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Cited by 634

The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.

Stroke Epidemiology and Risk Factor Management

Guzik, Amy, Bushnell, Cheryl·2017·Continuum
DOI 10.1212/con.0000000000000416
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Abstract

PURPOSE OF REVIEW: Death from stroke has decreased over the past decade, with stroke now the fifth leading cause of death in the United States. In addition, the incidence of new and recurrent stroke is declining, likely because of the increased use of specific prevention medications, such as statins and antihypertensives. Despite these positive trends in incidence and mortality, many strokes remain preventable. The major modifiable risk factors are hypertension, diabetes mellitus, tobacco smoking, and hyperlipidemia, as well as lifestyle factors, such as obesity, poor diet/nutrition, and physical inactivity. This article reviews the current recommendations for the management of each of these modifiable risk factors. RECENT FINDINGS: It has been documented that some blood pressure medications may increase variability of blood pressure and ultimately increase the risk for stroke. Stroke prevention typically includes antiplatelet therapy (unless an indication for anticoagulation exists), so the most recent evidence supporting use of these drugs is reviewed. In addition, emerging risk factors, such as obstructive sleep apnea, electronic cigarettes, and elevated lipoprotein (a), are discussed. SUMMARY: Overall, secondary stroke prevention includes a multifactorial approach. This article incorporates evidence from guidelines and published studies and uses an illustrative case study throughout the article to provide examples of secondary prevention management of stroke risk factors.

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Metadata

Authors
Guzik, A., & Bushnell, C.
Venue
Continuum
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2017-02
Volume
23
Issue
1
Pages
15-39
ISSN
  • 1080-2371 (ISSN-L)
  • 1538-6899
DOI
10.1212/con.0000000000000416
OpenAlex
W2586368855
Cited by
634
References
23
FWCI
23.00
Type
journal article
Language
en
Open access
closed

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