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A Genetic Screen Identifies Hypothalamic Fgf15 as a Regulator of Glucagon Secretion

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Fgf15 Neurons of the Dorsomedial Hypothalamus Control Glucagon Secretion and Hepatic Gluconeogenesis

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Discovery of Natural Products as Novel and Potent FXR Antagonists by Virtual Screening

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Signalling cognition: The gut microbiota and hypothalamic-pituitary-adrenal axis

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Gut Microbiota Dysbiosis and Its Impact on Type 2 Diabetes: From Pathogenesis to Therapeutic Strategies

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Sedanolide alleviates DSS-induced colitis by modulating the intestinal FXR-SMPD3 pathway in mice

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Connecting the Gut Microbiota and Neurodegenerative Diseases: the Role of Bile Acids

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New insights into the role of Klotho in inflammation and fibrosis: molecular and cellular mechanisms

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Exploring the Significance of Gut Microbiota in Diabetes Pathogenesis and Management—A Narrative Review

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Gut microbiota–bile acid–intestinal Farnesoid X receptor signaling axis orchestrates cadmium-induced liver injury

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Tauroursodeoxycholic Acid Improves Nonalcoholic Fatty Liver Disease by Regulating Gut Microbiota and Bile Acid Metabolism

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Spaceflight alters host-gut microbiota interactions

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Type 2 Diabetes and the Multifaceted Gut-X Axes

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Astragalus saponins protect against extrahepatic and intrahepatic cholestatic liver fibrosis models by activation of farnesoid X receptor

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The role of bile acid metabolism in the occurrence and development of NAFLD

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Upregulation of Taurine Biosynthesis and Bile Acid Conjugation with Taurine through FXR in a Mouse Model with Human-like Bile Acid Composition

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Role of bile acids in overweight and obese children and adolescents

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Supplementation of Silymarin Alone or in Combination with Salvianolic Acids B and Puerarin Regulates Gut Microbiota and Its Metabolism to Improve High-Fat Diet-Induced NAFLD in Mice

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Primary Biliary Cholangitis and Primary Sclerosing Cholangitis Therapy Landscape

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Gut–Liver Axis as a Therapeutic Target for Drug-Induced Liver Injury

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Pharmacology of boldine: summary of the field and update on recent advances

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A Novel Frontier in Gut–Brain Axis Research: The Transplantation of Fecal Microbiota in Neurodegenerative Disorders

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Physical exercise plays a role in rebalancing the bile acids of enterohepatic axis in non‐alcoholic fatty liver disease

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Collaborative Metabolism: Gut Microbes Play a Key Role in Canine and Feline Bile Acid Metabolism

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Effects of cholesterol-lowering probiotics on non-alcoholic fatty liver disease in FXR gene knockout mice

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Progress in Biomarkers Related to Biliary Atresia

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Lingguizhugan oral solution alleviates MASLD by regulating bile acids metabolism and the gut microbiota through activating FXR/TGR5 signaling pathways

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Role of Microbiota-Modified Bile Acids in the Regulation of Intracellular Organelles and Neurodegenerative Diseases

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Roseburia intestinalis relieves intrahepatic cholestasis of pregnancy through bile acid/FXR-FGF15 in rats

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A Review: Cytochrome P450 in Alcoholic and Non-Alcoholic Fatty Liver Disease

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Review: interactions between microplastics and the gastrointestinal microbiome

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Triterpenoids from ilicis rotundae cortex ameliorate hyperlipidemia by affecting bile acids-hepatointestinal FXR axis

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Clostridium Scindens Protects Against Vancomycin‐Induced Cholestasis and Liver Fibrosis by Activating Intestinal FXR‐FGF15/19 Signaling

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ALDH2 deficiency exacerbates MCD-diet induced MASLD by modulating bile acid metabolism

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Bile Acid Diarrhea: From Molecular Mechanisms to Clinical Diagnosis and Treatment in the Era of Precision Medicine

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Advances in the pathophysiology, diagnosis and management of chronic diarrhoea from bile acid malabsorption: a systematic review

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Metabolite-mediated crosstalk: unraveling the interactions between gut microbiota and host in fatty liver hemorrhagic syndrome of laying hens

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Ampelopsis grossedentata improves type 2 diabetes mellitus through modulating the gut microbiota and bile acid metabolism

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Gut-Brain Axis Modulation of Metabolic Disorders: Exploring the Intertwined Neurohumoral Pathways and Therapeutic Prospects

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ZeXieYin formula alleviates atherosclerosis by regulating SBAs levels through the FXR/FGF15 pathway and restoring intestinal barrier integrity

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Dendrobium officinale aqueous extract regulates bile acid synthesis to improve acute alcoholic liver injury in mice

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Polysaccharide-mediated modulation of gut microbiota in the treatment of liver diseases: Promising approach with significant challenges

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The role of brain–liver–gut Axis in neurological disorders

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Microbial Metabolites as Ligands to Xenobiotic Receptors: Chemical Mimicry as Potential Drugs of the Future

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Therapeutic implications of obeticholic acid, a farnesoid X receptor agonist, in the treatment of liver fibrosis

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Flavonoids as modulators of gut-liver axis: emerging therapeutic strategies for MAFLD

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Suppression of the gut microbiota–bile acid– FGF19 axis in patients with atrial fibrillation

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Nuclear factor interleukin 3 and metabolic dysfunction-associated fatty liver disease development

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Edible fungi polysaccharides modulate gut microbiota and lipid metabolism: A review

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Discovery of (E)-3-(3-((2-Cyano-4′-dimethylaminobiphenyl-4-ylmethyl)cyclohexanecarbonylamino)-5-fluorophenyl)acrylic Acid Methyl Ester, an Intestine-Specific, FXR Partial Agonist for the Treatment of Nonalcoholic Steatohepatitis

Shim, S., Krishnaiah, M., Sankham, M. R., Kim, I., Lee, Y., Shin, I., Oh, A., Lee, H. J., Vu, T. N. L., Park, J., et al. (2022) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.2c00641 · Cited by 14 · see citing works

Antibiotic cocktail-induced changes in gut microbiota drive alteration of bile acid metabolism to restrain Th17 differentiation through the FXR–NLRP3 axis

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Contaminant biomonitoring augmented with a qPCR array indicates hepatic mRNA gene expression effects in wild-collected seabird embryos

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Fluoride induces hepatointestinal damage and vitamin B2 mitigation by regulating IL-17A and Bifidobacterium in ileum

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Multi-omics reveals the alleviating effect of berberine on ulcerative colitis through modulating the gut microbiome and bile acid metabolism in the gut-liver axis

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Gut microbiota-bile acids-glucagon like peptide-1 axis contributes the resistance to high fat diet-induced obesity in mice

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Water-soluble Poria cocos polysaccharide improves alcoholic liver disease via modulation of gut microbiota-mediated intestinal bile acids-farnesoid X receptor

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Unveiling the power of microenvironment in liver regeneration: an in-depth overview

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Triclosan exposure causes abnormal bile acid metabolism through IL-1β-NF-κB-Fxr signaling pathway

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A critical role for Phocaeicola vulgatus in negatively impacting metformin response in diabetes

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