The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Improvement in Mood and Fatigue after Dehydroepiandrosterone Replacement in Addison’s Disease in a Randomized, Double Blind Trial
Abstract
Dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS) are adrenal precursors of steroid biosynthesis and centrally acting neurosteroids. Glucocorticoid and mineralocorticoid deficiencies in Addison's disease require life-long hormone replacement, but the associated failure of DHEA synthesis is not corrected. We conducted a randomized, double blind study in which 39 patients with Addison's disease received either 50 mg oral DHEA daily for 12 weeks, followed by a 4-week washout period, then 12 weeks of placebo, or vice versa. After DHEA treatment, levels of DHEAS and Delta(4)-androstenedione rose from subnormal to within the adult physiological range. Total testosterone increased from subnormal to low normal with a fall in serum sex hormone-binding globulin in females, but with no change in either parameter in males. In both sexes, psychological assessment showed significant enhancement of self-esteem with a tendency for improved overall well-being. Mood and fatigue also improved significantly, with benefit being evident in the evenings. No effects on cognitive or sexual function, body composition, lipids, or bone mineral density were observed. Our results indicate that DHEA replacement corrects this steroid deficiency effectively and improves some aspects of psychological function. Beneficial effects in males, independent of circulating testosterone levels, suggest that it may act directly on the central nervous system rather than by augmenting peripheral androgen biosynthesi…
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“In addition, some (but not all) studies have shown that DHEA replacement in adrenal insufficiency may improve HRQoL and mood, with reduced depression and anxiety scores (114 -116).”
From Diagnosis and Treatment of Primary Adrenal Insufficiency: An Endocrine Society Clinical Practice Guideline (2016) · cites this paper as [115]
In the citing paper
“Our previous placebo-controlled 3-month crossover trial of 39 patients (including 15 males) with primary adrenal insufficiency showed similar biochemical changes and enhanced psychological well-being, independent of gender (20).”
From Long-Term DHEA Replacement in Primary Adrenal Insufficiency: A Randomized, Controlled Trial (2008) · cites this paper as [20]
In the citing paper
“score significantly worse than age-and sexmatched population controls on validated psychological tests that measure well-being (20,21).”
From Long-Term DHEA Replacement in Primary Adrenal Insufficiency: A Randomized, Controlled Trial (2008) · cites this paper as [20]
In the citing paper
“No changes in body composition, BMD or cognition were demonstrated in any of these short-term studies of DHEA replacement.”
From Long-Term DHEA Replacement in Primary Adrenal Insufficiency: A Randomized, Controlled Trial (2008) · cites this paper as [20]
In the citing paper
“This 12-month study of DHEA replacement in patients with Addison's disease both supports the improved well-being documented in our previous short-term study and adds new information on longer-term effects of DHEA.”
From Long-Term DHEA Replacement in Primary Adrenal Insufficiency: A Randomized, Controlled Trial (2008) · cites this paper as [20]
In the citing paper
“The hormone profile of DHEA-treated subjects was similar to that observed in our previous study (20) with significant increases in androstenedione in both sexes and testosterone in women but not in men.”
From Long-Term DHEA Replacement in Primary Adrenal Insufficiency: A Randomized, Controlled Trial (2008) · cites this paper as [20]
In the citing paper
“Twenty-three subjects had taken part in our previous, short-term trial of DHEA (20) but were distributed comparably across DHEA (n ϭ 9) and placebo (n ϭ 14) groups.”
From Long-Term DHEA Replacement in Primary Adrenal Insufficiency: A Randomized, Controlled Trial (2008) · cites this paper as [20]
In the citing paper
“which is in keeping with observations in some short- (20,48,54) and longer-term trials (25) but differs from observations in women with primary or secondary adrenal failure (23,24).”
From Long-Term DHEA Replacement in Primary Adrenal Insufficiency: A Randomized, Controlled Trial (2008) · cites this paper as [20]
In the citing paper
“Despite earlier reports suggesting changes in IGF-I with DHEA replacement, both our earlier short-term trial (20) and the present study showed no statistically significant change in circulating IGF-I levels, in agreement with another recent replacement study (50), arguing against a primary role of this hormone in mediating increases in lean muscle mass.”
From Long-Term DHEA Replacement in Primary Adrenal Insufficiency: A Randomized, Controlled Trial (2008) · cites this paper as [20]
In the citing paper
“Interestingly, similar abnormalities in the self-esteem subscale of GHQ-30 occurred in both of our studies [this one and an earlier shorter-term replacement study (20)]”
From Long-Term DHEA Replacement in Primary Adrenal Insufficiency: A Randomized, Controlled Trial (2008) · cites this paper as [20]
In the citing paper
“suggesting there may be a disorderspecific profile of psychological deficit in Addison's disease.”
From Long-Term DHEA Replacement in Primary Adrenal Insufficiency: A Randomized, Controlled Trial (2008) · cites this paper as [20]
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Items 201–300 of 339
The role for long-term use of dehydroepiandrosterone in adrenal insufficiency
Bennett, G., Cussen, L., & O’Reilly, M. (2022) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0000000000000728 · Cited by 8
“, 2000 [32]) 50 mg/day for 3 months 39 patients with Addison’s disease (15 men and 24 women) In both men and women DHEA and DHEAS " to normal levels.”
BackgroundAndrogen Replacement Therapy in Androgen-Deficient Women with Hypopituitarism
Zang, H., & Davis, S. R. (2008) · Drugs · doi:10.2165/00003495-200868150-00001 · Cited by 7
“[65,66] In a randomized, placebo-controlled, leagues[61] used DHEA 50 mg/day or placebo for double-blind study, Johannsson et al.”
BackgroundMethodFemale Sexual Dysfunction in Primary Adrenal Insufficiency
Zamponi, V., Lardo, P., Maggio, R., Simonini, C., Mazzilli, R., Faggiano, A., Pugliese, G., & Stigliano, A. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10132767 · Cited by 8
“[22] demonstrated that women with PAI experienced improved libido as well as mood and well-being when treated with a DHEA replacement therapy [23,24].”
BackgroundFang, Y., Hsieh, M., Hung, M.-S., Lin, Y., Kuo, L., Lu, M., Tzang, B., & Chen, V. C. (2020) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s265182 · Cited by 12
“In addition, untreated Addison’s patients had subnormal DHEAS levels, and DHEA replacement was reported to improve mood and fatigue scores among patients with Addison’s disease in a double-blind randomized trial.(33) DHEA may be one of the effective alternative drugs used in the treatment of depression.”
BackgroundThe role of androgens in hormone replacement therapy
Johnson, C., & Berman, J. R. (2005) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.6.11.1815 · Cited by 6
“2 Adrenal causes of androgen insufficiency Addison’s disease, or primary adrenal failure, occurs in 1 in 25,000 individuals and is characterised by chronic glucocorticoid and mineralocorticoid deficiency, which requires lifelong oral replacement [51].”
BackgroundHart, A. R. (2003) · Postgraduate medical journal · doi:10.1136/pmj.79.929.185 · Cited by 6
Schlienger, J.-L., Perrin, A., & Goichot, B. (2002) · La Revue de Médecine Interne · doi:10.1016/s0248-8663(02)00591-x · Cited by 6
Should Dehydroepiandrosterone be administered to women?
Me, W., & Kiseljak-Vassiliades, K. (2022) · Yearbook of Paediatric Endocrinology · doi:10.1530/ey.19.8.14 · Cited by 5
“They observed a significant improvement in in self-esteem and fatigue in the evening; however, they found no consistent effect on cognition or sexual arousal or function (28).”
BackgroundQuality of Life in Patients with Adrenal Insufficiency
Li, D. (2022) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2022.04.003 · Cited by 5
Heinzmann, J.-M., Kloiber, S. M., Mattos, G. E., Bielohuby, M., Palme, R., Holsboer, F., Uhr, M., Ising, M., Touma, C., & McIlwrick, S. (2015) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2015.07.542 · Cited by 17
Adrenal Insufficiency: Burden of Disease and Cost of Illness
Chauhan, R., & Lee, D. (2013) · doi:10.1016/j.jval.2013.08.651 · Cited by 5
How do you avoid and treat steroid side effects?
Travis, S. (2008) · Inflammatory Bowel Diseases · doi:10.1002/ibd.20649 · Cited by 5
Dietary supplements for female sexual dysfunction.
Boone, S. A., & Shields, K. (2005) · American Journal of Health-System Pharmacy · doi:10.1093/ajhp/62.6.574 · Cited by 5
Dehydroepiandrosterone-sulfate did not mitigate sickness behavior in mice.
Chen, J., & Johnson, R. W. (2004) · Physiology and Behavior · doi:10.1016/j.physbeh.2004.06.008 · Cited by 5
Dehydroepiandrosterone and Pregnenolone
Sih, R., Kamel, H. K., Horani, M. H., & Morley, J. E. (1999) · Humana Press eBooks · doi:10.1007/978-1-59259-700-0_15 · Cited by 3
Hasenmajer, V., de Alcubierre, D., Ferrari, D., Minnetti, M., Bonaventura, I., Pofi, R., Simeoli, C., Tomaselli, A., Sciarra, F., Bottillo, G., et al. (2024) · Andrology · doi:10.1111/andr.13635 · Cited by 4
“53,54 Similarly, we observed no correlation between adrenal androgens and sexual dysfunction in our male cohort, consistent with previous clinicaltrials 49,50 thatfoundnosignificantimprovementinsexualfunc-tion with DHEA replacement therapy in male patients with primary or secondary AI.”
IsHak, W. W., Mann, A., Manoukian, V., Pakhdikian, S., Chaudhry, M., Liu, A., & Bart, R. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.001 · Cited by 2
Associations of IGF-1 and Adrenal Androgens with Cognition in Childhood
Mäntyselkä, A., Haapala, E., Lindi, V., Häkkinen, M. R., Auriola, S., Jääskeläinen, J., & Lakka, T. (2019) · Hormone Research in Paediatrics · doi:10.1159/000501719 · Cited by 4
“Moreover, DHEA treatment has not improved cognitive function in Addison`s disease patients [7,8].”
BackgroundAntiglucocorticoids in psychiatry
McIsaac, S. A., Westrin, Å., & Young, A. H. (2009) · Advances in Psychiatric Treatment · doi:10.1192/apt.bp.105.001834 · Cited by 5
Aragno, M., Meineri, G., Vercellinatto, I., Bardini, P., Raimondo, S., Peiretti, P. G., Vercelli, A., Alloatti, G., Tomasinelli, C., Danni, O., et al. (2009) · Life Science · doi:10.1016/j.lfs.2009.04.020 · Cited by 4
“In agreement with several human studies showing only slight or no effect of DHEA on glucose homeostasis (Hunt et al. 2000; Callies et al. 2001; Christiansen et al. 2004), we found that DHEA supplementation did not affect the high plasma glucose levels induced by the HF diet, nor did it protect against hyperinsulinemia…”
BackgroundSubstitution mit Nebennierensteroiden
Hahner, S., & Allolio, B. (2008) · Der Internist · doi:10.1007/s00108-008-2122-z · Cited by 8
Dehydroepiandrosterone Administration in Treating Medical and Neuropsychiatric Disorders
Ritsner, M. S. (2008) · Springer eBooks · doi:10.1007/978-1-4020-6854-6_17 · Cited by 2
Sanders, R., Walsh, T., Baird, G. L., Atalay, M., Agarwal, S., Arcuri, D., Klinger, J., Mullin, C., Simmons, J., Singh, N., et al. (2025) · medRxiv · doi:10.1101/2025.08.01.25332627 · Cited by 3
Cognitive dysfunction in patients with primary adrenal insufficiency: A systematic review
Ramos-Levi, A. M., Cañada, E., & Matías‐Guiu, J. A. (2022) · Applied Neuropsychology Adult · doi:10.1080/23279095.2022.2090256 · Cited by 5
“In the former, the authors evaluated the effect of replacing with DHEA 50 mg/day for 12 weeks in 39 patients with AD using a double-blind randomized cross-over trial.”
BackgroundResultInfluentialSultana, T., Sarada, P., Srinivas, N., Reddy, C. H. S., Kumar, S. O., & Hasanuddin, S. (2021) · Iranian Journal of Orthodontics · doi:10.5812/ijo.116370 · Cited by 3
“DHEA is an adrenal precursor of steroid biosynthesis, which shows neurosteroid action on central nervous system (8).”
BackgroundThe Handbook of Wellness Medicine
Snellings, J. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182 · Cited by 11
Bender, S. L., Sherry, N., & Masia, R. (2013) · New England Journal of Medicine · doi:10.1056/nejmcpc1208145 · Cited by 5
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Andro and the Prosteroids: Bolting the Stable Door
Handelsman, D. J. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-2362 · Cited by 4
Adrenopause und Dehydroepiandrosteron: Pharmakotherapie versus Substitution
Römmler, A. (2003) · Gyn�kologisch-geburtshilfliche Rundschau · doi:10.1159/000069165 · Cited by 3
Hormone replacement therapy in an anti-ageing strategy for men
Comhaire, F. (2002) · doi:10.1258/136218002100321659 · Cited by 3
Measuring fatigue in medically unwell and distressed patients
Prince, M. I., & Jones, D. E. (2001) · Current Opinion in Psychiatry · doi:10.1097/00001504-200111000-00017 · Cited by 3
Lu, R.-H., Li, Y.-H., & Yao, W.-X. (2024) · Biostatistics · doi:10.1093/biostatistics/kxaf008 · Cited by 2
Dieppe, P. A., Goldingay, S., & Warber, S. L. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.042 · Cited by 3
Wellness Interventions in Patients Living with Chronic Medical Conditions
Steiner, A. J., Aguilar-Hernandez, L., Pizano, D. R., Dascal, J., & IsHak, W. W. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.014 · Cited by 1
Perera, D. M., & Moe, J. L. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.005 · Cited by 2
Well-Being and Work–Life Balance
Bolton, M. A., Lobben, I., Pruzinsky, T., & Stern, T. A. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.046 · Cited by 1
IsHak, W. W. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.052 · Cited by 2
Mental Disorders Due to a General Medical Condition
Beck, B. (2008) · Elsevier eBooks · doi:10.1016/b978-0-323-04743-2.50023-8 · Cited by 8
Junior doctors' working hours and the circadian rhythm of hormones.
Arlt, W. (2006) · Clinical medicine (London) · doi:10.7861/clinmedicine.6-2-127 · Cited by 2
Fatigue und Chronic-Fatigue-Syndrom in der Schwangerschaft
Richter, O., & Rath, W. (2005) · Der Gynäkologe · doi:10.1007/s00129-005-1706-0 · Cited by 2
Enfermedad de Addison. Tratamiento sustitutivo con glucocorticoides y su monitorización
Alonso, N., Granada, M. L., Lucas, A., Salinas, I., & Sanmartí, A. (2003) · Endocrinología y Nutrición · doi:10.1016/s1575-0922(03)74564-1 · Cited by 2
Is there a role for testosterone therapy in premenopausal women?
Shifren, J. L. (2003) · Menopause The Journal of The North American Menopause Society · doi:10.1097/01.gme.0000089029.10080.d9 · Cited by 2
Relations of androgens and selected aspects of human behavior
Thijssen, J. H. H. (2002) · Maturitas · doi:10.1016/s0378-5122(02)00014-2 · Cited by 2
“[36] Hunt PJ, Gurnell EM, Huppert FA, et al.”
BackgroundLaureti, S., Santeusanio, F., & Falorni, A. (2001) · Expert Opinion on Therapeutic Patents · doi:10.1517/13543776.11.12.1911 · Cited by 1
“Unfortunately, only preliminary data are available on the effects of DHEA administration in males with PAI [44].”
BackgroundInfluentialDHEA and the menopause: a new approach to HRT?
Raven, P., & Hinson, J. (2001) · doi:10.1258/136218001100321506 · Cited by 2
Doping Status of DHEA Treatment for Female Athletes with Adrenal Insufficiency
Handelsman, D. J., Matsumoto, A. M., & GERRARD, D. F. (2016) · Clinical Journal of Sport Medicine · doi:10.1097/jsm.0000000000000300 · Cited by 1
“In several studies, however, the 50 mg DHEA dose in women with adrenal failure causes androgenic side effects consistent with an excessive dose.(41,42,47,59,60) Such variability in androgenic response to DHEA dose may arise because OTC DHEA products, categorized as foods or “nutritional supplements” rather than pharma…”
Health-Related Quality of Life in Patients with Primary Adrenal Insufficiency
Zdrojowy-Wełna, A., Stańska, A., Halupczok-Żyła, J., Szczęśniak, D., & Bolanowski, M. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12237237 · Cited by 1
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Wellness Interventions in the Workplace
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The Role of Aesthetics in Wellness
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Allergic, Infectious, and Immunological Processes
Riaz, O., Orimaye, S. O., Al-Khateeb, T., Sodeke, P. O., Awujoola, A. O., & Goodkin, K. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.012 · Cited by 1
Androgen deficiency in women with adrenal insufficiency. Dehydroepiandrosterone. Review
Nuralieva, N., Yukina, M., Troshina, E., & Platonova, N. (2018) · Gynecology · doi:10.26442/2079-5696_2018.4.35-39 · Cited by 1
Adrenal Insufficiency - Aetiology, Diagnosis and Treatment
Akter, N., & Qureshi, N. K. (2015) · Delta Medical College Journal · doi:10.3329/dmcj.v3i1.22238
Dehydroepiandrosterone sulfate has not been substantiated as an anabolic hormone.
Dhatariya, K. (2008) · Archives of Internal Medicine · doi:10.1001/archinte.168.13.1470-a · Cited by 1
Therapies for adrenal insufficiency
Andrioli, M., Giraldi, F. P., Martin, M. D., & Cavagnini, F. (2007) · Expert Opinion on Therapeutic Patents · doi:10.1517/13543776.17.11.1323 · Cited by 3
“Some, but not all, studies [18] reported beneficial effects of DHEA treatment on mood, libido and quality of life in either sex [17] .”
BackgroundHypophysen- und Nebennierenoperationen
Flohr, F., & Seufert, J. (2007) · Der Internist · doi:10.1007/s00108-007-1854-5 · Cited by 1
Baschetti, R. (2003) · QJM : monthly journal of the Association of Physicians · doi:10.1093/qjmed/hcg079 · Cited by 1
Leonardi, D., Mintz, A., Dotson, A., & Mukai, J. (2001) · Rejuvenation Research · doi:10.1089/10945450152850678 · Cited by 1
Ooi, S. L., & Pak, S. C. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.033 · Cited by 1
Hughes, I. A., & Chatterjee, K. (2015) · Elsevier eBooks · doi:10.1016/b978-0-323-18907-1.00105-0 · Cited by 3
Self-citationFemale Androgen Insufficiency Syndrome
Garcia-Banigan, D. C., & Guay, A. T. (2004) · Elsevier eBooks · doi:10.1016/b978-0-7234-3266-1.50024-3 · Cited by 1
Hypophysenvorderlappeninsuffizienz
Hammer, F., & Arlt, W. (2004) · Der Internist · doi:10.1007/s00108-004-1216-5 · Cited by 1
“Mehrere randomisierte Doppelblindstudien haben in den letzten Jahren die positiven Effekte einer DHEA-Ersatztherapie auf Wohlbefinden, Stimmung und sexuelles Erleben bei Patienten mit primärer und sekundärer NNR-Insuffizienz nachgewiesen [25, 26, 27].”
BackgroundGatta, B., Monsaingeon, M., & Tabarin, A. (2003) · EMC - Endocrinologie - Nutrition · doi:10.1016/s1155-1941(03)00075-1 · Cited by 1
Behr, L. C., Kluttig, A., Simm, A., Mikolajczyk, R., Kraus, F. B., Sedding, D., Greiser, K. H., Wienke, A., & Großkopf, A. (2026) · npj Aging · doi:10.1038/s41514-026-00346-0
“While slight improvements in well-being were observed in women with adrenal insuf fi ciency 35 and patients with Addison ’ s disease under DHEAS-substitution 36 , most studies on healthy participants did not report signi fi cant impacts 38 – 40 .”
Bykova, A. Y., Bykov, Y. V., & Bekker, R. A. (2021) · Siberian Journal of Life Sciences and Agriculture · doi:10.12731/2658-6649-2021-13-4-316-351 · Cited by 1
“Существует множество теорий, объясняющих, как именно гипокортицизм может вызывать или провоцировать нервно-психические расстройства [7, 31, 50, 51, 71].”
Chaudhry, M., Gordon, A., Tadros, E., Sun, C., Tobia, G., & IsHak, W. W. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.019
Wellness in Endocrine and Metabolic Disorders
Clevenger, S., Eskander, L., Lin, T. Y., & IsHak, W. W. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.013
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EILBER, K. S., & Lee, U. J. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.010
Family Relations, Friendships, and Love
Alsup, S., Weisbaum, E., Vogel, T., & Siegel, D. J. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.047 · Cited by 1
Herrera, N., & IsHak, W. W. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.040
Mays, A. M., Whiteman, E., & Rosen, S. L. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.015
Louy, C., Sweet, C., Pollock, G. A., de Zagon, C., Louy, Z., Weiss, J. M., & Maher, D. P. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.017
The Personalized Wellness Life Plan
IsHak, W. W., Bart, R., Gohar, Y., Lorea, N., Eskander, L., Chang, T., Cohen, S., Furman, K., Nayyar, P. P., & DeBonis, K. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.050
Mindfulness, Meditation, and Yoga
Budd, K. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.028
Developing Purpose, Meaning, and Achievements
Vilhauer, J. S. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.041
The Role of Leisure, Recreation, and Play in Health and Well-Being
Payne, L. L., & An, J. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.048
Screening and Assessment Methods for Wellness
Greenberg, J. M., Castillo, E. G., IsHak, W. W., & Wells, K. B. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.002
Sleep, Rest, and Relaxation in Improving Wellness
Ngor, A., & IsHak, W. W. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.026
Emotional Intelligence and Its Role in Sustaining Fulfillment in Life
Sax, H. C., & Gewertz, B. L. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.038 · Cited by 1
Marin, K., Tobia, G., Bakhoum, A., Naghdechi, L., Korouri, S., & IsHak, W. W. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.027
Wellness in Cancer and Neoplastic Diseases
Bashmi, L., & IsHak, W. W. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.018
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Robbins, L., & Feldman, E. J. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.009
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Somjee, L., & Esbitt, S. A. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.003 · Cited by 1
Wellness Interventions for Physicians and Healthcare Professionals
Goldenberg, M., & Danovitch, I. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.021
Bucciarelli, A., Ellison, G. K., Sommer, E. K., & Spooner, H. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.036
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Postolov, L., & Gilberg-Lenz, S. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.031
Work, Love, Play, and Joie de Vivre
Groningen, N. V., IsHak, W. W., Ganjian, S., Ong, M. K., & Slusser, W. M. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.045
Connection, Compassion, and Community
Hedrick, R., & Jones, K. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.043
Circadian Rhythm in the Digital Age
Ezzat-Velinov, M., & Guarneri, M. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.035
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IsHak, W. W., & Herrera, N. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.008
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Hutchinson, T. A., & Hutchinson, N. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.049
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Pimental, P. A., O'Hara, J. B., Christopher, J., & Ciampanelli, A. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.030
Pharmaceuticals and Alternatives for Wellness
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Wellness in Children and Adolescents
Zanko, C., & Stuber, M. L. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108650182.016
Metadata
- Authors
- Hunt, P. J., Gurnell, E. M., Huppert, F. A., Richards, C., Prevost, A. T., Wass, J. A. H., Herbert, J., & Chatterjee, V. K. K.
- Affiliations
- University of Oxford (GB)
- University of Cambridge (GB)
- Community Medicine (A.T.P.), Cambridge, United Kingdom CB2 2QQ
- Departments of Medicine (E.M.G., C.R., V.K.K.C.), Cambridge, United Kingdom CB2 2QQ
- Venue
- The Journal of Clinical Endocrinology & Metabolism
- Publisher
- The Endocrine Society
- Published
- 2000-12-01
- Volume
- 85
- Issue
- 12
- Pages
- 4650-4656
- ISSN
- 0021-972X (ISSN-L)
- 1945-7197
- OpenAlex
- W2138758697
- Cited by
- 386
- References
- 45
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 8 · 2023: 3 · 2022: 6 · 2021: 9 · 2020: 58 · 2019: 1 · 2018: 7 · 2017: 4 · 2016: 10 · 2015: 13 · 2014: 15 · 2013: 5 · 2012: 12
- FWCI
- 16.47
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
- PubMed (publishedVersion)
- Research Portal (King's College London) (submittedVersion)
- Funders
- Hologic
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Keywords
- dehydroepiandrosterone, Addison's disease, DHEA replacement therapy, DHEA sulfate, adrenal insufficiency, mood, fatigue, self-esteem, well-being, testosterone, sex hormone-binding globulin, androstenedione, neurosteroids, central nervous system effects, glucocorticoid deficiency, mineralocorticoid deficiency
- MeSH terms
- Addison Disease, Adult, Affect, Aged, Body Composition, Cognition, Dehydroepiandrosterone, Double-Blind Method, Fatigue, Female, Hormones, Humans, Male, Middle Aged, Sexual Behavior, Bone Density, Cross-Over Studies, Dehydroepiandrosterone Sulfate, Hormone Replacement Therapy
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