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The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Determination of language dominance using functional MRI: A comparison with the Wada test

Open access
Binder, J. R., Swanson, S. J., Hammeke, T. A., Morris, G. L., Mueller, W. M., Fischer, M., Benbadis, S., Frost, J.A., Rao, S. M., Haughton, V. M.·1996·Neurology

Abstract

We performed functional MRI (FMRI) in 22 consecutive epilepsy patients undergoing intracarotid amobarbital (Wada) testing and compared language lateralization measures obtained with the two procedures. FMRI used a single-word semantic decision task previously shown to activate lateralized language areas in normal adults. Correlation between the two tests was highly significant (r = 0.96; 95% CIs 0.90 to 0.98; p < 0.0001). These results validate the FMRI technique and suggest that "active" areas observed with this semantic processing task correspond to those underlying hemispheric dominance for language. This strong correlation observed supports the view that language lateralization is a continuous rather than a dichotomous variable. In addition to lateralization information, FMRI consistently demonstrated focal regions of activity in lateral frontal and temporo-parieto-occipital cortex. These functional maps may be helpful in defining the boundaries of surgical excisions.

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Metadata

Authors
Binder, J. R., Swanson, S. J., Hammeke, T. A., Morris, G. L., Mueller, W. M., Fischer, M., Benbadis, S., Frost, J. A., Rao, S. M., & Haughton, V. M.
Venue
Neurology
Published
1996-04
Volume
46
Issue
4
Pages
978-984
ISSN
  • 0028-3878 (ISSN-L)
  • 1526-632X
OpenAlex
W2131341295
Cited by
878
References
4
FWCI
19.44
Type
journal article
Language
en
Open access
bronze

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