0000000000018605 · Cited by 13
Testosterone deficiency syndrome: Diagnosis and treatment
García-Cruz, E., & Alcaraz, A. (2020) · Actas Urológicas Españolas (English Edition) · doi:10.1016/j.acuroe.2019.10.008 · Cited by 12
What are the benefits and harms of testosterone therapy for male sexual dysfunction?—a systematic review
Dimitropoulos, K., Verze, P., den Broeck, T. V., Salonia, A., Yuan, C. Y., Konstantinos Hatzimouratidis, A., & Dohle, G. R. (2019) · International Journal of Impotence Research · doi:10.1038/s41443-019-0131-1 · Cited by 11
How Does Androgen Deprivation Therapy Affect Mental Health including Cognitive Dysfunction in Patients with Prostate Cancer?
Lee, H. H., Park, S., Joung, J. Y., & Kim, S. H. (2020) · The World Journal of Men s Health · doi:10.5534/wjmh.200092 · Cited by 11
Immunity, Hormones, and Life History Trade-Offs
Muehlenbein, M. P., Prall, S. P., & Peck, H. N. (2017) · Springer eBooks · doi:10.1007/978-1-4939-4038-7_7 · Cited by 10
The clinical and epidemiological characteristics of hypogonadism in men with type 2 diabetes mellitus
Mel'nichenko, G. A., Shestakova, M. V., & Rozhivanov, R. V. (2020) · Diabetes Mellitus · doi:10.14341/dm10211 · Cited by 10
Síndrome de déficit de testosterona: diagnóstico y tratamiento
García-Cruz, E., & Alcaraz, A. (2020) · Actas Urológicas Españolas · doi:10.1016/j.acuro.2019.10.009 · Cited by 10
The Impact of Obesity on Patient Reported Outcomes Following Stereotactic Body Radiation Therapy for Prostate Cancer
Koneru, H., Cyr, R. A., Feng, L., Bae, E., Danner, M. T., Ayoob, M., Yung, T. M., Lei, S., Collins, B. T., Saligan, L. N., et al. (2016) · Cureus · doi:10.7759/cureus.669 · Cited by 10
The effect of different administrations of testosterone therapy on adverse prostate events: A Bayesian network meta-analysis
Zeng, B., Qiu, S., Xiong, X., Su, X., Zhang, Z., Wei, Q., & Yang, L. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.1009900 · Cited by 9
Sociodemographic patterns in pharmacy dispensing of medications for erectile dysfunction in Sweden
Bjerkeli, P. J., Mulinari, S., Zettermark, S., & Merlo, J. (2017) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-017-2361-9 · Cited by 9
Clomiphene citrate treatment for late onset hypogonadism: rise and fall
Marconi, M., Souper, R., Hartmann, J., Alvarez, M., Fuentes, I., & Guarda, F. J. (2016) · International braz j urol · doi:10.1590/s1677-5538.ibju.2016.0112 · Cited by 11
Hypogonadism
Sigalos, J. T., Pastuszak, A. W., & Khera, M. (2017) · Medical Clinics of North America · doi:10.1016/j.mcna.2017.10.011 · Cited by 10
Disfunção do eixo gonadotrófico em homens com infecção pelo HIV/Aids
Ponte, C. M. M., Castelo, M. H. C. G., & Montenegro, R. M. (2009) · Arquivos Brasileiros de Endocrinologia & Metabologia · doi:10.1590/s0004-27302009000800012 · Cited by 8
Impact of baseline total testosterone level on successful treatment of sexual dysfunction in men taking once-daily tadalafil 5 mg for lower urinary tract symptoms and benign prostatic hyperplasia: an integrated analysis of three randomized controlled trials
Mulhall, J. P., Brock, G. B., Glina, S., Baygani, S., Donatucci, C. F., & Maggi, M. (2016) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2016.02.163 · Cited by 7
Dysbiosis of Gut Microbiome Aggravated Male Infertility in Captivity of Plateau Pika
Zhang, L., Tang, X., Fan, C., Ren, S., Cheng, Q., Zhou, H., Liu, K., Jia, S., & Zhang, Y. (2024) · Biomolecules · doi:10.3390/biom14040403 · Cited by 7
Psychometric evaluation of the persian version of the 'aging male scales' questionnaire.
Ardebili, H. E., Khosravi, S., Larijani, B. A., Nedjat, S., & Nasrabadi, A. N. (2014) · Europe PMC (PubMed Central) · Cited by 7
Prevalence of Late-Onset Hypogonadism in Men with Localized and Metastatic Renal Cell Carcinoma
Ralla, B., Magheli, A., Wolff, I., Erber, B., Goranova, I., Friedersdorff, F., Hinz, S., Kempkensteffen, C., Miller, K., & Busch, J. F. (2016) · Urologia Internationalis · doi:10.1159/000450652 · Cited by 7
The prevalence of hypogonadism in men with type 2 diabetes mellitus in clinical practice
Mel'nichenko, G. A., Shestakova, M. V., & Rozhivanov, R. V. (2019) · Diabetes Mellitus · doi:10.14341/dm9944 · Cited by 7
Dietary patterns and testosterone balance: a review of clinical data and perspectives
Liu, X., Li, X., Cai, D., Sun, J., & Bai, W. (2025) · Journal of Advanced Research · doi:10.1016/j.jare.2025.11.016 · Cited by 6
Novel perspectives of testosterone therapy in men with functional hypogonadism: traversing the gaps of knowledge
Antonič, K. G., & Zitzmann, M. (2023) · The Aging Male · doi:10.1080/13685538.2023.2296460 · Cited by 7
Hypogonadism among Jordanian men with type 2 diabetes: Prevalence and associated factor
Hayek, A. A., Khader, Y. S., Jafal, S., Khawaja, N. M., & Ajlouni, K. M. (2011) · International Journal of Diabetes Mellitus · doi:10.1016/j.ijdm.2011.01.003 · Cited by 6
Testosterone prescribing in the population-a short social epidemiological analysis in Sweden
Bjerkeli, P. J., Mulinari, S., & Merlo, J. (2015) · Pharmacoepidemiology and Drug Safety · doi:10.1002/pds.3836 · Cited by 5
Ageing male (part 2): Management of functional hypogonadism in older men, a patient-centric holistic approach
Wu, F. C. W. (2022) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2022.101626 · Cited by 6
Are Men’s Religious Ties Hormonally Regulated?
Das, A. (2018) · Adaptive Human Behavior and Physiology · doi:10.1007/s40750-018-0094-3 · Cited by 5

Authors: Hall, S. A., Esche, G. R., Araujo, A. B., Travison, T. G., Clark, R. V., Williams, R. E., & McKinlay, J. B.
Affiliations: New England Research Institutes (US)
New England Research Institutes (S.A.H., G.R.E., A.B.A., T.G.T., J.B.M.), Watertown, Massachusetts 02474
GlaxoSmithKline (United States) (US)
Corresponding author: Hall, Susan A.
ORCID: Hall, Susan A.
Travison, Thomas G.
Clark, Richard V.
Venue: The Journal of Clinical Endocrinology & Metabolism
Publisher: The Endocrine Society
Published: 2008-10-01
Volume: 93
Issue: 10
Pages: 3870-3877
ISSN: 0021-972X (ISSN-L)
1945-7197
DOI: 10.1210/jc.2008-0021
PMC: PMC2579652
OpenAlex: W2163966418
Cited by: 167
References: 38
Citations by year: 2025: 7 · 2024: 7 · 2023: 5 · 2022: 12 · 2021: 9 · 2020: 14 · 2019: 8 · 2018: 11 · 2017: 16 · 2016: 10 · 2015: 8 · 2014: 13 · 2013: 12 · 2012: 10
FWCI: 5.81
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: GlaxoSmithKline
New England Research Institutes
National Institute on Aging (R01AG020727)
National Institute of Diabetes and Digestive and Kidney Diseases (DK56842, U01DK056842, R01DK056842)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
Health Sciences › Medicine › Reproductive Medicine › Sperm and Testicular Function
Keywords: androgen deficiency, waist circumference, risk factors, per capita income, age, health status, free testosterone, serum total testosterone, erectile dysfunction, low libido, community-dwelling men
MeSH terms: Adult, Aged, Androgens, Body Composition, Cross-Sectional Studies, Demography, Endocrine System Diseases, Female, Humans, Life Style, Male, Middle Aged, Models, Theoretical, Risk Factors, Testosterone, Comorbidity, Multivariate Analysis, Waist-Hip Ratio

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Correlates of Low Testosterone and Symptomatic Androgen Deficiency in a Population-Based Sample

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks