Activation functions 1 and 2 of nuclear receptors: molecular strategies for transcriptional activation

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The coregulator exchange in transcriptional functions of nuclear receptors

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Structure of the MDM2 Oncoprotein Bound to the p53 Tumor Suppressor Transactivation Domain

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Nuclear Receptor Coregulators: Cellular and Molecular Biology

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Steroid Receptor Interactions with Heat Shock Protein and Immunophilin Chaperones*

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Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B

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Functional domains of the human estrogen receptor

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Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α

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Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid

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The human estrogen receptor has two independent nonacidic transcriptional activation functions

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A canonical structure for the ligand-binding domain of nuclear receptors

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Speeding molecular recognition by using the folding funnel: The fly-casting mechanism

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A structural role for hormone in the thyroid hormone receptor

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Structure and specificity of nuclear receptor–coactivator interactionsPreprint

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Multiplicity generates diversity in the retinoic acid signalling pathways

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Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition

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Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors.

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Role of the two activating domains of the oestrogen receptor in the cell‐type and promoter‐context dependent agonistic activity of the anti‐oestrogen 4‐hydroxytamoxifen.

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The chicken oestrogen receptor sequence: homology with v‐erbA and the human oestrogen and glucocorticoid receptors.

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Solution Structure of the KIX Domain of CBP Bound to the Transactivation Domain of CREB: A Model for Activator:Coactivator Interactions

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Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions

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A new class of yeast transcriptional activators.

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Transcriptional activation and nuclear targeting signals of the human androgen receptor.

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Structure and function of Nurr1 identifies a class of ligand-independent nuclear receptors

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The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function

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Coregulator codes of transcriptional regulation by nuclear receptors

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The retinoid signaling pathway: molecular and genetic analyses

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Nuclear receptor ligand-binding domains: three-dimensional structures, molecular interactions and pharmacological implications

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Stimulation of estrogen receptor-mediated transcription and alteration in the phosphorylation state of the rat uterine estrogen receptor by estrogen, cyclic adenosine monophosphate, and insulin-like growth factor-I

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FXXLF and WXXLF Sequences Mediate the NH2-terminal Interaction with the Ligand Binding Domain of the Androgen Receptor

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The AF1 and AF2 Domains of the Androgen Receptor Interact with Distinct Regions of SRC1

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The N-terminal region of the chicken progesterone receptor specifies target gene activation

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Specificity of ligand-dependent androgen receptor stabilization: receptor domain interactions influence ligand dissociation and receptor stability

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Disassembly of Transcriptional Regulatory Complexes by Molecular Chaperones

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Activation Function 2 in the Human Androgen Receptor Ligand Binding Domain Mediates Interdomain Communication with the NH2-terminal Domain

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Molecular Chaperone Machines: Chaperone Activities of the Cyclophilin Cyp-40 and the Steroid Aporeceptor-Associated Protein p23

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Dissection of the LXXLL Nuclear Receptor-Coactivator Interaction Motif Using Combinatorial Peptide Libraries: Discovery of Peptide Antagonists of Estrogen Receptors α and β

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Interaction between the Amino- and Carboxyl-terminal Regions of the Rat Androgen Receptor Modulates Transcriptional Activity and Is Influenced by Nuclear Receptor Coactivators

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Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism

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Activation function 2 (AF-2) of retinoic acid receptor and 9-cis retinoic acid receptor: Presence of a conserved autonomous constitutive activating domain and influence of the nature of the response element on AF-2 activity

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Distinct classes of transcriptional activating domains function by different mechanisms

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Steroid hormone receptors and their regulation by phosphorylation

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A third transactivation function (AF3) of human progesterone receptors located in the unique N-terminal segment of the B-isoform

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Transcription in yeast activated by a putative amphipathic α helix linked to a DNA binding unit

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Characterization of the ligand‐dependent transactivation domain of thyroid hormone receptor.

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2.1 Å Crystal Structure of Human PXR in Complex with the St. John's Wort Compound Hyperforin,

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Mammalian Glucocorticoid Receptor Derivatives Enhance Transcription in Yeast

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X-Ray Structure of the hRORα LBD at 1.63 Å

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The contribution of the N- and C-terminal regions of steroid receptors to activation of transcription is both receptor and cell-specific

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Induced α Helix in the VP16 Activation Domain upon Binding to a Human TAF

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Differential regulation of glucocorticoid receptor transcriptional activation via AF‐1‐associated proteins

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Transcription Activation by the Human Estrogen Receptor Subtypeβ (ERβ) Studied with ERβ and ERα Receptor Chimeras1

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Structural studies on nuclear receptors

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Intermolecular NH2-/carboxyl-terminal interactions in androgen receptor dimerization revealed by mutations that cause androgen insensitivity

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Characterization of the Amino-terminal Transcriptional Activation Function of the Human Estrogen Receptor in Animal and Yeast Cells

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Functional Interactions of the AF-2 Activation Domain Core Region of the Human Androgen Receptor with the Amino-Terminal Domain and with the Transcriptional Coactivator TIF2 (Transcriptional Intermediary Factor 2)

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Functional in Vivo Interaction between the Amino-Terminal, Transactivation Domain and the Ligand Binding Domain of the Androgen Receptor

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Immunochemical analysis of the glucocorticoid receptor: identification of a third domain separate from the steroid-binding and DNA-binding domains.

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Antagonist-occupied human progesterone receptors bound to DNA are functionally switched to transcriptional agonists by cAMP

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The p23 molecular chaperones act at a late step in intracellular receptor action to differentially affect ligand efficacies

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Structural characterization of a minimal functional transactivation domain from the human glucocorticoid receptor.

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Structural and functional analysis of the NF-kappa B p65 C terminus. An acidic and modular transactivation domain with the potential to adopt an alpha-helical conformation.

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Functional Domains of the Nuclear Receptor Hepatocyte Nuclear Factor 4

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Trinucleotide repeats in the human androgen receptor: a molecular basis for disease

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Conformational Analysis of the Androgen Receptor Amino-terminal Domain Involved in Transactivation

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The N-terminal Regions of Estrogen Receptor α and β Are Unstructured in Vitro and Show Different TBP Binding Properties

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Ligand-independent Activation of Steroid Receptors: New Roles for Old Players.

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Differential Recruitment of the Mammalian Mediator Subunit TRAP220 by Estrogen Receptors ERα and ERβ

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Ligand-dependent and -independent function of the transactivation regions of the human estrogen receptor in yeast

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Functional Interaction of the c-Myc Transactivation Domain with the TATA Binding Protein: Evidence for an Induced Fit Model of Transactivation Domain Folding

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Role of Acidic and Phosphorylated Residues in Gene Activation by the Glucocorticoid Receptor

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A Conserved C-Terminal Sequence That Is Deleted in v-ErbA is Essential for the Biological Activities of c-ErbA (the Thyroid Hormone Receptor)

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Interdomain Signaling in a Two-domain Fragment of the Human Glucocorticoid Receptor*

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Functional Interactions between the Estrogen Receptor and DRIP205, a Subunit of the Heteromeric DRIP Coactivator Complex

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Receptor Interacting Protein RIP140 Inhibits Both Positive and Negative Gene Regulation by Glucocorticoids

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Purification and characterization of the carboxyl-terminal transactivation domain of Vmw65 from herpes simplex virus type 1.

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A 22-Amino-Acid Peptide Restores DNA-Binding Activity to Dimerization-Defective Mutants of the Estrogen Receptor

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The N-terminal Region of the Human Progesterone A-receptor

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Electrostatic Modulation in Steroid Receptor Recruitment of LXXLL and FXXLF Motifs

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Transcriptional Activation Domain of the Herpesvirus Protein VP16 Becomes Conformationally Constrained upon Interaction with Basal Transcription Factors

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Structural motifs at protein‐protein interfaces: Protein cores versus two‐state and three‐state model complexes

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Involvement of the Transcription Factor IID Protein Complex in Gene Activation by the N-Terminal Transactivation Domain of the Glucocorticoid Receptor in Vitro

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Something old, some things new: The steroid receptor superfamily in drosophila

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Role of Important Hydrophobic Amino Acids in the Interaction between the Glucocorticoid Receptor τ1-Core Activation Domain and Target Factors

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Competition between Thyroid Hormone Receptor-associated Protein (TRAP) 220 and Transcriptional Intermediary Factor (TIF) 2 for Binding to Nuclear Receptors

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Role of the Ada Adaptor Complex in Gene Activation by the Glucocorticoid Receptor

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