Cited by 475

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Genetic and Metabolic Determinants of Plasma PCSK9 Levels

Lakoski, Susan G., Lagace, Thomas A., Cohen, Jonathan C., Horton, Jay D., Hobbs, Helen H.·2009·The Journal of Clinical Endocrinology & Metabolism

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1210/jc.2009-0141

Cites

3 of 3 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 23

  1. Seidah, 2003, The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation., Proc Natl Acad Sci USA, 100, 928, 10.1073/pnas.0335507100 · DOI · Paper page
  2. Kotowski, 2006, A spectrum of PCSK9 alleles contributes to plasma levels of low-density lipoprotein cholesterol., Am J Hum Genet, 78, 410, 10.1086/500615 · DOI · Paper page
  3. Abifadel, 2003, Mutations in PCSK9 cause autosomal dominant hypercholesterolemia., Nat Genet, 34, 154, 10.1038/ng1161 · DOI · Paper page
  4. Horton, 2007, Molecular biology of PCSK9: its role in LDL metabolism., Trends Biochem Sci, 32, 71, 10.1016/j.tibs.2006.12.008 · DOI · Paper page
  5. Zaid, 2008, Proprotein convertase subtilisin/kexin type 9 (PCSK9): hepatocyte-specific low-density lipoprotein receptor degradation and critical role in mouse liver regeneration., Hepatology, 48, 646, 10.1002/hep.22354 · DOI · Paper page
  6. Lagace, 2006, Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice., J Clin Invest, 116, 2995, 10.1172/JCI29383 · DOI · Paper page
  7. Alborn, 2007, Serum proprotein convertase subtilisin kexin type 9 is correlated directly with serum LDL cholesterol., Clin Chem, 53, 1814, 10.1373/clinchem.2007.091280 · DOI
  8. Lambert, 2008, Plasma PCSK9 concentrations correlate with LDL and total cholesterol in diabetic patients and are decreased by fenofibrate treatment., Clin Chem, 54, 1038, 10.1373/clinchem.2007.099747 · DOI
  9. Mayne, 2008, Plasma PCSK9 levels are significantly modified by statins and fibrates in humans, Lipids Health Dis, 7, 22, 10.1186/1476-511X-7-22 · DOI
  10. Victor, 2004, The Dallas Heart Study: a population-based probability sample for the multidisciplinary study of ethnic differences in cardiovascular health., Am J Cardiol, 93, 1473, 10.1016/j.amjcard.2004.02.058 · DOI
  11. Frank-Kamenetsky, 2008, Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates., Proc Natl Acad Sci USA, 105, 11915, 10.1073/pnas.0805434105 · DOI
  12. Zhao, 2006, Molecular characterization of loss-of-function mutations in PCSK9 and identification of a compound heterozygote., Am J Hum Genet, 79, 514, 10.1086/507488 · DOI
  13. Chang, 2007, Associations among androgens, estrogens, and natriuretic peptides in young women: observations from the Dallas Heart Study., J Am Coll Cardiol, 49, 109, 10.1016/j.jacc.2006.10.040 · DOI
  14. Careskey, 2008, Atorvastatin increases human serum levels of proprotein convertase subtilisin/kexin type 9., J Lipid Res, 49, 394, 10.1194/jlr.M700437-JLR200 · DOI
  15. Boerwinkle, 1988, Simultaneous effects of the apolipoprotein E polymorphism on apolipoprotein E, apolipoprotein B, and cholesterol metabolism., Am J Hum Genet, 42, 104
  16. Dubuc, 2004, Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia., Arterioscler Thromb Vasc Biol, 24, 1454, 10.1161/01.ATV.0000134621.14315.43 · DOI · Paper page
  17. Rashid, 2005, Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9., Proc Natl Acad Sci USA, 102, 5374, 10.1073/pnas.0501652102 · DOI · Paper page
  18. Mayne, 2007, Plasma PCSK9 levels correlate with cholesterol in men but not in women., Biochem Biophys Res Commun, 361, 451, 10.1016/j.bbrc.2007.07.029 · DOI · Paper page
  19. Horton, 2003, Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes., Proc Natl Acad Sci USA, 100, 12027, 10.1073/pnas.1534923100 · DOI · Paper page
  20. Grefhorst, 2008, Plasma PCSK9 preferentially reduces liver LDL receptors in mice., J Lipid Res, 49, 1303, 10.1194/jlr.M800027-JLR200 · DOI · Paper page
  21. Luo, 6 2008, Function and distribution of circulating human PCSK9 expressed extrahepatically in transgenic mice., J Lipid Res, in press
  22. Costet, 2006, Hepatic PCSK9 expression is regulated by nutritional status via insulin and sterol regulatory element-binding protein 1c., J Biol Chem, 281, 6211, 10.1074/jbc.M508582200 · DOI
  23. Browning, 2004, Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity., Hepatology, 40, 1387, 10.1002/hep.20466 · DOI · Paper page

Cited by

Sorted by citations

Metadata

Authors
Lakoski, S. G., Lagace, T. A., Cohen, J. C., Horton, J. D., & Hobbs, H. H.
Affiliations
  • Donald W. Reynolds Cardiovascular Clinical Research Center, Departments of Internal Medicine (S.G.L., J.C.C., J.D.H., H.H.H.), University of Texas Southwestern Medical Center, Dallas, Texas 75390-9046
  • Molecular Genetics (T.A.L., J.D.H., H.H.H.), University of Texas Southwestern Medical Center, Dallas, Texas 75390-9046
Venue
The Journal of Clinical Endocrinology & Metabolism
Published
2009-07-01
Volume
94
Issue
7
Pages
2537-2543
ISSN
  • 0021-972X
  • 1945-7197
Cited by
475
References
3
Language
en

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review