Pituitary Size in Depression*
Abstract
Magnetic resonance images centered at the pituitary stalk were used to measure pituitary gland size in 19 patients with major depression compared with that in age- and sex-matched controls. Depressed patients had significantly greater pituitary cross-sectional area (P = 0.0009) and volume (P = 0.007) than the controls. This difference was particularly prominent in elderly depressed patients compared to elderly controls. These results provide the first demonstration of structural alterations in the pituitary gland in major depression.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
MRI-based measures of cross-sectional area and volume of the pituitary were increased (by 34 and 41%, respectively) in depressives versus controls.
“For example Krishnan et al. (1991) showed that MRI-based measures of cross-sectional area and volume of the pituitary were increased (by 34 and 41%, respectively) in depressives versus controls.”
From Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression (2008) · cites this paper as Krishnan et al. (1991)
Cites
Carroll, B. J. (1981) · Archives of General Psychiatry · doi:10.1001/archpsyc.1981.01780260017001 · Cited by 2,243 · see citing works
Nemeroff, C. B., Widerlöv, E., Bissette, G., Walléus, H., Karlsson, I., Eklund, K., Kilts, C. D., Loosen, P. T., & Vale, W. (1984) · Science · doi:10.1126/science.6334362 · Cited by 1,485 · see citing works
Self-citationPsychiatric implications of basic and clinical studies with corticotropin-releasing factor.
Gold, P., Chrousos, G., Kellner, C., Post, R., Roy, A., Augerinos, P., Schulte, H., Oldfield, E., & Loriaux, D. (1984) · American Journal of Psychiatry · doi:10.1176/ajp.141.5.619 · Cited by 460 · see citing works
Development and aging of brain midline structures: assessment with MR imaging.
Hayakawa, K., Konishi, Y., MATSUDA, T., Kuriyama, M., Konishi, K., Yamashita, K., Okumura, R., & Hamanaka, D. (1989) · Radiology · doi:10.1148/radiology.172.1.2740500 · Cited by 168 · see citing works
Westlund, K. N., Aguilera, G., & Childs, G. V. (1985) · Endocrinology · doi:10.1210/endo-116-1-439 · Cited by 99 · see citing works
Blunting of ACTH response to human CRH in depressed patients is avoided by metyrapone pretreatment
von Bardeleben, U., Stalla, G. K., Müller, O. A., & Holsboer, F. (1988) · Biological Psychiatry · doi:10.1016/0006-3223(88)90254-5 · Cited by 81 · see citing works
Lisansky, J. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810070067011 · Cited by 72 · see citing works
Doraiswamy, P. M., Krishnan, K. R. R., Figiel, G. S., Husain, M. M., Boyko, O. B., Rockwell, W. J. K., & Ellinwood, E. H. (1990) · Biological Psychiatry · doi:10.1016/0006-3223(90)90628-f · Cited by 68 · see citing works
Self-citationMagnetic Resonance Imaging of Pituitary and Parasellar Abnormalities
Chakeres, D. W., Curtin, A., & Ford, G. (1989) · Radiologic Clinics of North America · doi:10.1016/s0033-8389(22)00875-2 · Cited by 65 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Drevets, W. C., Price, J. L., & Furey, M. L. (2008) · Brain Structure and Function · doi:10.1007/s00429-008-0189-x · Cited by 2,209 · see citing works
“For example Krishnan et al. (1991) showed that MRI-based measures of cross-sectional area and volume of the pituitary were increased (by 34 and 41%, respectively) in depressives versus controls.”
BackgroundResultNeurocircuitry of Mood Disorders
Price, J. L., & Drevets, W. C. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.104 · Cited by 1,606 · see citing works
The role of corticotropin-releasing factor in depression and anxiety disorders
Arborelius, L., Owens, M., Plotsky, P., & Nemeroff, C. (1999) · Journal of Endocrinology · doi:10.1677/joe.0.1600001 · Cited by 1,378 · see citing works
Self-citationNeuroimaging studies of mood disorders
Drevets, W. C. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(00)01020-9 · Cited by 1,313 · see citing works
The stress system in the human brain in depression and neurodegeneration
Swaab, D. F., Bao, A.-M., & Lucassen, P. J. (2005) · Ageing Research Reviews · doi:10.1016/j.arr.2005.03.003 · Cited by 984 · see citing works
The anatomy of mood disorders—review of structural neuroimaging studies
Soares, J. C., & Mann, J. J. (1997) · Biological Psychiatry · doi:10.1016/s0006-3223(96)00006-6 · Cited by 760 · see citing works
PSYCHONEUROENDOCRINOLOGY OF DEPRESSION
Plotsky, P. M., Owens, M. J., & Nemeroff, C. B. (1998) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(05)70006-x · Cited by 672 · see citing works
Self-citationThe stress system in depression and neurodegeneration: Focus on the human hypothalamus
Bao, A., Meynen, G., & Swaab, D. F. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.04.005 · Cited by 547 · see citing works
Depression in Patients With Cancer
McDaniel, J. S. (1995) · Archives of General Psychiatry · doi:10.1001/archpsyc.1995.03950140007002 · Cited by 541 · see citing works
Heim, C., & Nemeroff, C. B. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00224-3 · Cited by 502 · see citing works
Self-citationArnone, D., McIntosh, A. M., Ebmeier, K. P., Munafò, M. R., & Anderson, I. M. (2012) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2011.05.003 · Cited by 495 · see citing works
Chronic pain, chronic stress and depression: Coincidence or consequence?
Blackburn‐Munro, G., & Blackburn‐Munro, R. E. (2001) · Journal of Neuroendocrinology · doi:10.1046/j.0007-1331.2001.00727.x · Cited by 493 · see citing works
Drevets, W. C., Price, J. L., Bardgett, M. E., Reich, T., Todd, R. D., & Raichle, M. E. (2002) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(01)00687-6 · Cited by 457 · see citing works
Steffens, D. C., & Krishnan, K. (1998) · Biological Psychiatry · doi:10.1016/s0006-3223(98)00084-5 · Cited by 392 · see citing works
Self-citationvan Praag, H. M. (2004) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2004.05.031 · Cited by 378 · see citing works
The neuroendocrinology of depression and chronic stress
Checkley, S. (1996) · British Medical Bulletin · doi:10.1093/oxfordjournals.bmb.a011570 · Cited by 323 · see citing works
Pathophysiology of hypercortisolism in depression
Carroll, B. J., Cassidy, F., Naftolowitz, D., Tatham, N. E., Wilson, W. H., Iranmanesh, A., Liu, P. Y., & Veldhuis, J. D. (2007) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2007.00967.x · Cited by 317 · see citing works
Pituitary volumes in pediatric maltreatment-related posttraumatic stress disorder
Thomas, L. A., & Bellis, M. D. D. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2003.11.021 · Cited by 267 · see citing works
The Hypothalamic-Pituitary-Adrenal Axis in Major Depressive Disorder
Varghese, F. P., & Brown, E. S. (2001) · The Primary Care Companion For CNS Disorders · doi:10.4088/pcc.v03n0401 · Cited by 236 · see citing works
Volumetric brain imaging findings in mood disorders
Beyer, J. L., & Krishnan, K. (2002) · Bipolar Disorders · doi:10.1034/j.1399-5618.2002.01157.x · Cited by 231 · see citing works
Self-citationMRI findings in patients with affective disorder: a meta‐analysis
Videbech, P. (1997) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1997.tb10146.x · Cited by 226 · see citing works
The effects of neonatal stress on brain development: implications for psychopathology
GRAHAM, Y. P., HEIM, C., GOODMAN, S. H., MILLER, A. H., & NEMEROFF, C. B. (1999) · Development and Psychopathology · doi:10.1017/s0954579499002205 · Cited by 197 · see citing works
Self-citationStokes, P. E. (1995) · European Neuropsychopharmacology · doi:10.1016/0924-977x(95)00039-r · Cited by 188 · see citing works
Invited review: the evolution of antidepressant mechanisms
Slattery, D. A., Hudson, A. L., & Nutt, D. (2004) · Fundamental and Clinical Pharmacology · doi:10.1111/j.1472-8206.2004.00195.x · Cited by 185 · see citing works
van Praag, H. M. (2005) · The World Journal of Biological Psychiatry · doi:10.1080/15622970510030018 · Cited by 184 · see citing works
Risk Factors for Development of Depression and Psychosis
Pariante, C. M. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.04978.x · Cited by 181 · see citing works
Owens, M. J., & Nemeroff, C. B. (2007) · Novartis Foundation symposium · doi:10.1002/9780470514368.ch15 · Cited by 181 · see citing works
Self-citationPariante, C. M., Vassilopoulou, K., Velakoulis, D., Phillips, L., Soulsby, B., Wood, S. J., Brewer, W., Smith, D., Dazzan, P., Yung, A. R., et al. (2004) · British Journal of Psychiatry · doi:10.1192/bjp.185.1.5 · Cited by 180 · see citing works
Elevated neuron number in the limbic thalamus in major depression
Young, K. A., Holcomb, L. A., Yazdani, U., Hicks, P. B., & German, D. C. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.7.1270 · Cited by 169 · see citing works
Mood and neuropsychological function in depression: the role of corticosteroids and serotonin
McAllister-Williams, H., Ferrier, I. N., & Young, A. H. (1998) · Psychological Medicine · doi:10.1017/s0033291798006680 · Cited by 165 · see citing works
Assessment and treatment of depression in the cancer patient
Newport, D. J., & Nemeroff, C. B. (1998) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(98)00011-7 · Cited by 167 · see citing works
Self-citationPompili, M., Serafini, G., Innamorati, M., Möller-Leimkühler, A. M., Giupponi, G., Girardi, P., Tatarelli, R., & Lester, D. (2010) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-010-0108-z · Cited by 160 · see citing works
Holsboer, F., Spengler, D., & Heuser, I. (1992) · Progress in brain research · doi:10.1016/s0079-6123(08)64586-0 · Cited by 158 · see citing works
Depression and Endocrine Disorders: Focus on the Thyroid and Adrenal System
Musselman, D. L., & Nemeroff, C. B. (1996) · The British Journal of Psychiatry · doi:10.1192/s0007125000298504 · Cited by 156 · see citing works
Self-citationPariante, C. M., Dazzan, P., Danese, A., Morgan, K. D., Brudaglio, F., Morgan, C., Fearon, P., Orr, K., Hutchinson, G., Pantelis, C., et al. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300766 · Cited by 152 · see citing works
Axelson, D., Doraiswamy, P. M., Boyko, O. B., Escalona, P. R., McDonald, W. M., Ritchie, J., Patterson, L. J., Ellinwood, E. H., Nemeroff, C. B., & Krishnan, K. (1992) · Psychiatry Research · doi:10.1016/0165-1781(92)90070-j · Cited by 147 · see citing works
Self-citationAtypical Antipsychotics and Pituitary Tumors: A Pharmacovigilance Study
Szarfman, A., Tonning, J. M., Levine, J. G., & Doraiswamy, P. M. (2006) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1592/phco.26.6.748 · Cited by 143 · see citing works
Self-citationThe neuropsychology of mood disorders
Chamberlain, S. R., & Sahakian, B. J. (2006) · Current Psychiatry Reports · doi:10.1007/s11920-006-0051-x · Cited by 140 · see citing works
Decreased pituitary volume in patients with bipolar disorder
Sassi, R. B., Nicoletti, M., Brambilla, P., Harenski, K. A., Mallinger, A. G., Frank, E., Kupfer, D. J., Keshavan, M. S., & Soares, J. C. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01086-1 · Cited by 137 · see citing works
Brain Systems Underlying Susceptibility to Helplessness and Depression
Shumake, J., & Gonzalez-Lima, F. (2003) · Behavioral and Cognitive Neuroscience Reviews · doi:10.1177/1534582303259057 · Cited by 135 · see citing works
Brain-immune interactions and disease susceptibility
Marques-Deak, A., Cizza, G., & Sternberg, E. M. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001643 · Cited by 132 · see citing works
Brain Structural Effects of Antidepressant Treatment in Major Depression
Dusi, N., Barlati, S., Vita, A., & Brambilla, P. (2015) · Current Neuropharmacology · doi:10.2174/1570159x1304150831121909 · Cited by 129 · see citing works
The role of Corticotropin Releasing Factor in Depressive Illness: a Critical Review
Mitchell, A. J. (1998) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(97)00059-6 · Cited by 115 · see citing works
Endocrine disturbances in depression
Tichomirowa, M. A., Keck, M. E., Schneider, H. J., Páez-Pereda, M., Renner, U., Holsboer, F., & Stalla, G. K. (2005) · Journal of Endocrinological Investigation · doi:10.1007/bf03345535 · Cited by 111 · see citing works
Anatomical MRI findings in mood and anxiety disorders
Brambilla, P., Barale, F., Caverzasi, E., & Soares, J. C. (2002) · Epidemiologia e Psichiatria Sociale · doi:10.1017/s1121189x00005558 · Cited by 104 · see citing works
Normal development of the pituitary gland: assessment with three-dimensional MR volumetry.
Takano, K., Utsunomiya, H., Ono, H., Ohfu, M., & Okazaki, M. (1999) · PubMed Central · Cited by 103 · see citing works
The Neuroendocrinology of Mood Disorders
Rubín, R. T., & Carroll, B. J. (2009) · Elsevier eBooks · doi:10.1016/b978-008088783-8.00092-9 · Cited by 103 · see citing works
HPA Axis Interactions with Behavioral Systems
Packard, A. E. B., Egan, A. E., & Ulrich‐Lai, Y. M. (2016) · Comprehensive physiology · doi:10.1002/cphy.c150042 · Cited by 130 · see citing works
Doraiswamy, P. M., Potts, J., Axelson, D., Husain, M. M., Lurie, S. N., Na, C., Escalona, P. R., McDonald, W. M., Figiel, G. S., & Ellinwood, E. H. (1992) · PubMed Central · Cited by 99 · see citing works
Self-citationLorenzetti, V., Solowij, N., Fornito, A., Lubman, D. I., & Yücel, M. (2014) · Current Pharmaceutical Design · doi:10.2174/13816128113199990435 · Cited by 96 · see citing works
Wolf, O. T., Convit, A. J., de Leon, M. J., Caraos, C., & Qadri, S. F. (2002) · Neuroendocrinology · doi:10.1159/000054715 · Cited by 95 · see citing works
Changes in the immune system in depression and dementia: causal or co‐incidental effects?
Leonard, B. E. (2001) · International Journal of Developmental Neuroscience · doi:10.1016/s0736-5748(01)00014-4 · Cited by 91 · see citing works
Corticotropin-releasing hormone and the hypothalamic–pituitary–adrenal axis in psychiatric disease
Naughton, M., Dinan, T. G., & Scott, L. V. (2014) · Handbook of clinical neurology · doi:10.1016/b978-0-444-59602-4.00005-8 · Cited by 90 · see citing works
Adrenal Size Is Increased in Multiple Sclerosis
Reder, A. T., Makowiec, R. L., & Lowy, M. T. (1994) · Archives of Neurology · doi:10.1001/archneur.1994.00540140057015 · Cited by 89 · see citing works
Structural Changes in the Brain in Depression and Relationship to Symptom Recurrence
Bremner, J. D. (2002) · CNS Spectrums · doi:10.1017/s1092852900017442 · Cited by 86 · see citing works
MRI study of the pituitary gland in adolescent depression
MacMaster, F. P., & Kusumakar, V. (2004) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2003.11.001 · Cited by 85 · see citing works
Interaction of prefrontal cortical and hypothalamic systems in the pathogenesis of depression
Swaab, D. F., Fliers, E., Hoogendijk, W. J. G., Veltman, D. J., & Zhou, J. (2000) · Progress in brain research · doi:10.1016/s0079-6123(00)26025-1 · Cited by 81 · see citing works
Molitch, M. E. (1997) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(05)70279-6 · Cited by 81 · see citing works
Vasopressin as a target for antidepressant development: an assessment of the available evidence
Scott, L. V., & Dinan, T. G. (2002) · Journal of Affective Disorders · doi:10.1016/s0165-0327(02)00026-5 · Cited by 79 · see citing works
Jovev, M., Garner, B., Phillips, L., Velakoulis, D., Wood, S. J., Jackson, H. J., Pantelis, C., McGorry, P. D., & Chanen, A. M. (2008) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2007.12.003 · Cited by 76 · see citing works
Pituitary volume in psychosis: the first review of the evidence
Pariante, C. M. (2008) · Journal of Psychopharmacology · doi:10.1177/0269881107084020 · Cited by 73 · see citing works
Neuroplasticity in mood disorders
Drevets, W. C. (2004) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2004.6.2/wdrevets · Cited by 73 · see citing works
Pituitary volume in unaffected relatives of patients with schizophrenia and bipolar disorder
Mondelli, V., Dazzan, P., Gabilondo, A., Tournikioti, K., Walshe, M., Marshall, N., Schulze, K. K., Murray, R. M., McDonald, C., & Pariante, C. M. (2008) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2008.05.010 · Cited by 72 · see citing works
O'Brien, J. T., Ames, D. J., Schweitzer, I., Mastwyk, M., & Colman, P. G. (1996) · Psychological Medicine · doi:10.1017/s0033291700033675 · Cited by 70 · see citing works
Hypothesis: Cytokines may be activated to cause depressive illness and chronic fatigue syndrome
Ur, E., White, P. D., & Grossman, A. B. (1992) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/bf02195983 · Cited by 68 · see citing works
Torpy, D. J., & Chrousos, G. P. (1996) · Baillière s Clinical Rheumatology · doi:10.1016/s0950-3579(96)80014-8 · Cited by 67 · see citing works
Pituitary gland volume in adolescent and young adult bipolar and unipolar depression
MacMaster, F. P., Leslie, R. A., Rosenberg, D. R., & Kusumakar, V. (2008) · Bipolar Disorders · doi:10.1111/j.1399-5618.2008.00476.x · Cited by 65 · see citing works
Volume of the adrenal and pituitary glands in depression
Kessing, L. V., Willer, I. S., & Knorr, U. B. (2010) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2010.05.007 · Cited by 63 · see citing works
Development and sexual dimorphism of the pituitary gland
MacMaster, F. P., Keshavan, M., Mirza, Y., Carrey, N., Upadhyaya, A. R., El-Sheikh, R., Buhagiar, C. J., Taormina, S. P., Boyd, C., Lynch, M., et al. (2007) · Life Sciences · doi:10.1016/j.lfs.2006.11.040 · Cited by 63 · see citing works
Noonan, K., Carey, L. M., & Crewther, S. G. (2012) · Journal of Stroke and Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2012.09.008 · Cited by 62 · see citing works
Workshop report: the effects of psychological variables on the progression of HIV-1 disease
Kopnisky, K. L., Stoff, D. M., & Rausch, D. M. (2003) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2003.08.003 · Cited by 62 · see citing works
Pituitary Volume in Treatment-Naïve Pediatric Major Depressive Disorder
MacMaster, F. P., Russell, A., Mirza, Y., Keshavan, M. S., Taormina, S. P., Bhandari, R., Boyd, C., Lynch, M., Rose, M., Ivey, J., et al. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.04.013 · Cited by 61 · see citing works
Kaess, M., Whittle, S., O’Brien-Simpson, L., Allen, N. B., & Simmons, J. G. (2018) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2018.08.004 · Cited by 57 · see citing works
A role for life events in the pathogenesis of Cushing's disease
Sonino, N., Fava, G. A., & Boscaro, M. (1993) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1993.tb01004.x · Cited by 58 · see citing works
Wong, A. P., Pipitone, J., Park, M. T. M., Dickie, E. W., Leonard, G. T., Perron, M., Pike, G. B., Richer, L., Veillette, S., Chakravarty, M. M., et al. (2014) · NeuroImage · doi:10.1016/j.neuroimage.2014.02.030 · Cited by 58 · see citing works
Bambico, F. R., & Belzung, C. (2012) · Current topics in behavioral neurosciences · doi:10.1007/7854_2012_234 · Cited by 57 · see citing works
Cognition in mania and depression: Psychological models and clinical implications
Chamberlain, S. R., & Sahakian, B. J. (2004) · Current Psychiatry Reports · doi:10.1007/s11920-004-0010-3 · Cited by 59 · see citing works
Pituitary Volume in Pediatric Obsessive-Compulsive Disorder
MacMaster, F. P., Russell, A., Mirza, Y., Keshavan, M. S., Banerjee, S. P., Bhandari, R. P., Boyd, C. C., Lynch, M. A., Rose, M., Ivey, J., et al. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.06.028 · Cited by 55 · see citing works
Hyperprolactinemia: Evaluation and Management
Blackwell, R. E. (1992) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(18)30234-2 · Cited by 55 · see citing works
Carroll, B. J., Iranmanesh, A., Keenan, D. M., Cassidy, F., Wilson, W. H., & Veldhuis, J. D. (2011) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2011.01821.x · Cited by 54 · see citing works
Fujita, M., Charney, D. S., & Innis, R. B. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(00)00960-4 · Cited by 53 · see citing works
Changes in the immune system in depression and dementia: causal or coincidental effects?
Leonard, B. E., & Myint, A.-M. (2006) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2006.8.2/bleonard · Cited by 51 · see citing works
Pituitary volume in neuroleptic-naïve schizophrenia: A structural MRI study
UPADHYAYA, A., ELSHEIKH, R., MACMASTER, F., DIWADKAR, V, & KESHAVAN, M. (2007) · Schizophrenia Research · doi:10.1016/j.schres.2006.09.033 · Cited by 51 · see citing works
Ertekın, T., Acer, N., Turgut, A. T., Aycan, K., Özçelik, Ö., & Turgut, M. (2010) · Pituitary · doi:10.1007/s11102-010-0254-3 · Cited by 50 · see citing works
Whittle, S., Yücel, M., Lorenzetti, V., Byrne, M. L., Simmons, J. G., Wood, S. J., Pantelis, C., & Allen, N. B. (2011) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2011.10.004 · Cited by 50 · see citing works
Structural studies of the hypothalamus and its nuclei in mood disorders
Schindler, S., Geyer, S., Strauß, M., Anwander, A., Hegerl, U., Turner, R., & Schönknecht, P. (2012) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2011.06.005 · Cited by 49 · see citing works
Roy, A., & Campbell, M. K. (2013) · Clinical and investigative medicine · doi:10.25011/cim.v36i4.19951 · Cited by 50 · see citing works
Clow, A. (2002) · International review of neurobiology · doi:10.1016/s0074-7742(02)52012-2 · Cited by 48 · see citing works
Pituitary volume in patients with bipolar disorder and their first-degree relatives
Takahashi, T., Walterfang, M., Wood, S. J., Kempton, M. J., Jogia, J., Lorenzetti, V., Soulsby, B., Suzuki, M., Velakoulis, D., Pantelis, C., et al. (2009) · Journal of Affective Disorders · doi:10.1016/j.jad.2009.12.002 · Cited by 45 · see citing works
Abnormalities of the HPA axis in affective disorders: clinical subtypes and potential treatments
Porter, R., & Gallagher, P. (2006) · Acta Neuropsychiatrica · doi:10.1111/j.1601-5215.2006.00152.x · Cited by 45 · see citing works
Bushe, C., Yeomans, D., Floyd, T., & Smith, S. M. (2008) · Journal of Psychopharmacology · doi:10.1177/0269881107088436 · Cited by 45 · see citing works
Postmortem and Cerebrospinal Fluid Studies of Corticotropin‐releasing Factor in Humansa
HARTLINE, K. M., Owens, M. J., & Nemeroff, C. B. (1996) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1996.tb15114.x · Cited by 44 · see citing works
Self-citationAntistress properties of antidepressant drugs and their clinical implications
Calabrese, F., Molteni, R., & Riva, M. A. (2011) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2011.05.007 · Cited by 41 · see citing works
Affective Disorders and Endocrine Disease
Fava, G. A. (1994) · Psychosomatics · doi:10.1016/s0033-3182(94)71755-2 · Cited by 42 · see citing works
Chen, H. H., Nicoletti, M., Sanches, M., Hatch, J. P., Sassi, R. B., Axelson, D., Brambilla, P., Keshavan, M. S., Ryan, N. D., Birmaher, B. B., et al. (2004) · Depression and Anxiety · doi:10.1002/da.20044 · Cited by 39 · see citing works
Takahashi, T., Zhou, S.-Y., Nakamura, K., Tanino, R., Furuichi, A., Kido, M., Kawasaki, Y., Noguchi, K., Seto, H., Kurachi, M., et al. (2010) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.10.023 · Cited by 38 · see citing works
Increased pituitary volume in schizophrenia spectrum disorders
Takahashi, T., Suzuki, M., Velakoulis, D., Lorenzetti, V., Soulsby, B., Zhou, S.-Y., Nakamura, K., Seto, H., Kurachi, M., & Pantelis, C. (2009) · Schizophrenia Research · doi:10.1016/j.schres.2008.12.016 · Cited by 37 · see citing works
Corticotropin-releasing factor-binding protein, stress and major depression
Eede, F. V. D., Broeckhoven, C. V., & Claes, S. J. (2005) · Ageing Research Reviews · doi:10.1016/j.arr.2005.02.002 · Cited by 37 · see citing works
Smaller pituitary volume in adult patients with obsessive–compulsive disorder
Atmaca, M., Yıldırım, H., Özler, S., Koç, M., Kara, B., & Seç, S. (2009) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2009.01981.x · Cited by 37 · see citing works
Pituitary gland volume in currently depressed and remitted depressed patients
Lorenzetti, V., Allen, N. B., Fornito, A., Pantelis, C., De Plato, G., Ang, A., & Yücel, M. (2009) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2008.06.006 · Cited by 37 · see citing works
- Authors
- KRISHNAN, K. R. R., DORAISWAMY, P. M., LURIE, S. N., FIGIEL, G. S., HUSAIN, M. M., BOYKO, O. B., ELLINWOOD, E. H., & NEMEROFF, C. B.
- Affiliations
- Duke University (US)
- ORCID
- Venue
- The Journal of Clinical Endocrinology & Metabolism
- Publisher
- The Endocrine Society
- Published
- 1991-02
- Volume
- 72
- Issue
- 2
- Pages
- 256-259
- ISSN
- 0021-972X (ISSN-L)
- 1945-7197
- OpenAlex
- W2051225255
- Cited by
- 232
- References
- 9
- Citations by year
- 2026: 1 · 2024: 1 · 2023: 3 · 2022: 2 · 2020: 2 · 2019: 1 · 2018: 1 · 2017: 3 · 2016: 5 · 2015: 7 · 2014: 7 · 2013: 4 · 2012: 6
- FWCI
- 4.74
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01mh044716-06)
- National Institute of Mental Health (R01MH042088, MH-44716, MH 40159, MH42088)
- Topics
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Pituitary Gland Disorders and Treatments
- Keywords
- major depressive disorder, pituitary volume, pituitary stalk, brain structural changes, geriatric depression, neuroimaging of depression
- MeSH terms
- Adult, Aged, Aged, 80 and over, Aging, Depressive Disorder, Female, Humans, Magnetic Resonance Imaging, Middle Aged, Pituitary Gland
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
